Webster, A.C., E.V. Nagler, R.L. Morton, and P. Masson. 2017. Chronic kidney disease. Lancet 389: 1238–1252.

Article  PubMed  Google Scholar 

Romagnani, P., G. Remuzzi, R. Glassock, A. Levin, K.J. Jager, M. Tonelli, et al. 2017. Chronic kidney disease. Nature Reviews. Disease Primers 3: 17088.

Article  PubMed  Google Scholar 

Kalantar-Zadeh, K., T.H. Jafar, D. Nitsch, B.L. Neuen, and V. Perkovic. 2021. Chronic kidney disease. Lancet 398: 786–802.

Article  CAS  PubMed  Google Scholar 

Yang, C., H. Wang, X. Zhao, K. Matsushita, J. Coresh, L. Zhang, et al. 2020. CKD in China: Evolving spectrum and public health implications. American Journal of Kidney Diseases: The Official Journal of the National Kidney Foundation 76: 258–264.

Article  PubMed  Google Scholar 

Rookmaaker, M.B., and J.A. Joles. 2013. The nephron number counts–from womb to tomb. Nephrology, Dialysis, Transplantation 28: 1325–1328.

Article  PubMed  Google Scholar 

Burton, G.J., A.L. Fowden, and K.L. Thornburg. 2016. Placental origins of chronic disease. Physiological Reviews 96: 1509–1565.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wesolowski, S.R., K.C. Kasmi, K.R. Jonscher, and J.E. Friedman. 2017. Developmental origins of NAFLD: A womb with a clue. Nature Reviews. Gastroenterology & Hepatology 14: 81–96.

Article  CAS  Google Scholar 

Hoffman, D.J., T.L. Powell, E.S. Barrett, and D.B. Hardy. 2021. Developmental origins of metabolic diseases. Physiological Reviews 101: 739–795.

Article  CAS  PubMed  Google Scholar 

Perico, N., D. Askenazi, M. Cortinovis, and G. Remuzzi. 2018. Maternal and environmental risk factors for neonatal AKI and its long-term consequences. Nature Reviews. Nephrology 14: 688–703.

Article  CAS  PubMed  Google Scholar 

Hsu, C.W., K.T. Yamamoto, R.K. Henry, A.J. De Roos, and J.T. Flynn. 2014. Prenatal risk factors for childhood CKD. Journal of the American Society of Nephrology: JASN 25: 2105–2111.

Article  PubMed  PubMed Central  Google Scholar 

Hsu, C.N., and Y.L. Tain. 2021. Adverse impact of environmental chemicals on developmental origins of kidney disease and hypertension. Frontiers in Endocrinology (Lausanne) 12: 745716.

Article  Google Scholar 

Luyckx, V.A., N. Perico, M. Somaschini, D. Manfellotto, H. Valensise, I. Cetin, et al. 2017. A developmental approach to the prevention of hypertension and kidney disease: A report from the Low Birth Weight and Nephron Number Working Group. Lancet 390: 424–428.

Article  PubMed  PubMed Central  Google Scholar 

Cargill, K.R., T. Chiba, A. Murali, E. Mukherjee, E. Crinzi, and S. Sims-Lucas. 2020. Prenatal hypoxia increases susceptibility to kidney injury. PLoS ONE 15: e0229618.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, H., Y. Zhu, X. Zhao, H. He, J. Luo, Y. Ao, et al. 2020. Prenatal ethanol exposure increased the susceptibility of adult offspring rats to glomerulosclerosis. Toxicology Letters 321: 44–53.

Article  CAS  PubMed  Google Scholar 

Guo, W., X. Guan, X. Pan, X. Sun, F. Wang, Y. Ji, et al. 2016. Post-natal inhibition of NF-kappaB activation prevents renal damage caused by prenatal LPS exposure. PLoS ONE 11: e0153434.

Article  PubMed  PubMed Central  Google Scholar 

Hetz, C., K. Zhang, and R.J. Kaufman. 2020. Mechanisms, regulation and functions of the unfolded protein response. Nature Reviews Molecular Cell Biology 21: 421–438.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hetz, C., and F.R. Papa. 2018. The unfolded protein response and cell fate control. Molecular Cell 69: 169–181.

Article  CAS  PubMed  Google Scholar 

Cybulsky, A.V. 2017. Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases. Nature Reviews. Nephrology 13: 681–696.

Article  CAS  PubMed  Google Scholar 

Cao, D., W. Wang, S. Li, W. Lai, X. Huang, J. Zhou, et al. 2019. TLR2-deficiency promotes prenatal LPS exposure-induced offspring hyperlipidemia. Frontiers in Physiology 10: 1102.

Article  PubMed  PubMed Central  Google Scholar 

Cao, D., Y. Liu, X. Chen, J. Liu, J. Liu, W. Lai, et al. 2022. Activation of iNKT cells at the maternal-fetal interface predisposes offspring to cardiac injury. Circulation 145: 1032–1035.

Article  CAS  PubMed  Google Scholar 

Ludwig-Portugall, I., E. Bartok, E. Dhana, B.D. Evers, M.J. Primiano, J.P. Hall, et al. 2016. An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice. Kidney International 90: 525–539.

Article  CAS  PubMed  Google Scholar 

Qin, S., X. Chen, M. Gao, J. Zhou, and X. Li. 2017. Prenatal exposure to lipopolysaccharide induces PTX3 expression and results in obesity in mouse offspring. Inflammation 40: 1847–1861.

Article  CAS  PubMed  Google Scholar 

Watanabe, S., N.S. Markov, Z. Lu, R. Piseaux Aillon, S. Soberanes, C.E. Runyan, et al. 2021. Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis. Proceedings of the National Academy of Sciences of the United States of America 118 (20): e2101100118.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kramer, A., J. Green, J. Pollard Jr., and S. Tugendreich. 2014. Causal analysis approaches in Ingenuity Pathway Analysis. Bioinformatics 30: 523–530.

Article  PubMed  Google Scholar 

Mulay, S.R., S. Steiger, C. Shi, and H.J. Anders. 2020. A guide to crystal-related and nano- or microparticle-related tissue responses. FEBS Journal 287: 818–832.

Article  CAS  PubMed  Google Scholar 

van Anken, E., A. Bakunts, C.A. Hu, S. Janssens, and R. Sitia. 2021. Molecular evaluation of endoplasmic reticulum homeostasis meets humoral immunity. Trends in Cell Biology 31 (7): 529–541.

Article  PubMed  PubMed Central  Google Scholar 

Grootjans, J., A. Kaser, R.J. Kaufman, and R.S. Blumberg. 2016. The unfolded protein response in immunity and inflammation. Nature Reviews Immunology 16: 469–484.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Oslowski, C.M., T. Hara, B. O’Sullivan-Murphy, K. Kanekura, S. Lu, M. Hara, et al. 2012. Thioredoxin-interacting protein mediates ER stress-induced beta cell death through initiation of the inflammasome. Cell Metabolism 16: 265–273.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bronner, D.N., B.H. Abuaita, X. Chen, K.A. Fitzgerald, G. Nunez, Y. He, et al. 2015. Endoplasmic reticulum stress activates the inflammasome via NLRP3- and Caspase-2-Driven mitochondrial damage. Immunity 43: 451–462.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lerner, A.G., J.P. Upton, P.V. Praveen, R. Ghosh, Y. Nakagawa, A. Igbaria, et al. 2012. IRE1alpha induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metabolism 16: 250–264.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hetz, C., J.M. Axten, and J.B. Patterson. 2019. Pharmacological targeting of the unfolded protein response for disease intervention. Nature Chemical Biology 15: 764–775.