Schett, G., and E. Gravallese. 2012. Bone erosion in rheumatoid arthritis: Mechanisms, diagnosis and treatment. Nature Reviews Rheumatology 8 (11): 656–664. https://doi.org/10.1038/nrrheum.2012.153.
Article CAS PubMed PubMed Central Google Scholar
Komatsu, N., and H. Takayanagi. 2022. Mechanisms of joint destruction in rheumatoid arthritis - immune cell-fibroblast-bone interactions. Nature Reviews Rheumatology 18 (7): 415–429. https://doi.org/10.1038/s41584-022-00793-5.
Article CAS PubMed Google Scholar
Shim, J.H., Z. Stavre, and E.M. Gravallese. 2018. Bone loss in rheumatoid arthritis: Basic mechanisms and clinical implications. Calcified Tissue International 102 (5): 533–546. https://doi.org/10.1007/s00223-017-0373-1.
Article CAS PubMed Google Scholar
Liang, Y., H. Xu, T. Cheng, Y. Fu, H. Huang, W. Qian, J. Wang, et al. 2022. Gene activation guided by nascent RNA-bound transcription factors. Nature Communications 13 (1): 7329. https://doi.org/10.1038/s41467-022-35041-7.
Article CAS PubMed PubMed Central Google Scholar
Hnisz, D., B.J. Abraham, T.I. Lee, A. Lau, V. Saint-Andre, A.A. Sigova, H.A. Hoke, et al. 2013. Super-enhancers in the control of cell identity and disease. Cell 155 (4): 934–947. https://doi.org/10.1016/j.cell.2013.09.053.
Article CAS PubMed Google Scholar
Sabari, B.R., Dall'Agnese, A., Boija, A., Klein, I.A., Coffey, E.L., Shrinivas, K., Abraham, B.J. et al. 2018. Coactivator condensation at super-enhancers links phase separation and gene control. Science 361 (6400). https://doi.org/10.1126/science.aar3958
Yamagata, K., S. Nakayamada, and Y. Tanaka. 2020. Critical roles of super-enhancers in the pathogenesis of autoimmune diseases. Inflammation and Regeneration 40: 16. https://doi.org/10.1186/s41232-020-00124-9.
Article CAS PubMed PubMed Central Google Scholar
Han, Z., and W. Li. 2022. Enhancer RNA: What we know and what we can achieve. Cell Proliferation 55 (4): e13202. https://doi.org/10.1111/cpr.13202.
Article CAS PubMed PubMed Central Google Scholar
Wang, Y., Zhang, C., Wang, Y., Liu, X., Zhang, Z. 2022. Enhancer RNA (eRNA) in Human Diseases. International Journal of Molecular Science 23 (19). https://doi.org/10.3390/ijms231911582
Hnisz, D., K. Shrinivas, R.A. Young, A.K. Chakraborty, and P.A. Sharp. 2017. A phase separation model for transcriptional control. Cell 169 (1): 13–23. https://doi.org/10.1016/j.cell.2017.02.007.
Article CAS PubMed PubMed Central Google Scholar
Li, Q., X. Liu, J. Wen, X. Chen, B. Xie, and Y. Zhao. 2023. Enhancer RNAs: Mechanisms in transcriptional regulation and functions in diseases. Cell Communication and Signaling: CCS 21 (1): 191. https://doi.org/10.1186/s12964-023-01206-0.
Article CAS PubMed PubMed Central Google Scholar
Bae, S., K. Kim, K. Kang, H. Kim, M. Lee, B. Oh, K. Kaneko, et al. 2023. RANKL-responsive epigenetic mechanism reprograms macrophages into bone-resorbing osteoclasts. Cellular & Molecular Immunology 20 (1): 94–109. https://doi.org/10.1038/s41423-022-00959-x.
Wang, J., Q. Fan, T. Yu, and Y. Zhang. 2022. Identifying the hub genes and immune cell infiltration in synovial tissue between osteoarthritic and rheumatoid arthritic patients by bioinformatic approach. Current Pharmaceutical Design 28 (6): 497–509. https://doi.org/10.2174/1381612827666211104154459.
Article CAS PubMed Google Scholar
Feng, Z., J. Zhou, Y. Liu, R. Xia, Q. Li, L. Yan, Q. Chen, et al. 2021. Epithelium- and endothelium-derived exosomes regulate the alveolar macrophages by targeting RGS1 mediated calcium signaling-dependent immune response. Cell Death and Differentiation 28 (7): 2238–2256. https://doi.org/10.1038/s41418-021-00750-x.
Article CAS PubMed PubMed Central Google Scholar
Takayanagi, H., S. Kim, T. Koga, H. Nishina, M. Isshiki, H. Yoshida, A. Saiura, et al. 2002. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Developmental Cell 3 (6): 889–901. https://doi.org/10.1016/s1534-5807(02)00369-6.
Article CAS PubMed Google Scholar
Alexander, M.S., X. Shi, K.A. Voelker, R.W. Grange, J.A. Garcia, R.E. Hammer, and D.J. Garry. 2010. Foxj3 transcriptionally activates Mef2c and regulates adult skeletal muscle fiber type identity. Developmental Biology 337 (2): 396–404. https://doi.org/10.1016/j.ydbio.2009.11.015.
Article CAS PubMed Google Scholar
Song, G., T. Feng, R. Zhao, Q. Lu, Y. Diao, Q. Guo, Z. Wang, et al. 2019. CD109 regulates the inflammatory response and is required for the pathogenesis of rheumatoid arthritis. Annals of the Rheumatic Diseases 78 (12): 1632–1641. https://doi.org/10.1136/annrheumdis-2019-215473.
Article CAS PubMed Google Scholar
Alabarse, P.V.G., P.S. Lora, J.M.S. Silva, R.C.E. Santo, E.C. Freitas, M.S. de Oliveira, A.S. Almeida, et al. 2018. Collagen-induced arthritis as an animal model of rheumatoid cachexia. Journal of Cachexia, Sarcopenia and Muscle 9 (3): 603–612. https://doi.org/10.1002/jcsm.12280.
Article PubMed PubMed Central Google Scholar
Yang, S., and Y.P. Li. 2007. RGS12 is essential for RANKL-evoked signaling for terminal differentiation of osteoclasts in vitro. Journal of Bone and Mineral Research 22 (1): 45–54. https://doi.org/10.1359/jbmr.061007.
Article CAS PubMed Google Scholar
Ito, Y., D. Inoue, S. Kido, and T. Matsumoto. 2005. c-Fos degradation by the ubiquitin-proteasome proteolytic pathway in osteoclast progenitors. Bone 37 (6): 842–849. https://doi.org/10.1016/j.bone.2005.04.030.
Article CAS PubMed Google Scholar
Mousavi, K., H. Zare, S. Dell’orso, L. Grontved, G. Gutierrez-Cruz, A. Derfoul, G.L. Hager, et al. 2013. eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci. Molecular Cell 51 (5): 606–617. https://doi.org/10.1016/j.molcel.2013.07.022.
Article CAS PubMed PubMed Central Google Scholar
Onoguchi, M., Y. Hirabayashi, H. Koseki, and Y. Gotoh. 2012. A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development. Proceedings of the National Academy of Sciences U S A 109 (42): 16939–16944. https://doi.org/10.1073/pnas.1202956109.
Okada, Y., D. Wu, G. Trynka, T. Raj, C. Terao, K. Ikari, Y. Kochi, et al. 2014. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature 506 (7488): 376–381. https://doi.org/10.1038/nature12873.
Article CAS PubMed Google Scholar
Vahedi, G., Y. Kanno, Y. Furumoto, K. Jiang, S.C. Parker, M.R. Erdos, S.R. Davis, et al. 2015. Super-enhancers delineate disease-associated regulatory nodes in T cells. Nature 520 (7548): 558–562. https://doi.org/10.1038/nature14154.
Article CAS PubMed PubMed Central Google Scholar
Ohkura, N., and S. Sakaguchi. 2020. Transcriptional and epigenetic basis of Treg cell development and function: Its genetic anomalies or variations in autoimmune diseases. Cell Research 30 (6): 465–474. https://doi.org/10.1038/s41422-020-0324-7.
Article CAS PubMed PubMed Central Google Scholar
Hah, N., C. Benner, L.W. Chong, R.T. Yu, M. Downes, and R.M. Evans. 2015. Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs. Proceedings of the National Academy of Sciences U S A 112 (3): E297-302. https://doi.org/10.1073/pnas.1424028112.
Zhang, R., C. Chang, Y. Jin, L. Xu, P. Jiang, K. Wei, L. Xu, et al. 2022. Identification of DNA methylation-regulated differentially expressed genes in RA by integrated analysis of DNA methylation and RNA-Seq data. Journal of Translational Medicine 20 (1): 481. https://doi.org/10.1186/s12967-022-03664-5.
留言 (0)