Bretones G, Delgado MD, León J. Myc and cell cycle control. Biochim Biophys Acta (BBA) - Gene Regul Mech. 2015;1849(5):506–16.

Article  CAS  Google Scholar 

Camicioli R, Moore MM, Kinney A, Corbridge E, Glassberg K, Kaye JA. Parkinson’s disease is associated with hippocampal atrophy. Mov Disord. 2003;18(7):784–90.

Article  PubMed  Google Scholar 

Cui Y, Zhang C, Ma S, Li Z, Wang W, Li Y, et al. RNA m6A demethylase FTO-mediated epigenetic up-regulation of LINC00022 promotes tumorigenesis in esophageal squamous cell carcinoma. J Exp Clin Cancer Res. 2021;40(1):294.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Donovan MH, Yazdani U, Norris RD, Games D, German DC, Eisch AJ. Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer’s disease. J Comp Neurol. 2006;495(1):70–83.

Article  PubMed  Google Scholar 

el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, et al. WAF1, a potential mediator of p53 tumor suppression. Cell. 1993;75(4):817–25.

Article  CAS  PubMed  Google Scholar 

Eriksson PS, Perfilieva E, Bjork-Eriksson T, Alborn AM, Nordborg C, Peterson DA, et al. Neurogenesis in the adult human hippocampus. Nat Med. 1998;4(11):1313–7.

Article  CAS  PubMed  Google Scholar 

Fu Y, Dominissini D, Rechavi G, He C. Gene expression regulation mediated through reversible m(6)A RNA methylation. Nat Rev Genet. 2014;15(5):293–306.

Article  CAS  PubMed  Google Scholar 

Geng S, Peng W, Wang X, Hu X, Liang H, Hou J, et al. ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination. Cell Death Dis. 2022;13(6):564.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 1993;75(4):805–16.

Article  CAS  PubMed  Google Scholar 

Hernandez Borrero LJ, El-Deiry WS. Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting. Biochim Biophys Acta Rev Cancer. 2021;1876(1):188556.

Article  CAS  PubMed  Google Scholar 

Huang Y, Zhu Y, Yang J, Pan Q, Zhao J, Song M, et al. CMTM6 inhibits tumor growth and reverses chemoresistance by preventing ubiquitination of p21 in hepatocellular carcinoma. Cell Death Dis. 2022;13(3):251.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ivanovska I, Ball AS, Diaz RL, Magnus JF, Kibukawa M, Schelter JM, et al. MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol Cell Biol. 2008;28(7):2167–74.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kamle M, Mahato DK, Gupta A, Pandhi S, Sharma B, Dhawan K, et al. Deoxynivalenol: an overview on occurrence, chemistry, biosynthesis, health effects and its detection, management, and control strategies in food and feed. Microbiol Res. 2022;13(2):292–314.

Article  CAS  Google Scholar 

Karimian A, Ahmadi Y, Yousefi B. Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage. DNA Repair (amst). 2016;42:63–71.

Article  CAS  PubMed  Google Scholar 

Li D, Ye Y, Deng L, Ma H, Fan X, Zhang Y, et al. Gene expression profiling analysis of deoxynivalenol-induced inhibition of mouse thymic epithelial cell proliferation. Environ Toxicol Pharmacol. 2013;36(2):557–66.

Article  PubMed  Google Scholar 

Li L, Zang L, Zhang F, Chen J, Shen H, Shu L, et al. Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis. Hum Mol Genet. 2017;26(13):2398–411.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Llorens-Martin M, Rabano A, Avila J. The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology. Front Neurosci. 2015;9:526.

PubMed  Google Scholar 

Maeda Y, Isomura A, Masaki T, Kageyama R. Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21. Cell Rep. 2023;42(5):112520.

Article  CAS  PubMed  Google Scholar 

Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci. 2000;20(24):9104–10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Napione L, Strasly M, Meda C, Mitola S, Alvaro M, Doronzo G, et al. IL-12-dependent innate immunity arrests endothelial cells in G0–G1 phase by a p21Cip1/Waf1-mediated mechanism. Angiogenesis. 2012;15(4):713–25.

Article  CAS  PubMed  Google Scholar 

Ouyang D, Hong T, Fu M, Li Y, Zeng L, Chen Q, et al. METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer. Breast Cancer Res. 2023;25(1):19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qiu J, Takagi Y, Harada J, Rodrigues N, Moskowitz MA, Scadden DT, et al. Regenerative response in ischemic brain restricted by p21cip1/waf1. J Exp Med. 2004;199(7):937–45.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ruan DY, Li T, Wang YN, Meng Q, Li Y, Yu K, et al. FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis. Oncogene. 2021;40(33):5168–81.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sava V, Velasquez A, Song S, Sanchez-Ramos J. Adult hippocampal neural stem/progenitor cells in vitro are vulnerable to the mycotoxin ochratoxin-A. Toxicol Sci. 2007;98(1):187–97.

Article  CAS  PubMed  Google Scholar 

Schafer KA. The cell cycle: a review. Vet Pathol. 1998;35(6):461–78.

Article  CAS  PubMed  Google Scholar 

Schwartz S, Mumbach MR, Jovanovic M, Wang T, Maciag K, Bushkin GG, et al. Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5’ sites. Cell Rep. 2014;8(1):284–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Scoville WB, Milner B. Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry. 1957;20(1):11–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi H, Wei J, He C. Where, when, and how: context-dependent functions of RNA methylation writers, readers, and erasers. Mol Cell. 2019;74(4):640–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi J, Zhang Q, Yin X, Ye J, Gao S, Chen C, et al. Stabilization of IGF2BP1 by USP10 promotes breast cancer metastasis via CPT1A in an m6A-dependent manner. Int J Biol Sci. 2023;19(2):449–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Singhal G, Morgan J, Jawahar MC, Corrigan F, Jaehne EJ, Toben C, et al. The effects of short-term and long-term environmental enrichment on locomotion, mood-like behavior, cognition and hippocampal gene expression. Behav Brain Res. 2019;368:111917.

Article  PubMed