Annane D, Ouanes-Besbes L, de Backer D, Du B, Gordon AC, Hernandez G, Olsen KM, Osborn TM, Peake S, Russell JA, Cavazzoni SZ (2018) A global perspective on vasoactive agents in shock. Intensive Care Med 44:833–846
Article CAS PubMed Google Scholar
Vahdatpour C, Collins D, Goldberg S (2019) Cardiogenic shock. J Am Heart Assoc 8:e011991
Article PubMed PubMed Central Google Scholar
Russell JA (2019) Vasopressor therapy in critically ill patients with shock. Intensive Care Med 45:1503–1517
Article CAS PubMed Google Scholar
Andreis DT, Singer M (2016) Catecholamines for inflammatory shock: a Jekyll-and-Hyde conundrum. Intensive Care Med 42:1387–1397
Article CAS PubMed Google Scholar
Triposkiadis F, Karayannis G, Giamouzis G, Skoularigis J, Louridas G, Butler J (2009) The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol 54:1747–1762
Article CAS PubMed Google Scholar
Lymperopoulos A, Rengo G, Koch WJ (2013) Adrenergic nervous system in heart failure: pathophysiology and therapy. Circ Res 113:739–753
Article CAS PubMed Google Scholar
Schmittinger CA, Torgersen C, Luckner G, Schroder DC, Lorenz I, Dünser MW (2012) Adverse cardiac events during catecholamine vasopressor therapy: a prospective observational study. Intensive Care Med 38:950–958
Article CAS PubMed Google Scholar
Wallner M, Duran JM, Mohsin S, Troupes CD, Vanhoutte D, Borghetti G, Vagnozzi RJ, Gross P, Yu D, Trappanese DM, Kubo H, Toib A, Sharp TE 3rd, Harper SC, Volkert MA, Starosta T, Feldsott EA, Berretta RM, Wang T, Barbe MF, Molkentin JD, Houser SR (2016) Acute catecholamine exposure causes reversible myocyte injury without cardiac regeneration. Circ Res 119:865–879
Article CAS PubMed PubMed Central Google Scholar
Litvinukova M, Talavera-Lopez C, Maatz H, Reichart D, Worth CL, Lindberg EL, Kanda M, Polanski K, Heinig M, Lee M, Nadelmann ER, Roberts K, Tuck L, Fasouli ES, DeLaughter DM, McDonough B, Wakimoto H, Gorham JM, Samari S, Mahbubani KT, Saeb-Parsy K, Patone G, Boyle JJ, Zhang H, Viveiros A, Oudit GY, Bayraktar OA, Seidman JG, Seidman CE, Noseda M, Hubner N, Teichmann SA (2020) Cells of the adult human heart. Nature 588:466–472
Article CAS PubMed PubMed Central Google Scholar
Myagmar BE, Flynn JM, Cowley PM, Swigart PM, Montgomery MD, Thai K, Nair D, Gupta R, Deng DX, Hosoda C, Melov S, Baker AJ, Simpson PC (2017) Adrenergic receptors in individual ventricular myocytes: the beta-1 and Alpha-1B are in all cells, the Alpha-1A is in a subpopulation, and the Beta-2 and Beta-3 are mostly absent. Circ Res 120:1103–1115
Article CAS PubMed PubMed Central Google Scholar
Engelhardt S, Hein L, Wiesmann F, Lohse MJ (1999) Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA 96:7059–7064
Article CAS PubMed PubMed Central Google Scholar
Engelhardt S, Hein L, Dyachenkow V, Kranias EG, Isenberg G, Lohse MJ (2004) Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation. Circulation 109:1154–1160
Article CAS PubMed Google Scholar
Chang SC, Ren S, Rau CD, Wang JJ (2018) Isoproterenol-Induced heart failure mouse model using osmotic pump implantation. Methods Mol Biol 1816:207–220
Article CAS PubMed PubMed Central Google Scholar
Grant MKO, Abdelgawad IY, Lewis CA, Seelig D, Zordoky BN (2020) Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction. PLoS ONE 15:e0232507
Article CAS PubMed PubMed Central Google Scholar
Dewenter M, Pan J, Knodler L, Tzschockel N, Henrich J, Cordero J, Dobreva G, Lutz S, Backs J, Wieland T, Vettel C (2022) Chronic isoprenaline/phenylephrine vs. exclusive isoprenaline stimulation in mice: critical contribution of alpha1-adrenoceptors to early cardiac stress responses. Basic Res Cardiol 117:15
Article CAS PubMed PubMed Central Google Scholar
Akhtar MM, Cammann VL, Templin C, Ghadri JR, Luscher TF (2023) Takotsubo syndrome: getting closer to its causes. Cardiovasc Res 119:1480–1494
Article CAS PubMed Google Scholar
Ghadri JR, Kato K, Cammann VL, Gili S, Jurisic S, Di Vece D, Candreva A, Ding KJ, Micek J, Szawan KA, Bacchi B, Bianchi R, Levinson RA, Wischnewsky M, Seifert B, Schlossbauer SA, Citro R, Bossone E, Munzel T, Knorr M, Heiner S, D’Ascenzo F, Franke J, Sarcon A, Napp LC, Jaguszewski M, Noutsias M, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschope C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuss G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Horowitz J, Kozel M, Tousek P, Widimsky P, Gilyarova E, Shilova A, Gilyarov M, Winchester DE, Ukena C, Bax JJ, Prasad A, Bohm M, Luscher TF, Ruschitzka F, Templin C (2018) Long-term prognosis of patients with Takotsubo syndrome. J Am Coll Cardiol 72:874–882
Werhahn SM, Kreusser JS, Hagenmuller M, Beckendorf J, Diemert N, Hoffmann S, Schultz JH, Backs J, Dewenter M (2021) Adaptive versus maladaptive cardiac remodelling in response to sustained beta-adrenergic stimulation in a new “ISO on/off model.” PLoS ONE 16:e0248933
Article CAS PubMed PubMed Central Google Scholar
Gilsbach R, Preissl S, Gruning BA, Schnick T, Burger L, Benes V, Wurch A, Bonisch U, Gunther S, Backofen R, Fleischmann BK, Schubeler D, Hein L (2014) Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease. Nat Commun 5:5288
Article CAS PubMed Google Scholar
Deng L, Pollmeier L, Bednarz R, Cao C, Laurette P, Wirth L, Mamazhakypov A, Bode C, Hein L, Gilsbach R, Lother A (2024) Atlas of cardiac endothelial cell enhancer elements linking the mineralocorticoid receptor to pathological gene expression. Sci Adv 10:eadj5101
Article CAS PubMed PubMed Central Google Scholar
Afgan E, Baker D, Batut B, van den Beek M, Bouvier D, Cech M, Chilton J, Clements D, Coraor N, Gruning BA, Guerler A, Hillman-Jackson J, Hiltemann S, Jalili V, Rasche H, Soranzo N, Goecks J, Taylor J, Nekrutenko A, Blankenberg D (2018) The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update. Nucleic Acids Res 46:W537–W544
Article CAS PubMed PubMed Central Google Scholar
Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR (2013) STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29:15–21
Article CAS PubMed Google Scholar
Anders S, Pyl PT, Huber W (2015) HTSeq–a Python framework to work with high-throughput sequencing data. Bioinformatics 31:166–169
Article CAS PubMed Google Scholar
Love MI, Huber W, Anders S (2014) Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 15:550
Article PubMed PubMed Central Google Scholar
Lopez-Delisle L, Rabbani L, Wolff J, Bhardwaj V, Backofen R, Gruning B, Ramirez F, Manke T (2021) pyGenomeTracks: reproducible plots for multivariate genomic datasets. Bioinformatics 37:422–423
Article CAS PubMed Google Scholar
Bindea G, Mlecnik B, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman WH, Pages F, Trajanoski Z, Galon J (2009) ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics 25:1091–1093
Article CAS PubMed PubMed Central Google Scholar
Lother A, Bondareva O, Saadatmand AR, Pollmeier L, Hardtner C, Hilgendorf I, Weichenhan D, Eckstein V, Plass C, Bode C, Backs J, Hein L, Gilsbach R (2021) Diabetes changes gene expression but not DNA methylation in cardiac cells. J Mol Cell Cardiol 151:74–87
Article CAS PubMed Google Scholar
McLean CY, Bristor D, Hiller M, Clarke SL, Schaar BT, Lowe CB, Wenger AM, Bejerano G (2010) GREAT improves functional interpretation of cis-regulatory regions. Nat Biotechnol 28:495–501
Article CAS PubMed PubMed Central Google Scholar
Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK (2010) Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell 38:576–589
Article CAS PubMed PubMed Central Google Scholar
Lother A, Kohl P (2023) The heterocellular heart: identities, interactions, and implications for cardiology. Basic Res Cardiol 118:30
Article PubMed PubMed Central Google Scholar
Barton M, Yanagisawa M (2019) Endothelin: 30 years from discovery to therapy. Hypertension 74:1232–1265
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