Linden R, Cordeiro Y, Lima LMTR (2012) Allosteric function and dysfunction of the prion protein. Cell Mol Life Sci 69:1105–1124. https://doi.org/10.1007/s00018-011-0847-7
CAS Article PubMed Google Scholar
Castle AR, Gill AC (2017) Physiological functions of the cellular prion protein. Front Mol Biosci 4:1–25. https://doi.org/10.3389/fmolb.2017.00019
Falker C, Hartmann A, Guett I et al (2016) Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity. J Neurochem 137:88–100. https://doi.org/10.1111/jnc.13514
CAS Article PubMed Google Scholar
Leblanc P, Arellano-Anaya ZE, Bernard E et al (2017) Isolation of exosomes and microvesicles from cell culture systems to study prion transmission. In: Methods in Mol Biol 153–176
Adle-Biassette H, Verney C, Peoc’h K, et al (2006) Immunohistochemical expression of prion protein (PrPC) in the human forebrain during development. J Neuropathol Exp Neurol 65:698–706. https://doi.org/10.1097/01.jnen.0000228137.10531.72
CAS Article PubMed Google Scholar
Linden R, Martins VR, Prado MAM et al (2008) Physiology of the prion protein. Physiol Rev 88:673–728. https://doi.org/10.1152/physrev.00007.2007
CAS Article PubMed Google Scholar
Moser M, Colello RJ, Pott U, Oesch B (1995) Developmental expression of the prion protein gene in glial cells. Neuron 14:509–517. https://doi.org/10.1016/0896-6273(95)90307-0
CAS Article PubMed Google Scholar
Watts JC, Bourkas MEC, Arshad H (2018) The function of the cellular prion protein in health and disease. Acta Neuropathol 135:159–178. https://doi.org/10.1007/s00401-017-1790-y
CAS Article PubMed Google Scholar
Arantes C, Nomizo R, Lopes MH et al (2009) Prion protein and its ligand stress inducible protein 1 regulate astrocyte development. Glia 57:1439–1449. https://doi.org/10.1002/glia.20861
Hartmann CA, Martins VR, Lima FRS (2013) High levels of cellular prion protein improve astrocyte development. FEBS Lett 587:238–244. https://doi.org/10.1016/j.febslet.2012.11.032
CAS Article PubMed Google Scholar
Lima FRS, Arantes CP, Muras AG et al (2007) Cellular prion protein expression in astrocytes modulates neuronal survival and differentiation. J Neurochem 103:2164–2176. https://doi.org/10.1111/j.1471-4159.2007.04904.x
CAS Article PubMed Google Scholar
Chadi S, Young R, Le Guillou S et al (2010) Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse. BMC Genomics 11:448. https://doi.org/10.1186/1471-2164-11-448
CAS Article PubMed PubMed Central Google Scholar
Halliez S, Passet B, Martin-Lannerée S, et al (2014) To develop with or without the prion protein. Front Cell Dev Biol 2:1–10. https://doi.org/10.3389/fcell.2014.00058
Weissmann C, Flechsig E (2003) PrP knock-out and PrP transgenic mice in prion research. Br Med Bull 66:43–60. https://doi.org/10.1093/bmb/66.1.43
CAS Article PubMed Google Scholar
Mallucci GR (2002) Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration. EMBO J 21:202–210. https://doi.org/10.1093/emboj/21.3.202
CAS Article PubMed PubMed Central Google Scholar
Manson JC, Clarke AR, Hooper ML et al (1994) 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol Neurobiol 8:121–127. https://doi.org/10.1007/BF02780662
CAS Article PubMed Google Scholar
Richt JA, Kasinathan P, Hamir AN et al (2007) Production of cattle lacking prion protein. Nat Biotechnol 25:132–138. https://doi.org/10.1038/nbt1271
CAS Article PubMed Google Scholar
White MD, Farmer M, Mirabile I et al (2008) Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease. Proc Natl Acad Sci U S A 105:10238–10243. https://doi.org/10.1073/pnas.0802759105
Article PubMed PubMed Central Google Scholar
Yu G, Chen J, Xu Y et al (2009) Generation of goats lacking prion protein. Mol Reprod Dev 76:3
Büeler H, Fischer M, Lang Y et al (1992) Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356:577–582. https://doi.org/10.1038/356577a0
Gerlai R (1996) Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci 19:177–181. https://doi.org/10.1016/S0166-2236(96)20020-7
CAS Article PubMed Google Scholar
Nuvolone M, Hermann M, Sorce S et al (2016) Strictly co-isogenic C57BL/6J-Prnp-/- mice: a rigorous resource for prion science. J Exp Med 213:313–327. https://doi.org/10.1084/jem.20151610
CAS Article PubMed PubMed Central Google Scholar
Norrby E (2011) Prions and protein-folding diseases. J Intern Med 270:1–14
Prusiner SB, Scott MR, DeArmond SJ, Cohen FE (1998) Prion protein biology. Cell 93:337–348
Cox TO, Gunther EC, Brody AH et al (2019) Anti-PrPC antibody rescues cognition and synapses in transgenic alzheimer mice. Ann Clin Transl Neurol 6:554–574. https://doi.org/10.1002/acn3.730
CAS Article PubMed PubMed Central Google Scholar
Linden R (2017) The biological function of the prion protein: a cell surface scaffold of signaling modules. Front Mol Neurosci 10:1–19. https://doi.org/10.3389/fnmol.2017.00077
Pan Y, Zhao L, Liang J et al (2006) Cellular prion protein promotes invasion and metastasis of gastric cancer. FASEB J 20:1886–1888. https://doi.org/10.1096/fj.06-6138fje
CAS Article PubMed Google Scholar
Wang Y, Yu S, Huang D et al (2016) Cellular prion protein mediates pancreatic cancer cell survival and invasion through association with and enhanced signaling of Notch1. Am J Pathol 186:2945–2956. https://doi.org/10.1016/j.ajpath.2016.07.010
CAS Article PubMed PubMed Central Google Scholar
Yang X, Zhang Y, Zhang L et al (2014) Prion protein and cancers. Acta Biochim Biophys Sin (Shanghai) 46:431–440. https://doi.org/10.1093/abbs/gmu019
Zhou L, Shang Y, Liu C et al (2014) Overexpression of PrPc, combined with MGr1-Ag/37LRP, is predictive of poor prognosis in gastric cancer. Int J Cancer 135:2329–2337. https://doi.org/10.1002/ijc.28883
CAS Article PubMed PubMed Central Google Scholar
Cashman NR, Loertscher R, Nalbantoglu J et al (1990) Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell 61:185–192. https://doi.org/10.1016/0092-8674(90)90225-4
CAS Article PubMed Google Scholar
Isaacs JD, Jackson GS, Altmann DM (2006) The role of the cellular prion protein in the immune system. Clin Exp Immunol 146:1–8. https://doi.org/10.1111/j.1365-2249.2006.03194.x
CAS Article PubMed PubMed Central Google Scholar
Esiri MM, Carter J, Ironside JW (2000) Prion protein immunoreactivity in brain samples from an unselected autopsy population: findings in 200 consecutive cases. Neuropathol Appl Neurobiol 26:273–284. https://doi.org/10.1046/j.1365-2990.2000.00239.x
CAS Article PubMed Google Scholar
Harris DA, Lele P, Snider WD (1993) Localization of the mRNA for a chicken prion protein by in situ hybridization. Proc Natl Acad Sci U S A 90:4309–4313. https://doi.org/10.1073/pnas.90.9.4309
CAS Article PubMed PubMed Central Google Scholar
McLennan NF, Rennison KA, Bell JE, Ironside JW (2001) In situ hybridization analysis of PrP mRNA in human CNS tissues. Neuropathol Appl Neurobiol 27:373–383. https://doi.org/10.1046/j.0305-1846.2001.00343.x
CAS Article PubMed Google Scholar
Tremblay P, Bouzamondo-Bernstein E, Heinrich C et al (2007) Developmental expression of PrP in the post-implantation embryo. Brain Res 1139:60–67. https://doi.org/10.1016/j.brainres.2006.12.055
CAS Article PubMed Google Scholar
Bendheim PE, Brown HR, Rudelli RD et al (1992) Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology 42:149–156. https://doi.org/10.1212/wnl.42.1.149
CAS Article PubMed Google Scholar
Manson J, West JD, Thomson V et al (1992) The prion protein gene: a role in mouse embryogenesis? Development 115:117–122. https://doi.org/10.1242/dev.115.1.117
CAS Article PubMed Google Scholar
Peralta OA, Huckle WR, Eyestone WH (2011) Expression and knockdown of cellular prion protein (PrPC) in differentiating mouse embryonic stem cells. Differentiation 81:68–77. https://doi.org/10.1016/j.diff.2010.09.181
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