Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1

Sivakova N, Lipatova L, Serebryanaya N. 1.009 - the role of neuroinflammation in pathogenesis of epilepsy and the possibility of neuroimmunomodulation. Eur Neuropsychopharmacol. 2018;28:S9–10.

Article  Google Scholar 

Liang W, Wang J, Sui J, Yun F, Shen Y, Zhou J, Wu Y, Shen D, Zhang Q. Inflammation as a target for the treatment of fever-associated epilepsy in zebrafish larvae. Int Immunopharmacol. 2023;116:109802.

Article  CAS  PubMed  Google Scholar 

Atabaki R, Khaleghzadeh-Ahangar H, Esmaeili N, Mohseni-Moghaddam P. Role of Pyroptosis, a pro-inflammatory programmed cell death, in Epilepsy. Cell Mol Neurobiol. 2023;43(3):1049–59.

Article  CAS  PubMed  Google Scholar 

Koepp MJ, Årstad E, Bankstahl JP, Dedeurwaerdere S, Friedman A, Potschka H, Ravizza T, Theodore WH, Baram TZ. Neuroinflammation imaging markers for epileptogenesis. Epilepsia. 2017;58(S3):11–9.

Article  PubMed  Google Scholar 

Brennan GP, Garcia-Curran MM, Patterson KP, Luo R, Baram TZ. Multiple disruptions of Glial-Neuronal Networks in Epileptogenesis that follows prolonged Febrile seizures. Front Neurol 12 (2021).

Jin W-N, Shi SX-Y, Li Z, Li M, Wood K, Gonzales RJ, Liu Q. Depletion of microglia exacerbates postischemic inflammation and brain injury. J Cereb Blood Flow Metabolism. 2017;37(6):2224–36.

Article  CAS  Google Scholar 

Lu Y, Xu X, Jiang T, Jin L, Zhao X-D, Cheng J-H, Jin X-J, Ma J, Piao H-N, Piao L-X. Sertraline ameliorates inflammation in CUMS mice and inhibits TNF-α-induced inflammation in microglia cells. Int Immunopharmacol. 2019;67:119–28.

Article  CAS  PubMed  Google Scholar 

Patel DC, Tewari BP, Chaunsali L, Sontheimer H. Neuron–glia interactions in the pathophysiology of epilepsy. Nat Rev Neurosci. 2019;20(5):282–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fujikawa R, Higuchi S, Nakatsuji M, Yasui M, Ikedo T, Nagata M, Yokode M, Minami M. EP4 Receptor−Associated Protein in Microglia Promotes Inflammation in the Brain. American J Path. 2016;186(8):1982–1988.

Pavlíková N. Caffeic Acid and Diseases—Mechanisms of Action, Int J Mole Sci. 2023;24(1):588.

Wang Y, Wang Y, Li J, Hua L, Han B, Zhang Y, Yang X, Zeng Z, Bai H, Yin H, Lou J. Effects of caffeic acid on learning deficits in a model of Alzheimer’s disease. Int J Mol Med. 2016;38(3):869–75.

Article  CAS  PubMed  Google Scholar 

Wu G, Cheng B, Qian H, Ma S, Chen Q. Identification of HSP90 as a direct target of artemisinin for its anti-inflammatory activity via quantitative chemical proteomics. Org Biomol Chem. 2019;17(28):6854–9.

Article  CAS  PubMed  Google Scholar 

Gao P, Wang J, Chen J, Gu L, Wang C, Xu L, Kwan Wong Y, Zhang H, Xu C, Dai L, Wang J. Profiling the Antimalarial Mechanism of Artemisinin by Identifying Crucial Target Proteins, Engineering (2023).

Luo P, Liu D, Zhang Q, Yang F, Wong Y-K, Xia F, Zhang J, Chen J, Tian Y, Yang C, Dai L, Shen H-M, Wang J. Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1. Acta Pharm Sinica B. 2022;12(5):2300–14.

Article  CAS  Google Scholar 

Yang T, Liu D, Li Y, Zhang Y, Zhu Y, Zhang J, Wang C, Zhang S, Wong YK, Luo P, Guo Q, Xia F, Zhong T, Tang H, Wang J. Chemoproteomics reveals Sofalcone inhibits the inflammatory response of Caco-2 cells by covalently targeting HMGB1. Chem Commun (Camb). 2023;59(58):8981–4.

Article  CAS  PubMed  Google Scholar 

Schofield JH, Hawk MA, Rahmy S, Sheldon RD, Leimbach C, Sun S, Lu X, Jones RG, Schafer ZT. Abstract 2331: metabolic evasion of mCRPC immunotherapy by ACOD1 production of itaconate. Cancer Res. 2021;81(13Supplement):2331–2331.

Article  Google Scholar 

Perez LC, De lV, Sahini LN, Czichon L, Zobl W, Zillinger T, Shehata M, Pleschka S, Baehre H, Falk C. Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism. Nat Metabolism (4–5) (2022).

Wu R, Liu J, Tang D, Kang R. The dual role of ACOD1 in inflammation. J Immunol. 2023;211(4):518–26.

Article  CAS  PubMed  Google Scholar 

Kokras N, Dalla C. Sex differences in animal models of psychiatric disorders. Br J Pharmacol. 2014;171(20):4595–619.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yagi S, Galea LAM. Sex differences in hippocampal cognition and neurogenesis. Neuropsychopharmacology. 2019;44(1):200–13.

Article  PubMed  Google Scholar 

Li G, Liu X, Sun X, Huang L, Kuang W, Ou J, Zhang J, Zhang Z, Li H, Tang H, Feng C, Gu L, Yang C, Peili W, Wang J. Polystyrene microplastics induce anxiety via HRAS derived PERK-NF-κB pathway. Environ Int. 2024;185:108543.

Article  CAS  PubMed  Google Scholar 

Wang J, Zhang C-J, Chia WN, Loh CCY, Li Z, Lee YM, He Y, Yuan L-X, Lim TK, Liu M, Liew CX, Lee YQ, Zhang J, Lu N, Lim CT, Hua Z-C, Liu B, Shen H-M, Tan KSW, Lin Q. Haem-activated promiscuous targeting of artemisinin in Plasmodium Falciparum. Nat Commun. 2015;6(1):10111.

Article  CAS  PubMed  Google Scholar 

Jensen EC. Quantitative analysis of histological staining and fluorescence using ImageJ. Anat Rec. 2013;296(3):378–81.

Article  Google Scholar 

Ma N, Hu J, Zhang ZM, Liu W, Huang M, Fan Y, Yin X, Wang J, Ding K. Ye, 2H-Azirine-based reagents for Chemoselective Bioconjugation at Carboxyl residues inside live cells. J Am Chem Soc. 2020;13:142.

Google Scholar 

Liu LP, Gu DD, Zhang L, Gao Q, Zhu P. Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion. J Neuroinflamm. 2021;18(1):174.

Article  CAS  Google Scholar 

Barri T, Dragsted LO. UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: Effect of experimental artefacts and anticoagulant. Anal Chim Acta. 2013;768:118–28.

Article  CAS  PubMed  Google Scholar 

Want EJ, Masson P, Michopoulos F, Wilson ID, Theodoridis G, Plumb RS, Shockcor J, Loftus N, Holmes E, Nicholson JK. Global metabolic profiling of animal and human tissues via UPLC-MS. Nat Protoc. 2013;8(1):17–32.

Article  CAS  PubMed  Google Scholar 

Sha L, Li G, Zhang X, Lin Y, Qiu Y, Deng Y, Zhu W, Xu Q. Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice. JCI Insight 7(15) (2022).

Hengst JA, Dick TE, Smith CD, Yun JK. Analysis of selective target engagement by small-molecule sphingosine kinase inhibitors using the Cellular Thermal Shift Assay (CETSA).

Trott O, Olson AJ. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem. 2010;31(2):455–61.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qiu Y, Sha L, Zhang X, Li G, Zhu W, Xu Q. Induction of a disintegrin and metalloproteinase with thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer’s disease risk. Front Aging Neurosci 14 (2022).

Diaz-Castro B, Bernstein AM, Coppola G, Sofroniew MV, Khakh BS. Molecular and functional properties of cortical astrocytes during peripherally induced neuroinflammation. Cell Rep. 2021;36(6):109508.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li X, Lin J, Hua Y, Gong J, Ding S, Du Y, Wang X, Zheng R, Xu H. Agmatine alleviates epileptic seizures and hippocampal neuronal damage by inhibiting gasdermin D-Mediated pyroptosis. Front Pharmacol 12 (2021).

Xiao T, Wan J, Qu H, Li Y. Tripartite-motif protein 21 knockdown extenuates LPS-triggered neurotoxicity by inhibiting microglial M1 polarization via suppressing NF-κB-mediated NLRP3 inflammasome activation. Arch Biochem Biophys. 2021;706:108918.

Article  CAS  PubMed  Google Scholar 

Zhao Y, Zhang J, Zheng Y, Zhang Y, Zhang XJ, Wang H, Du Y, Guan J, Wang X, Fu J. NAD + improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. J Neuroinflamm. 2021;18(1):207.

Article  CAS  Google Scholar 

Gao Y, Tu D, Yang R, Chu C-H, Hong J-S, Gao H-M. Through reducing ROS Production, IL-10 suppresses Caspase-1-Dependent IL-1β maturation, thereby preventing chronic neuroinflammation and neurodegeneration. Int J Mol Sci. 2020;21(2):465.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu R, Chen F, Wang N, Tang D, Kang R. ACOD1 in immunometabolism and disease. Cell Mol Immunol. 2020;17(8):822–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu DD, Luo P, Gu L, Zhang Q, Gao P, Zhu Y, Chen X, Guo Q, Zhang J, Ma N, Wang J. Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion. J Neuroinflammation. 2021;18(1):174.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang J, Zhang CJ, Chia WN, Loh CCY, Li Z, Lee YM, He Y, Yuan LX, Lim TK, Liu M. Haem-activated promiscuous targeting of artemisinin in. Nat Commun. 2015;6:10111.

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