Nanoscopy reveals integrin clustering reliant on kindlin-3 but not talin-1

Liew PX, Kubes P. The Neutrophil’s role during Health and Disease. Physiol Rev. 2019;99:1223–48.

Article  PubMed  CAS  Google Scholar 

Mayadas TN, Cullere X, Lowell CA. The multifaceted functions of neutrophils. Annu Rev Pathol. 2014;9:181–218.

Article  PubMed  CAS  Google Scholar 

Gronloh MLB, Tebbens ME, Kotsi M, Arts JJG, van Buul JD. Intercellular adhesion molecule 2 regulates diapedesis hotspots by allowing neutrophil crawling against the direction of flow. Vasc Biol. 2023;5(1):e230005.

Papayannopoulos V. Neutrophil extracellular traps in immunity and disease. Nat Rev Immunol. 2018;18:134–47.

Article  PubMed  CAS  Google Scholar 

Tecchio C, Cassatella MA. Uncovering the multifaceted roles played by neutrophils in allogeneic hematopoietic stem cell transplantation. Cell Mol Immunol. 2021;18:905–18.

Article  PubMed  CAS  Google Scholar 

Kolaczkowska E, Kubes P. Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol. 2013;13:159–75.

Article  PubMed  CAS  Google Scholar 

Wang K, et al. Locally organised and activated Fth1(hi) neutrophils aggravate inflammation of acute lung injury in an IL-10-dependent manner. Nat Commun. 2022;13:7703.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Marin-Prida J, et al. The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and modulation of the neuronal proteome. Front Immunol. 2023;14:1227268.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Jin L, et al. Low-dose ethanol consumption inhibits neutrophil extracellular traps formation to alleviate rheumatoid arthritis. Commun Biol. 2023;6:1088.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Nouri M, Westrom B, Lavasani S. Elevated fecal calprotectin accompanied by intestinal neutrophil infiltration and Goblet Cell Hyperplasia in a murine model of multiple sclerosis. Int J Mol Sci. 2023;24(20):15367.

McGinley AM, et al. Interleukin-17A serves a priming role in autoimmunity by recruiting IL-1beta-Producing myeloid cells that promote pathogenic T cells. Immunity. 2020;52:342–e356346.

Article  PubMed  CAS  Google Scholar 

Zhou HY et al. Recent advances in the involvement of epigenetics in the pathogenesis of systemic lupus erythematosus. Clin Immunol. 2023;258: 109857.

Phillipson M, Kubes P. The neutrophil in vascular inflammation. Nat Med. 2011;17:1381–90.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sadik CD, Kim ND, Luster AD. Neutrophils cascading their way to inflammation. Trends Immunol. 2011;32:452–60.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ley K et al. Neutrophils: New insights and open questions. Sci Immunol. 2018;3(30):eaat4579.

Bader A, et al. Molecular insights into Neutrophil Biology from the zebrafish perspective: lessons from CD18 Deficiency. Front Immunol. 2021;12:677994.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yago T, Zhang N, Zhao L, Abrams CS, McEver RP. Selectins and chemokines use shared and distinct signals to activate beta2 integrins in neutrophils. Blood Adv. 2018;2:731–44.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kuwano Y, Spelten O, Zhang H, Ley K, Zarbock A. Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils. Blood. 2010;116:617–24.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Fan Z, et al. Neutrophil recruitment limited by high-affinity bent beta2 integrin binding ligand in cis. Nat Commun. 2016;7:12658.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Lawrence MB, Springer TA. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell. 1991;65:859–73.

Article  PubMed  CAS  Google Scholar 

DiVietro JA, et al. Immobilized IL-8 triggers progressive activation of neutrophils rolling in vitro on P-selectin and intercellular adhesion molecule-1. J Immunol. 2001;167:4017–25.

Article  PubMed  CAS  Google Scholar 

Wang Y, et al. The role of G protein-coupled receptor in neutrophil dysfunction during sepsis-induced acute respiratory distress syndrome. Front Immunol. 2023;14:1112196.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wen L, Moser M, Ley K. Molecular mechanisms of leukocyte beta2 integrin activation. Blood. 2022;139:3480–92.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bromberger T, et al. Binding of Rap1 and Riam to Talin1 Fine-Tune beta2 integrin activity during leukocyte trafficking. Front Immunol. 2021;12:702345.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ni N, Kevil CG, Bullard DC, Kucik DF. Avidity modulation activates adhesion under flow and requires cooperativity among adhesion receptors. Biophys J. 2003;85:4122–33.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Stewart M, Hogg N. Regulation of leukocyte integrin function: affinity vs. avidity. J Cell Biochem. 1996;61:554–61.

Article  PubMed  CAS  Google Scholar 

Changede R, Sheetz M. Integrin and cadherin clusters: a robust way to organize adhesions for cell mechanics. BioEssays. 2017;39:1–12.

Article  PubMed  CAS  Google Scholar 

van Kooyk Y, Figdor CG. Avidity regulation of integrins: the driving force in leukocyte adhesion. Curr Opin Cell Biol. 2000;12:542–7.

Article  PubMed  Google Scholar 

Luo BH, Carman CV, Springer TA. Structural basis of integrin regulation and signaling. Annu Rev Immunol. 2007;25:619–47.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Alon R, Feigelson SW. Chemokine-triggered leukocyte arrest: force-regulated bi-directional integrin activation in quantal adhesive contacts. Curr Opin Cell Biol. 2012;24:670–6.

Article  PubMed  CAS  Google Scholar 

Ley K, Laudanna C, Cybulsky MI, Nourshargh S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol. 2007;7:678–89.

Article  PubMed  CAS  Google Scholar 

Fan Z, et al. High-Affinity Bent beta(2)-Integrin molecules in arresting neutrophils face each other through binding to ICAMs in cis. Cell Rep. 2019;26:119–e130115.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Lefort CT, Ley K. Neutrophil arrest by LFA-1 activation. Front Immunol. 2012;3:157.

Article  PubMed  PubMed Central 

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