A cutting-edge investigation of the multifaceted role of SOX family genes in cancer pathogenesis through the modulation of various signaling pathways

Adikusuma F, Pederick D, McAninch D, Hughes J, Thomas P (2017) Functional equivalence of the SOX2 and SOX3 transcription factors in the developing mouse brain and testes. Genetics 206:1495–1503. https://doi.org/10.1534/genetics.117.202549

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aghajanian P, Mohan S (2018) The art of building bone: emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification. Bone Res 6:19

Article  PubMed  PubMed Central  Google Scholar 

Amer S, Ibrahim H, Elkordy M (2022) The immunohistochemical expression of SOX-10 in Urothelial Carcinoma and the non neoplastic urothelium; and a correlation with the Tumor features. Asian Pac J Cancer Prev 23:1425–1432

Article  CAS  PubMed  PubMed Central  Google Scholar 

Annovazzi L, Mellai M, Caldera V, Valente G, Schiffer D (2011) SOX2 expression and amplification in gliomas and glioma cell lines. Cancer Genomics Proteom 8:139–147

CAS  Google Scholar 

Aoki Y, Saint-Germain N, Gyda M, Magner-Fink E, Lee YH, Credidio C, Saint-Jeannet JP (2003) Sox10 regulates the development of neural crest-derived melanocytes in Xenopus. Dev Biol 259:19–33. https://doi.org/10.1016/s0012-1606(03)00161-1

Article  CAS  PubMed  Google Scholar 

Ashrafizadeh M, Taeb S, Hushmandi K, Orouei S, Shahinozzaman M, Zabolian A, Moghadam ER, Raei M, Zarrabi A, Khan H, Najafi M (2020) Cancer and SOX proteins: New insight into their role in ovarian cancer progression/inhibition. Pharmacol Res 161:105159. https://doi.org/10.1016/j.phrs.2020.105159

Article  CAS  PubMed  Google Scholar 

Bagati A, Kumar S, Jiang P, Pyrdol J, Zou AE, Godicelj A, Mathewson ND, Cartwright ANR, Cejas P, Brown M, Giobbie-Hurder A, Dillon D, Agudo J, Mittendorf EA, Liu XS, Wucherpfennig KW (2021) Integrin αvβ6-TGFβ-SOX4 pathway drives Immune Evasion in Triple-negative breast Cancer. Cancer Cell 39:54–67e59. https://doi.org/10.1016/j.ccell.2020.12.001

Article  CAS  PubMed  Google Scholar 

Bahmad HF, Thiravialingam A, Sriganeshan K, Gonzalez J, Alvarez V, Ocejo S, Abreu AR, Avellan R, Arzola AH, Hachem S (2023a) Clinical significance of SOX10 expression in Human Pathology. Curr Issues Mol Biol 45:10131–10158

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bahmad HF, Thiravialingam A, Sriganeshan K, Gonzalez J, Alvarez V, Ocejo S, Abreu AR, Avellan R, Arzola AH, Hachem S, Poppiti R (2023b) Clinical significance of SOX10 expression in Human Pathology. Curr Issues Mol Biol 45:10131–10158. https://doi.org/10.3390/cimb45120633

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baroni T, Arato I, Mancuso F, Calafiore R, Luca G (2019) On the origin of testicular germ cell tumors: from gonocytes to testicular cancer. Front Endocrinol 10:343

Article  Google Scholar 

Bi Q, Wu JY, Qiu XM, Zhang JD, Sun ZJ, Wang W (2022) Tumor-associated inflammation: the tumor-promoting immunity in the early stages of tumorigenesis. J Immunol Res 2022:3128933. https://doi.org/10.1155/2022/3128933

Blobel GA (2002) CBP and p300: versatile coregulators with important roles in hematopoietic gene expression. J Leukoc Biol 71:545–556

Article  CAS  PubMed  Google Scholar 

Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Lefebvre PP, Malgrange B (2009) Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti. Dev Biol 335:327–339. https://doi.org/10.1016/j.ydbio.2009.09.007

Article  CAS  PubMed  Google Scholar 

Castillo SD, Sanchez-Cespedes M (2012) The SOX family of genes in cancer development: biological relevance and opportunities for therapy. Expert Opin Ther Targets 16:903–919

Article  CAS  PubMed  Google Scholar 

Chakravarty G, Moroz K, Makridakis NM, Lloyd SA, Galvez SE, Canavello PR, Lacey MR, Agrawal K, Mondal D (2011) Prognostic significance of cytoplasmic SOX9 in invasive ductal carcinoma and metastatic breast cancer. Experimental Biology Med (Maywood NJ) 236:145–155. https://doi.org/10.1258/ebm.2010.010086

Article  CAS  Google Scholar 

Chang S-Y, Wu T-H, Shih Y-L, Chen Y-C, Su H-Y, Chian C-F, Lin Y-W (2023) SOX1 functions as a Tumor suppressor by repressing HES1 in Lung Cancer. Cancers 15:2207

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chaves-Moreira D, Mitchell MA, Arruza C, Rawat P, Sidoli S, Nameki R, Reddy J, Corona RI, Afeyan LK, Klein IA (2022) The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17. Sci Signal 15:eabm2496

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheung M, Tai A, Lu PJ, Cheah KS (2019) Acquisition of multipotent and migratory neural crest cells in vertebrate evolution. Curr Opin Genet Dev 57:84–90. https://doi.org/10.1016/j.gde.2019.07.018

Article  CAS  PubMed  Google Scholar 

Chiurillo MA (2015) Role of the Wnt/β-catenin pathway in gastric cancer: an in-depth literature review. World J Experimental Med 5:84

Article  Google Scholar 

Costa JJ, Souza GB, Soares MA, Ribeiro RP, van den Hurk R, Silva JR (2018) In vitro differentiation of primordial germ cells and oocyte-like cells from stem cells

Cui J, Xi H, Cai A, Bian S, Wei B, Chen L (2014) Decreased expression of Sox7 correlates with the upregulation of the Wnt/β-catenin signaling pathway and the poor survival of gastric cancer patients. Int J Mol Med 34:197–204

Article  CAS  PubMed  Google Scholar 

Cui K, Zhang H, Wang G (2019) MiR-483 suppresses cell proliferation and promotes cell apoptosis by targeting SOX3 in breast cancer. Eur Rev Med Pharmacol Sci 23:2069–2074

CAS  PubMed  Google Scholar 

de la Rocha AM, Sampron N, Alonso MM, Matheu A (2014) Role of SOX family of transcription factors in central nervous system tumors. Am J cancer Res 4:312–324

PubMed  PubMed Central  Google Scholar 

Deng X, Wang Y, Guo H, Wang Q, Rao S, Wu H (2023) Pan-cancer analysis and experimental validation of SOX4 as a potential diagnosis, prognosis, and immunotherapy biomarker. Cancers (Basel) 15. https://doi.org/10.3390/cancers15215235

Dey A, Kundu M, Das S, Jena BC, Mandal M (2022) Understanding the function and regulation of Sox2 for its therapeutic potential in breast cancer. Biochim et Biophys Acta (BBA)-Reviews Cancer 1877:188692

Article  CAS  Google Scholar 

Earley AM (2021) The role of Basic Helix Loop Helix transcription factors in regulating neural cell decisions from human pluripotent stem cells. Northwestern University

Elbaz B, Popko B (2019) Molecular Control of Oligodendrocyte Development. Trends Neurosci 42:263–277. https://doi.org/10.1016/j.tins.2019.01.002

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng W, Liu S, Zhu R, Li B, Zhu Z, Yang J, Song C (2017) SOX10 induced nestin expression regulates cancer stem cell properties of TNBC cells. Biochem Biophys Res Commun 485:522–528

Article  CAS  PubMed  Google Scholar 

Ferletta M, Caglayan D, Mokvist L, Jiang Y, Kastemar M, Uhrbom L, Westermark B (2011) Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells. Int J Cancer 129:45–60. https://doi.org/10.1002/ijc.25647

Article  CAS  PubMed  Google Scholar 

Finzsch M, Stolt CC, Lommes P, Wegner M (2008) Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Development 135:637–646. https://doi.org/10.1242/dev.010454

Article  CAS  PubMed  Google Scholar 

Fu D-Y, Wang Z-M, Wang B-L, Shen Z-Z, Huang W, Shao Z-M (2010a) Sox17, the canonical wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer. Breast Cancer Res Treat 119:601–612

Article  CAS  PubMed  Google Scholar 

Fu DY, Wang ZM, Li C, Wang BL, Shen ZZ, Huang W, Shao ZM (2010b) Sox17, the canonical wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer. Breast Cancer Res Treat 119:601–612. https://doi.org/10.1007/s10549-009-0339-8

Article  CAS  PubMed  Google Scholar 

Fu D, Ren C, Tan H, Wei J, Zhu Y, He C, Shao W, Zhang J (2015a) Sox17 promoter methylation in plasma DNA is associated with poor survival and can be used as a prognostic factor in breast cancer. Medicine 94:e637. https://doi.org/10.1097/md.0000000000000637

Article 

留言 (0)

沒有登入
gif