Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, Claeys MJ, Dan GA, Dweck MR, Galbraith M, et al. 2023 ESC guidelines for the management of acute coronary syndromes. Eur Heart J Acute Cardiovasc care. 2024;13(1):55–161.

Article  PubMed  Google Scholar 

Wei QC, Chen YW, Gao QY, Ren KD, Liu YB, He F, Shi JT, Jiang J. Association of stress hyperglycemia with clinical outcomes in patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention: a cohort study. Cardiovasc Diabetol. 2023;22(1):85.

Article  PubMed  PubMed Central  Google Scholar 

Henning RJ. Type-2 diabetes mellitus and cardiovascular disease. Future Cardiol. 2018;14(6):491–509.

Article  PubMed  Google Scholar 

Jonas M, Kagan M, Sella G, Haberman D, Chernin G. Cardiovascular outcomes following percutaneous coronary intervention with drug-eluting balloons in chronic kidney disease: a retrospective analysis. BMC Nephrol. 2020;21(1):445.

Article  PubMed  PubMed Central  Google Scholar 

Benn M, Tybjaerg-Hansen A, McCarthy MI, Jensen GB, Grande P, Nordestgaard BG. Nonfasting glucose, ischemic heart disease, and myocardial infarction: a mendelian randomization study. J Am Coll Cardiol. 2012;59(25):2356–65.

Article  PubMed  PubMed Central  Google Scholar 

Ding D, Qiu J, Li X, Li D, Xia M, Li Z, Su D, Wang Y, Zhang Y, Zhang J, et al. Hyperglycemia and mortality among patients with coronary artery disease. Diabetes Care. 2014;37(2):546–54.

Article  PubMed  Google Scholar 

Marfella R, Sasso FC, Siniscalchi M, Paolisso P, Rizzo MR, Ferraro F, Stabile E, Sorropago G, Calabrò P, Carbonara O, Cinquegrana G, Piscione F, Ruocco A, D’Andrea D, Rapacciuolo A, Petronella P, Bresciani A, Rubino P, Mauro C, Paolisso G. Peri-procedural tight glycemic control during early percutaneous coronary intervention is associated with a lower rate of in-stent restenosis in patients with acute ST-elevation myocardial infarction. J Clin Endocrinol Metab. 2012;97(8):2862–71.

Balestrieri ML, Servillo L, Esposito A, D’Onofrio N, Giovane A, Casale R, Barbieri M, Paolisso P, Rizzo MR, Paolisso G, Marfella R. Poor glycaemic control in type 2 diabetes patients reduces endothelial progenitor cell number by influencing SIRT1 signalling via platelet-activating factor receptor activation. Diabetologia. 2013;56(1):162–72.

Article  PubMed  Google Scholar 

Yang J, Zheng Y, Li C, Gao J, Meng X, Zhang K, Wang W, Shao C, Tang YD. The impact of the stress hyperglycemia ratio on short-term and long-term poor prognosis in patients with Acute Coronary Syndrome: insight from a large cohort study in Asia. Diabetes Care. 2022;45(4):947–56.

Article  PubMed  Google Scholar 

Gao S, Huang S, Lin X, Xu L, Yu M. Prognostic implications of stress hyperglycemia ratio in patients with myocardial infarction with nonobstructive coronary arteries. Ann Med. 2023;55(1):990–9.

Article  PubMed  PubMed Central  Google Scholar 

Schmitz T, Freuer D, Harmel E, Heier M, Peters A, Linseisen J, Meisinger C. Prognostic value of stress hyperglycemia ratio on short- and long-term mortality after acute myocardial infarction. Acta Diabetol. 2022;59(8):1019–29.

Article  PubMed  PubMed Central  Google Scholar 

Zeng G, Song Y, Zhang Z, Xu J, Liu Z, Tang X, Wang X, Chen Y, Zhang Y, Zhu P, et al. Stress hyperglycemia ratio and long-term prognosis in patients with acute coronary syndrome: a multicenter, nationwide study. J Diabetes. 2023;15(7):557–68.

Article  PubMed  PubMed Central  Google Scholar 

Xu W, Yang YM, Zhu J, Wu S, Wang J, Zhang H, Shao XH. Predictive value of the stress hyperglycemia ratio in patients with acute ST-segment elevation myocardial infarction: insights from a multi-center observational study. Cardiovasc Diabetol. 2022;21(1):48.

Article  PubMed  PubMed Central  Google Scholar 

Wang J, Yue X, Meng C, Wang Z, Jin X, Cui X, Yang J, Shan C, Gao Z, Yang Y, et al. Acute Hyperglycemia May induce Renal Tubular Injury through Mitophagy Inhibition. Front Endocrinol (Lausanne). 2020;11:536213.

Article  PubMed  Google Scholar 

Chen SQ, Liu J, Zhou Y, Huang ZD, Xie Y, Huang HZ, Yan XM, Xie YY, Hao PF, Liang Y, et al. Sex differences in characteristics, treatments, and In-hospital outcomes of patients undergoing coronary angiography or intervention. Front Cardiovasc Med. 2022;9:878566.

Article  PubMed  PubMed Central  Google Scholar 

Nathan DM, Kuenen J, Borg R, Zheng H, Schoenfeld D, Heine RJ, A1c-Derived Average Glucose Study Group. Translating the A1C assay into estimated average glucose values. Diabetes Care. 2008;31(8):1473–8.

Article  PubMed  PubMed Central  Google Scholar 

Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, Kusek JW, Eggers P, Van Lente F, Greene T, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–12.

Nutritional anaemias. Report of a WHO scientific group. World Health Organ Tech Rep Ser. 1968;405:5–37.

Google Scholar 

Yao Y, Wang B, Geng T, Chen J, Chen W, Li L. The association between TyG and all-cause/non-cardiovascular mortality in general patients with type 2 diabetes mellitus is modified by age: results from the cohort study of NHANES 1999–2018. Cardiovasc Diabetol. 2024;23(1):43.

Article  PubMed  PubMed Central  Google Scholar 

Mone P, Lombardi A, Salemme L, Cioppa A, Popusoi G, Varzideh F, Pansini A, Jankauskas SS, Forzano I, Avvisato R, Wang X, Tesorio T, Santulli G. Stress hyperglycemia drives the risk of hospitalization for chest Pain in patients with ischemia and nonobstructive coronary arteries (INOCA). Diabetes Care. 2023;46(2):450–4.

Article  PubMed  Google Scholar 

Sia CH, Chan MH, Zheng H, et al. Optimal glucose, HbA1c, glucose-HbA1c ratio and stress-hyperglycaemia ratio cut-off values for predicting 1-year mortality in diabetic and non-diabetic acute myocardial infarction patients. Cardiovasc Diabetol. 2021;20(1):211.

Article  PubMed  PubMed Central  Google Scholar 

Abdu FA, Galip J, Qi P, Zhang W, Mohammed AQ, Liu L, Yin G, Mohammed AA, Mareai RM, Jiang R, Xu Y, Che W. Association of stress hyperglycemia ratio and poor long-term prognosis in patients with myocardial infarction with non-obstructive coronary arteries. Cardiovasc Diabetol. 2023;22(1):11.

Article  PubMed  PubMed Central  Google Scholar 

Marfella R, Sasso FC, Siniscalchi M, et al. Peri-procedural tight glycemic control during early percutaneous coronary intervention is associated with a lower rate of in-stent restenosis in patients with acute ST-elevation myocardial infarction. J Clin Endocrinol Metab. 2012;97(8):2862–71.

Article  PubMed  Google Scholar 

Xu W, Song Q, Wang X, Zhao Z, Meng X, Xia C, Xie Y, Yang C, Guo Y, Zhang Y, et al. Association of stress hyperglycemia ratio and in-hospital mortality in patients with coronary artery disease: insights from a large cohort study. Cardiovasc Diabetol. 2022;21(1):217.

Article  PubMed  PubMed Central  Google Scholar 

Liao W, Chen Y, Gao Q, Gan R, Li M, Liu Z, Liang J, Cui H, Ren K, Liu Y, et al. Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients. Cardiovasc Diabetol. 2023;22(1):334.

Article  PubMed  PubMed Central  Google Scholar 

Mi D, Li Z, Gu H, Jiang Y, Zhao X, Wang Y, Wang Y. Stress hyperglycemia is associated with in-hospital mortality in patients with diabetes and acute ischemic stroke. CNS Neurosci Ther. 2022;28(3):372–81.

Article  PubMed  PubMed Central  Google Scholar 

Zhou Y, Liu L, Huang H, Li N, He J, Yao H, Tang X, Chen X, Zhang S, Shi Q, et al. Stress hyperglycemia ratio and in-hospital prognosis in non-surgical patients with heart failure and type 2 diabetes. Cardiovasc Diabetol. 2022;21(1):290.

Article  PubMed  PubMed Central  Google Scholar 

Paolisso P, Bergamaschi L, Rambaldi P, Gatta G, Foà A, Angeli F, Fabrizio M, Casella G, Barbieri M, Galiè N, et al. Impact of admission hyperglycemia on heart failure events and mortality in patients with Takotsubo Syndrome at Long-Term Follow-up: data from HIGH-GLUCOTAKO investigators. Diabetes Care. 2021;44(9):2158–61.

Article  PubMed  Google Scholar 

Kondapalli L, Moslehi J, Bonaca MP. Inflammation begets inflammation: cancer and acute MI. Eur Heart J. 2020;41(23):2194–6.

Article  PubMed  Google Scholar 

Braunwald E. Diabetes, heart failure, and renal dysfunction: the vicious circles. Prog Cardiovasc Dis. 2019;62(4):298–302.

Article  PubMed  Google Scholar 

Thomas MC, Cooper ME, Zimmet P. Changing epidemiology of type 2 diabetes mellitus and associated chronic kidney disease. Nat Rev Nephrol. 2016;12(2):73–81.

Article  PubMed  Google Scholar 

Zareini B, Blanche P, D’Souza M, Elmegaard Malik M, Nørgaard CH, Selmer C, Gislason G, Kristensen SL, Køber L, Torp-Pedersen C, et al. Type 2 diabetes Mellitus and Impact of Heart failure on prognosis compared to other Cardiovascular diseases: a Nationwide Study. Circulation Cardiovasc Qual Outcomes. 2020;13(7):e006260.

Article  Google Scholar 

de Rekeneire N, Peila R, Ding J, Colbert LH, Visser M, Shorr RI, Kritchevsky SB, Kuller LH, Strotmeyer ES, Schwartz AV, Vellas B, Harris TB. Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition study. Diabetes Care. 2006;29(8):1902–8.

Article