Unveiling the role of lipopolysaccharide-related genes in diabetic retinopathy: identification of key biomarkers and immune infiltration analysis

Bai S, Cheng H, Li H, Bo P. 2024. Integrated bioinformatics analysis identifies autophagy-associated genes as candidate biomarkers and reveals the immune infiltration landscape in psoriasis. Autoimmunity. 57(1):2259137. eng.

Berkowitz BA, Roberts R, Luan H, Peysakhov J, Knoerzer DL, Connor JR, Hohman TC. Drug intervention can correct subnormal retinal oxygenation response in experimental diabetic retinopathy. Investig Ophthalmol Vis Sci. 2005;46(8):2954–60. eng.

Article  Google Scholar 

Bordalo Tonucci L, Dos Santos KM, De Luces Fortes Ferreira CL, Ribeiro SM, De Oliveira LL, Martino HS. Gut microbiota and probiotics: focus on diabetes mellitus. Crit Rev Food Sci Nutr. 2017;57(11):2296–309. eng.

Article  PubMed  Google Scholar 

Gomes JMG, Costa JA, Alfenas RCG. Metabolic endotoxemia and diabetes mellitus: a systematic review. Metab Clin Exp. 2017;68:133–44. eng.

Article  PubMed  Google Scholar 

Habieb MS, Dawood AA, Emara MM, Elhelbawy MG, Elhelbawy NG. 2020. The Human Genetic Variants CYP2J2 rs2280275 and EPHX2 rs751141 and Risk of Diabetic Nephropathy in Egyptian Type 2 Diabetic Patients. The application of clinical genetics. 13:165–178. eng.

Hänzelmann S, Castelo R, Guinney J. 2013. GSVA: gene set variation analysis for microarray and RNA-seq data. BMC bioinformatics. 14:7. eng.

Hu W, Feng P, Zhang M, Tian T, Wang S, Zhao B, Li Y, Wang S, Wu C. 2022. Endotoxins Induced ECM-Receptor Interaction Pathway Signal Effect on the Function of MUC2 in Caco2/HT29 Co-Culture Cells. Frontiers in immunology. 13:916933. eng.

Huang L, Chen C, Zhang G, Ju Y, Zhang J, Wang H, Li J. 2015. STK33 overexpression in hypopharyngeal squamous cell carcinoma: possible role in tumorigenesis. BMC cancer. 15:13. eng.

Jabbehdari S, Sallam AB. Gut microbiome and diabetic retinopathy. Eur J Ophthalmol. 2022;32(5):2494–7. eng.

Article  PubMed  Google Scholar 

Larsen PP, Féart C, Pais de Barros JP, Merle BMJ, Gayraud L, Delyfer MN, Korobelnik JF, Delcourt C. 2023. Association of Age-Related Macular Degeneration with a Blood Biomarker of Lipopolysaccharide, a Gut Bacterial Proinflammatory Toxin. Investigative ophthalmology & visual science. 64(14):47. eng.

Li G, Veenstra AA, Talahalli RR, Wang X, Gubitosi-Klug RA, Sheibani N, Kern TS. Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice. Diabetes. 2012;61(12):3294–303. eng.

Article  PubMed  PubMed Central  Google Scholar 

Li H, Liao T, Debowski AW, Tang H, Nilsson HO, Stubbs KA, Marshall BJ, Benghezal M. Lipopolysaccharide structure and biosynthesis in Helicobacter pylori. Helicobacter. 2016;21(6):445–61. eng.

Article  PubMed  Google Scholar 

Li J, Chen K, Li X, Zhang X, Zhang L, Yang Q, Xia Y, Xie C, Wang X, Tong J, et al. Mechanistic insights into the alterations and regulation of the AKT signaling pathway in diabetic retinopathy. Cell Death Discovery. 2023;9(1):418. eng.

Article  PubMed  PubMed Central  Google Scholar 

Liang L, Tan X, Zhou Q, Zhu Y, Tian Y, Yu H, Kijlstra A, Yang P. IL-1β triggered by peptidoglycan and lipopolysaccharide through TLR2/4 and ROS-NLRP3 inflammasome-dependent pathways is involved in ocular Behçet’s disease. Investig Ophthalmol Vis Sci. 2013;54(1):402–14. eng.

Article  Google Scholar 

Liu MS, Zhao H, Xu CX, Xie PB, Wang W, Yang YY, Lee WH, Jin Y, Zhou HQ. Clinical significance of EPHX2 deregulation in prostate cancer. Asian J Androl. 2021;23(1):109–15. eng.

Article  PubMed  Google Scholar 

Lu Y, Tang J, Zhang W, Shen C, Xu L, Yang D. Correlation between STK33 and the pathology and prognosis of lung cancer. Oncol Lett. 2017;14(4):4800–4. eng.

Article  PubMed  PubMed Central  Google Scholar 

McAleer JP, Vella AT. Understanding how lipopolysaccharide impacts CD4 T-cell immunity. Crit Rev Immunol. 2008;28(4):281–99. eng.

Article  PubMed  PubMed Central  Google Scholar 

McEligot AJ, Poynor V, Sharma R, Panangadan A. Logistic LASSO regression for dietary intakes and breast Cancer. Nutrients. 2020;12(9):eng.

Article  Google Scholar 

Moudgil T, Bains BK, Bandhu S, Kanda N. Preferred practice pattern of physicians regarding diabetic retinopathy in diabetes mellitus patients. Indian J Ophthalmol. 2021;69(11):3139–43. eng.

Article  PubMed  PubMed Central  Google Scholar 

Mujica AO, Hankeln T, Schmidt ER. A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3. Gene. 2001;280(1–2):175–81. eng.

Article  PubMed  Google Scholar 

Oh K, Kang HM, Leem D, Lee H, Seo KY, Yoon S. Early detection of diabetic retinopathy based on deep learning and ultra-wide-field fundus images. Sci Rep 2021;11:1897.

Park JH, Kim JE, Gu JY, Yoo HJ, Park SH, Kim YI, Nam-Goong IS, Kim ES, Kim HK. Evaluation of circulating markers of Neutrophil Extracellular trap (NET) formation as risk factors for Diabetic Retinopathy in a case-control Association Study. Experimental and clinical endocrinology & diabetes: official journal. German Soc Endocrinol [and] German Diabetes Association. 2016;124(9):557–61. eng.

Article  Google Scholar 

Petrovski G, Kaarniranta K, Petrovič D. 2017. Oxidative Stress, Epigenetics, Environment, and Epidemiology of Diabetic Retinopathy. Journal of diabetes research. 2017:6419357. eng.

Qin X, Zou H. The role of lipopolysaccharides in diabetic retinopathy. BMC Ophthalmol. 2022;22(1):86. eng.

Article  PubMed  PubMed Central  Google Scholar 

Rao H, Jalali JA, Johnston TP, Koulen P. 2021. Emerging Roles of Dyslipidemia and Hyperglycemia in Diabetic Retinopathy: Molecular Mechanisms and Clinical Perspectives. Frontiers in endocrinology. 12:620045. eng.

Rossol M, Heine H, Meusch U, Quandt D, Klein C, Sweet MJ, Hauschildt S. LPS-induced cytokine production in human monocytes and macrophages. Crit Rev Immunol. 2011;31(5):379–446. eng.

Article  PubMed  Google Scholar 

Semeraro F, Cancarini A, dell’Omo R, Rezzola S, Romano MR, Costagliola C. 2015. Diabetic Retinopathy: Vascular and Inflammatory Disease. Journal of diabetes research. 2015:582060. eng.

Serban D, Dascalu AM, Arsene AL, Tribus LC, Vancea G, Pantea Stoian A, Costea DO, Tudosie MS, Stana D, Cristea BM et al. 2023. Gut Microbiota Dysbiosis in Diabetic Retinopathy-Current Knowledge and Future Therapeutic Targets. Life (Basel, Switzerland). 13(4). eng.

Shimizu H, Sakimoto T, Yamagami S. Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation. Sci Rep. 2019;9(1):9596. eng.

Article  PubMed  PubMed Central  Google Scholar 

Solomon SD, Chew E, Duh EJ, Sobrin L, Sun JK, VanderBeek BL, Wykoff CC, Gardner TW. Diabetic Retinopathy: A position Statement by the American Diabetes Association. Diabetes Care. 2017;40(3):412–8. eng.

Article  PubMed  PubMed Central  Google Scholar 

Suez J, Zmora N, Segal E, Elinav E. The pros, cons, and many unknowns of probiotics. Nat Med. 2019;25(5):716–29. eng.

Article  PubMed  Google Scholar 

Vagaja NN, Binz N, McLenachan S, Rakoczy EP, McMenamin PG. Influence of endotoxin-mediated retinal inflammation on phenotype of diabetic retinopathy in Ins2 akita mice. Br J Ophthalmol. 2013;97(10):1343–50. eng.

Article  PubMed  Google Scholar 

Wang ZH, Davis BB, Jiang DQ, Zhao TT, Xu DY. Soluble epoxide hydrolase inhibitors and cardiovascular diseases. Curr Vasc Pharmacol. 2013;11(1):105–11. eng.

Article  PubMed  Google Scholar 

Wu Z. Transcriptomic analysis reveals oxidative stress-related signature and molecular subtypes in cholangio carcinoma. Mol Genet Genomics: MGG. 2024;299(1):86. eng.

Article  PubMed  Google Scholar 

Wu Y, Sun Y, Dong X, Chen J, Wang Z, Chen J, Dong G. 2020. The Synergism of PGN, LTA and LPS in Inducing Transcriptome Changes, Inflammatory Responses and a Decrease in Lactation as Well as the Associated Epigenetic Mechanisms in Bovine Mammary Epithelial Cells. Toxins. 12(6). eng.

Wu H, Wang M, Li X, Shao Y. The Metaflammatory and Immunometabolic Role of Macrophages and Microglia in Diabetic Retinopathy. Hum Cell. 2021;34(6):1617–28. eng.

Article  PubMed  Google Scholar 

Xu H, Chen M. Diabetic retinopathy and dysregulated innate immunity. Vision Res. 2017;139:39–46. eng.

Article  PubMed  Google Scholar 

Yang T, Song B, Zhang J, Yang GS, Zhang H, Yu WF, Wu MC, Lu JH, Shen F. STK33 promotes hepatocellular carcinoma through binding to c-Myc. Gut. 2016;65(1):124–33. eng.

Article  PubMed  Google Scholar 

Yang G, Wei J, Liu P, Zhang Q, Tian Y, Hou G, Meng L, Xin Y, Jiang X. 2021. Role of the gut microbiota in type 2 diabetes and related diseases. Metabolism: clinical and experimental. 117:154712. eng.

Zhang S, Wu H, Wang K, Liu M. 2019. STK33/ERK2 signal pathway contribute the tumorigenesis of colorectal cancer HCT15 cells. Bioscience reports. 39(3). eng.

Zong H, Ward M, Stitt AW. AGEs, RAGE, and diabetic retinopathy. Curr Diab Rep. 2011;11(4):244–52. eng.

Article  PubMed  Google Scholar 

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