Innate immune memory in chronic HIV and HIV-associated neurocognitive disorders (HAND): potential mechanisms and clinical implications

Abbas F, Cenac C, Youness A, Azar P, Delobel P, Guery JC (2022) HIV-1 infection enhances innate function and TLR7 expression in female plasmacytoid dendritic cells. Life Sci Alliance 5. https://doi.org/10.26508/lsa.202201452

Abraham J, Jang S, Godbout JP, Chen J, Kelley KW, Dantzer R, Johnson RW (2008) Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120. Neurobiol Aging 29:614–621. https://doi.org/10.1016/j.neurobiolaging.2006.11.002

Article  CAS  PubMed  Google Scholar 

Adlam C, Broughton ES, Scott MT (1972) Enhanced resistance of mice to infection with bacteria following pre-treatment with Corynebacterium parvum. Nat New Biol 235:219–220. https://doi.org/10.1038/newbio235219a0

Article  CAS  PubMed  Google Scholar 

Allen NJ, Barres BA (2009) Neuroscience: Glia - more than just brain glue. Nature 457:675–677. https://doi.org/10.1038/457675a

Article  CAS  PubMed  Google Scholar 

Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D (2008) Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS ONE 3:e2516. https://doi.org/10.1371/journal.pone.0002516

Article  CAS  PubMed  PubMed Central  Google Scholar 

Anesten B, Zetterberg H, Nilsson S, Brew BJ, Fuchs D, Price RW, Gisslen M, Yilmaz A (2021) Effect of antiretroviral treatment on blood-brain barrier integrity in HIV-1 infection. BMC Neurol 21:494. https://doi.org/10.1186/s12883-021-02527-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aregay A, Engel B, Port K, Vondran FWR, Bremer B, Niehaus C, Khera T, Richter N, Jaeckel E, Cornberg M, Taubert R, Wedemeyer H (2021) Distinct Immune Imprints of Post-Liver Transplantation Hepatitis C Persist Despite Viral Clearance. Liver Transpl 27:887–899. https://doi.org/10.1002/lt.26031

Article  PubMed  Google Scholar 

Arts RJ, Novakovic B, Ter Horst R, Carvalho A, Bekkering S, Lachmandas E, Rodrigues F, Silvestre R, Cheng SC, Wang SY, Habibi E, Goncalves LG, Mesquita I, Cunha C, van Laarhoven A, van de Veerdonk FL, Williams DL, van der Meer JW, Logie C, O’Neill LA, Dinarello CA, Riksen NP, van Crevel R, Clish C, Notebaart RA, Joosten LA, Stunnenberg HG, Xavier RJ, Netea MG (2016) Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metab 24:807–819. https://doi.org/10.1016/j.cmet.2016.10.008

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arts RJW, Moorlag S, Novakovic B, Li Y, Wang SY, Oosting M, Kumar V, Xavier RJ, Wijmenga C, Joosten LAB, Reusken C, Benn CS, Aaby P, Koopmans MP, Stunnenberg HG, van Crevel R, Netea MG (2018) BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. Cell Host Microbe 23:89–100e5. https://doi.org/10.1016/j.chom.2017.12.010

Article  CAS  PubMed  Google Scholar 

Autenrieth CS, Beck EJ, Stelzle D, Mallouris C, Mahy M, Ghys P (2018) Global and regional trends of people living with HIV aged 50 and over: Estimates and projections for 2000–2020. PLoS ONE 13:e0207005. https://doi.org/10.1371/journal.pone.0207005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baik SH, Kang S, Lee W, Choi H, Chung S, Kim JI, Mook-Jung I (2019) A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer’s Disease. Cell Metab 30:493–507e6. https://doi.org/10.1016/j.cmet.2019.06.005

Article  CAS  PubMed  Google Scholar 

Bekkering S, Quintin J, Joosten LA, van der Meer JW, Netea MG, Riksen NP (2014) Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes. Arterioscler Thromb Vasc Biol 34:1731–1738. https://doi.org/10.1161/ATVBAHA.114.303887

Article  CAS  PubMed  Google Scholar 

Bekkering S, van den Munckhof I, Nielen T, Lamfers E, Dinarello C, Rutten J, de Graaf J, Joosten LA, Netea MG, Gomes ME, Riksen NP (2016) Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo. Atherosclerosis 254:228–236. https://doi.org/10.1016/j.atherosclerosis.2016.10.019

Article  CAS  PubMed  Google Scholar 

Bekkering S, Arts RJW, Novakovic B, Kourtzelis I, van der Heijden C, Li Y, Popa CD, Ter Horst R, van Tuijl J, Netea-Maier RT, van de Veerdonk FL, Chavakis T, Joosten LAB, van der Meer JWM, Stunnenberg H, Riksen NP, Netea MG (2018) Metabolic Induction of Trained Immunity through the Mevalonate Pathway. Cell 172:135–146e9. https://doi.org/10.1016/j.cell.2017.11.025

Article  CAS  PubMed  Google Scholar 

Bekkering S, Stiekema LCA, Bernelot Moens S, Verweij SL, Novakovic B, Prange K, Versloot M, Roeters van Lennep JE, Stunnenberg H, de Winther M, Stroes ESG, Joosten LAB, Netea MG, Riksen NP (2019) Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia. Cell Metab 30:1–2. https://doi.org/10.1016/j.cmet.2019.05.014

Article  CAS  PubMed  Google Scholar 

Bekkering S, Dominguez-Andres J, Joosten LAB, Riksen NP, Netea MG (2021) Trained Immunity: Reprogramming Innate Immunity in Health and Disease. Annu Rev Immunol 39:667–693. https://doi.org/10.1146/annurev-immunol-102119-073855

Article  CAS  PubMed  Google Scholar 

Ben Haij N, Planes R, Leghmari K, Serrero M, Delobel P, Izopet J, BenMohamed L, Bahraoui E (2015) HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-kappaB Pathway. PLoS ONE 10:e0129425. https://doi.org/10.1371/journal.pone.0129425

Article  CAS  PubMed  PubMed Central  Google Scholar 

Benn CS, Netea MG, Selin LK, Aaby P (2013) A small jab - a big effect: nonspecific immunomodulation by vaccines. Trends Immunol 34:431–439. https://doi.org/10.1016/j.it.2013.04.004

Article  CAS  PubMed  Google Scholar 

Biering-Sorensen S, Aaby P, Lund N, Monteiro I, Jensen KJ, Eriksen HB, Schaltz-Buchholzer F, Jorgensen ASP, Rodrigues A, Fisker AB, Benn CS (2017) Early BCG-Denmark and Neonatal Mortality Among Infants Weighing < 2500 g: A Randomized Controlled Trial. Clin Infect Dis 65:1183–1190. https://doi.org/10.1093/cid/cix525

Article  PubMed  PubMed Central  Google Scholar 

Bilbo SD (2010) Early-life infection is a vulnerability factor for aging-related glial alterations and cognitive decline. Neurobiol Learn Mem 94:57–64. https://doi.org/10.1016/j.nlm.2010.04.001

Article  PubMed  PubMed Central  Google Scholar 

Bistoni F, Vecchiarelli A, Cenci E, Puccetti P, Marconi P, Cassone A (1986) Evidence for macrophage-mediated protection against lethal Candida albicans infection. Infect Immun 51:668–674. https://doi.org/10.1128/iai.51.2.668-674.1986

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bistoni F, Verducci G, Perito S, Vecchiarelli A, Puccetti P, Marconi P, Cassone A (1988) Immunomodulation by a low-virulence, agerminative variant of Candida albicans. Further evidence for macrophage activation as one of the effector mechanisms of nonspecific anti-infectious protection. J Med Vet Mycol 26:285–299. https://doi.org/10.1080/02681218880000401

Article  CAS  PubMed  Google Scholar 

Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, Beilman GJ, Nguyen PL, Khoruts A, Larson M, Haase AT, Douek DC (2004) CD4 + T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 200:749–759. https://doi.org/10.1084/jem.20040874

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC (2006) Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 12:1365–1371. https://doi.org/10.1038/nm1511

Article  CAS  PubMed  Google Scholar 

Brown GC (2019) The endotoxin hypothesis of neurodegeneration. J Neuroinflammation 16:180. https://doi.org/10.1186/s12974-019-1564-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Calcagno A, Romito A, Atzori C, Ghisetti V, Cardellino C, Audagnotto S, Scarvaglieri E, Lipani F, Imperiale D, Di Perri G, Bonora S (2017) Blood Brain Barrier Impairment in HIV-Positive Naive and Effectively Treated Patients: Immune Activation Versus Astrocytosis. J Neuroimmune Pharmacol 12:187–193. https://doi.org/10.1007/s11481-016-9717-2

留言 (0)

沒有登入
gif