Hormonal interventions in skin wounds – a mini review

Abtahi S, Driessen JHM, Burden AM, Souverein PC, van den Bergh JP, van Staa TP, et al. Low-dose oral glucocorticoid therapy and risk of osteoporotic fractures in patients with rheumatoid arthritis: a cohort study using the clinical Practice Research Datalink. Rheumatology (Oxford). 2022;61:1448–58. https://doi.org/10.1093/rheumatology/keab548.

Article  CAS  PubMed  Google Scholar 

Ahn S, Chantre CO, Ardoña HAM, Gonzalez GM, Campbell PH, Parker KK. Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor β. Biomaterials. 2020;255:120149. https://doi.org/10.1016/j.biomaterials.2020.120149.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akishita M. Hormone replacement therapy and geriatric medicine: future perspectives. Nippon Ronen Igakkai Zasshi. Japanese J Geriatr. 2009;46:327–9. https://doi.org/10.3143/geriatrics.46.327.

Article  Google Scholar 

Barret JP, Dziewulski P, Jeschke MG, Wolf SE, Herndon DN. Effects of recombinant human growth hormone on the development of burn scarring. Plast Reconstr Surg. 1999;104:726–9. https://doi.org/10.1097/00006534-199909030-00017.

Article  CAS  PubMed  Google Scholar 

Bentley C, Hazeldine J, Bravo L, Taylor AE, Gilligan LC, Shaheen F, et al. The ultra-acute steroid response to traumatic injury: a cohort study. Eur J Endocrinol. 2023;188. https://doi.org/10.1093/ejendo/lvad024.

Bernelot Moens SJ, Schnitzler GR, Nickerson M, Guo H, Ueda K, Lu Q, et al. Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury. Circulation. 2012;126:1993–2004. https://doi.org/10.1161/circulationaha.112.124529.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boraldi F, Lofaro FD, Bonacorsi S, Mazzilli A, Garcia-Fernandez M, Quaglino D. The role of fibroblasts in skin homeostasis and repair. Biomedicines. 2024;12. https://doi.org/10.3390/biomedicines12071586.

Brazel CB, Simon JC, Tuckermann JP, Saalbach A. Inhibition of 11β-HSD1 expression by insulin in skin: Impact for Diabetic Wound Healing. J Clin Med. 2020;9. https://doi.org/10.3390/jcm9123878.

Breederveld RS, Tuinebreijer WE. Recombinant human growth hormone for treating burns and donor sites. Cochrane Database Syst Rev. 2012;12:Cd008990. https://doi.org/10.1002/14651858.CD008990.pub2.

Article  PubMed  Google Scholar 

Breederveld RS, Tuinebreijer WE. Recombinant human growth hormone for treating burns and donor sites. Cochrane Database Syst Rev. 2014. https://doi.org/10.1002/14651858.CD008990.pub3. 2014:Cd008990.

Article  PubMed  PubMed Central  Google Scholar 

Chi L, Liu C, Gribonika I, Gschwend J, Corral D, Han SJ, et al. Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis. Science. 2024;384:eadk6200. https://doi.org/10.1126/science.adk6200.

Article  CAS  PubMed  Google Scholar 

Cousins FL, Kirkwood PM, Murray AA, Collins F, Gibson DA, Saunders PT. Androgens regulate scarless repair of the endometrial wound in a mouse model of menstruation. Faseb j. 2016;30:2802–11. https://doi.org/10.1096/fj.201600078R.

Article  CAS  PubMed  Google Scholar 

Cristóbal L, de Los Reyes N, Ortega MA, Álvarez-Mon M, García-Honduvilla N, Buján J, et al. Local growth hormone therapy for pressure Ulcer Healing on a human skin mouse model. Int J Mol Sci. 2019;20. https://doi.org/10.3390/ijms20174157.

Dosh MGEB, Haidar L, Gerges H, Baassiri A, Leone S. Nerve growth factor and burn wound healing: update of molecular interactions with skin cells. Burns. 2023;49:989–1002. https://doi.org/10.1016/j.burns.2022.11.001.

Article  PubMed  Google Scholar 

El Mohtadi M, Whitehead K, Dempsey-Hibbert N, Belboul A, Ashworth J. Estrogen deficiency - a central paradigm in age-related impaired healing? Excli j. 2021;20:99–116. https://doi.org/10.17179/excli2020-3210.

Article  PubMed  PubMed Central  Google Scholar 

Farzan SF, Karagas MR, Christensen BC, Li Z, Kuriger JK, Nelson HH. RNASEL and MIR146A SNP-SNP interaction as a susceptibility factor for non-melanoma skin cancer. PLoS ONE. 2014;9:e93602. https://doi.org/10.1371/journal.pone.0093602.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Frech S, Forsthuber A, Korosec A, Lipp K, Kozumov V, Lichtenberger BM. Hedgehog signaling in papillary fibroblasts is essential for hair follicle regeneration during Wound Healing. J Invest Dermatol. 2022;142:1737–e17481735. https://doi.org/10.1016/j.jid.2021.11.026.

Article  CAS  PubMed  Google Scholar 

Gärtner F, Gihring A, Roth A, Bischof J, Xu P, Elad L, et al. Obesity prolongs the inflammatory response in mice after severe trauma and attenuates the Splenic response to the Inflammatory Reflex. Front Immunol. 2021;12:745132. https://doi.org/10.3389/fimmu.2021.745132.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grodzielski M, Cidlowski JA. Glucocorticoids regulate thrombopoiesis by remodeling the megakaryocyte transcriptome. J Thromb Haemost. 2023;21:3207–23. https://doi.org/10.1016/j.jtha.2023.06.012.

Article  PubMed  PubMed Central  Google Scholar 

Herndon DN, Hawkins HK, Nguyen TT, Pierre E, Cox R, Barrow RE. Characterization of growth hormone enhanced donor site healing in patients with large cutaneous burns. Ann Surg. 1995;221:649–56. https://doi.org/10.1097/00000658-199506000-00004. discussion 656 – 649.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Horng HC, Chang WH, Yeh CC, Huang BS, Chang CP, Chen YJ, et al. Estrogen effects on Wound Healing. Int J Mol Sci. 2017;18. https://doi.org/10.3390/ijms18112325.

Huang RZ, Wang YW, Huang HY, Jiang RH, Xue NN, Yin SP, et al. [Application effect of a dual release system of androgen and its antagonist in the repair of full-thickness burn wounds in mice]. Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2024;40:180–9. https://doi.org/10.3760/cma.j.cn501225-20230802-00033.

Article  CAS  PubMed  Google Scholar 

Hundeshagen G, Blears E, Mertin V, Day AG, Palackic A, Tapking C, et al. Administration and effects of beta blockers and oxandrolone in severely burned adults: a post hoc analysis of the RE-ENERGIZE trial. Burns Trauma. 2024;12:tkad063. https://doi.org/10.1093/burnst/tkad063.

Article  PubMed  PubMed Central  Google Scholar 

Jin J, Pan BH, Wang KA, Yu SS, Wu GS, Fang H, et al. Subvacuum environment-enhanced cell migration promotes wound healing without increasing hypertrophic scars caused by excessive cell proliferation. Cell Prolif. 2023;56:e13493. https://doi.org/10.1111/cpr.13493.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kadmiel M, Janoshazi A, Xu X, Cidlowski JA. Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye. Exp Eye Res. 2016;152:10–33. https://doi.org/10.1016/j.exer.2016.08.020.

Article  CAS  PubMed  PubMed Central  Google Scholar 

LeBert DC, Huttenlocher A. Inflammation and wound repair. Semin Immunol. 2014;26:315–20. https://doi.org/10.1016/j.smim.2014.04.007.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee E, Lee MJ, Park B, Park I. Risk of fracture according to glucocorticoid use after renal biopsy: a nationwide population-based study. Sci Rep. 2020;10:13846. https://doi.org/10.1038/s41598-020-70935-w.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lopes FB, Sarandy MM, Novaes RD, Valacchi G, Gonçalves RV. OxInflammatory responses in the Wound Healing process: a systematic review. Antioxid (Basel). 2024;13. https://doi.org/10.3390/antiox13070823.

Moeinpour F, Choudhry MA, de Figueiredo LF, Bland KI, Chaudry IH. Estradiol’s salutary effects on keratinocytes following trauma-hemorrhage are mediated by estrogen receptor (ER)-alpha and ER-beta. Mol Med. 2008;14:689–96. https://doi.org/10.2119/2008-00068.Moeinpour.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mukai K, Horike SI, Meguro-Horike M, Nakajima Y, Iswara A, Nakatani T. Topical estrogen application promotes cutaneous wound healing in db/db female mice with type 2 diabetes. PLoS ONE. 2022;17:e0264572. https://doi.org/10.1371/journal.pone.0264572.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Niculet E, Bobeica C, Tatu AL. Glucocorticoid-Induced skin atrophy: the Old and the New. Clin Cosmet Investig Dermatol. 2020;13:1041–50. https://doi.org/10.2147/ccid.S224211.

Article  CAS  PubMed 

留言 (0)

沒有登入
gif