Fernandes, P. A. R. & Coimbra, M. A. The antioxidant activity of polysaccharides: a structure-function relationship overview. Carbohydr. Polym. 314, 120965 (2023).

Article  CAS  PubMed  Google Scholar 

Jin, W. et al. Glycosaminoglycans in neurodegenerative diseases. Adv. Exp. Med. Biol. 1325, 189–204 (2021).

Article  CAS  PubMed  Google Scholar 

Leal, A. F. et al. Mucopolysaccharidoses: cellular consequences of glycosaminoglycans accumulation and potential targets. Int. J. Mol. Sci. 24, 477 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Wang, Q. & Chi, L. The alterations and roles of glycosaminoglycans in human diseases. Polymers 14, 5014 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zappe, A. et al. State-of-the-art glycosaminoglycan characterization. Mass Spectrom. Rev. 41, 1040–1071 (2022).

Article  CAS  PubMed  Google Scholar 

Zaia, J. Glycosaminoglycan glycomics using mass spectrometry. Mol. Cell. Proteom. 12, 885–892 (2013).

Article  CAS  Google Scholar 

Volpi, N. Therapeutic applications of glycosaminoglycans. Curr. Med. Chem. 13, 1799–1810 (2006).

Article  CAS  PubMed  Google Scholar 

Lin, L. et al. Site-selective reactions for the synthesis of glycoconjugates in polysaccharide vaccine development. Carbohydr. Polym. 230, 115643 (2020).

Article  CAS  PubMed  Google Scholar 

Chang, X. et al. Glycosylated proteins with abnormal glycosylation changes are potential biomarkers for early diagnosis of breast cancer. Int. J. Biol. Macromol. 236, 123855 (2023).

Article  CAS  PubMed  Google Scholar 

Purushothaman, A. et al. The role of glycans in the mechanobiology of cancer. J. Biol. Chem. 299, 102935 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haslund-Gourley, B. S. et al. IgG N-glycan signatures as potential diagnostic and prognostic biomarkers. Diagnostics 13, 1016 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mechref, Y. et al. Mass spectrometry based biomarkers for early detection of HCC using a glycoproteomic approach. Adv. Cancer Res. 157, 23–56 (2023).

Article  CAS  PubMed  Google Scholar 

Li, J. et al. Recent advances in demystifying O-glycosylation in health and disease. Proteomics 22, e2200156 (2022).

Article  PubMed  Google Scholar 

Peric, L. et al. Glycosylation alterations in cancer cells, prognostic value of glycan biomarkers and their potential as novel therapeutic targets in breast cancer. Biomedicines 10, 3265 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Flevaris, K. & Kontoravdi, C. Immunoglobulin G N-glycan biomarkers for autoimmune diseases: current state and a glycoinformatics perspective. Int. J. Mol. Sci. 23, 5180 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wilczak, M. et al. Altered glycosylation in progression and management of bladder cancer. Molecules 28, 3436 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wieboldt, R. & Läubli, H. Glycosaminoglycans in cancer therapy. Am. J. Physiol. Cell Physiol. 322, C1187–C1200 (2022).

Article  CAS  PubMed  Google Scholar 

Deb, G. et al. Matrix proteoglycans in tumor inflammation and immunity. Am. J. Physiol. Cell Physiol. 323, C678–C693 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hoosen, Y. et al. Nanotechnology and glycosaminoglycans: paving the way forward for ovarian cancer intervention. Int. J. Mol. Sci. 19, 731 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Vallen, M. J. et al. Sulfated sugars in the extracellular matrix orchestrate ovarian cancer development: “when sweet turns sour”. Gynecol. Oncol. 135, 371–381 (2014).

Article  CAS  PubMed  Google Scholar 

Kizhakkeppurath Kumaran, A. et al. Proteoglycans in breast cancer, identification and characterization by LC-MS/MS assisted proteomics approach: a review. Proteom. Clin. Appl. 2023, e2200046 (2023).

Article  Google Scholar 

Nikitovic, D. et al. The motile breast cancer phenotype roles of proteoglycans/glycosaminoglycans. Biomed. Res. Int. 2014, 124321 (2014).

Article  PubMed  PubMed Central  Google Scholar 

Vicente, C. M. et al. Heparan sulfate proteoglycans in human colorectal cancer. Anal. Cell. Pathol. 2018, 8389595 (2018).

Article  Google Scholar 

Tanaka, Y. et al. Proteoglycans are attractive biomarkers and therapeutic targets in hepatocellular carcinoma. Int. J. Mol. Sci. 19, 3070 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Baghy, K. et al. Proteoglycans in liver cancer. World J. Gastroenterol. 22, 379–393 (2016).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hua, S. H. et al. Theranostic applications of glycosaminoglycans in metastatic renal cell carcinoma. Cancers 15, 266 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Hosein, A. N. et al. Pancreatic cancer stroma: an update on therapeutic targeting strategies. Nat. Rev. Gastroenterol. Hepatol. 17, 487–505 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Melstrom, L. G. et al. The pancreatic cancer microenvironment: a true double agent. J. Surg. Oncol. 116, 7–15 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lo, S. L. et al. Expression of heparan sulfate in gastric carcinoma and its correlation with clinicopathological features and patient survival. J. Clin. Pathol. 64, 153–158 (2011).

Article  PubMed  Google Scholar 

Scarini, J. F. et al. Heterogeneity and versatility of the extracellular matrix during the transition from pleomorphic adenoma to carcinoma ex pleomorphic adenoma: cumulative findings from basic research and new insights. Front. Oral. Health 4, 942604 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Marques, C. et al. Heparan sulfate biosynthesis and sulfation profiles as modulators of cancer signalling and progression. Front. Oncol. 11, 778752 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu, Y. & Cheung, A. L. M. Proteoglycans and their functions in esophageal squamous cell carcinoma. World J. Clin. Oncol. 12, 507–521 (2021).

Article  PubMed  PubMed Central  Google Scholar