Abadi AJ, Mirzaei S, Mahabady MK, Hashemi F, Zabolian A, Hashemi F, Raee P, Aghamiri S, Ashrafizadeh M, Aref AR (2022) Curcumin and its derivatives in cancer therapy: potentiating antitumor activity of cisplatin and reducing side effects. Phytother Res 36:189–213

Article  PubMed  CAS  Google Scholar 

Abd-Elmawla MA, Abdel Mageed SS, Al-Noshokaty TM, Elballal MS, Abulsoud AI, Elshaer SS, El-Husseiny AA, Fathi D, Midan HM, Rizk NI, Elrebehy MA, Sayed GA, Tabaa MME, Salman A, Mohammed OA, Ashraf A, Khidr EG, Khaled R, El-Dakroury WA, Helal GK, Moustafa YM, Doghish AS (2023) Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma. Pathol Res Pract 250:154817

Article  PubMed  CAS  Google Scholar 

Abdelazim EB, Abed T, Goher SS, Alya SH, El-Nashar HA, El-Moslamy SH, El-Fakharany EM, Abdul-Baki EA, Shakweer MM, Eissa NG (2024) In vitro and in vivo studies of Syzygium cumini-loaded electrospun PLGA/PMMA/collagen nanofibers for accelerating topical wound healing. RSC Adv 14:101–117

Article  PubMed  PubMed Central  CAS  Google Scholar 

Abdelmaksoud NM, Sallam AM, Abulsoud AI, El-Dakroury WA, Abdel Mageed SS, Al-Noshokaty TM, Elrebehy MA, Elshaer SS, Mahmoud NA, Fathi D, Rizk NI, Elballal MS, Mohammed OA, Abdel-Reheim MA, Zaki MB, Saber S, Doghish AS (2024) Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer’s disease. Pathol Res Pract 253:155007

Article  PubMed  CAS  Google Scholar 

Abtin M, Nafisi N, Hosseinzadeh A, Kadkhoda S, Omranipour R, Sahebi L, Razipour M, Ghafouri-Fard S, Shakoori A (2024) Inhibition of breast cancer cell growth and migration through siRNA-mediated modulation of circ_0009910/miR-145-5p/MUC1 axis. Non-coding RNA Res 9:367–375

Article  CAS  Google Scholar 

Ahir M, Upadhyay P, Ghosh A, Sarker S, Bhattacharya S, Gupta P, Ghosh S, Chattopadhyay S, Adhikary A (2020) Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy. Biomaterials Sci 8:2939–2954

Article  CAS  Google Scholar 

Ahmed F, Ijaz B, Ahmad Z, Farooq N, Sarwar MB, Husnain T (2020) Modification of miRNA Expression through plant extracts and compounds against breast cancer: Mechanism and translational significance. Phytomedicine 68:153168

Article  PubMed  CAS  Google Scholar 

Akbaribazm M, Khazaei F, Naseri L, Pazhouhi M, Zamanian M, Khazaei M (2021) Pharmacological and therapeutic properties of the Red Clover (Trifolium pratense L.): an overview of the new findings. J Tradit Chin Med 41

Alessio E, Bonadio RS, Buson L, Chemello F, Cagnin S (2020) A Single Cell but Many Different Transcripts: A Journey into the World of Long Non-Coding RNAs. 21: 302

Alnuqaydan AM (2020) Targeting micro-RNAs by natural products: A novel future therapeutic strategy to combat cancer. Am J Translational Res 12:3531

CAS  Google Scholar 

Aly SH, Elissawy AM, Eldahshan OA, Elshanawany MA, Efferth T, Singab ANB (2019) The pharmacology of the genus Sophora (Fabaceae): An updated review. Phytomedicine 64:153070

Article  PubMed  CAS  Google Scholar 

Aly SH, Elissawy AM, Fayez AM, Eldahshan OA, Elshanawany MA, Singab ANB (2021) Neuroprotective effects of Sophora secundiflora, Sophora tomentosa leaves and formononetin on scopolamine-induced dementia. Nat Prod Res 35:5848–5852

Article  PubMed  CAS  Google Scholar 

Aly SH, Elbadry AM, El-Shazly M, Hwang T-L (2023a) Exploring the potential role of genus Sophora in the management of osteoporosis: a phytochemical and biological review. Front Nat Prod 2:1302371

Article  Google Scholar 

Aly SH, Elissawy AM, Mahmoud AM, El-Tokhy FSe, Mageed SSA, Almahli H, Al-Rashood ST, Binjubair FA, Hassab MAE, Eldehna WM (2023b) Synergistic effect of Sophora japonica and Glycyrrhiza glabra flavonoid-rich fractions on wound healing: in vivo and molecular docking studies. Molecules 28:2994

Article  PubMed  PubMed Central  CAS  Google Scholar 

Aly SH, Elbadry AM, Doghish AS, El-Nashar HA (2024a) Unveiling the pharmacological potential of plant triterpenoids in breast cancer management: An updated review. Naunyn-Schmiedeberg’s Archives of Pharmacology: 1–26

Aly SH, Elissawy AM, El Hassab MA, Majrashi TA, Hassan FE, Elkaeed EB, Eldehna WM, Singab ANB (2024b) Comparative metabolic study of the chloroform fraction of three Cystoseira species based on UPLC/ESI/MS analysis and biological activities. J Enzyme Inhib Med Chem 39:2292482

Article  PubMed  Google Scholar 

Amirikia KC, Mills P, Bush J, Newman LA (2011) Higher population-based incidence rates of triple‐negative breast cancer among young African‐American women: implications for breast cancer screening recommendations. Cancer 117:2747–2753

Article  PubMed  Google Scholar 

Ashrafizadeh M, Najafi M, Makvandi P, Zarrabi A, Farkhondeh T, Samarghandian S (2020a) Versatile role of curcumin and its derivatives in lung cancer therapy. J Cell Physiol 235:9241–9268

Article  PubMed  CAS  Google Scholar 

Ashrafizadeh M, Zarrabi A, Hashemi F, Moghadam ER, Hashemi F, Entezari M, Hushmandi K, Mohammadinejad R, Najafi M (2020b) Curcumin in cancer therapy: A novel adjunct for combination chemotherapy with paclitaxel and alleviation of its adverse effects. Life Sci 256:117984

Article  PubMed  CAS  Google Scholar 

Ashrafizadeh M, Zarrabi A, Hashemi F, Zabolian A, Saleki H, Bagherian M, Azami N, Bejandi AK, Hushmandi K, Ang HL (2020c) Polychemotherapy with curcumin and doxorubicin via biological nanoplatforms: enhancing antitumor activity. Pharmaceutics 12:1084

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ashrafizadeh M, Zarrabi A, Hashemipour M, Vosough M, Najafi M, Shahinozzaman M, Hushmandi K, Khan H, Mirzaei H (2020d) Sensing the scent of death: modulation of microRNAs by curcumin in gastrointestinal cancers. Pharmacol Res 160:105199

Article  PubMed  CAS  Google Scholar 

Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R (2008) Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev 22:2773–2785

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bamji SF, Corbitt C (2017) Glyceollins: Soybean phytoalexins that exhibit a wide range of health-promoting effects. J Funct Foods 34:98–105

Article  CAS  Google Scholar 

Bravo-Vázquez LA, Méndez-García A, Rodríguez AL, Sahare P, Pathak S, Banerjee A, Duttaroy AK, Paul S (2023) Applications of nanotechnologies for miRNA-based cancer therapeutics: current advances and future perspectives. Front Bioeng Biotechnol 11:1208547

Article  PubMed  PubMed Central  Google Scholar 

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J Clin 74:229–263

Article  Google Scholar 

Burns J, Yokota T, Ashihara H, Lean ME, Crozier A (2002) Plant foods and herbal sources of resveratrol. J Agric Food Chem 50:3337–3340

Article  PubMed  CAS  Google Scholar 

Cansaran-Duman D, Tanman Ü, Yangın S, Atakol O (2020) The comparison of miRNAs that respond to anti-breast cancer drugs and usnic acid for the treatment of breast cancer. Cytotechnology 72:855–872

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cansaran-Duman D, Yangin S, Çolak B (2021) The role of vulpinic acid as a natural compound in the regulation of breast cancer-associated miRNAs. Biol Res 54

Cao L, Wang M, Dong Y, Xu B, Chen J, Ding Y, Qiu S, Li L, Karamfilova Zaharieva E, Zhou X, Xu Y (2020) Circular RNA circRNF20 promotes breast cancer tumorigenesis and Warburg effect through miR-487a/HIF-1α/HK2. Cell Death Dis 11:145

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chakrabortty A, Patton DJ, Smith BF, Agarwal P (2023) miRNAs: Potential as Biomarkers and Therapeutic Targets for Cancer. Genes 14

Chaudhari R, Nasra S, Meghani N, Kumar A (2022) MiR-206 conjugated gold nanoparticle based targeted therapy in breast cancer cells. Sci Rep 12:4713

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chen B, Li H, Zeng X, Yang P, Liu X, Zhao X, Liang S (2012) Roles of microRNA on cancer cell metabolism. J translational Med 10:1–12

Article  CAS  Google Scholar 

Chen J, Duan Y, Zhang X, Ye Y, Ge B, Chen J (2015) Genistein induces apoptosis by the inactivation of the IGF-1R/p-Akt signaling pathway in MCF-7 human breast cancer cells. Food Funct 6:995–1000

Article  PubMed  CAS  Google Scholar 

Chen P, He YH, Huang X, Tao SQ, Wang XN, Yan H, Ding KS, Lobie PE, Wu WY, Wu ZS (2017) MiR-23a modulates X-linked inhibitor of apoptosis-mediated autophagy in human luminal breast cancer cell lines. Oncotarget 8:80709–80721

Article  PubMed  PubMed Central  Google Scholar 

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