Cao J, Zeng F, Liao S, Cao L, Zhou Y (2023) Effects of glycolysis on the polarization and function of tumor–associated macrophages (review). Int J Oncol 62. https://doi.org/10.3892/ijo.2023.5518

Chawla M, Roy P, Basak S (2021) Role of the NF-kappaB system in context-specific tuning of the inflammatory gene response. Curr Opin Immunol 68:21–27. https://doi.org/10.1016/j.coi.2020.08.005

Article  CAS  PubMed  Google Scholar 

Chen X, Liu Y, Gao Y, Shou S, Chai Y (2021) The roles of macrophage polarization in the host immune response to sepsis. Int Immunopharmacol 96:107791. https://doi.org/10.1016/j.intimp.2021.107791

Article  CAS  PubMed  Google Scholar 

Chen R et al (2022) Macrophage Sprouty4 deficiency diminishes sepsis-induced acute lung injury in mice. Redox Biol 58:102513. https://doi.org/10.1016/j.redox.2022.102513

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Y, Yang L, Li X (2023) Advances in mesenchymal stem cells regulating macrophage polarization and treatment of sepsis-induced liver. Injury Front Immunol 14:1238972. https://doi.org/10.3389/fimmu.2023.1238972

Article  CAS  PubMed  Google Scholar 

Enchev RI, Schulman BA, Peter M (2015) Protein neddylation: beyond cullin-RING ligases. Nat Rev Mol Cell Biol 16:30–44. https://doi.org/10.1038/nrm3919

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fu Z, Liao W, Ma H, Wang Z, Jiang M, Feng X, Zhang W (2019) Inhibition of neddylation plays protective role in lipopolysaccharide-induced kidney damage through CRL-mediated NF-kappaB pathways. Am J Transl Res 11:2830–2842

CAS  PubMed  PubMed Central  Google Scholar 

He ZX et al (2023) Targeting cullin neddylation for cancer and. Fibrotic Dis Theranostics 13:5017–5056. https://doi.org/10.7150/thno.78876

Article  CAS  Google Scholar 

Jiang Y, Li L, Li Y, Liu G, Hoffman RM, Jia L (2021) Neddylation regulates macrophages and implications for Cancer Therapy Front. Cell Dev Biol 9:681186. https://doi.org/10.3389/fcell.2021.681186

Article  Google Scholar 

Jiao Y et al (2021) Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury. Crit Care 25:356. https://doi.org/10.1186/s13054-021-03775-3

Article  PubMed  PubMed Central  Google Scholar 

Liu YC, Zou XB, Chai YF, Yao YM (2014) Macrophage polarization in inflammatory diseases. Int J Biol Sci 10:520–529. https://doi.org/10.7150/ijbs.8879

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu D et al (2022) Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options. Mil Med Res 9:56. https://doi.org/10.1186/s40779-022-00422-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lu Y, Yang X (2020) The pivotal roles of neddylation pathway in immunoregulation. Immun Inflamm Dis 8:782–792. https://doi.org/10.1002/iid3.335

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nakajima S, Kato H, Takahashi S, Johno H, Kitamura M (2011) Inhibition of NF-kappaB by MG132 through ER stress-mediated induction of LAP and LIP. FEBS Lett 585:2249–2254. https://doi.org/10.1016/j.febslet.2011.05.047

Article  CAS  PubMed  Google Scholar 

Nedeva C (2021) Inflammation and cell death of the Innate and Adaptive Immune System during Sepsis Biomolecules. 11. https://doi.org/10.3390/biom11071011

Torres LK, Pickkers P, van der Poll T (2022) Sepsis-Induced Immunosuppression Annu Rev Physiol 84:157–181. https://doi.org/10.1146/annurev-physiol-061121-040214

Article  CAS  PubMed  Google Scholar 

Viola A, Munari F, Sanchez-Rodriguez R, Scolaro T, Castegna A (2019) The metabolic signature of macrophage. Responses Front Immunol 10:1462. https://doi.org/10.3389/fimmu.2019.01462

Article  CAS  PubMed  Google Scholar 

Wang Z, Wang Z (2023) The role of macrophages polarization in sepsis-induced acute lung injury. Front Immunol 14:1209438. https://doi.org/10.3389/fimmu.2023.1209438

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang X et al (2023) Matrine suppresses NLRP3 inflammasome activation via regulating PTPN2/JNK/SREBP2 pathway. sepsis Phytomedicine 109:154574. https://doi.org/10.1016/j.phymed.2022.154574

Article  CAS  PubMed  Google Scholar 

Xu J et al (2023) NLRC3 expression in macrophage impairs glycolysis and host immune defense by modulating the NF-kappaB-NFAT5 complex during septic immunosuppression. Mol Ther 31:154–173. https://doi.org/10.1016/j.ymthe.2022.08.023

Article  CAS  PubMed  Google Scholar 

Yan S et al (2023) CTRP6 regulates M1 macrophage polarization via the PPAR-gamma/NF-kappaB pathway and reprogramming glycolysis in recurrent spontaneous abortion. Int Immunopharmacol 124:110840. https://doi.org/10.1016/j.intimp.2023.110840

Article  CAS  PubMed  Google Scholar 

Zeng R et al (2024) Neddylation suppression by a macrophage membrane-coated nanoparticle promotes dual immunomodulatory repair of diabetic wounds. Bioact Mater 34:366–380. https://doi.org/10.1016/j.bioactmat.2023.12.025

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou L, Jiang Y, Luo Q, Li L, Jia L (2019) Neddylation: a novel modulator of the tumor microenvironment. Mol Cancer 18:77. https://doi.org/10.1186/s12943-019-0979-1

Article  PubMed  PubMed Central  Google Scholar 

Zhu L, Zhao Q, Yang T, Ding W, Zhao Y (2015) Cellular metabolism and macrophage functional polarization. Int Rev Immunol 34:82–100. https://doi.org/10.3109/08830185.2014.969421

Article  CAS  PubMed  Google Scholar 

Zhu CL et al (2022a) Dysregulation of neutrophil death in sepsis. Front Immunol 13:963955. https://doi.org/10.3389/fimmu.2022.963955

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu J, Chu F, Zhang M, Sun W, Zhou F (2022b) Association between Neddylation and Immune Response Front. Cell Dev Biol 10:890121. https://doi.org/10.3389/fcell.2022.890121

Article  Google Scholar 

Zou T, Zhang J (2021) Diverse and pivotal roles of neddylation in metabolism and immunity. FEBS J 288:3884–3912. https://doi.org/10.1111/febs.15584

Article  CAS  PubMed  Google Scholar