Abadi AJ, Zarrabi A, Gholami MH, Mirzaei S, Hashemi F, Zabolian A, Entezari M, Hushmandi K, Ashrafizadeh M, Khan H (2021) Small in size, but large in action: microRNAs as potential modulators of PTEN in breast and lung cancers. Biomolecules 11:304

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abusaiba THH, Hussein AA (2024) microRNA Biogenesis, Mechanisms of Actions and Circulation. Qeios 4:(1–8)

Alnuqaydan AM (2020) Targeting micro-RNAs by natural products: A novel future therapeutic strategy to combat cancer. Am J Transl Res 12:3531

CAS  PubMed  PubMed Central  Google Scholar 

Asgharian P, Tazekand AP, Hosseini K, Forouhandeh H, Ghasemnejad T, Ranjbar M, Hasan M, Kumar M, Beirami SM, Tarhriz V (2022) Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets. Cancer Cell Int 22:257

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ashrafizadeh M, Zarrabi A, Orouei S, Hushmandi K, Hakimi A, Zabolian A, Daneshi S, Samarghandian S, Baradaran B, Najafi M (2021a) MicroRNA-mediated autophagy regulation in cancer therapy: the role in chemoresistance/chemosensitivity. Eur J Pharmacol 892:173660

Article  CAS  PubMed  Google Scholar 

Ashrafizadeh M, Zarrabi A, Orouei S, Zabolian A, Saleki H, Azami N, Bejandi AK, Mirzaei S, Janaghard MN, Hushmandi K (2021b) Interplay between SOX9 transcription factor and microRNAs in cancer. Int J Biol Macromol 183:681–694

Article  CAS  PubMed  Google Scholar 

Bautista-Sánchez D, Arriaga-Canon C, Pedroza-Torres A, De La Rosa-Velázquez IA, González-Barrios R, Contreras-Espinosa L, Montiel-Manríquez R, Castro-Hernández C, Fragoso-Ontiveros V, Álvarez-Gómez RM (2020) The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics. Mol Ther-Nucleic Acids 20:409–420

Article  PubMed  PubMed Central  Google Scholar 

Bhattacharyya A, Kumar H, Mishra P, Panda A, Dash K, Adhikary T (2023) CRISPR technology-a new horizon in clinical dentistry-a review. Bangladesh J Med Sci 22:42–46

Article  Google Scholar 

Bloebaum M, Poort L, Böckmann R, Kessler P (2014) Survival after curative surgical treatment for primary oral squamous cell carcinoma. J Cranio-Maxillofac Surg 42:1572–1576

Article  CAS  Google Scholar 

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: Cancer J Clin 74:229–263

PubMed  Google Scholar 

Chai AWY, Yee PS, Price S, Yee SM, Lee HM, Tiong VK, Gonçalves E, Behan FM, Bateson J, Gilbert J (2020) Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway. Elife 9:e57761

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chattopadhyay E, Singh R, Ray A, Roy R, De Sarkar N, Paul RR, Pal M, Aich R, Roy B (2016) Expression deregulation of mir31 and CXCL12 in two types of oral precancers and cancer: Importance in progression of precancer and cancer. Sci Rep 6:32735

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen J-H, Wu AT, Bamodu OA, Yadav VK, Chao T-Y, Tzeng Y-M, Mukhopadhyay D, Hsiao M, Lee J-C (2019) Ovatodiolide suppresses oral cancer malignancy by down-regulating exosomal Mir-21/STAT3/β-catenin cargo and preventing oncogenic transformation of normal gingival fibroblasts. Cancers 12:56

Article  PubMed  PubMed Central  Google Scholar 

Deng Z, Lu L, Li B, Shi X, Jin H, Hu W (2023) The roles of inflammasomes in cancer. Front Immunol 14:1195572

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dinesh Y, Ramani P, Yuwanati M, Ramalingam K, Gheena S (2023) MicroRNA profiling in circulating exosomes in oral squamous cell carcinoma: a systematic review. Cureus 15:1–13

Google Scholar 

Doghish AS, El-Husseiny AA, Khidr EG, Elrebehy MA, Elballal MS, Abdel-Reheim MA, Mageed SSA, Zaki MB, Mohammed OA, Khaled R (2023a) Decoding the role of miRNAs in oral cancer pathogenesis: A focus on signaling pathways. Pathol-Res Pract 252:1–14

Article  Google Scholar 

Doghish AS, Elshaer SS, Fathi D, Rizk NI, Elrebehy MA, Al-Noshokaty TM, Elballal MS, Abdelmaksoud NM, Abdel-Reheim MA, Mageed SSA (2023b) Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of oral cancer. Pathol-Res Pract 253:1–26

Google Scholar 

Elballal MS, Sallam A-AM, Elesawy AE, Shahin RK, Midan HM, Elrebehy MA, Elazazy O, El-Boghdady RM, Blasy SH, Amer NM (2023) miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses. Pathol-Res Pract 245:154439

Article  CAS  PubMed  Google Scholar 

El-Husseiny AA, Abdelmaksoud NM, Mageed SSA, Salman A, Zaki MB, El-Mahdy HA, Ismail A, Abd-Elmawla MA, El-Husseiny HM, Abulsoud AI (2023) miRNAs orchestration of salivary gland cancer-Particular emphasis on diagnosis, progression, and drug resistance. Pathol-Res Pract 248:154590

Article  CAS  PubMed  Google Scholar 

Eslami M, Khazeni S, Khanaghah XM, Asadi MH, Ansari MA, Garjan JH, Lotfalizadeh MH, Bayat M, Taghizadieh M, Taghavi SP (2023) MiRNA-related metastasis in oral cancer: moving and shaking. Cancer Cell Int 23:182

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng Y-H, Tsao C-J (2016) Emerging role of microRNA-21 in cancer. Biomed Rep 5:395–402

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng X, Luo Q, Wang H, Zhang H, Chen F (2018) MicroRNA-22 suppresses cell proliferation, migration and invasion in oral squamous cell carcinoma by targeting NLRP3. J Cell Physiol 233:6705–6713

Article  CAS  PubMed  Google Scholar 

Garajei A, Allameh A, Azadi M, Emami A, Atashbasteh M, Mostafavi M, Ghaderi B, Inchingolo F, Sadeghi M, Tadakamadla SK (2023) Evaluation of the expression levels of miR-21-5p and miR-429 genes in biopsy samples from patients with oral squamous cell carcinoma. Diagnostics 13:1244

Article  CAS  PubMed  PubMed Central  Google Scholar 

Geyer M, Geyer F, Reuning U, Klapproth S, Wolff K-D, Nieberler M (2024) CRISPR/Cas9-mediated knock out of ITGB6 in human OSCC cells reduced migration and proliferation ability. Head Face Med 20:37

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ghuwalewala S, Ghatak D, Das S, Roy S, Das P, Butti R, Gorain M, Nath S, Kundu GC, Roychoudhury S (2021) MiRNA-146a/AKT/β-catenin activation regulates cancer stem cell phenotype in oral squamous cell carcinoma by targeting CD24. Front Oncol 11:651692

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hosseini SA, Elahian F, Mirzaei SA (2024) Innovative genetic scissor strategies and their applications in cancer treatment and prevention: CRISPR modules and challenges. Int J Biol Macromol 279:1–8

Article  Google Scholar 

Huang F, Xin C, Lei K, Bai H, Li J, Chen Q (2020) Noncoding RNAs in oral premalignant disorders and oral squamous cell carcinoma. Cell Oncol 43:763–777

Article  CAS  Google Scholar 

Hussen BM, Rasul MF, Abdullah SR, Hidayat HJ, Faraj GSH, Ali FA, Salihi A, Baniahmad A, Ghafouri-Fard S, Rahman M (2023) Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges. Mil Med Res 10:32

CAS  PubMed  PubMed Central  Google Scholar 

Jameel ZI (2023) MicroRNA biogenesis, mechanisms of function, circulation and application role in human diseases. Int J Sci Res Biol Sci 10:71–80

Google Scholar 

Johnson DE, Burtness B, Leemans CR, Lui VWY, Bauman JE, Grandis JR (2020) Head and neck squamous cell carcinoma. Nat Rev Dis Primers 6:92

Article  PubMed  PubMed Central  Google Scholar 

Kao Y-Y, Chou C-H, Yeh L-Y, Chen Y-F, Chang K-W, Liu C-J, Chiang C-YF, Lin S-C (2019) MicroRNA miR-31 targets SIRT3 to disrupt mitochondrial activity and increase oxidative stress in oral carcinoma. Cancer Lett 456:40–48

Article  CAS  PubMed  Google Scholar 

Komatsu S, Kitai H, Suzuki HI (2023) Network regulation of microRNA biogenesis and target interaction. Cells 12:306

Article  CAS  PubMed  PubMed Central