The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells

Chung HK, McDonald B, Kaech SM. The architectural design of CD8 + T cell responses in acute and chronic infection: parallel structures with divergent fates. J Exp Med. 2021;218:e20201730.

Article  PubMed  PubMed Central  Google Scholar 

Sun L, Su Y, Jiao A, Wang X, Zhang B. T cells in health and disease. Sig Transduct Target Ther. 2023;8:235.

Article  Google Scholar 

Walter U, Santamaria P. CD8 + T cells in autoimmunity. Curr Opin Immunol. 2005;17:624–31.

Article  PubMed  Google Scholar 

Passerini L, Gregori S. Induction of Antigen-specific tolerance in T cell mediated diseases. Front Immunol. 2020;11:2194.

Article  PubMed  PubMed Central  Google Scholar 

Wang Z, Liu X, Cao F, Bellanti JA, Zhou J, Zheng SG. Prospects of the Use of Cell Therapy to Induce Immune Tolerance. Front Immunol. 2020;11:792.

Article  PubMed  PubMed Central  Google Scholar 

Djouad F, Bouffi C, Ghannam S, Noël D, Jorgensen C. Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat Rev Rheumatol. 2009;5:392–9.

Article  PubMed  Google Scholar 

Gao F, Chiu SM, Motan DAL, et al. Mesenchymal stem cells and immunomodulation: current status and future prospects. Cell Death Dis. 2016;7:e2062.

Article  PubMed  PubMed Central  Google Scholar 

Leyendecker A Jr, Pinheiro CCG, Amano MT, Bueno DF. The Use of Human mesenchymal stem cells as therapeutic agents for the in vivo treatment of Immune-Related diseases: a systematic review. Front Immunol. 2018;9:2056.

Article  PubMed  Google Scholar 

Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015;35:e00191.

Article  PubMed  PubMed Central  Google Scholar 

Müller L, Tunger A, Wobus M, et al. Immunomodulatory properties of mesenchymal stromal cells: an update. Front Cell Dev Biol. 2021;9:637725.

Article  PubMed  PubMed Central  Google Scholar 

Krampera M. Mesenchymal stromal cell ‘licensing’: a multistep process. Leukemia. 2011;25:1408–14.

Article  PubMed  Google Scholar 

Petrenko Y, Vackova I, Kekulova K, et al. A comparative analysis of multipotent mesenchymal stromal cells derived from different sources, with a focus on neuroregenerative potential. Sci Rep. 2020;10:4290.

Article  PubMed  PubMed Central  Google Scholar 

Jiang W, Xu J. Immune modulation by mesenchymal stem cells. Cell Prolif. 2020;53:e12712.

Article  PubMed  Google Scholar 

Chen X, Liu Q, Huang W, et al. Stanniocalcin-2 contributes to mesenchymal stromal cells attenuating murine contact hypersensitivity mainly via reducing CD8 + Tc1 cells. Cell Death Dis. 2018;9:548.

Article  PubMed  PubMed Central  Google Scholar 

Di Nicola M, Carlo-Stella C, Magni M, et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood. 2002;99:3838–43.

Article  PubMed  Google Scholar 

Krampera M, Glennie S, Dyson J, et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood. 2003;101:3722–9.

Article  PubMed  Google Scholar 

Krampera M, Cosmi L, Angeli R, et al. Role for Interferon-γ in the Immunomodulatory activity of human bone marrow mesenchymal stem cells. Stem Cells. 2006;24:386–98.

Article  PubMed  Google Scholar 

Ge W, Jiang J, Arp J, Liu W, Garcia B, Wang H. Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression. Transplantation. 2010;90:1312–20.

Article  PubMed  Google Scholar 

Chen Q-H, Wu F, Liu L, et al. Mesenchymal stem cells regulate the Th17/Treg cell balance partly through hepatocyte growth factor in vitro. Stem Cell Res Ther. 2020;11:91.

Article  PubMed  PubMed Central  Google Scholar 

Ghannam S, Pène J, Torcy-Moquet G, Jorgensen C, Yssel H. Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T Regulatory Cell phenotype. JI. 2010;185:302–12.

Google Scholar 

Malcherek G, Jin N, Hückelhoven AG, et al. Mesenchymal stromal cells inhibit proliferation of virus-specific CD8(+) T cells. Leukemia. 2014;28:2388–94.

Article  PubMed  Google Scholar 

Maccario R, Podesta M, Moretta A, et al. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4 + T-cell subsets expressing a regulatory/suppressive phenotype. Haematol. 2005;90:516–25.

Google Scholar 

Rozenberg A, Rezk A, Boivin M-N, et al. Human mesenchymal stem cells impact Th17 and Th1 responses through a prostaglandin E2 and myeloid-dependent mechanism: hMSC reciprocal modulation of Th1/Th17 responses. STEM CELLS Translational Med. 2016;5:1506–14.

Article  Google Scholar 

Wang Q, Sun B, Wang D, et al. Murine bone marrow mesenchymal stem cells cause mature dendritic cells to promote T-cell tolerance. Scand J Immunol. 2008;68:607–15.

Article  PubMed  Google Scholar 

Augello A, Tasso R, Negrini S, et al. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol. 2005;35:1482–90.

Article  PubMed  Google Scholar 

Chinnadurai R, Copland IB, Patel SR, Galipeau J. IDO-Independent suppression of T cell effector function by IFN-γ–Licensed human mesenchymal stromal cells. JI. 2014;192:1491–501.

Google Scholar 

Davies LC, Heldring N, Kadri N, Le Blanc K. Mesenchymal stromal cell secretion of programmed Death-1 Ligands regulates T cell mediated Immunosuppression. Stem Cells. 2017;35:766–76.

Article  PubMed  Google Scholar 

Luz-Crawford P, Noël D, Fernandez X, et al. Mesenchymal Stem Cells Repress Th17 Molecular Program through the PD-1 pathway. Unutmaz D, Ed. PLoS ONE. 2012;7:e45272.

Article  PubMed  PubMed Central  Google Scholar 

Sheng H, Wang Y, Jin Y, et al. A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res. 2008;18:846–57.

Article  PubMed  Google Scholar 

Zhao Y, Wang L, Jin Y, Shi S. Fas ligand regulates the Immunomodulatory properties of Dental Pulp Stem cells. J Dent Res. 2012;91:948–54.

Article  PubMed  PubMed Central  Google Scholar 

Akiyama K, Chen C, Wang D, et al. Mesenchymal-stem-cell-Induced Immunoregulation involves FAS-Ligand-/FAS-Mediated T cell apoptosis. Cell Stem Cell. 2012;10:544–55.

Article  PubMed  PubMed Central  Google Scholar 

English K, Ryan JM, Tobin L, Murphy MJ, Barry FP, Mahon BP. Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25(high) forkhead box P3 + regulatory T cells. Clin Exp Immunol. 2009;156:149–60.

Article  PubMed  PubMed Central  Google Scholar 

Bouffi C, Bony C, Courties G, Jorgensen C, Noël D. IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis. PLoS ONE. 2010;5:e14247.

Article  PubMed  PubMed Central  Google Scholar 

Huang F, Chen M, Chen W, et al. Human gingiva-derived mesenchymal stem cells inhibit Xeno-Graft-versus-host disease via CD39-CD73-Adenosine and IDO signals. Front Immunol. 2017;8:68.

Article  PubMed  PubMed Central  Google Scholar 

Su J, Chen X, Huang Y, et al. Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species. Cell Death Differ. 2014;21:388–96.

Article  PubMed  Google Scholar 

Guo L, Lai P, Wang Y, et al. Extracellular vesicles from mesenchymal stem cells prevent contact hypersensitivity through the suppression of Tc1 and Th1 cells and expansion of regulatory T cells. Int Immunopharmacol. 2019;74:105663.

留言 (0)

沒有登入
gif