Chung HK, McDonald B, Kaech SM. The architectural design of CD8 + T cell responses in acute and chronic infection: parallel structures with divergent fates. J Exp Med. 2021;218:e20201730.
Article PubMed PubMed Central Google Scholar
Sun L, Su Y, Jiao A, Wang X, Zhang B. T cells in health and disease. Sig Transduct Target Ther. 2023;8:235.
Walter U, Santamaria P. CD8 + T cells in autoimmunity. Curr Opin Immunol. 2005;17:624–31.
Passerini L, Gregori S. Induction of Antigen-specific tolerance in T cell mediated diseases. Front Immunol. 2020;11:2194.
Article PubMed PubMed Central Google Scholar
Wang Z, Liu X, Cao F, Bellanti JA, Zhou J, Zheng SG. Prospects of the Use of Cell Therapy to Induce Immune Tolerance. Front Immunol. 2020;11:792.
Article PubMed PubMed Central Google Scholar
Djouad F, Bouffi C, Ghannam S, Noël D, Jorgensen C. Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat Rev Rheumatol. 2009;5:392–9.
Gao F, Chiu SM, Motan DAL, et al. Mesenchymal stem cells and immunomodulation: current status and future prospects. Cell Death Dis. 2016;7:e2062.
Article PubMed PubMed Central Google Scholar
Leyendecker A Jr, Pinheiro CCG, Amano MT, Bueno DF. The Use of Human mesenchymal stem cells as therapeutic agents for the in vivo treatment of Immune-Related diseases: a systematic review. Front Immunol. 2018;9:2056.
Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015;35:e00191.
Article PubMed PubMed Central Google Scholar
Müller L, Tunger A, Wobus M, et al. Immunomodulatory properties of mesenchymal stromal cells: an update. Front Cell Dev Biol. 2021;9:637725.
Article PubMed PubMed Central Google Scholar
Krampera M. Mesenchymal stromal cell ‘licensing’: a multistep process. Leukemia. 2011;25:1408–14.
Petrenko Y, Vackova I, Kekulova K, et al. A comparative analysis of multipotent mesenchymal stromal cells derived from different sources, with a focus on neuroregenerative potential. Sci Rep. 2020;10:4290.
Article PubMed PubMed Central Google Scholar
Jiang W, Xu J. Immune modulation by mesenchymal stem cells. Cell Prolif. 2020;53:e12712.
Chen X, Liu Q, Huang W, et al. Stanniocalcin-2 contributes to mesenchymal stromal cells attenuating murine contact hypersensitivity mainly via reducing CD8 + Tc1 cells. Cell Death Dis. 2018;9:548.
Article PubMed PubMed Central Google Scholar
Di Nicola M, Carlo-Stella C, Magni M, et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood. 2002;99:3838–43.
Krampera M, Glennie S, Dyson J, et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood. 2003;101:3722–9.
Krampera M, Cosmi L, Angeli R, et al. Role for Interferon-γ in the Immunomodulatory activity of human bone marrow mesenchymal stem cells. Stem Cells. 2006;24:386–98.
Ge W, Jiang J, Arp J, Liu W, Garcia B, Wang H. Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression. Transplantation. 2010;90:1312–20.
Chen Q-H, Wu F, Liu L, et al. Mesenchymal stem cells regulate the Th17/Treg cell balance partly through hepatocyte growth factor in vitro. Stem Cell Res Ther. 2020;11:91.
Article PubMed PubMed Central Google Scholar
Ghannam S, Pène J, Torcy-Moquet G, Jorgensen C, Yssel H. Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T Regulatory Cell phenotype. JI. 2010;185:302–12.
Malcherek G, Jin N, Hückelhoven AG, et al. Mesenchymal stromal cells inhibit proliferation of virus-specific CD8(+) T cells. Leukemia. 2014;28:2388–94.
Maccario R, Podesta M, Moretta A, et al. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4 + T-cell subsets expressing a regulatory/suppressive phenotype. Haematol. 2005;90:516–25.
Rozenberg A, Rezk A, Boivin M-N, et al. Human mesenchymal stem cells impact Th17 and Th1 responses through a prostaglandin E2 and myeloid-dependent mechanism: hMSC reciprocal modulation of Th1/Th17 responses. STEM CELLS Translational Med. 2016;5:1506–14.
Wang Q, Sun B, Wang D, et al. Murine bone marrow mesenchymal stem cells cause mature dendritic cells to promote T-cell tolerance. Scand J Immunol. 2008;68:607–15.
Augello A, Tasso R, Negrini S, et al. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol. 2005;35:1482–90.
Chinnadurai R, Copland IB, Patel SR, Galipeau J. IDO-Independent suppression of T cell effector function by IFN-γ–Licensed human mesenchymal stromal cells. JI. 2014;192:1491–501.
Davies LC, Heldring N, Kadri N, Le Blanc K. Mesenchymal stromal cell secretion of programmed Death-1 Ligands regulates T cell mediated Immunosuppression. Stem Cells. 2017;35:766–76.
Luz-Crawford P, Noël D, Fernandez X, et al. Mesenchymal Stem Cells Repress Th17 Molecular Program through the PD-1 pathway. Unutmaz D, Ed. PLoS ONE. 2012;7:e45272.
Article PubMed PubMed Central Google Scholar
Sheng H, Wang Y, Jin Y, et al. A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res. 2008;18:846–57.
Zhao Y, Wang L, Jin Y, Shi S. Fas ligand regulates the Immunomodulatory properties of Dental Pulp Stem cells. J Dent Res. 2012;91:948–54.
Article PubMed PubMed Central Google Scholar
Akiyama K, Chen C, Wang D, et al. Mesenchymal-stem-cell-Induced Immunoregulation involves FAS-Ligand-/FAS-Mediated T cell apoptosis. Cell Stem Cell. 2012;10:544–55.
Article PubMed PubMed Central Google Scholar
English K, Ryan JM, Tobin L, Murphy MJ, Barry FP, Mahon BP. Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25(high) forkhead box P3 + regulatory T cells. Clin Exp Immunol. 2009;156:149–60.
Article PubMed PubMed Central Google Scholar
Bouffi C, Bony C, Courties G, Jorgensen C, Noël D. IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis. PLoS ONE. 2010;5:e14247.
Article PubMed PubMed Central Google Scholar
Huang F, Chen M, Chen W, et al. Human gingiva-derived mesenchymal stem cells inhibit Xeno-Graft-versus-host disease via CD39-CD73-Adenosine and IDO signals. Front Immunol. 2017;8:68.
Article PubMed PubMed Central Google Scholar
Su J, Chen X, Huang Y, et al. Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species. Cell Death Differ. 2014;21:388–96.
Guo L, Lai P, Wang Y, et al. Extracellular vesicles from mesenchymal stem cells prevent contact hypersensitivity through the suppression of Tc1 and Th1 cells and expansion of regulatory T cells. Int Immunopharmacol. 2019;74:105663.
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