Ferreri AJM, Govi S, Pileri SA, Savage KJ. Anaplastic large cell lymphoma, ALK-positive. Crit Rev Oncol Hematol. 2012;83:293–302.

Article  PubMed  Google Scholar 

Falini B, Pileri S, Zinzani PL, Carbone A, Zagonel V, Wolf-Peeters C, et al. ALK+ lymphoma: clinico-pathological findings and outcome. Blood. 1999;93:2697–706.

CAS  PubMed  Google Scholar 

Sharma GG, Mota I, Mologni L, Patrucco E, Gambacorti-Passerini C, Chiarle R. Tumor resistance against ALK targeted therapy-where it comes from and where it goes. Cancers (Basel). 2018;10:62.

Article  PubMed  Google Scholar 

Chiarle R, Voena C, Ambrogio C, Piva R, Inghirami G. The anaplastic lymphoma kinase in the pathogenesis of cancer. Nat Rev Cancer. 2008;8:11–23.

Article  CAS  PubMed  Google Scholar 

Prokoph N, Larose H, Lim MS, Burke GAA, Turner SD. Treatment options for paediatric anaplastic large cell lymphoma (ALCL): current standard and beyond. Cancers (Basel). 2018;10:99.

Article  PubMed  Google Scholar 

Savage KJ, Harris NL, Vose JM, Ullrich F, Jaffe ES, Connors JM, et al. ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project. Blood. 2008;111:5496–504.

Article  CAS  PubMed  Google Scholar 

Rigaud C, Knörr F, Brugières L, Woessmann W. Diagnosis and management of ALK-positive anaplastic large cell lymphoma in children and adolescents. Best Pr Res Clin Haematol. 2023;36:101444.

Article  CAS  Google Scholar 

Rusconi F, Piazza R, Vagge E, Gambacorti-Passerini C. Bosutinib: a review of preclinical and clinical studies in chronic myelogenous leukemia. Expert Opin Pharmacother. 2014;15:701–10.

Article  CAS  PubMed  Google Scholar 

Foyil KV, Bartlett NL. Brentuximab vedotin and crizotinib in anaplastic large-cell lymphoma. Cancer J. 2012;18:450–6.

Article  CAS  PubMed  Google Scholar 

Bossi E, Aroldi A, Brioschi FA, Steidl C, Baretta S, Renso R, et al. Phase two study of crizotinib in patients with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma relapsed/refractory to chemotherapy. Am J Hematol. 2020;95:E319–21.

Article  CAS  PubMed  Google Scholar 

Crescenzo R, Abate F, Lasorsa E, Tabbo F, Gaudiano M, Chiesa N, et al. Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma. Cancer Cell. 2015;27:516–32.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Larose H, Prokoph N, Matthews JD, Schlederer M, Högler S, Alsulami AF, et al. Whole exome sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target. Haematologica. 2021;106:1693–704.

Article  CAS  PubMed  Google Scholar 

Lobello C, Tichy B, Bystry V, Radova L, Filip D, Mraz M, et al. STAT3 and TP53 mutations associate with poor prognosis in anaplastic large cell lymphoma. Leukemia. 2021;35:1500–5.

Article  CAS  PubMed  Google Scholar 

Piazza R, Magistroni V, Pirola A, Redaelli S, Spinelli R, Galbiati M, et al. CEQer: a graphical tool for copy number and allelic imbalance detection from whole-exome sequencing data. PLoS One. 2013;8:e74825.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Takashimizu Y, Iiyoshi M. New parameter of roundness R: circularity corrected by aspect ratio. Prog Earth Planet Sci. 2016;3:2.

Article  Google Scholar 

Lausen J, Cho S, Liu S, Werner MH. The nuclear receptor co-repressor (N-CoR) utilizes repression domains I and III for interaction and co-repression with ETO. J Biol Chem. 2004;279:49281–8.

Article  CAS  PubMed  Google Scholar 

Arosio G, Sharma GG, Villa M, Mauri M, Crespiatico I, Fontana D, et al. Synergistic drug combinations prevent resistance in ALK+ anaplastic large cell lymphoma. Cancers (Basel). 2021;13:4422.

Article  CAS  PubMed  Google Scholar 

Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15:550.

Article  PubMed  PubMed Central  Google Scholar 

Wang J, Duncan D, Shi Z, Zhang B. WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res. 2013;41:W77–83.

Article  PubMed  PubMed Central  Google Scholar 

Ludwig KR, Schroll MM, Hummon AB. Comparison of in-solution, FASP, and S-Trap based digestion methods for bottom-up proteomic studies. J Proteome Res. 2018;17:2480–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pagani L, Chinello C, Risca G, Capitoli G, Criscuolo L, Lombardi A, et al. Plasma proteomic variables related to COVID-19 severity: an untargeted nLC-MS/MS investigation. Int J Mol Sci. 2023;24:3570.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Piazza R, Ramazzotti D, Spinelli R, Pirola A, De Sano L, Ferrari P, et al. OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes. Sci Rep. 2017;7:46290. 2017/04/08

Article  PubMed  Google Scholar 

Mologni L, Piazza R, Khandelwal P, Pirola A, Gambacorti-Passerini C. Somatic mutations identified at diagnosis by exome sequencing can predict response to imatinib in chronic phase chronic myeloid leukemia (CML) patients. Am J Hematol. 2017;92:E623–5.

Article  CAS  PubMed  Google Scholar 

Youssif C, Goldenbogen J, Hamoudi R, Carreras J, Viskaduraki M, Cui YX, et al. Genomic profiling of pediatric ALK-positive anaplastic large cell lymphoma: a Children’s Cancer and Leukaemia Group Study. Genes Chromosom Cancer. 2009;48:1018–26.

Article  CAS  PubMed  Google Scholar 

Fontana D, Crespiatico I, Crippa V, Malighetti F, Villa M, Angaroni F, et al. Evolutionary signatures of human cancers revealed via genomic analysis of over 35,000 patients. Nat Commun. 2023;14:5982.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Katoh M. Function and cancer genomics of FAT family genes (review). Int J Oncol. 2012;41:1913–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ptashkin RN, Ewalt MD, Jayakumaran G, Kiecka I, Bowman AS, Yao J, et al. Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing. Nat Commun. 2023;14:6895.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang X, Liu J, Liang X, Chen J, Hong J, Li L, et al. History and progression of Fat cadherins in health and disease. Onco Targets Ther. 2016;9:7337–43.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sharma P, Sheets K, Elankumaran S, Nain AS. The mechanistic influence of aligned nanofibers on cell shape, migration and blebbing dynamics of glioma cells. Integr Biol (Camb). 2013;5:1036–44.

Article  CAS  PubMed  Google Scholar 

Anand M, Lai R, Gelebart P. beta-catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Haematologica. 2010;96:253–61.

Article  PubMed  PubMed Central  Google Scholar 

Mologni L, Brussolo S, Ceccon M, Gambacorti-Passerini C. Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells. PLoS One. 2012;7:e51449.

Article  CAS