These authors contributed equally: Razia Rahman, Muhammed H. Rahaman.

These authors jointly supervised this work: Shudong Wang and Luke A. Selth.

Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia

Razia Rahman, Adrienne R. Hanson, Jianling Xie, Scott L. Townley, Raj Shrestha, Giles Best, Ganessan Kichenadasse, Simon J. Conn & Luke A. Selth

Drug Discovery and Development, Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia

Muhammed H. Rahaman, Ramin Hassankhani, Saiful Islam & Shudong Wang

Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia

Nicholas Choo, Gail P. Risbridger & Mitchell G. Lawrence

Flinders University, Freemasons Centre for Male Health and Wellbeing, Bedford Park, SA, Australia

Raj Shrestha & Luke A. Selth

Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia

Susanne Ramm & Kaylene J. Simpson

The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia

Susanne Ramm, Kaylene J. Simpson, Gail P. Risbridger, Renea A. Taylor & Mitchell G. Lawrence

Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, Australia

Kaylene J. Simpson

Peter MacCallum Cancer Centre, Melbourne, VIC, Australia

Gail P. Risbridger, Renea A. Taylor & Mitchell G. Lawrence

Cabrini Institute, Cabrini Health, Malvern, Melbourne, VIC, Australia

Gail P. Risbridger, Renea A. Taylor & Mitchell G. Lawrence

Melbourne Urological Research Alliance (MURAL), Monash Biomedicine Discovery Institute Cancer Program, Monash University, Clayton, VIC, Australia

Gail P. Risbridger, Renea A. Taylor & Mitchell G. Lawrence

South Australian Health and Medical Research Institute, Adelaide, SA, Australia

Margaret M. Centenera & Lisa M. Butler

Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia

Margaret M. Centenera, Lisa M. Butler, Wayne D. Tilley & Luke A. Selth

Beth Israel Deaconess Medical Center, Boston, MA, USA

Steven P. Balk

Department of Medical Oncology, Flinders Medical Centre, Southern Adelaide Local Health Network, Adelaide, SA, South Australia

Ganessan Kichenadasse

Biomedicine Discovery Institute Cancer Program, Department of Physiology, Monash University, Clayton, VIC, Australia

Renea A. Taylor

Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia

Wayne D. Tilley