Measuring carbohydrate recognition profile of lectins on live cells using liquid glycan array (LiGA)

Oyelaran, O. & Gildersleeve, J. C. Glycan arrays: recent advances and future challenges. Curr. Opin. Chem. Biol. 13, 406–413 (2009).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cobb, B. A. & Kasper, D. L. Coming of age: carbohydrates and immunity. Eur. J. Immunol. 35, 352–356 (2005).

Article  CAS  PubMed  Google Scholar 

Smith, B. A. H. & Bertozzi, C. R. The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans. Nat. Rev. Drug Discov. 20, 217–243 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blixt, O. et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc. Natl Acad. Sci. USA 101, 17033–17038 (2004).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Razi, N. & Varki, A. Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes. Proc. Natl Acad. Sci. USA 95, 7469–7474 (1998).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Collins, B. E. et al. Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact. Proc. Natl Acad. Sci. USA 101, 6104–6109 (2004).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kiessling, L. L. & Grim, J. C. Glycopolymer probes of signal transduction. Chem. Soc. Rev. 42, 4476–4491 (2013).

Article  CAS  PubMed  Google Scholar 

Frenz, T. et al. Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers. Eur. J. Pharm. Biopharm. 95, 13–17 (2015).

Article  CAS  PubMed  Google Scholar 

Alam, M. M. et al. Glycan-modified virus-like particles evoke T helper type 1-like immune responses. Acs Nano 15, 309–321 (2021).

Article  CAS  PubMed  Google Scholar 

Sojitra, M. et al. Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage. Nat. Chem. Biol. 17, 806–816 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tjhung, K. F. et al. Silent encoding of chemical post-translational modifications in phage-displayed libraries. J. Am. Chem. Soc. 138, 32–35 (2016).

Article  CAS  PubMed  Google Scholar 

Lin, C.-L. et al. Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arrays. Nat. Commun. 14, 5237 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thomas, B. et al. Application of biocatalysis to on-DNA carbohydrate library synthesis. ChemBioChem 18, 858–863 (2017).

Article  CAS  PubMed  Google Scholar 

Yan, M. et al. Next-generation glycan microarray enabled by DNA-coded glycan library and next-generation sequencing technology. Anal. Chem. 91, 9221–9228 (2019).

Article  CAS  PubMed  Google Scholar 

Kondengaden, S. M. et al. DNA encoded glycan libraries as a next-generation tool for the study of glycan–protein interactions. Preprint at bioRxiv https://doi.org/10.1101/2020.03.30.017012 (2020).

Schmidt, E. N. et al. Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket. Nat. Commun. 14, 2327 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Crocker, P. R., Paulson, J. C. & Varki, A. Siglecs and their roles in the immune system. Nat. Rev. Immunol. 7, 255–266 (2007).

Article  CAS  PubMed  Google Scholar 

Nicoll, G. et al. Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via Siglec-7-dependent and -independent mechanisms. Eur. J. Immunol. 33, 1642–1648 (2003).

Article  CAS  PubMed  Google Scholar 

Jandus, C. et al. Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. J. Clin. Invest. 124, 1810–1820 (2014).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shenoy, G. N. et al. Sialic acid-dependent inhibition of T cells by exosomal ganglioside GD3 in ovarian tumor microenvironments. J. Immunol. 201, 3750–3758 (2018).

Article  CAS  PubMed  Google Scholar 

Laubli, H., Nalle, S. C. & Maslyar, D. Targeting the Siglec–sialic acid immune axis in cancer: current and future approaches. Cancer Immunol. Res. 10, 1423–1432 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gray, M. A. et al. Targeted glycan degradation potentiates the anticancer immune response in vivo. Nat. Chem. Biol. 16, 1376–1384 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Gonzalez-Gil, A., Li, T. A., Kim, J. & Schnaar, R. L. Human sialoglycan ligands for immune inhibitory Siglecs. Mol. Asp. Med. 90, 101110 (2023).

Article  CAS  Google Scholar 

Jung, J. et al. Carbohydrate sulfation as a mechanism for fine-tuning Siglec ligands. ACS Chem. Biol. 16, 2673–2689 (2021).

Article  CAS  PubMed  Google Scholar 

Feinberg, H., Castelli, R., Drickamer, K., Seeberger, P. H. & Weis, W. I. Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins. J. Biol. Chem. 282, 4202–4209 (2007).

Article  CAS  PubMed  Google Scholar 

Matochko, W. L., Cory Li, S., Tang, S. K. Y. & Derda, R. Prospective identification of parasitic sequences in phage display screens. Nucleic Acids Res. 42, 1784–1798 (2014).

Article  CAS  PubMed  Google Scholar 

Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139–140 (2010).

Article  CAS  PubMed  Google Scholar 

Chen, Y., Lun, A. & Smyth, G. From reads to genes to pathways: differential expression analysis of RNA-seq experiments using Rsubread and the edgeR quasi-likelihood pipeline. F1000Research 5, 1438 (2016).

PubMed  PubMed Central  Google Scholar 

Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate—a practical and powerful approach to multiple testing. J. R. Stat. Soc. B 57, 289–300 (1995).

Article  Google Scholar 

Robinson, M. D. & Oshlack, A. A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol. 11, R25 (2010).

Article  PubMed  PubMed Central  Google Scholar 

Rodrigues, E. et al. A versatile soluble Siglec scaffold for sensitive and quantitative detection of glycan ligands. Nat. Commun. 11, 5091 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

McCord, K. A. et al. Dissecting the ability of Siglecs to antagonize Fcγ receptors. ACS Cent. Sci. 10, 315–330 (2024).

Article  CAS 

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