Kellum, J. A., R. Bellomo, and C. Ronco. 2012. Kidney attack. JAMA 307 (21): 2265–2266.

Article  PubMed  Google Scholar 

Bedford, M., P. E. Stevens, T. W. Wheeler, and C. K. Farmer. 2014. What is the real impact of acute kidney injury. BMC Nephrology 15:95.

Article  PubMed  PubMed Central  Google Scholar 

Pickkers, P., M. Ostermann, M. Joannidis, et al. 2017. The intensive care medicine agenda on acute kidney injury. Intensive Care Medicine 43 (9): 1198–1209.

Article  PubMed  PubMed Central  Google Scholar 

Murugan, R., V. Karajala-Subramanyam, M. Lee, et al. 2010. Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney International 77 (6): 527–535.

Article  PubMed  Google Scholar 

Vincent, J. L., Y. Sakr, C. L. Sprung, et al. 2006. Sepsis in European intensive care units: Results of the SOAP study. Critical Care Medicine 34 (2): 344–353.

Article  PubMed  Google Scholar 

Langenberg, C., L. Wan, M. Egi, C. N. May, and R. Bellomo. 2006. Renal blood flow in experimental septic acute renal failure. Kidney International 69 (11): 1996–2002.

Article  PubMed  Google Scholar 

Ghosh, C. C., S. David, R. Zhang, et al. 2016. Gene control of tyrosine kinase TIE2 and vascular manifestations of infections. Proceedings of the National Academy of Sciences of the United States of America 113 (9): 2472-7.

Elias, E. E., B. Lyons, and D. A. Muruve. 2023. Gasdermins and pyroptosis in the kidney. Nature Reviews Nephrology 19 (5): 337–350.

Article  PubMed  Google Scholar 

Ronco, C., R. Bellomo, and J. A. Kellum. 2019. Acute kidney injury. Lancet 394 (10212): 1949–1964.

Article  PubMed  Google Scholar 

Zhang, Z., X. Shao, N. Jiang, et al. 2018. Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury. Cell Death & Disease 9 (10): 983.

Article  Google Scholar 

Inciarte-Mundo, J., B. Frade-Sosa, and R. Sanmartí. 2022. From bench to bedside: Calprotectin (S100A8/S100A9) as a biomarker in rheumatoid arthritis. Frontiers in Immunology 13:1001025.

Article  PubMed  PubMed Central  Google Scholar 

Mangan, M., E. J. Olhava, W. R. Roush, H. M. Seidel, G. D. Glick, and E. Latz. 2018. Targeting the NLRP3 inflammasome in inflammatory diseases. Nature Reviews Drug Discovery 17 (8): 588–606.

Article  PubMed  Google Scholar 

Fan, H., J. W. Le, M. Sun, and J. H. Zhu. 2021. Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis. Iranian Journal of Basic Medical Sciences 24 (5): 675–681.

PubMed  PubMed Central  Google Scholar 

Li, Y., P. Zhai, Y. Zheng, J. Zhang, J. A. Kellum, and Z. Peng. 2020. Csf2 attenuated sepsis-induced acute kidney injury by promoting alternative macrophage transition. Frontiers in Immunology 11: 1415.

Article  PubMed  PubMed Central  Google Scholar 

Ritchie, M. E., B. Phipson, D. Wu, et al. 2015. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Research 43 (7): e47.

Article  PubMed  PubMed Central  Google Scholar 

Yu, G., L. G. Wang, Y. Han, and Q. Y. He. 2012. clusterProfiler: An R package for comparing biological themes among gene clusters. OMICS: A Journal of Integrative Biology 16 (5): 284–287.

Article  PubMed  Google Scholar 

2015. Gene ontology consortium: going forward. Nucleic Acids Research 43 (Database issue): D1049–56. https://doi.org/10.1093/nar/gku1179

Kanehisa, M., Y. Sato, M. Kawashima, M. Furumichi, and M. Tanabe. 2016. KEGG as a reference resource for gene and protein annotation. Nucleic Acids Research 44 (D1): D457–D462.

Article  PubMed  Google Scholar 

Villanueva, R. A. M., and Z. J. Chen. 2019. ggplot2: elegant graphics for data analysis (2nd ed.). Measurement Interdisciplinary Research & Perspectives 17 (3): 160–167.

Article  Google Scholar 

Wu, T., E. Hu, S. Xu, et al. 2021. clusterProfiler 4.0: A universal enrichment tool for interpreting omics data. Innovation (Camb) 2 (3): 100141.

PubMed  Google Scholar 

Shannon, P., A. Markiel, O. Ozier, et al. 2003. Cytoscape: A software environment for integrated models of biomolecular interaction networks. Genome Research 13 (11): 2498–2504.

Article  PubMed  PubMed Central  Google Scholar 

Flameng, W., M. Borgers, W. Daenen, and G. Stalpaert. 1980. Ultrastructural and cytochemical correlates of myocardial protection by cardiac hypothermia in man. Journal of Thoracic and Cardiovascular Surgery 79 (3): 413–424.

Article  PubMed  Google Scholar 

Mellor, L. F., N. Gago-Lopez, L. Bakiri, et al. 2022. Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease. Annals of the Rheumatic Diseases 81 (10): 1400–1408.

Article  PubMed  Google Scholar 

Yao, Z., B. Zhang, G. Niu, et al. 2022. Neutrophil Infiltration characterized by upregulation of S100A8, S100A9, S100A12 and CXCR2 is associated with the co-occurrence of Crohn’s disease and peripheral artery disease. Frontiers in Immunology 13: 896645.

Article  PubMed  PubMed Central  Google Scholar 

Tan, L., X. Li, H. Qin, et al. 2024. Identified S100A9 as a target for diagnosis and treatment of ulcerative colitis by bioinformatics analysis. Science and Reports 14 (1): 5517.

Article  Google Scholar 

Fleischmann, C., A. Scherag, N.K. Adhikari, et al. 2016. Assessment of global incidence and mortality of hospital-treated sepsis. Current estimates and limitations. American Journal of Respiratory and Critical Care Medicine 193 (3): 259–72.

Article  PubMed  Google Scholar 

Hoste, E. A., S. M. Bagshaw, R. Bellomo, et al. 2015. Epidemiology of acute kidney injury in critically ill patients: The multinational AKI-EPI study. Intensive Care Medicine 41 (8): 1411–1423.

Article  PubMed  Google Scholar 

Uchino, S., J. A. Kellum, R. Bellomo, et al. 2005. Acute renal failure in critically ill patients: A multinational, multicenter study. JAMA 294 (7): 813–818.

Article  PubMed  Google Scholar 

Cohen, J., J. L. Vincent, N. K. Adhikari, et al. 2015. Sepsis: A roadmap for future research. The Lancet Infectious Diseases 15 (5): 581–614.

Article  PubMed  Google Scholar 

Jiang, N., R. Huang, J. Zhang, et al. 2022. TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury. The FASEB Journal 36 (4): e22228.

Article  PubMed  Google Scholar 

Ferrè, S., Y. Deng, S. C. Huen, et al. 2019. Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation. Kidney International 96 (6): 1359–1373.

Article  PubMed  PubMed Central  Google Scholar 

Sun, J., X. Ge, Y. Wang, L. Niu, L. Tang, and S. Pan. 2022. USF2 knockdown downregulates THBS1 to inhibit the TGF-β signaling pathway and reduce pyroptosis in sepsis-induced acute kidney injury. Pharmacological Research 176: 105962.

Article  PubMed  Google Scholar 

Porter, A. W., D. N. Nguyen, D. R. Clayton, et al. 2022. The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice. JCI Insight 7 (5): e151869.

Article  PubMed  PubMed Central  Google Scholar 

Linkermann, A., G. Chen, G. Dong, U. Kunzendorf, S. Krautwald, and Z. Dong. 2014. Regulated cell death in AKI. Journal of the American Society of Nephrology 25 (12): 2689–2701.

Article  PubMed  PubMed Central  Google Scholar 

Kaushal, G. P., and S. V. Shah. 2016. Autophagy in acute kidney injury. Kidney International 89 (4): 779–791.

Article  PubMed  PubMed Central  Google Scholar 

Nežić, L., R. Škrbić, L. Amidžić, et al. 2020. Protective effects of simvastatin on endotoxin-induced acute kidney injury through activation of tubular epithelial cells’ survival and hindering cytochrome c-mediated apoptosis. International Journal of Molecular Sciences 21 (19): 7236.

Article  PubMed  PubMed Central  Google Scholar 

Galluzzi, L., I. Vitale, S. A. Aaronson, et al. 2018. Molecular mechanisms of cell death: Recommendation