Aquaporin-1 Facilitates Macrophage M1 Polarization by Enhancing Glycolysis Through the Activation of HIF1α in Lipopolysaccharide-Induced Acute Kidney Injury

Poston, J.T., and J.L. Koyner. 2019. Sepsis associated acute kidney injury. BMJ 364: k4891.

Article  PubMed  PubMed Central  Google Scholar 

Doi, K., A. Leelahavanichkul, P.S. Yuen, and R.A. Star. 2009. Animal models of sepsis and sepsis-induced kidney injury. Journal of Clinical Investigation 119: 2868–2878.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zarbock, A., M.K. Nadim, P. Pickkers, H. Gomez, S. Bell, M. Joannidis, K. Kashani, J.L. Koyner, N. Pannu, M. Meersch, T. Reis, T. Rimmelé, S.M. Bagshaw, R. Bellomo, V. Cantaluppi, A. Deep, S. De Rosa, X. Perez-Fernandez, F. Husain-Syed, S.L. Kane-Gill, Y. Kelly, R.L. Mehta, P.T. Murray, M. Ostermann, J. Prowle, Z. Ricci, E.J. See, A. Schneider, D.E. Soranno, A. Tolwani, G. Villa, C. Ronco, and L.G. Forni. 2023. Sepsis-associated acute kidney injury: Consensus report of the 28th Acute Disease Quality Initiative workgroup. Nature Reviews. Nephrology 19: 401–417.

Article  PubMed  Google Scholar 

Shapouri-Moghaddam, A., S. Mohammadian, H. Vazini, M. Taghadosi, S.A. Esmaeili, F. Mardani, B. Seifi, A. Mohammadi, J.T. Afshari, and A. Sahebkar. 2018. Macrophage plasticity, polarization, and function in health and disease. Journal of Cellular Physiology 233: 6425–6440.

Article  CAS  PubMed  Google Scholar 

Chou, C.L., M.A. Knepper, A.N. Hoek, D. Brown, B. Yang, T. Ma, and A.S. Verkman. 1999. Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice. Journal of Clinical Investigation 103: 491–496.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nielsen, S., J. Frøkiaer, D. Marples, T.H. Kwon, P. Agre, and M.A. Knepper. 2002. Aquaporins in the kidney: From molecules to medicine. Physiological Reviews 82: 205–244.

Article  CAS  PubMed  Google Scholar 

Hua, Y., X. Ying, Y. Qian, H. Liu, Y. Lan, A. Xie, X. Zhu. 2019. Physiological and pathological impact of AQP1 knockout in mice. Bioscience Reports 39. https://doi.org/10.1042/BSR20182303

Chen, M., Y. Li, L. Xiao, G. Dai, P. Lu, Y. Wang, and Y. Rui. 2020. AQP1 modulates tendon stem/progenitor cells senescence during tendon aging. Cell Death and Disease 11: 193.

Article  PubMed  PubMed Central  Google Scholar 

Galán-Cobo, A., R. Ramírez-Lorca, J.J. Toledo-Aral, and M. Echevarría. 2016. Aquaporin-1 plays important role in proliferation by affecting cell cycle progression. Journal of Cellular Physiology 231: 243–256.

Article  PubMed  Google Scholar 

Li, B., C. Liu, K. Tang, X. Dong, L. Xue, G. Su, W. Zhang, and Y. Jin. 2019. Aquaporin-1 attenuates macrophage-mediated inflammatory responses by inhibiting p38 mitogen-activated protein kinase activation in lipopolysaccharide-induced acute kidney injury. Inflammation Research 68: 1035–1047.

Article  PubMed  PubMed Central  Google Scholar 

Lv, W., L. Liang, D. Liu, C. Li, L. Jia, and Y. Jin. 2023. Aquaporin 1 Facilitates Ferroptosis, M1 Polarization, Mitochondrial Dysfunction, and Autophagy Damage on Lipopolysaccharide-Induced Macrophage Through Down-Regulation of P53 Signaling Pathway. DNA and Cell Biology 42: 456–480.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maltaneri, R.E., A. Schiappacasse, M.E. Chamorro, A.B. Nesse, and D.C. Vittori. 2020. Aquaporin-1 plays a key role in erythropoietin-induced endothelial cell migration. Biochimica et Biophysica Acta, Molecular Cell Research 1867: 118569.

Article  CAS  PubMed  Google Scholar 

Semenza, G.L. 2001. Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology. Trends in Molecular Medicine 7: 345–350.

Article  CAS  PubMed  Google Scholar 

Wang, T., H. Liu, G. Lian, S.Y. Zhang, X. Wang, and C. Jiang. 2017. HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages. Mediators of Inflammation 2017: 9029327.

Article  PubMed  PubMed Central  Google Scholar 

Hill, P., D. Shukla, M.G. Tran, J. Aragones, H.T. Cook, P. Carmeliet, and P.H. Maxwell. 2008. Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury. Journal of the American Society of Nephrology 19: 39–46.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Weidemann, A., W.M. Bernhardt, B. Klanke, C. Daniel, B. Buchholz, V. Câmpean, K. Amann, C. Warnecke, M.S. Wiesener, K.U. Eckardt, and C. Willam. 2008. HIF activation protects from acute kidney injury. Journal of the American Society of Nephrology 19: 486–494.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang, G.L., B.H. Jiang, E.A. Rue, and G.L. Semenza. 1995. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proceedings of the National Academy of Sciences of the United States of America 92: 5510–5514.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee, J.W., S.H. Bae, J.W. Jeong, S.H. Kim, and K.W. Kim. 2004. Hypoxia-inducible factor (HIF-1)alpha: Its protein stability and biological functions. Experimental & Molecular Medicine 36: 1–12.

Article  Google Scholar 

Dang, C.P., and A. Leelahavanichkul. 2020. Over-expression of miR-223 induces M2 macrophage through glycolysis alteration and attenuates LPS-induced sepsis mouse model, the cell-based therapy in sepsis. PLoS ONE 15: e0236038.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Corcoran, S.E., and L.A. O’Neill. 2016. HIF1α and metabolic reprogramming in inflammation. Journal of Clinical Investigation 126: 3699–3707.

Article  PubMed  PubMed Central  Google Scholar 

Simone, L., C.D. Gargano, F. Pisani, A. Cibelli, M.G. Mola, A. Frigeri, M. Svelto, and G.P. Nicchia. 2018. Aquaporin-1 inhibition reduces metastatic formation in a mouse model of melanoma. Journal of Cellular and Molecular Medicine 22: 904–912.

Article  CAS  PubMed  Google Scholar 

Keskinidou, C., N.S. Lotsios, A.G. Vassiliou, I. Dimopoulou, A. Kotanidou, and S.E. Orfanos. 2022. The Interplay between Aquaporin-1 and the Hypoxia-Inducible Factor 1α in a Lipopolysaccharide-Induced Lung Injury Model in Human Pulmonary Microvascular Endothelial Cells. International Journal of Molecular Sciences 23: 10588.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, C., B. Li, K. Tang, X. Dong, L. Xue, G. Su, and Y. Jin. 2020. Aquaporin 1 alleviates acute kidney injury via PI3K-mediated macrophage M2 polarization. Inflammation Research 69: 509–521.

Article  CAS  PubMed  Google Scholar 

Lv, W., L. Xue, L. Liang, D. Liu, C. Li, J. Liao, and Y. Jin. 2023. Endotoxin induced acute kidney injury modulates expression of AQP1, P53 and P21 in rat kidney, heart, lung and small intestine. PLoS ONE 18: e0288507.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Han, H.I., L.B. Skvarca, E.B. Espiritu, A.J. Davidson, and N.A. Hukriede. 2019. The role of macrophages during acute kidney injury: Destruction and repair. Pediatric Nephrology 34: 561–569.

Article  PubMed  Google Scholar 

Li, Z., S. Lu, and X. Li. 2021. The role of metabolic reprogramming in tubular epithelial cells during the progression of acute kidney injury. Cellular and Molecular Life Sciences 78: 5731–5741.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao, L., Y. Hao, S. Tang, X. Han, R. Li, and X. Zhou. 2023. Energy metabolic reprogramming regulates programmed cell death of renal tubular epithelial cells and might serve as a new therapeutic target for acute kidney injury. Front Cell Dev Biol 11: 1276217.

Article  PubMed  PubMed Central  Google Scholar 

Lin, S., Y. Li, D. Wang, C. Huang, D. Marino, O. Bollt, C. Wu, M.D. Taylor, W. Li, G.M. DeNicola, J. Hao, P.K. Singh, and S. Yang. 2021. Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression. Cancer Letters 518: 230–242.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shan, Xie, and Xu. Xingxin. 2020. The Role of PKM2-Regulated Glycolysis in Macrophages in Inflammation of Diabetic Nephropathy. Journal of the Third Military Medical University. 42: 2394–2402.

Google Scholar 

Zhu Pei, Li Dong, and Yan Dongmei. 2018. Research Progress on HIF-1α Regulation of Macrophage Glycolysis and Polarization. In The 13th National Immunology Academic Conference, 1 Shanghai, China.

Lin, S., P. Jin, C. Shao, W. Lu, Q. Xiang, Z. Jiang, Y. Zhang, and J. Bian. 2020. Lidocaine attenuates lipopolysaccharide-induced inflammatory responses and protects against endotoxemia in mice by suppressing HIF1α-induced glycolysis. Internation

留言 (0)

沒有登入
gif