Zhong, Z., et al. 2021. Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis. Progress in Retinal and Eye Research 80: 100866.

Article  CAS  PubMed  Google Scholar 

Bertrand, P.J., et al. 2021. Quality of life in patients with uveitis: Data from the ULISSE study (Uveitis: CLInical and medico-economic evaluation of a Standardised Strategy for the Etiological diagnosis). The British Journal of Ophthalmology 105 (7): 935–940.

Article  PubMed  Google Scholar 

Krishna, U., et al. 2017. Uveitis: A sight-threatening disease which can impact all systems. Postgraduate Medical Journal 93 (1106): 766–773.

Article  PubMed  Google Scholar 

Caspi, R.R. 2010. A look at autoimmunity and inflammation in the eye. The Journal of Clinical Investigation 120 (9): 3073–3083.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khera, T.K., et al. 2012. Tumour necrosis factor-mediated macrophage activation in the target organ is critical for clinical manifestation of uveitis. Clinical and Experimental Immunology 168 (2): 165–177.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hirahara, L., et al. 2022. The Roles of Monocytes and Macrophages in Behçet’s Disease With Focus on M1 and M2 Polarization. Frontiers in Immunology 13: 852297.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Okunuki, Y., et al. 2019. Retinal microglia initiate neuroinflammation in ocular autoimmunity. Proceedings of the National Academy of Sciences of the United States of America 116 (20): 9989–9998.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang, C., et al. 2002. Progranulin Suppressed Autoimmune Uveitis and Autoimmune Neuroinflammation by Inhibiting Th1/Th17 Cells and Promoting Treg Cells and M2 Macrophages. Neurology(R) Neuroimmunology & Neuroinflammation. 9(2). https://doi.org/10.1212/NXI.0000000000001133

Karlstetter, M., et al. 2015. Retinal microglia: Just bystander or target for therapy? Progress in Retinal and Eye Research 45: 30–57.

Article  PubMed  Google Scholar 

Chai, M., et al. 2022. Molecular Mechanism of the Protective Effects of M2 Microglia on Neurons: A Review Focused on Exosomes and Secretory Proteins. Neurochemical Research 47 (12): 3556–3564.

Article  CAS  PubMed  Google Scholar 

Boström, P., et al. 2012. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481 (7382): 463–468.

Article  PubMed  PubMed Central  Google Scholar 

Madhu, L.N., Y. Somayaji, and A.K. Shetty. 2022. Promise of irisin to attenuate cognitive dysfunction in aging and Alzheimer’s disease. Ageing Research Reviews 78: 101637.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Peng, J., et al. 2017. Irisin protects against neuronal injury induced by oxygen-glucose deprivation in part depends on the inhibition of ROS-NLRP3 inflammatory signaling pathway. Molecular Immunology 91: 185–194.

Article  CAS  PubMed  Google Scholar 

Zhu, X., et al. 2021. Irisin deficiency disturbs bone metabolism. Journal of Cellular Physiology 236 (1): 664–676.

Article  CAS  PubMed  Google Scholar 

Zhu, D., et al. 2015. Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses. Journal of Molecular and Cellular Cardiology 87: 138–147.

Article  CAS  PubMed  Google Scholar 

Wang, T., et al. 2023. FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction. International Journal of Molecular Sciences. 24 (4): 4159.

Article  CAS  PubMed  PubMed Central  Google Scholar 

1990. Criteria for diagnosis of Behçet’s disease. International Study Group for Behçet’s Disease. Lancet 335 (8697): 1078–80. PMID: 1970380.

Yang, P., et al. 2018. Development and Evaluation of Diagnostic Criteria for Vogt-Koyanagi-Harada Disease. JAMA Ophthalmology 136 (9): 1025–1031.

Article  PubMed  PubMed Central  Google Scholar 

Jabs, D.A., R.B. Nussenblatt, and J.T. Rosenbaum. 2005. Standardization of uveitis nomenclature for reporting clinical data Results of the First International Workshop. American Journal of Ophthalmology 140 (3): 509–16.

Article  PubMed  Google Scholar 

Mattapallil, M.J., et al. 2015. Characterization of a New Epitope of IRBP That Induces Moderate to Severe Uveoretinitis in Mice With H-2b Haplotype. Investigative Ophthalmology & Visual Science 56 (9): 5439–5449.

Article  CAS  Google Scholar 

Li, X., et al. 2022. The Changes of Irisin and Inflammatory Cytokines in the Age-Related Macular Degeneration and Retinal Vein Occlusion. Frontiers in Endocrinology 13: 861757.

Article  PubMed  PubMed Central  Google Scholar 

Ravesloot-Chávez, M.M., E. Van Dis, and S.A. Stanley. 2021. Mycobacterium tuberculosisThe Innate Immune Response to Infection. Annual Review of Immunology 39: 611–637.

Article  PubMed  Google Scholar 

Slate-Romano, J.J., N. Yano, and T.C. Zhao. 2022. Irisin reduces inflammatory signaling pathways in inflammation-mediated metabolic syndrome. Molecular and Cellular Endocrinology 552: 111676.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou, J., et al. 2020. A combination of inhibiting microglia activity and remodeling gut microenvironment suppresses the development and progression of experimental autoimmune uveitis. Biochemical Pharmacology 180: 114108.

Article  CAS  PubMed  Google Scholar 

Wang, Y., et al. 2022. Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice. Journal of Neuroinflammation 19 (1): 82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gao, J., et al. 2022. Panax notoginseng saponins alleviates inflammation induced by microglial activation and protects against ischemic brain injury via inhibiting HIF-1α/PKM2/STAT3 signaling. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 155: 13479.

Google Scholar 

Kim, S.R., et al. 2022. Epigallocatechin Gallate Protects against Hypoxia-Induced Inflammation in Microglia via NF-κB Suppression and Nrf-2/HO-1 Activation. International Journal of Molecular Sciences 23 (7): 4004.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cui, Z., et al. 2023. Intermittent hypoxia inhibits anti-tumor immune response via regulating PD-L1 expression in lung cancer cells and tumor-associated macrophages. International Immunopharmacology 122: 110652.

Article  CAS  PubMed  Google Scholar