Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia development

Zhang P. Decidual vasculopathy and spiral artery remodeling revisited II: relations to trophoblastic dependent and independent vascular transformation. J Maternal-Fetal Neonatal Med. 2020;1–7. https://doi.org/10.1080/14767058.2020.1718646.

Mori M, Bogdan A, Balassa T, Csabai T, Szekeres-Bartho J. The decidua-the maternal bed embracing the embryo-maintains the pregnancy. Semin Immunopathol. 2016;38:635–49. https://doi.org/10.1007/s00281-016-0574-0.

Article  PubMed  PubMed Central  Google Scholar 

Wu HM, Chen LH, Hsu LT, Lai CH. Immune Tolerance of embryo implantation and pregnancy: the role of human decidual stromal cell- and embryonic-derived extracellular vesicles. Int J Mol Sci. 2022;23. https://doi.org/10.3390/ijms232113382.

Vento-Tormo R, Efremova M, Botting RA, Turco MY, Vento-Tormo M, Meyer KB, Park JE, Stephenson E, Polański K, Goncalves A, et al. Single-cell reconstruction of the early maternal-fetal interface in humans. Nature. 2018;563:347–53. https://doi.org/10.1038/s41586-018-0698-6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Staff AC, Fjeldstad HE, Fosheim IK, Moe K, Turowski G, Johnsen GM, Alnaes-Katjavivi P, Sugulle M. Failure of physiological transformation and spiral artery atherosis: their roles in preeclampsia. Am J Obstet Gynecol. 2022;226:S895–906. https://doi.org/10.1016/j.ajog.2020.09.026.

Article  CAS  PubMed  Google Scholar 

Du L, Deng W, Zeng S, Xu P, Huang L, Liang Y, Wang Y, Xu H, Tang J, Bi S, et al. Single-cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion. Cell Prolif. 2021;54:e13125. https://doi.org/10.1111/cpr.13125.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Audette MC, Kingdom JC. Screening for fetal growth restriction and placental insufficiency. Semin Fetal Neonatal Med. 2018;23:119–25. https://doi.org/10.1016/j.siny.2017.11.004.

Article  PubMed  Google Scholar 

Levine RJ, Maynard SE, Qian C, Lim K-H, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, et al. Circulating angiogenic factors and the risk of Preeclampsia. N Engl J Med. 2004;350:672–83. https://doi.org/10.1056/NEJMoa031884.

Article  CAS  PubMed  Google Scholar 

Rana S, Lemoine E, Granger JP, Karumanchi SA, Preeclampsia. Pathophysiology, challenges, and perspectives. Circ Res. 2019;124:1094–112. https://doi.org/10.1161/circresaha.118.313276.

Article  CAS  PubMed  Google Scholar 

Conrad KP, Rabaglino MB, Post Uiterweer ED. Emerging role for dysregulated decidualization in the genesis of preeclampsia. Placenta. 2017;60:119–29. https://doi.org/10.1016/j.placenta.2017.06.005.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Albrecht ED, Babischkin JS, Aberdeen GW, Burch MG, Pepe GJ. Maternal systemic vascular dysfunction in a primate model of defective uterine spiral artery remodeling. Am J Physiol Heart Circ Physiol. 2021;320:H1712–23. https://doi.org/10.1152/ajpheart.00613.2020.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu P, Haththotuwa R, Kwok CS, Babu A, Kotronias RA, Rushton C, Zaman A, Fryer AA, Kadam U, Chew-Graham CA, et al. Preeclampsia and Future Cardiovascular Health: a systematic review and Meta-analysis. Circ Cardiovasc Qual Outcomes. 2017;10. https://doi.org/10.1161/circoutcomes.116.003497.

Khan B, Allah Yar R, Khakwani AK, Karim S, Arslan Ali H. Preeclampsia Incidence and its maternal and neonatal outcomes with Associated Risk factors. Cureus. 2022;14:e31143. https://doi.org/10.7759/cureus.31143.

Article  PubMed  PubMed Central  Google Scholar 

Garrido-Gómez T, Castillo-Marco N, Cordero T, Simón C. Decidualization resistance in the origin of preeclampsia. Am J Obstet Gynecol. 2022;226:S886–94. https://doi.org/10.1016/j.ajog.2020.09.039.

Article  CAS  PubMed  Google Scholar 

Garrido-Gomez T, Quiñonero A, Dominguez F, Rubert L, Perales A, Hajjar KA, Simon C. Preeclampsia: a defect in decidualization is associated with deficiency of annexin A2. Am J Obstet Gynecol. 2020;222:376e371. 376.e317.

Article  Google Scholar 

Garrido-Gomez T, Castillo-Marco N, Clemente-Ciscar M, Cordero T, Muñoz-Blat I, Amadoz A, Jimenez-Almazan J, Monfort-Ortiz R, Climent R, Perales-Marin A, et al. Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia. Elife. 2021;10. https://doi.org/10.7554/eLife.70753.

Yang M, Li H, Rong M, Zhang H, Hou L, Zhang C. Dysregulated GLUT1 may be involved in the pathogenesis of preeclampsia by impairing decidualization. Mol Cell Endocrinol. 2022;540:111509. https://doi.org/10.1016/j.mce.2021.111509.

Article  CAS  PubMed  Google Scholar 

Stevens DU, de Nobrega Teixeira JA, Spaanderman MEA, Bulten J, van Vugt JMG, Al-Nasiry. Understanding decidual vasculopathy and the link to preeclampsia: a review. Placenta. 2020;97:95–100. https://doi.org/10.1016/j.placenta.2020.06.020.

Article  CAS  PubMed  Google Scholar 

Ma Q, Beal JR, Bhurke A, Kannan A, Yu J, Taylor RN, Bagchi IC, Bagchi MK. Extracellular vesicles secreted by human uterine stromal cells regulate decidualization, angiogenesis, and trophoblast differentiation. Proc Natl Acad Sci U S A. 2022;119:e2200252119. https://doi.org/10.1073/pnas.2200252119.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maas JW, Groothuis PG, Dunselman GA, de Goeij AF, Struyker Boudier HA, Evers JL. Endometrial angiogenesis throughout the human menstrual cycle. Hum Reprod. 2001;16:1557–61. https://doi.org/10.1093/humrep/16.8.1557.

Article  CAS  PubMed  Google Scholar 

Rogers PA, Donoghue JF, Walter LM, Girling JE. Endometrial angiogenesis, vascular maturation, and lymphangiogenesis. Reprod Sci. 2009;16:147–51. https://doi.org/10.1177/1933719108325509.

Article  PubMed  Google Scholar 

Chen W, Lu S, Yang C, Li N, Chen X, He J, Liu X, Ding Y, Tong C, Peng C, et al. Hyperinsulinemia restrains endometrial angiogenesis during decidualization in early pregnancy. J Endocrinol. 2019;243:137–48. https://doi.org/10.1530/joe-19-0127.

Article  CAS  PubMed  Google Scholar 

Ahn J, Yoon MJ, Hong SH, Cha H, Lee D, Koo HS, Ko JE, Lee J, Oh S, Jeon NL, et al. Three-dimensional microengineered vascularised endometrium-on-a-chip. Hum Reprod. 2021;36:2720–31. https://doi.org/10.1093/humrep/deab186.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gnecco JS, Pensabene V, Li DJ, Ding T, Hui EE, Bruner-Tran KL, Osteen KG. Compartmentalized Culture of Perivascular Stroma and endothelial cells in a microfluidic model of the human endometrium. Ann Biomed Eng. 2017;45:1758–69. https://doi.org/10.1007/s10439-017-1797-5.

Article  PubMed  PubMed Central  Google Scholar 

Duran CL, Abbey CA, Bayless KJ. Establishment of a three-dimensional model to study human uterine angiogenesis. Mol Hum Reprod. 2018;24:74–93. https://doi.org/10.1093/molehr/gax064.

Article  CAS  PubMed  Google Scholar 

Binder NK, Evans J, Salamonsen LA, Gardner DK, Kaitu’u-Lino TuJ, Hannan NJ. Placental growth factor is secreted by the human endometrium and has potential important functions during embryo development and implantation. PLoS ONE. 2016;11:e0163096. https://doi.org/10.1371/journal.pone.0163096.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nejabati HR, Latifi Z, Ghasemnejad T, Fattahi A, Nouri M. Placental growth factor (PlGF) as an angiogenic/inflammatory switcher: lesson from early pregnancy losses. Gynecol Endocrinol. 2017;33:668–74. https://doi.org/10.1080/09513590.2017.1318375.

Article  CAS  PubMed  Google Scholar 

Ruggiero D, Nutile T, Nappo S, Tirozzi A, Bellenguez C, Leutenegger AL, Ciullo M. Genetics of PlGF plasma levels highlights a role of its receptors and supports the link between angiogenesis and immunity. Sci Rep. 2021;11:16821. https://doi.org/10.1038/s41598-021-96256-0.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dewerchin M, Carmeliet P. PlGF: a multitasking cytokine with disease-restricted activity. Cold Spring Harb Perspect Med. 2012;2. https://doi.org/10.1101/cshperspect.a011056.

Li X, Jin Q, Yao Q, Zhou Y, Zou Y, Li Z, Zhang S, Tu C. Placental growth factor contributes to liver inflammation, angiogenesis, fibrosis in mice by promoting hepatic macrophage recruitment and activation. Front Immunol. 2017;8:801. https://doi.org/10.3389/fimmu.2017.00801.

Article  CAS  PubMed 

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