Bokoch GM, Reilly AM, Daniels RH, King CC, Olivera A, Spiegel S, Knaus UG (1998) A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids. J Biol Chem 273:8137–8144. https://doi.org/10.1074/jbc.273.14.8137
Article CAS PubMed Google Scholar
Burchfield JS, Xie M, Hill JA (2013) Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation 128:388–400. https://doi.org/10.1161/CIRCULATIONAHA.113.001878
Article PubMed PubMed Central Google Scholar
Cuspidi C, Sala C, Negri F, Mancia G, Morganti A (2012) Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies. J Hum Hypertens 26:343–349. https://doi.org/10.1038/jhh.2011.104
Article CAS PubMed Google Scholar
Davare MA, Horne MC, Hell JW (2000) Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase. J Biol Chem 275:39710–39717. https://doi.org/10.1074/jbc.M005462200
Article CAS PubMed Google Scholar
Drazner MH (2011) The progression of hypertensive heart disease. Circulation 123:327–334. https://doi.org/10.1161/CIRCULATIONAHA.108.845792
Egom EE, Bae JS, Capel R, Richards M, Ke Y, Pharithi RB, Maher V, Kruzliak P, Lei M (2016) Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes. Mol Cell Biochem 419:83–92. https://doi.org/10.1007/s11010-016-2752-8
Article CAS PubMed Google Scholar
Eisner DA, Caldwell JL, Kistamás K, Trafford AW (2017) Calcium and excitation-contraction coupling in the heart. Circ Res 121:181–195. https://doi.org/10.1161/CIRCRESAHA.117.310230
Article CAS PubMed PubMed Central Google Scholar
Eisner DA, Caldwell JL, Trafford AW, Hutchings DC (2020) The control of diastolic calcium in the heart. Circ Res 126:395–412. https://doi.org/10.1161/CIRCRESAHA.119.315891
Article CAS PubMed PubMed Central Google Scholar
Erkens R, Kramer CM, Lückstädt W, Panknin C, Krause L, Weidenbach M, Dirzka J, Krenz T, Mergia E, Suvorava T, Kelm M, Cortese-Krott MM (2015) Left ventricular diastolic dysfunction in Nrf2 knock out mice is associated with cardiac hypertrophy, decreased expression of SERCA2a, and preserved endothelial function. Free Radic Biol Med 89:906–917. https://doi.org/10.1016/j.freeradbiomed.2015.10.409
Article CAS PubMed Google Scholar
Fang R, Zhang LL, Zhang LZ, Li W, Li M, Wen K (2017) Sphingosine 1-phosphate postconditioning protects against myocardial ischemia/reperfusion injury in rats via mitochondrial signaling and akt-gsk3β phosphorylation. Arch Med Res 48:147–155. https://doi.org/10.1016/j.arcmed.2017.03.013
Article CAS PubMed Google Scholar
Fukuhara S, Simmons S, Kawamura S, Inoue A, Orba Y, Tokudome T, Sunden Y, Arai Y, Moriwaki K, Ishida J, Uemura A, Kiyonari H, Abe T, Fukamizu A, Hirashima M, Sawa H, Aoki J, Ishii M, Mochizuki N (2012) The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. J Clin Invest 122:1416–1426. https://doi.org/10.1172/jci60746
Article CAS PubMed PubMed Central Google Scholar
Funk F, Kronenbitter A, Isic M, Flocke V, Gorressen S, Semmler D, Brinkmann M, Beck K, Steinhoff O, Srivastava T, Barbosa DM, Voigt K, Wang L, Bottermann K, Kotter S, Grandoch M, Flogel U, Kruger M, Schmitt JP (2022) Diabetes disturbs functional adaptation of the remote myocardium after ischemia/reperfusion. J Mol Cell Cardiol 173:47–60. https://doi.org/10.1016/j.yjmcc.2022.09.002
Article CAS PubMed Google Scholar
Gorski PA, Ceholski DK, Hajjar RJ (2015) Altered myocardial calcium cycling and energetics in heart failure—a rational approach for disease treatment. Cell Metab 21:183–194. https://doi.org/10.1016/j.cmet.2015.01.005
Article CAS PubMed PubMed Central Google Scholar
Guenther GG, Peralta ER, Rosales KR, Wong SY, Siskind LJ, Edinger AL (2008) Ceramide starves cells to death by downregulating nutrient transporter proteins. Proc Natl Acad Sci USA 105:17402–17407. https://doi.org/10.1073/pnas.0802781105
Article PubMed PubMed Central Google Scholar
Habrukowich C, Han DK, Le A, Rezaul K, Pan W, Ghosh M, Li Z, Dodge-Kafka K, Jiang X, Bittman R, Hla T (2010) Sphingosine interaction with acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) regulates PP2A activity and cyclooxygenase (COX)-2 expression in human endothelial cells. J Biol Chem 285:26825–26831. https://doi.org/10.1074/jbc.M110.147058
Article CAS PubMed PubMed Central Google Scholar
Hall DD, Feekes JA, Arachchige Don AS, Shi M, Hamid J, Chen L, Strack S, Zamponi GW, Horne MC, Hell JW (2006) Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser 1928, its main PKA site, is critical for Ser1928 dephosphorylation. Biochemistry 45:3448–3459. https://doi.org/10.1021/bi051593z
Article CAS PubMed Google Scholar
Heusch G, Libby P, Gersh B, Yellon D, Böhm M, Lopaschuk G, Opie L (2014) Cardiovascular remodelling in coronary artery disease and heart failure. Lancet 383:1933–1943. https://doi.org/10.1016/s0140-6736(14)60107-0
Article PubMed PubMed Central Google Scholar
Hill JA, Olson EN (2008) Cardiac plasticity. N Engl J Med 358:1370–1380. https://doi.org/10.1056/NEJMra072139
Article CAS PubMed Google Scholar
Jin Z-Q, Zhang J, Huang Y, Hoover HE, Vessey DA, Karliner JS (2007) A sphingosine kinase 1 mutation sensitizes the myocardium to ischemia/reperfusion injury. Cardiovasc Res 76:41–50. https://doi.org/10.1016/j.cardiores.2007.05.029
Article CAS PubMed Google Scholar
Józefczuk E, Nosalski R, Saju B, Crespo E, Szczepaniak P, Guzik TJ, Siedlinski M (2020) Cardiovascular effects of pharmacological targeting of sphingosine kinase 1. Hypertension 75:383–392. https://doi.org/10.1161/HYPERTENSIONAHA.119.13450
Article CAS PubMed Google Scholar
Jujic A, Matthes F, Vanherle L, Petzka H, Orho-Melander M, Nilsson PM, Magnusson M, Meissner A (2021) Plasma S1P (sphingosine-1-phosphate) links to hypertension and biomarkers of inflammation and cardiovascular disease: findings from a translational investigation. Hypertension 78:195–209. https://doi.org/10.1161/HYPERTENSIONAHA.120.17379
Article CAS PubMed Google Scholar
Juraszek B, Nalecz KA (2016) Protein phosphatase PP2A—a novel interacting partner of carnitine transporter OCTN2 (SLC22A5) in rat astrocytes. J Neurochem 139:537–551. https://doi.org/10.1111/jnc.13777
Article CAS PubMed Google Scholar
Ke Y, Lei M, Solaro RJ (2008) Regulation of cardiac excitation and contraction by p21 activated kinase-1. Prog Biophys Mol Biol 98:238–250. https://doi.org/10.1016/j.pbiomolbio.2009.01.007
Article CAS PubMed Google Scholar
Keul P, Sattler K, Levkau B (2007) HDL and its sphingosine-1-phosphate content in cardioprotection. Heart Fail Rev 12:301–306. https://doi.org/10.1007/s10741-007-9038-x
Article CAS PubMed Google Scholar
Keul P, van Borren MM, Ghanem A, Müller FU, Baartscheer A, Verkerk AO, Stümpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot JH, Alewijnse AE, Hermann S, Spijkers LJ, Hiller KH, Herr D, Heusch G, Schäfers M, Peters SL, Chun J, Levkau B (2016) Sphingosine-1-phosphate receptor 1 regulates cardiac function by modulating Ca2+ sensitivity and Na+/H+ exchange and mediates protection by ischemic preconditioning. J Am Heart Assoc 5:e003393. https://doi.org/10.1161/jaha.116.003393
留言 (0)