Oka T, Akazawa H, Naito AT, Komuro I. Angiogenesis and cardiac hypertrophy: maintenance of cardiac function and causative roles in heart failure. Circ Res. 2014;114(3):565–71.

Article  CAS  PubMed  Google Scholar 

Bacmeister L, Schwarzl M, Warnke S, Stoffers B, Blankenberg S, Westermann D, Lindner D. Inflammation and fibrosis in murine models of heart failure. Basic Res Cardiol. 2019;114:1–35.

Article  CAS  Google Scholar 

Members WC, Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, Jessup M, Konstam MA, Mancini DM. ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005;112(12):e154–235.

Google Scholar 

Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. lancet. 2012;380(9859):2163–96.

Article  PubMed  PubMed Central  Google Scholar 

Heidenreich PA, Albert NM, Allen LA, Bluemke DA, Butler J, Fonarow GC, Ikonomidis JS, Khavjou O, Konstam MA, Maddox TM. Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association. Circ Heart Fail. 2013;6(3):606–19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maggioni AP, Dahlström U, Filippatos G, Chioncel O, Leiro MC, Drozdz J, Fruhwald F, Gullestad L, Logeart D, Fabbri G. EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot). Eur J Heart Fail. 2013;15(7):808–17.

Article  PubMed  Google Scholar 

Wang H, Chai K, Du MH, Wang SF, Cai J-P, Li Y, Zeng P, Zhu W, Zhan S, Yang J. Prevalence and incidence of heart failure among urban patients in China: a national population-based analysis. Circ Heart Fail. 2021;14(10):e008406.

Article  PubMed  Google Scholar 

McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2021;42(36):3599–726.

Article  CAS  PubMed  Google Scholar 

Wang Y, Wang QY, Li C, Lu L, Zhang Q, Zhu R, Wang W. A review of Chinese herbal medicine for the treatment of chronic heart failure. Curr Pharm Des. 2017;23(34):5115–24.

CAS  PubMed  PubMed Central  Google Scholar 

Arunkumar A, Dhyani A, Joshi G. Santalum album. The IUCN red list of threatened species. 2019: 2019–1.

Shi SH, Cai YP, Cai XJ, Zheng X-Y, Cao D-S, Ye F-Q, Xiang Z. A network pharmacology approach to understanding the mechanisms of action of traditional medicine: Bushenhuoxue formula for treatment of chronic kidney disease. PLoS ONE. 2014;9(3):e89123.

Article  PubMed  PubMed Central  Google Scholar 

Saneja A, Kaushik P, Kaushik D, Kumar S, Kumar D. Antioxidant, analgesic and anti-inflammatory activities of Santalum album Linn. Planta Med. 2009;75(04):102.

Article  Google Scholar 

Suganya K, Liu QF, Koo BS. Santalum album extract exhibits neuroprotective effect against the TLR3-mediated neuroinflammatory response in human SH-SY5Y neuroblastoma cells. Phytother Res. 2021;35(4):1991–2004.

Article  CAS  PubMed  Google Scholar 

Santha S, Dwivedi C. Anticancer effects of sandalwood (Santalum album). Anticancer Res. 2015;35(6):3137–45.

CAS  PubMed  Google Scholar 

Liu JL, Mu JX, Zheng CL, Chen X, Guo Z, Huang C, Fu Y, Tian G, Shang H, Wang Y. Systems-pharmacology dissection of traditional Chinese medicine compound saffron formula reveals multi-scale treatment strategy for cardiovascular diseases. Sci Rep. 2016;6(1):19809.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang ZT, Sun HX, Su SS, Nan X, Li K, Jin X, Jin G, Li Z, Lu D. Tsantan Sumtang restored right ventricular function in chronic hypoxia-induced pulmonary hypertension rats. Front Pharmacol. 2021;11:607384.

Article  PubMed  PubMed Central  Google Scholar 

Nazeer Ahmed NA, Khan M, Abdul Manan M, Norhafizah Mohtarrudin NM, Maryam Ranjbar MR, Amjad M, Bee Nagaraju BN, Mohammed Faraz MF, Faiyaz Pathan FP, Anand Chincholi AC. Anti-ulcer activity of Sandalwood (Santalum album L.) stem hydro-alcoholic extract in three gastric-ulceration models of Wistar rats. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas. 2013;12(1):81-91.

Misra BB, Dey S. Evaluation of in vivo anti-hyperglycemic and antioxidant potentials of α-santalol and sandalwood oil. Phytomedicine. 2013;20(5):409–16.

Article  CAS  PubMed  Google Scholar 

Mohankumar A, Kalaiselvi D, Levenson C, Shanmugam G, Thiruppathi G, Nivitha S, Sundararaj P. Antioxidant and stress modulatory efficacy of essential oil extracted from plantation-grown Santalum album L. Ind Crops Prod. 2019;140:111623.

Article  CAS  Google Scholar 

Shahzad S, Mateen S, Mariyath PM, Naeem SS, Akhtar K, Rizvi W, Moin S. Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. Biomed Pharmacother. 2018;108:625–33.

Article  CAS  PubMed  Google Scholar 

Ahmed K, Jahan N, Kausar SH, Irshad S. Cardioprotective effect of Sandal wood (Santalum album L.): an experimental trail. Int J Pharm Sci Res. 2022;13:3304–17.

CAS  Google Scholar 

Sharifi-Rad J, Quispe C, Turgumbayeva A, Mertdinç Z, Tütüncü S, Aydar EF, Özçelik B, Anna S-W, Mariola S, Koziróg A. Santalum Genus: phytochemical constituents, biological activities and health promoting-effects. Zeitschrift für Naturforschung C. 2023;78(1–2):9–25.

Article  CAS  Google Scholar 

Li YP, Xu C, Wang HQ, Liu XB, Jiang L, Liang S, Wu Z, Wang Z, Zhou J, Xiao W. Systems pharmacology reveals the multi-level synergetic mechanism of action of Ginkgo biloba L. leaves for cardiomyopathy treatment. J Ethnopharmacol. 2021;264:113279.

Article  CAS  PubMed  Google Scholar 

Yang YF, Li Y, Wang JH, Sun K, Tao W, Wang Z, Xiao W, Pan Y, Zhang S, Wang Y. Systematic investigation of Ginkgo biloba leaves for treating cardio-cerebrovascular diseases in an animal model. ACS Chem Biol. 2017;12(5):1363–72.

Article  CAS  PubMed  Google Scholar 

Ru JL, Li P, Wang JN, Zhou W, Li B, Huang C, Li P, Guo Z, Tao W, Yang Y. TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. J Cheminform. 2014;6:1–6.

Article  Google Scholar 

Li P, Huang C, Fu YX, Wang JN, Wu Z, Ru J, Zheng C, Guo Z, Chen X, Zhou W. Large-scale exploration and analysis of drug combinations. Bioinformatics. 2015;31(12):2007–16.

Article  CAS  PubMed  Google Scholar 

Liu J, Zhu J, Xue J, Qin Z, Shen F, Liu J, Chen X, Li X, Wu Z, Xiao W. In silico-based screen synergistic drug combinations from herb medicines: a case using Cistanche tubulosa. Sci Rep. 2017;7(1):16364.

Article  PubMed  PubMed Central  Google Scholar 

Zhang W, Huai Y, Miao Z, Qian A, Wang Y. Systems pharmacology for investigation of the mechanisms of action of traditional Chinese medicine in drug discovery. Front Pharmacol. 2019;10:743.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13(11):2498–504.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ol K, Kanbak G, Ilhan A, Kartkaya K, Inal M. Morinda citrifolia (noni) and low dose aspirin prevent apoptotic cell death and oxidative stress on isoproterenol induced myocardial infarction in rats. Erciyes Med J. 2017;39(4):165–70.

Article  CAS  Google Scholar 

Khan MS, Singh M, Khan MA, Ahmad S. Protective effect of Santalum album on doxorubicin induced cardiotoxicity in rats. World J Pharm Res. 2014;3(2):2760–71.

Google Scholar 

Zhang X, Du QM, Yang Y, Wang J, Dou S, Liu C, Duan J. The protective effect of Luteolin on myocardial ischemia/reperfusion (I/R) injury through TLR4/NF-κB/NLRP3 inflammasome pathway. Biomed Pharmacother. 2017;91:1042–52.

Article  CAS  PubMed