Kotas ME, Medzhitov R. Homeostasis, inflammation, and disease susceptibility. Cell. 2015;160:816–27.
Article CAS PubMed PubMed Central Google Scholar
Bettcher BM, Tansey MG, Dorothée G, Heneka MT. Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus. Nat Rev Neurol. 2021;17:689–701.
Article PubMed PubMed Central Google Scholar
Meltzer A, Van de Water J. The role of the immune system in autism spectrum disorder. Neuropsychopharmacology. 2017;42:284–98.
Article CAS PubMed Google Scholar
Donath MY, Dinarello CA, Mandrup-Poulsen T. Targeting innate immune mediators in type 1 and type 2 diabetes. Nat Rev Immunol. 2019;19:734–46.
Article CAS PubMed Google Scholar
Hiam-Galvez KJ, Allen BM, Spitzer MH. Systemic immunity in cancer. Nat Rev Cancer. 2021;21:345–59.
Article CAS PubMed PubMed Central Google Scholar
Quah HS, Cao EY, Suteja L, Li CH, Leong HS, Chong FT, et al. Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis. Nat Commun. 2023;14:1680.
Article CAS PubMed PubMed Central Google Scholar
Kwok AJ, Allcock A, Ferreira RC, Cano-Gamez E, Smee M, Burnham KL, et al. Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis. Nat Immunol. 2023;24:767–79.
Article CAS PubMed Google Scholar
Lutgens E, Atzler D, Döring Y, Duchene J, Steffens S, Weber C. Immunotherapy for cardiovascular disease. Eur Heart J. 2019;40:3937–46.
Article CAS PubMed Google Scholar
Esfahani K, Roudaia L, Buhlaiga N, Del Rincon SV, Papneja N, Miller WH Jr. A review of cancer immunotherapy: from the past, to the present, to the future. Curr Oncol. 2020;27:S87-97.
Article CAS PubMed PubMed Central Google Scholar
Abdelfattah N, Kumar P, Wang C, Leu J-S, Flynn WF, Gao R, et al. Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target. Nat Commun. 2022;13:767.
Article CAS PubMed PubMed Central Google Scholar
Kaufmann SHE. Immunology’s coming of age. Front Immunol. 2019;10:684.
Article CAS PubMed PubMed Central Google Scholar
Picot J, Guerin CL, Le Van KC, Boulanger CM. Flow cytometry: retrospective, fundamentals and recent instrumentation. Cytotechnology. 2012;64:109–30.
Article PubMed PubMed Central Google Scholar
Bandura DR, Baranov VI, Ornatsky OI, Antonov A, Kinach R, Lou X, et al. Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. Anal Chem. 2009;81:6813–22.
Article CAS PubMed Google Scholar
Pittet MJ, Michielin O, Migliorini D. Clinical relevance of tumour-associated macrophages. Nat Rev Clin Oncol. 2022;19:402–21.
Gomes T, Teichmann SA, Talavera-López C. Immunology driven by large-scale single-cell sequencing. Trends Immunol. 2019;40:1011–21.
Article CAS PubMed Google Scholar
Ginhoux F, Yalin A, Dutertre CA, Amit I. Single-cell immunology: Past, present, and future. Immunity. 2022;55:393–404.
Article CAS PubMed Google Scholar
Papalexi E, Satija R. Single-cell RNA sequencing to explore immune cell heterogeneity. Nat Rev Immunol. 2018;18:35–45.
Article CAS PubMed Google Scholar
Efremova M, Vento-Tormo R, Park J-E, Teichmann SA, James KR. Immunology in the era of single-cell technologies. Annu Rev Immunol. 2020;38:727–57.
Article CAS PubMed Google Scholar
Rood JE, Maartens A, Hupalowska A, Teichmann SA, Regev A. Impact of the human cell Atlas on medicine. Nat Med. 2022;28:2486–96.
Article CAS PubMed Google Scholar
Haque A, Engel J, Teichmann SA, Lönnberg T. A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications. Genome Med. 2017;9:75.
Article PubMed PubMed Central Google Scholar
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, et al. The human cell atlas. Elife. 2017;6:e27041. https://doi.org/10.7554/eLife.27041.
Article PubMed PubMed Central Google Scholar
Domínguez Conde C, Xu C, Jarvis LB, Rainbow DB, Wells SB, Gomes T, et al. Cross-tissue immune cell analysis reveals tissue-specific features in humans. Science. 2022;376:eabl5197.
Article PubMed PubMed Central Google Scholar
Eraslan G, Drokhlyansky E, Anand S, Fiskin E, Subramanian A, Slyper M, et al. Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function. Science. 2022;376:eabl4290.
Article CAS PubMed PubMed Central Google Scholar
Suo C, Dann E, Goh I, Jardine L, Kleshchevnikov V, Park J-E, et al. Mapping the developing human immune system across organs. Science. 2022;376:eabo0510.
Article CAS PubMed Google Scholar
Sikkema L, Ramírez-Suástegui C, Strobl DC, Gillett TE, Zappia L, Madissoon E, et al. An integrated cell atlas of the lung in health and disease. Nat Med. 2023;29:1563–77.
Article CAS PubMed PubMed Central Google Scholar
Delorey TM, Ziegler CGK, Heimberg G, Normand R, Yang Y, Segerstolpe Å, et al. COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. Nature. 2021;595:107–13.
Article CAS PubMed PubMed Central Google Scholar
Luo G, Gao Q, Zhang S, Yan B. Probing infectious disease by single-cell RNA sequencing: progresses and perspectives. Comput Struct Biotechnol J. 2020;18:2962–71.
Article CAS PubMed PubMed Central Google Scholar
Yang W, Liu L-B, Liu F-L, Wu Y-H, Zhen Z-D, Fan D-Y, et al. Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation. Nat Commun. 2023;14:2476.
Article CAS PubMed PubMed Central Google Scholar
Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, et al. A molecular single-cell lung atlas of lethal COVID-19. Nature. 2021;595:114–9.
Article CAS PubMed PubMed Central Google Scholar
Sungnak W, Huang N, Bécavin C, Be
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