Azizi G, Boghozian R, Mirshafiey A (2014) The potential role of angiogenic factors in rheumatoid arthritis. Int J Rheum Dis 17(4):369–383. https://doi.org/10.1111/1756-185x.12280

Article  CAS  PubMed  Google Scholar 

Bastiaansen-Jenniskens YM, Wei W, Feijt C, Waarsing JH, Verhaar JA, Zuurmond AM, Hanemaaijer R, Stoop R, van Osch GJ (2013) Stimulation of fibrotic processes by the infrapatellar fat pad in cultured synoviocytes from patients with osteoarthritis: a possible role for prostaglandin f2α. Arthritis Rheum 65(8):2070–2080. https://doi.org/10.1002/art.37996

Article  CAS  PubMed  Google Scholar 

Bertuglia A, Lacourt M, Girard C, Beauchamp G, Richard H, Laverty S (2016) Osteoclasts are recruited to the subchondral bone in naturally occurring post-traumatic equine carpal osteoarthritis and may contribute to cartilage degradation. Osteoarthr Cartil 24(3):555–566. https://doi.org/10.1016/j.joca.2015.10.008

Article  CAS  Google Scholar 

Bijlsma JW, Berenbaum F, Lafeber FP (2011) Osteoarthritis: an update with relevance for clinical practice. Lancet 377(9783):2115–2126. https://doi.org/10.1016/S0140-6736(11)60243-2

Article  PubMed  Google Scholar 

Boppart MD, Burkin DJ, Kaufman SJ (2011) Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy. Biochim Biophys Acta 1812(4):439–446. https://doi.org/10.1016/j.bbadis.2011.01.002

Article  CAS  PubMed  PubMed Central  Google Scholar 

Botter SM, van Osch GJ, Waarsing JH, van der Linden JC, Verhaar JA, Pols HA, van Leeuwen JP, Weinans H (2008) Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis. Osteoarthr Cartil 16(4):506–514. https://doi.org/10.1016/j.joca.2007.08.005

Article  CAS  Google Scholar 

Bougeret C, Mansur IG, Dastot H, Schmid M, Mahouy G, Bensussan A, Boumsell L (1992) Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation. J Immunol 148(2):318–323

Article  CAS  PubMed  Google Scholar 

Burrage PS, Mix KS, Brinckerhoff CE (2006) Matrix metalloproteinases: role in arthritis. Front Biosci 11:529–543. https://doi.org/10.2741/1817

Article  CAS  PubMed  Google Scholar 

Carr AJ, Robertsson O, Graves S, Price AJ, Arden NK, Judge A, Beard DJ (2012) Knee replacement. Lancet 379(9823):1331–1340. https://doi.org/10.1016/S0140-6736(11)60752-6

Article  PubMed  Google Scholar 

Catalano A (2010) The neuroimmune semaphorin-3A reduces inflammation and progression of experimental autoimmune arthritis. J Immunol 185(10):6373–6383. https://doi.org/10.4049/jimmunol.0903527

Article  CAS  PubMed  Google Scholar 

Charlier E, Deroyer C, Ciregia F, Malaise O, Neuville S, Plener Z, Malaise M, de Seny D (2019) Chondrocyte dedifferentiation and osteoarthritis (OA). Biochem Pharmacol 165:49–65. https://doi.org/10.1016/j.bcp.2019.02.036

Article  CAS  PubMed  Google Scholar 

Chen H, Wu G, Sun Q, Dong Y, Zhao H (2016) Hyperbaric oxygen protects mandibular condylar chondrocytes from interleukin-1β-induced apoptosis via the PI3K/AKT signaling pathway. Am J Transl Res 8(11):5108–5117

CAS  PubMed  PubMed Central  Google Scholar 

Chen Y, Zhang L, Liu WX, Wang K (2018) VEGF and SEMA4D have synergistic effects on the promotion of angiogenesis in epithelial ovarian cancer. Cell Mol Biol Lett 23:2. https://doi.org/10.1186/s11658-017-0058-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen WG, Sun J, Shen WW, Yang SZ, Zhang Y, Hu X, Qiu H, Xu SC, Chu TW (2019) Sema4D expression and secretion are increased by HIF-1α and inhibit osteogenesis in bone metastases of lung cancer. Clin Exp Metastasis 36(1):39–56. https://doi.org/10.1007/s10585-018-9951-5

Article  CAS  PubMed  Google Scholar 

Cheng Q, Chen M, Liu M, Chen X, Zhu L, Xu J, Xue J, Wu H, Du Y (2022) Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis. Cell Death Dis 13(7):608. https://doi.org/10.1038/s41419-022-05065-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chung L, Shimokawa K, Dinakarpandian D, Grams F, Fields GB, Nagase H (2000) Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity. J Biol Chem 275(38):29610–29617. https://doi.org/10.1074/jbc.M004039200

Article  CAS  PubMed  Google Scholar 

Cui Z, Crane J, Xie H, Jin X, Zhen G, Li C, Xie L, Wang L, Bian Q, Qiu T, Wan M, Xie M, Ding S, Yu B, Cao X (2016) Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone. Ann Rheum Dis 75(9):1714–1721. https://doi.org/10.1136/annrheumdis-2015-207923

Article  CAS  PubMed  Google Scholar 

Dall’Ara E, Ohman C, Baleani M, Viceconti M (2011) Reduced tissue hardness of trabecular bone is associated with severe osteoarthritis. J Biomech 44(8):1593–1598. https://doi.org/10.1016/j.jbiomech.2010.12.022

Article  PubMed  Google Scholar 

de Wit J, Verhaagen J (2003) Role of semaphorins in the adult nervous system. Prog Neurobiol 71(2–3):249–267. https://doi.org/10.1016/j.pneurobio.2003.06.001

Article  CAS  PubMed  Google Scholar 

Elhabazi A, Marie-Cardine A, Chabbert-de Ponnat I, Bensussan A, Boumsell L (2003) Structure and function of the immune semaphorin CD100/SEMA4D. Crit Rev Immunol 23(1–2):65–81. https://doi.org/10.1615/critrevimmunol.v23.i12.40

Article  CAS  PubMed  Google Scholar 

Findlay DM, Atkins GJ (2014) Osteoblast-chondrocyte interactions in osteoarthritis. Curr Osteoporos Rep 12(1):127–134. https://doi.org/10.1007/s11914-014-0192-5

Article  PubMed  PubMed Central  Google Scholar 

Fransès RE, McWilliams DF, Mapp PI, Walsh DA (2010) Osteochondral angiogenesis and increased protease inhibitor expression in OA. Osteoarthr Cartil 18(4):563–571. https://doi.org/10.1016/j.joca.2009.11.015

Article  Google Scholar 

Fukuda T, Takeda S, Xu R, Ochi H, Sunamura S, Sato T, Shibata S, Yoshida Y, Gu Z, Kimura A, Ma C, Xu C, Bando W, Fujita K, Shinomiya K, Hirai T, Asou Y, Enomoto M, Okano H, Okawa A, Itoh H (2013) Sema3A regulates bone-mass accrual through sensory innervations. Nature 497(7450):490–493. https://doi.org/10.1038/nature12115

Article  CAS  PubMed  Google Scholar 

Gao H, Ma XX, Guo Q, Xie LF, Zhong YC, Zhang XW (2018) Expression of circulating Semaphorin3A and its association with inflammation and bone destruction in rheumatoid arthritis. Clin Rheumatol 37(8):2073–2080. https://doi.org/10.1007/s10067-018-4070-x

Article  PubMed  Google Scholar 

Garcia S (2019) Role of semaphorins in immunopathologies and rheumatic diseases. Int J Mol Sci. https://doi.org/10.3390/ijms20020374

Article  PubMed  PubMed Central  Google Scholar 

Gaur P, Bielenberg DR, Samuel S, Bose D, Zhou Y, Gray MJ, Dallas NA, Fan F, Xia L, Lu J, Ellis LM (2009) Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis. Clin Cancer Res 15(22):6763–6770. https://doi.org/10.1158/1078-0432.Ccr-09-1810

Article  CAS  PubMed  Google Scholar 

Geretti E, Shimizu A, Klagsbrun M (2008) Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis. Angiogenesis 11(1):31–39. https://doi.org/10.1007/s10456-008-9097-1

Article  CAS  PubMed  Google Scholar 

Glyn-Jones S, Palmer AJ, Agricola R, Price AJ, Vincent TL, Weinans H, Carr AJ (2015) Osteoarthritis. Lancet 386(9991):376–387. https://doi.org/10.1016/s0140-6736(14)60802-3

Article  CAS  PubMed  Google Scholar 

Gomoll AH, Madry H, Knutsen G, van Dijk N, Seil R, Brittberg M, Kon E (2010) The subchondral bone in articular cartilage repair: current problems in the surgical management. Knee Surg Sports Traumatol Arthrosc 18(4):434–447.