Advances in Pharmacology and Pharmacy Vol. 12(3), pp. 164 - 176
DOI: 10.13189/app.2024.120302
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Vimal Priya Subramanian 1, Karthika Krishnamoorthy 1,*, Paulsamy Subramaniam 2
1 Department of Botany, Kongunadu Arts and Science College (Autonomous), India
2 Kongunadu Arts and Science College (Autonomous), India

ABSTRACT

The species Vincetoxicum subramanii is a traditional medicinal plant of the Apocynaceae family and endemic to Southern Western Ghats, India. It is used to treat ailments such as fever, colds, constipation, diarrhea, ulcers, external tumors, cuts, and relief pain. The present investigation aims to study the phytochemicals, medicinal importance and antioxidant activity of the stem part. The results of the study revealed the presence of total alkaloid content, 70.95±0.60 mg/g in the dried plant material. The ethanol extract of stem has the highest amount of polyphenols - 166.58 mg GAE/g extract, tannins - 99.231 mg GAE/g extract and ascorbic acid - 68,240.7 mg AAE/g extract. However, the chloroform extract was with high amount of flavonoids - 294.04 mg RE/g extract. The highest quantity of saponin - 88.92±1.04 mg DE/g, was noted in hexane extract. The antioxidant assays obtained were highest in stem ethanol extract of the species. The results of this study showed that ethanol extracts from stem of V. subramanii exhibited significant antioxidant activity. Consequently, the results may form the basis for the development of effective antioxidants using V. subramanii, and this would be the first reported scientific rationale to validate its traditional therapeutic use.

KEYWORDS
Vincetoxicum subramanii, in vitro Antioxidant, DPPH, ABTS, Metal Chelating, Total Phenol

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Vimal Priya Subramanian , Karthika Krishnamoorthy , Paulsamy Subramaniam , "Elucidation of Phytochemicals in Stem Part and Evaluation of their Antioxidant Properties of Vincetoxicum subramanii (A. N. Henry) Meve & Liede (Apocynaceae)," Advances in Pharmacology and Pharmacy, Vol. 12, No. 3, pp. 164 - 176, 2024. DOI: 10.13189/app.2024.120302.

(b). APA Format:
Vimal Priya Subramanian , Karthika Krishnamoorthy , Paulsamy Subramaniam (2024). Elucidation of Phytochemicals in Stem Part and Evaluation of their Antioxidant Properties of Vincetoxicum subramanii (A. N. Henry) Meve & Liede (Apocynaceae). Advances in Pharmacology and Pharmacy, 12(3), 164 - 176. DOI: 10.13189/app.2024.120302.