Drugs in Human Milk Part 1: Practical and Analytical Considerations in Measuring Drugs and Metabolites in Human Milk

Ayad M, Costantine MM. Epidemiology of medications use in pregnancy. Semin Perinatol. 2015;39(7):508–11.

Article  PubMed  PubMed Central  Google Scholar 

Saha MR, Ryan K, Amir LH. Postpartum women’s use of medicines and breastfeeding practices: a systematic review. Int Breastfeed J. 2015;10:28.

Article  PubMed  PubMed Central  Google Scholar 

Ito S, Lee A. Drug excretion into breast milk–overview. Adv Drug Deliv Rev. 2003;55(5):617–27.

Article  CAS  PubMed  Google Scholar 

Friguls B, Joya X, Garcia-Algar O, et al. A comprehensive review of assay methods to determine drugs in breast milk and the safety of breastfeeding when taking drugs. Anal Bioanal Chem. 2010;397(3):1157–79.

Article  CAS  PubMed  Google Scholar 

Wang J, Johnson T, Sahin L, et al. Evaluation of the safety of drugs and biological products used during lactation: workshop summary. Clin Pharmacol Ther. 2017;101(6):736–44.

Article  CAS  PubMed  Google Scholar 

Shapiro RL, Holland DT, Capparelli E, et al. Antiretroviral concentrations in breast-feeding infants of women in Botswana receiving antiretroviral treatment. J Infect Dis. 2005;192(5):720–7.

Article  CAS  PubMed  Google Scholar 

Ballard O, Morrow AL. Human milk composition: nutrients and bioactive factors. Pediatr Clin N Am. 2013;60(1):49–74.

Article  Google Scholar 

van Sadelhoff JHJ, Mastorakou D, Weenen H, et al. Short communication: differences in levels of free amino acids and total protein in human foremilk and hindmilk. Nutrients. 2018;10(12):1828.

Article  PubMed  PubMed Central  Google Scholar 

Lopes BR, Barreiro JC, Cass QB. Bioanalytical challenge: a review of environmental and pharmaceuticals contaminants in human milk. J Pharm Biomed. 2016;25(130):318–25.

Article  Google Scholar 

Hassiotou F, Geddes D. Anatomy of the human mammary gland: current status of knowledge. Clin Anat. 2013;26(1):29–48.

Article  PubMed  Google Scholar 

McManaman JL, Neville MC. Mammary physiology and milk secretion. Adv Drug Deliv Rev. 2003;55(5):629–41.

Article  CAS  PubMed  Google Scholar 

Pang WW, Hartmann PE. Initiation of human lactation: secretory differentiation and secretory activation. J Mammary Gland Biol Neoplasia. 2007;12(4):211–21.

Article  PubMed  Google Scholar 

Quezada A, Vafai K. Modeling and analysis of transport in the mammary glands. Phys Biol. 2014;11(4): 045004.

Article  PubMed  Google Scholar 

Macias H, Hinck L. Mammary gland development. Wiley Interdiscip Rev Dev Biol. 2012;1(4):533–57.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fleishaker JC. Models and methods for predicting drug transfer into human milk. Adv Drug Deliv Rev. 2003;55(5):643–52.

Article  CAS  PubMed  Google Scholar 

Godhia ML, Patel N. Colostrum-its composition, benefits as a nutraceutical - a review. Curr Res Nutr Food Sci. 2013;1(1):37–47.

Article  Google Scholar 

Kim SY, Yi DY. Components of human breast milk: from macronutrient to microbiome and microRNA. Clin Exp Pediatr. 2020;63(8):301–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andreas NJ, Kampmann B, Mehring L-D. Human breast milk: a review on its composition and bioactivity. Early Hum Dev. 2015;91(11):629–35.

Article  CAS  PubMed  Google Scholar 

Stowe ZN, Hostetter AL, Owens MJ, et al. The pharmacokinetics of sertraline excretion into human breast milk: determinants of infant serum concentrations. J Clin Psychiatry. 2003;64(1):73–80.

Article  CAS  PubMed  Google Scholar 

García-Lino AM, Álvarez-Fernández I, Blanco-Paniagua E, et al. Transporters in the mammary gland-contribution to presence of nutrients and drugs into milk. Nutrients. 2019;11(10):2372.

Article  PubMed  PubMed Central  Google Scholar 

Atkinson HC, Begg EJ. Prediction of drug distribution into human milk from physicochemical characteristics. Clin Pharmacokinet. 1990;18(2):151–67.

Article  CAS  PubMed  Google Scholar 

JTW. Drugs in Breast Milk, 2nd ed. In: ADIS; 1981.

Ito S, Alcorn J. Xenobiotic transporter expression and function in the human mammary gland. Adv Drug Deliv Rev. 2003;55(5):653–65.

Article  CAS  PubMed  Google Scholar 

Hodel EM, Marzolini C, Waitt C, et al. Pharmacokinetics, placental and breast milk transfer of antiretroviral drugs in pregnant and lactating women living with HIV. Curr Pharm Des. 2019;25(5):556–76.

Article  CAS  PubMed  Google Scholar 

Gao B, Vavricka SR, Meier PJ, et al. Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS. Pflugers Arch. 2015;467(7):1481–93.

Article  CAS  PubMed  Google Scholar 

Seaton S, Reeves M, McLean S. Oxycodone as a component of multimodal analgesia for lactating mothers after Caesarean section: relationships between maternal plasma, breast milk and neonatal plasma levels. Aus NZJ Obstet Gynaecol. 2007;47(3):181–5.

Article  Google Scholar 

Malfara BN, Benzi JRL, de Oliveira Filgueira GC, et al. ABCG2 c.421C>A polymorphism alters nifedipine transport to breast milk in hypertensive breastfeeding women. Reprod Toxicol. 2019;85:1–5.

Article  CAS  PubMed  Google Scholar 

Jonker JW, Merino G, Musters S, et al. The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nat Med. 2005;11(2):127–9.

Article  CAS  PubMed  Google Scholar 

Banta-Wright SA. Minimizing infant exposure to and risks from medications while breastfeeding. J Perinat Neonatal Nurs. 1997;11(2):71–84 (quiz 85-6).

Article  CAS  PubMed  Google Scholar 

Breitzka RL, Sandritter TL, Hatzopoulos FK. Principles of drug transfer into breast milk and drug disposition in the nursing infant. J Hum Lact. 1997;13(2):155–8.

Article  CAS  PubMed  Google Scholar 

Lipinski CA, Lombardo F, Dominy BW, et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev. 2001;46(1–3):3–26.

Article  CAS  PubMed  Google Scholar 

Development. NIoCHaH. Drugs and Lactation Database (LactMed(R)). 2021. https://www.ncbi.nlm.nih.gov/books/NBK501922/. Accessed 1 Dec 2023.

Rivera-calimlim L. Drugs in breast milk. Drug Ther (NY). 1977;7(12):59–63.

CAS  PubMed  Google Scholar 

Özdemir Z, Traş B. Behaviours of drugs in the milk - a review. Vet Sci Prac. 2018;13(3):364–72.

Google Scholar 

Sisodia CS, Stowe CM. The mechanism of drug secretion into bovine milk. Ann NY Acad Sci. 1964;24(111):650–61.

Article  Google Scholar 

Wilson JT, Brown RD, Cherek DR, et al. Drug excretion in human breast milk: principles, pharmacokinetics and projected consequences. Clin Pharmacokinet. 1980;5(1):1–66.

Article  CAS  PubMed  Google Scholar 

Syversen GB, Ratkje SK. Drug distribution within human milk phases. J Pharm Sci. 1985;74(10):1071–4.

Article  CAS  PubMed  Google Scholar 

Smith JA, Morgan JR, Rachlis AR, et al. Clindamycin in human breast milk. Can Med Assoc J. 1975;112(7):806.

CAS  PubMed  PubMed Central  Google Scholar 

Cahill JB Jr, Bailey EM, Chien S, et al. Levofloxacin secretion in breast milk: a case report. Pharmacotherapy. 2005;25(1):116–8.

Article  PubMed  Google Scholar 

Khurana R, Bin Jardan YA, Wilkie J, et al. Breast milk concentrations of amiodarone, desethylamiodarone, and bisoprolol following short-term drug exposure: two case reports. J Clin Pharmacol. 2014;54(7):828–31.

Article  CAS  PubMed  Google Scholar 

Lutz UC, Wiatr G, Orlikowsky T, et al. Olanzapine treatment during breast feeding: a case report. Ther Drug Monit. 2008;30(3):399–401.

Article  PubMed  Google Scholar 

Rowe HE, Felkins K, Cooper SD, et al. Transfer of linezolid into breast milk. J Hum Lact. 2014;30(4):410–2.

Article  PubMed 

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