Aran D et al (2019) Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol 20(2):163–172

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barr TL et al (2010) Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profiling. Neurology 75(11):1009–1014

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barthels D, Das H (2020) Current advances in ischemic stroke research and therapies. Biochim Biophys Acta Mol Basis Dis 1866(4):165260

Article  CAS  PubMed  Google Scholar 

Becht E et al (2018) Dimensionality reduction for visualizing single-cell data using UMAP. Nat Biotechnol 37:38–44

Article  Google Scholar 

Bonifačić D et al (2016) Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke. Wien Klin Wochenschr 128(1-2):20–27

Article  PubMed  Google Scholar 

Caprio FZ, Sorond FA (2019) Cerebrovascular Disease: Primary and Secondary Stroke Prevention. Med Clin North Am 103(2):295–308

Article  PubMed  Google Scholar 

Castellanos M et al (2003) Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke. Stroke 34(1):40–46

Article  CAS  PubMed  Google Scholar 

Chapman KZ et al (2009) A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke. J Cereb Blood Flow Metab 29(11):1764–1768

Article  PubMed  Google Scholar 

Chavez-Valdez R et al (2012) Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia. Neuroscience 219:192–203

Article  CAS  PubMed  Google Scholar 

Chen AQ et al (2019) Microglia-derived TNF-α mediates endothelial necroptosis aggravating blood brain-barrier disruption after ischemic stroke. Cell Death Dis 10(7):487

Article  PubMed  PubMed Central  Google Scholar 

Cui P et al (2023) Microglia/macrophages require vitamin D signaling to restrain neuroinflammation and brain injury in a murine ischemic stroke model. J Neuroinflammation 20(1):63

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cui Q, Naikoo NA (2019) Modifiable and non-modifiable risk factors in ischemic stroke: a meta-analysis. Afr Health Sci 19(2):2121–2129

Article  PubMed  PubMed Central  Google Scholar 

Davidson SM et al (2020) Mitochondrial and mitochondrial-independent pathways of myocardial cell death during ischaemia and reperfusion injury. J Cell Mol Med 24(7):3795–3806

Article  PubMed  PubMed Central  Google Scholar 

Dichgans M, Pulit SL, Rosand J (2019) Stroke genetics: discovery, biology, and clinical applications. Lancet Neurol 18(6):587–599

Article  PubMed  Google Scholar 

Fann DY et al (2013) Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke. Cell Death Dis 4(9):e790

Article  CAS  PubMed  Google Scholar 

Gribov A et al (2010) SEURAT: visual analytics for the integrated analysis of microarray data. BMC Med Genomics 3:21

Article  PubMed  PubMed Central  Google Scholar 

Gui X et al (2020) Prognosis of Subtypes of Acute Large Artery Atherosclerotic Cerebral Infarction by Evaluation of Established Collateral Circulation. J Stroke Cerebrovasc Dis 29(11):105232

Article  PubMed  Google Scholar 

Guo X et al (2019) Metabolic Profile for Prediction of Ischemic Stroke in Chinese Hypertensive Population. J Stroke Cerebrovasc Dis 28(4):1062–1069

Article  PubMed  Google Scholar 

Han D, Liu H, Gao Y (2020) The role of peripheral monocytes and macrophages in ischemic stroke. Neurol Sci 41(12):3589–3607

Article  PubMed  Google Scholar 

Harari OA, Liao JK (2010) NF-κB and innate immunity in ischemic stroke. Ann N Y Acad Sci 1207:32–40

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hu X et al (2012) Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 43(11):3063–3070

Article  CAS  PubMed  Google Scholar 

Iadecola C, Buckwalter MS, Anrather J (2020) Immune responses to stroke: mechanisms, modulation, and therapeutic potential. J Clin Invest 130(6):2777–2788

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jin S et al (2021) Inference and analysis of cell-cell communication using CellChat. Nat Commun 12(1):1088

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kaczmarek A, Vandenabeele, Krysko DV (2013) Necroptosis: the release of damage-associated molecular patterns and its physiological relevance. Immunity 38(2):209–223

Article  CAS  PubMed  Google Scholar 

Kanazawa M et al (2017) Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. Int J Mol Sci 18(10):2135

Article  PubMed  PubMed Central  Google Scholar 

Kanki H et al (2023) Importance of microRNAs by mRNA-microRNA integration analysis in acute ischemic stroke patients. J Stroke Cerebrovasc Dis 32(9):107277

Article  PubMed  Google Scholar 

Kouwenhoven M et al (2001) Matrix metalloproteinase and cytokine profiles in monocytes over the course of stroke. J Clin Immunol 21(5):365–375

Article  CAS  PubMed  Google Scholar 

Li S et al (2019) Expression Profile and Potential Functions of Circulating Long Noncoding RNAs in Acute Ischemic Stroke in the Southern Chinese Han Population. Front Mol Neurosci 12:290

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luo L, Zhu M, Zhou J (2018) Association between CTSS gene polymorphism and the risk of acute atherosclerotic cerebral infarction in Chinese population: a case-control study. Biosci Rep 38(6):BSR20180586

Article  PubMed  PubMed Central  Google Scholar 

Mabuchi T et al (2000) Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats. Stroke 31(7):1735–1743

Article  CAS  PubMed  Google Scholar 

Maida CD et al (2020) Neuroinflammatory Mechanisms in Ischemic Stroke: Focus on Cardioembolic Stroke, Background, and Therapeutic Approaches. Int J Mol Sci 21(18):6454

Article  CAS  PubMed  PubMed Central  Google Scholar 

Monteiro FL et al (2017) The histone H2A isoform Hist2h2ac is a novel regulator of proliferation and epithelial-mesenchymal transition in mammary epithelial and in breast cancer cells. Cancer Lett 396:42–52

Article  CAS  PubMed  Google Scholar 

Otasek D et al (2019) Cytoscape Automation: empowering workflow-based network analysis. Genome Biol 20(1):185

Article  PubMed  PubMed Central  Google Scholar 

Pawluk H et al (2020) The Role of Selected Pro-Inflammatory Cytokines in Pathogenesis of Ischemic Stroke. Clin Interv Aging 15:469–484

Article  CAS  PubMed  PubMed Central  Google Scholar 

Perego C, Fumagalli S, De Simoni MG (2011) Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice. J Neuroinflammation 8:174

Article  CAS  PubMed  PubMed Central  Google Scholar 

Petrovic-Djergovic D, Goonewardena SN, Pinsky DJ (2016) Inflammatory Disequilibrium in Stroke. Circ Res 119(1):142–158

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rigden DJ, Fernández XM (2021) The 2021 Nucleic Acids Research database issue and the online molecular biology database collection. Nucleic Acids Res 49(D1):D1–d9

Article  CAS  PubMed  Google Scholar 

Ritchie ME et al (2015) limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43(7):e47

Article  PubMed  PubMed Central  Google Sc