Adamson GD, de Mouzon J, Chambers GM, Zegers-Hochschild F, Mansour R, Ishihara O, Banker M, Dyer S. International committee for monitoring assisted reproductive technology: world report on assisted reproductive technology, 2011. Fertil Steril. 2018;110(6):1067–80.

Article  PubMed  Google Scholar 

Coughlan C, Ledger W, Wang Q, Liu F, Demirol A, Gurgan T, Cutting R, Ong K, Sallam H, Li TC. Recurrent implantation failure: definition and management. Reprod Biomed Online. 2014;28(1):14–38.

Article  CAS  PubMed  Google Scholar 

Kushnir VA, Barad DH, Albertini DF, Darmon SK, Gleicher N. Systematic review of worldwide trends in assisted reproductive technology 2004–2013. Reprod Biol Endocrinol. 2017;15(1):6.

Article  PubMed  PubMed Central  Google Scholar 

Dyer S, Chambers GM, de Mouzon J, Nygren KG, Zegers-Hochschild F, Mansour R, Ishihara O, Banker M, Adamson GD. International committee for monitoring assisted reproductive technologies world report: assisted reproductive technology 2008, 2009 and 2010. Hum Reprod. 2016;31(7):1588–609.

Article  CAS  PubMed  Google Scholar 

Gnainsky Y, Dekel N, Granot I. Implantation: mutual activity of sex steroid hormones and the immune system guarantee the maternal-embryo interaction. Semin Reprod Med. 2014;32(5):337–45.

Article  CAS  PubMed  Google Scholar 

Cha J, Sun X, Dey SK. Mechanisms of implantation: strategies for successful pregnancy. Nat Med. 2012;18(12):1754–67.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nimbkar-Joshi S, Rosario G, Katkam RR, Manjramkar DD, Metkari SM, Puri CP, Sachdeva G. Embryo-induced alterations in the molecular phenotype of primate endometrium. J Reprod Immunol. 2009;83(1–2):65–71.

Article  CAS  PubMed  Google Scholar 

Valdes CT, Schutt A, Simon C. Implantation failure of endometrial origin: it is not pathology, but our failure to synchronize the developing embryo with a receptive endometrium. Fertil Steril. 2017;108(1):15–8.

Article  PubMed  Google Scholar 

Macklon N. Recurrent implantation failure is a pathology with a specific transcriptomic signature. Fertil Steril. 2017;108(1):9–14.

Article  PubMed  Google Scholar 

Saxtorph MH, Hallager T, Persson G, Petersen KB, Eriksen JO, Larsen LG, Hviid TV, Macklon N. Assessing endometrial receptivity after recurrent implantation failure: a prospective controlled cohort study. Reprod Biomed Online. 2020;41(6):998–1006.

Article  CAS  PubMed  Google Scholar 

Wang L, Huang X, Li X, Lv F, He X, Pan Y, Wang L, Zhang X. Efficacy evaluation of low-dose aspirin in IVF/ICSI patients evidence from 13 RCTs: A systematic review and meta-analysis. Medicine (Baltimore). 2017;96(37):e7720.

Article  CAS  PubMed  Google Scholar 

Davar R, Janati S, Mohseni F, Khabazkhoob M, Asgari S. A comparison of the effects of transdermal estradiol and estradiol valerate on endometrial receptivity in frozen-thawed embryo transfer cycles: a randomized clinical trial. J Reprod Infertil. 2016;17(2):97–103.

PubMed  PubMed Central  Google Scholar 

Zhang L, Xu WH, Fu XH, Huang QX, Guo XY, Zhang L, Li SS, Zhu J, Shu J. Therapeutic role of granulocyte colony-stimulating factor (G-CSF) for infertile women under in vitro fertilization and embryo transfer (IVF-ET) treatment: a meta-analysis. Arch Gynecol Obstet. 2018;298(5):861–71.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xie H, Zeng H, He D, Liu N. Effect of intrauterine perfusion of human chorionic gonadotropin before embryo transfer after two or more implantation failures: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2019;243:133–8.

Article  PubMed  Google Scholar 

Benkhalifa M, Joao F, Duval C, Montjean D, Bouricha M, Cabry R, Belanger M-C, Bahri H, Miron P, Benkhalifa M. Endometrium Immunomodulation to Prevent Recurrent Implantation Failure in Assisted Reproductive Technology. Int J Mol Sci. 2022;23(21):12787.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pourmoghadam Z, Abdolmohammadi-Vahid S, Pashazadeh F, Aghebati-Maleki L, Ansari F, Yousefi M. Efficacy of intrauterine administration of autologous peripheral blood mononuclear cells on the pregnancy outcomes in patients with recurrent implantation failure: A systematic review and meta-analysis. J Reprod Immunol. 2020;137:103077.

Article  CAS  PubMed  Google Scholar 

Aleyasin A, Abediasl Z, Nazari A, Sheikh M. Granulocyte colony-stimulating factor in repeated IVF failure, a randomized trial. Reproduction (Cambridge, England). 2016;151(6):637–42.

Article  CAS  PubMed  Google Scholar 

Kamath MS, Kirubakaran R, Sunkara SK. Granulocyte-colony stimulating factor administration for subfertile women undergoing assisted reproduction. Cochrane Database Syst Rev. 2020;1(1):CD013226.

PubMed  Google Scholar 

Kalem Z, Namli Kalem M, Bakirarar B, Kent E, Makrigiannakis A, Gurgan T. Intrauterine G-CSF administration in recurrent implantation failure (RIF): an Rct. Sci Rep. 2020;10(1):5139.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Danhof NA, Wang R, van Wely M, van der Veen F, Mol BWJ, Mochtar MH. IUI for unexplained infertility-a network meta-analysis. Hum Reprod Update. 2020;26(1):1–15.

Article  CAS  PubMed  Google Scholar 

Wu H, Zhang S, Lin X, Wang S, Zhou P. Luteal phase support for in vitro fertilization/intracytoplasmic sperm injection fresh cycles: a systematic review and network meta-analysis. Reprod Biol Endocrinol. 2021;19(1):103.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang Y, Zhang C, Shu J, Guo J, Chang HM, Leung PCK, Sheng JZ, Huang H. Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis. Hum Reprod Update. 2020;26(2):247–63.

Article  CAS  PubMed  Google Scholar 

Wang Z, Ren CE, Ren W, Shi H. The frozen⁃thawed embryo transfer(FET) outcomes of the patients with repeated embryo implantationfailure after intrauterine injection of dexamethasone sodium phosphate. J Prac Med. 2021;37(08):1064–7. %@ 1006-5725 %L 1044-1193/R %W CNKI.

Google Scholar 

Santibanez A, Garcia J, Pashkova O, Colin O, Castellanos G, Sanchez AP, De la Jara JF. Effect of intrauterine injection of human chorionic gonadotropin before embryo transfer on clinical pregnancy rates from in vitro fertilisation cycles: a prospective study. Reprod Biol Endocrinol. 2014;12:9.

Article  PubMed  PubMed Central  Google Scholar 

Huang P, Wei L, Li X. A study of intrauterine infusion of human chorionic gonadotropin (hCG) before frozen-thawed embryo transfer after two or more implantation failures. Gynecol Endocrinol. 2017;33(1):67–9.

Article  CAS  PubMed  Google Scholar 

Shanfei Z, Wenling Z, Xinru G. Effects of intrauterine infusion of HCG on pregnancy outcome in patients with repeated implantion failure in freeze-thaw embryo transfer cycles. J Chin Prescription Drug. 2020;18(11):8–10. %@ 1671-1945X %L 1644-1549/T %W CNKI.

Google Scholar 

Wang M, Deng H, Hong Y. Intrauterine injection of human chorionic gonadotropin improves pregnancy outcome in patients with repeated implantation failure in frozen-thawed embryo transfer. J Cent South Univ (Med Sci). 2019;44(11):1247–51. %@ 1672-7347 %L 1243-1427/R %W CNKI.

Google Scholar 

Nobijari FF, Arefi SS, Moini A, Taheripanah R, Fazeli E, Kharazi H, Hosseini SZ, Hosseini A, Valojerdi MR, Copin H, et al. Endometrium immunomodulation by intrauterine insemination administration of treated peripheral blood mononuclear cell prior frozen/thawed embryos in patients with repeated implantation failure. Zygote. 2019;27(4):214–8.

Article  CAS  PubMed  Google Scholar 

Yu N, Zhang B, Xu M, Wang S, Liu R, Wu J, Yang J, Feng L. Intrauterine administration of autologous peripheral blood mononuclear cells (PBMCs) activated by HCG improves the implantation and pregnancy rates in patients with repeated implantation failure: a prospective randomized study. Am J Reprod Immunol. 2016;76(3):212–6.

Article  CAS  PubMed  Google Scholar 

Madkour A, Bouamoud N, Louanjli N, Kaarouch I, Copin H, Benkhalifa M, Sefrioui O. Intrauterine insemination of cultured peripheral blood mononuclear cells prior to embryo transfer improves clinical outcome for patients with repeated implantation failures. Zygote. 2016;24(1):58–69.

Article  CAS  PubMed  Google Scholar 

Xu H, Tan X-J, Huang X-H. Effect of intrauterine perfusion of peripheral blood mononuclear cells on patients with repeated implant failure. J Chin Prescription Drug. 2021;19(06):172–4.

Google Scholar 

Lei L, Zhang Y, Lu L. Effect of intrauterine perfusion of autologous peripheral blood mononuclear cell of women with repeated implantation failure in IVF-ET on their pregnancy outcomes. Chin J Fam Plan. 2021;29(02):251–4. %@ 1004-8189 %L 1011-4550/R %W CNKI.

Google Scholar 

Zhao H. Analysis of the effect of lymphocyte on pregnancy outcome in patients with repeated implant failure. Clin Res. 2020;28(10):1–2. %@ 2096-1278 %L 2061-1502/R %W CNKI.

CAS  Google Scholar 

Xiang Y, Yu G, Song Y, Li Y, Wan L, Ma L, Tan L. Effects of autologous peripheral blood mononuclear cells on endometrial receptivity marker molecules and pregnancy outcome after freeze-thaw embryo transfer in patients with repeated implantation failure. J Pract Obstet Gynecol. 2019;35(03):347–51. %@ 1005-2216 %L 1021-1332/R.

CAS  Google Scholar 

Lu X, Qiao P, Peng Y, Shi H, Ren C. Pregnancy outcomes and serum TNF-αlevels in patients withrepeated implantation failure treated with intrauterine perfusion of PBMCs. Acta Acad Med Weifang. 2019;41(03):25–227. %@ 1004-3101 %L 1037-1195/R.

CAS  Google Scholar 

Lin Q, Lian R, Chen X, Liu C, Diao L, Huang C, Chen X, Zeng Y, Liang P. Effect of intrauterine administration of peripheral blood mononuclear cells on the pregnancy outcome of patients with recurrent implantation failure. J Reprod Med. 2013;22(12):922–6. %@ 1004-3845 %L 1011-4645/R %W CNKI.

Google Scholar 

Davari-Tanha F, Shahrokh Tehraninejad E, Ghazi M, Shahraki Z. The role of G-CSF in recurrent implantation failure: A randomized double blind placebo control trial. Int J Reprod Biomed. 2016;14(12):737–42.

PubMed  PubMed Central  Google Scholar 

Pourmoghadam Z, Soltani-Zangbar MS, Sheikhansari G, Azizi R, Eghbal-Fard S, Mohammadi H, Siahmansouri H, Aghebati-Maleki L, Danaii S, Mehdizadeh A, et al. Intrauterine administration of autologous hCG- activated peripheral blood mononuclear cells improves pregnancy outcomes in patients with recurrent imp