Adjanohoun E, Adjakidje V, Ahyi MRA, Akpagana K et al (1986) Contribution aux études ethnobotaniques et floristiques au Togo. Agence de coopération culturelle et technique (ACCT), Paris, p 671

Google Scholar 

Anderson DMW (1985) Gums and resins, and factors influencing their economic development. In: Wickens, G.E., Goodin, J.R., Field, D.V. (eds) Plants for Arid Lands. Springer, Dordrecht, pp 343–356. https://doi.org/10.1007/978-94-011-6830-4_25

Angeloni C, Malaguti M, Barbalace MC, Hrelia S (2017) Bioactivity of olive oil phenols in neuroprotection. Int J Mol Sci 18(11):2230. https://doi.org/10.3390/ijms18112230

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arakawa M, Ushimaru N, Osada N, Oda T, Ishige K, Ito Y (2006) N-acetylcysteine selectively protects cerebellar granule cells from 4-hydroxynonenal-induced cell death. Neurosci Res 55(3):255–263. https://doi.org/10.1016/j.neures.2006.03.008

Article  CAS  PubMed  Google Scholar 

Arias-Sánchez RA, Torner L, Fenton Navarro B (2023) Polyphenols and neurodegenerative diseases: potential effects and mechanisms of neuroprotection. Molecules 28(14):5415. https://doi.org/10.3390/molecules28145415

Article  CAS  PubMed  PubMed Central  Google Scholar 

Atakpama W, Batawila K, Dourma M, Pereki H, Wala K, Dimobe K, Gbeassor M (2012) Ethnobotanical knowledge of Sterculia setigera Del. in the Sudanian zone of Togo (West Africa). Int Sch Res Notices 723157. https://doi.org/10.5402/2012/723157

Atanasov AG, Zotchev SB, Dirsch VM, Supuran CT (2021) Natural products in drug discovery: advances and opportunities. Nat Rev Drug Discov 20(3):200–216. https://doi.org/10.1038/s41573-020-00114-z

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bahdoudi S, Ghouili I, Hmiden M, Do Rego JL, Lefranc B, Leprince J, Vaudry D (2018) Neuroprotective effects of the gliopeptide ODN in an in vivo model of Parkinson’s disease. Cell Mol Life Sci 75:2075–2091. https://doi.org/10.1007/s00018-017-2727-2

Article  CAS  PubMed  Google Scholar 

Bellavite P (2023) Neuroprotective potentials of flavonoids: experimental studies and mechanisms of action. Antioxidants 12(2):280. https://doi.org/10.3390/antiox12020280

Article  CAS  PubMed  PubMed Central  Google Scholar 

Benzie IF, Strain JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Anal Biochem 239(1):70–76. https://doi.org/10.1006/abio.1996.0292

Article  CAS  PubMed  Google Scholar 

Blois M (1958) Antioxidant determinations by the use of a stable free radical. Nature 181:1199–1200. https://doi.org/10.1038/1811199a0

Article  CAS  Google Scholar 

Bose S, Datta R, Kirlin WG (2021) Toxicity studies related to medicinal plants. In: Mandal, S.C., Chakraborty, R., Sen, S. (eds) Evidence based validation of traditional medicines. Springer, Singapore. pp 621–647. https://doi.org/10.1007/978-981-15-8127-4_30

Botia B, Jolivel V, Burel D, Le Joncour V, Roy V, Naassila M, Bénard M, Fournier A, Vaudry H, Vaudry D (2011) Neuroprotective effects of PACAP against ethanol-induced toxicity in the developing rat cerebellum. Neurotox Res 19:423–434. https://doi.org/10.1007/s12640-010-9186-y

Article  CAS  PubMed  Google Scholar 

Chambers M, Maclean B, Burke R et al (2012) A cross-platform toolkit for mass spectrometry and proteomics. Nat Biotechnol 30:918–920. https://doi.org/10.1038/nbt.2377

Article  CAS  PubMed  PubMed Central  Google Scholar 

Corbière A, Walet-Balieu ML, Chan P, Basille-Dugay M, Hardouin J, Vaudry D (2018) A peptidomic approach to characterize peptides involved in cerebellar cortex development leads to the identification of the neurotrophic effects of nociceptin. Mol Cell Proteomics 17(9):1737–1749. https://doi.org/10.1074/mcp.RA117.000184

Article  PubMed  PubMed Central  Google Scholar 

Cregan SP, MacLaurin JG, Craig CG, Robertson GS, Nicholson DW, Park DS, Slack RS (1999) Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons. J Neurosci 19(18):7860–7869. https://doi.org/10.1523/JNEUROSCI.19-18-07860.1999

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dohou R, Yamni K, Tahrouch S, Hassani LI, Badoc A, Gmira N (2003) Screening phytochimique d’une endémique iberomarocaine. Thymelaea Lythroides Bull Soc Pharm Bordx 142(1/4):61–78

Google Scholar 

Eccles JC (1967) Circuits in the cerebellar control of movement. Proc Natl Acad Sci USA 58(1):336–343. https://doi.org/10.1073/pnas.58.1.336

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fan Z, Wang Y, Yang M, Cao J, Khan A, Cheng G (2020) UHPLC-ESI-HRMS/MS analysis on phenolic compositions of different E Se tea extracts and their antioxidant and cytoprotective activities. Food Chem 318:126512. https://doi.org/10.1016/j.foodchem.2020.126512

Article  CAS  PubMed  Google Scholar 

Figueira I, Garcia G, Pimpão RC et al (2017) Polyphenols journey through blood-brain barrier towards neuronal protection. Sci Rep 7:11456. https://doi.org/10.1038/s41598-017-11512-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ghozy S, Reda A, Varney J, Elhawary AS, Shah J, Murry K, Kallmes DF (2022) Neuroprotection in acute ischemic stroke: a battle against the biology of nature. Front Neurol 13:870141. https://doi.org/10.3389/fneur.2022.870141

Article  PubMed  PubMed Central  Google Scholar 

Götz ME, Ahlbom E, Zhivotovsky B, Blum-Degen D, Oettel M, Römer W, Ceccatelli S (1999) Radical scavenging compound J 811 inhibits hydrogen peroxide-induced death of cerebellar granule cells. J Neurosci Res 56(4):420–426. https://doi.org/10.1002/(SICI)1097-4547(19990515)56:4%3C420::AID-JNR9%3E3.0.CO;2-P

Article  PubMed  Google Scholar 

Hashim JF, Vichitphan S, Boonsiri P, Vichitphan K (2021) Neuroprotective assessment of Moringa oleifera leaves extract against oxidative-stress-induced cytotoxicity in SHSY5Y neuroblastoma cells. Plants (basel) 10(5):889. https://doi.org/10.3390/plants10050889

Article  CAS  Google Scholar 

Hirst EL, Hough L, Jones JKN (1949) Composition of the gum of Sterculia setigera: occurrence of D-tagatose in nature. Nature 163(4135):177–177. https://doi.org/10.1038/163177b0

Article  CAS  PubMed  Google Scholar 

Hiskens MI (2022) Targets of neuroprotection and review of pharmacological interventions in traumatic brain injury. J Pharmacol Exp Ther 382(2):149–166. https://doi.org/10.1124/jpet.121.001023

Article  CAS  PubMed  Google Scholar 

Holloway KN, Douglas JC, Rafferty TM, Majewska AK, Kane CJ, Drew PD (2023) Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: focus on disease onset. Front Neurosci 17:1154637. https://doi.org/10.3389/fnins.2023.1154637

Article  PubMed  PubMed Central  Google Scholar 

Hu S, Mak S, Zuo X, Li H, Wang Y, Han Y (2018) Neuroprotection against MPP+-induced cytotoxicity through the activation of PI3-K/Akt/GSK3β/MEF2D signaling pathway by rhynchophylline, the major tetracyclic oxindole alkaloid isolated from Uncaria rhynchophylla. Front Pharmacol 9:768. https://doi.org/10.3389/fphar.2018.00768

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ikonomidou C, Bittigau P, Ishimaru MJ, Wozniak DF, Koch C, Genz K, Price MT, Stefovska V, Hörster F, Tenkova T, Dikranian K, Olney JW (2000) Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science 287(5455):1056–1060. https://doi.org/10.1126/science.287.5455.1056

Article  CAS  PubMed  Google Scholar 

Iwuanyanwu VU, Banjo OW, Babalola KT, Olajide OA (2023) Neuroprotection by Alstonia boonei De Wild., Anacardium occidentale L., Azadirachta indica A. Juss. and Mangifera indica L. J Ethnopharmacol 310:116390. https://doi.org/10.1016/j.jep.2023.116390

Jayamuthunagai J, Srisowmeya G, Chakravarthy M, Gautam P (2017) D-Tagatose production by permeabilized and immobilized Lactobacillus plantarum using whey permeate. Bioresour Technol 235:250–255. https://doi.org/10.1016/j.biortech.2017.03.123

Article  CAS  PubMed  Google Scholar 

Jin B, Liu J, Gao D, Xu Y, He L, Zang Y, Li N, Lin D (2020) Detailed studies on the anticancer action of rosmarinic acid in human Hep-G2 liver carcinoma cells: evaluating its effects on cellular apoptosis, caspase activation and suppression of cell migration and invasion. J BUON 25(3):1383–1389

PubMed  Google Scholar 

Kaddour H, Hamdi Y, Vaudry D, Basille M, Desrues L, Leprince J, Castel H, Vaudry H, Tonon MC, Amri M, Masmoudi-Kouki O (2013) The octadecaneuropeptide ODN prevents 6-hydroxydopamine-induced apoptosis of cerebellar granule neurons through a PKC-MAPK-dependent pathway. J Neurochem 125(4):620–633. https://doi.org/10.1111/jnc.12140

Article  CAS  PubMed  Google Scholar 

Kantati YT, Kodjo KM, Dogbeavou KS, Vaudry D, Leprince J, Gbeassor M (2016) Ethnopharmacological survey of plant species used in folk medicine against central nervous system disorders in Togo. J Ethnopharmacol 181:214–220. https://doi.org/10.1016/j.jep.2016.02.006

Article  PubMed  Google Scholar 

Kuida K, Zheng T, Na S, Kuan CY, Yang D, Karasuyama H, Rakic P, Flavell RA (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384:368–372. https://doi.org/10.1038/384368a0

Article  CAS  PubMed  Google Scholar 

Kumar A, LaVoie HA, DiPette DJ, Singh US (2013) Ethanol neurotoxicity in the developing cerebellum: underlying mechanisms and implications. Brain Sci 3(2):941–963. https://doi.org/10.3390/brainsci3020941

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lacaille H, Duterte-Boucher D, Liot D, Vaudry H, Naassila M, Vaudry D (2015) Comparison of the deleterious effects of binge drinking-like alcohol exposure in adolescent and adult mice. J Neurochem 132(6):629–641. https://doi.org/10.1111/jnc.13020

Article  CAS  PubMed