Agostini M, Fasolato C (2016) When, where and how? Focus on neuronal calcium dysfunctions in Alzheimer’s Disease. Cell Calcium 60:289–298. https://doi.org/10.1016/j.ceca.2016.06.008

Article  CAS  PubMed  Google Scholar 

Bajrai LH, Sohrab SS, Alandijany TA et al (2021) Gene expression profiling of early acute febrile stage of dengue infection and its comparative analysis with Streptococcus pneumoniae infection. Front Cell Infect Microbiol 11. https://doi.org/10.3389/fcimb.2021.707905

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baleriola J, Walker CA, Jean YY et al (2014) Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions. Cell 158:1159–1172. https://doi.org/10.1016/j.cell.2014.07.001

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bezprozvanny I, Mattson MP (2008) Neuronal calcium mishandling and the pathogenesis of Alzheimer’s disease. Trends Neurosci 31:454–463. https://doi.org/10.1016/j.tins.2008.06.005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brancaccio D, Tetta C, Gallieni M et al (2002) Inflammation, CRP, calcium overload and a high calcium-phosphate product: a “liaison dangereuse.” Nephrol Dial Transplant 17:201–203. https://doi.org/10.1093/ndt/17.2.201

Article  PubMed  Google Scholar 

Briggs CA, Chakroborty S, Stutzmann GE (2017) Emerging pathways driving early synaptic pathology in Alzheimer’s disease. Biochem Biophys Res Commun 483:988–997. https://doi.org/10.1016/j.bbrc.2016.09.088

Article  CAS  PubMed  Google Scholar 

Calsolaro V, Edison P (2016) Neuroinflammation in Alzheimer’s disease: current evidence and future directions. Alzheimers Dement 12:719–732. https://doi.org/10.1016/j.jalz.2016.02.010

Article  PubMed  Google Scholar 

Chang KA, Kim SH, Sakaki Y et al (1999) Inhibition of the NGF and IL-1beta-induced expression of Alzheimer’s amyloid precursor protein by antisense oligonucleotides. J Mol Neurosci 12:69–74. https://doi.org/10.1385/jmn:12:1:69

Article  CAS  PubMed  Google Scholar 

Chen K, Yang LN, Lai C et al (2020) Role of Grina/Nmdara1 in the central nervous system diseases. Curr Neuropharmacol 18:861–867. https://doi.org/10.2174/1570159X18666200303104235

Article  PubMed  PubMed Central  Google Scholar 

Copenhaver PF, Anekonda TS, Musashe D et al (2011) A translational continuum of model systems for evaluating treatment strategies in Alzheimer’s disease: isradipine as a candidate drug. Dis Model Mech 4:634–648. https://doi.org/10.1242/dmm.006841

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cramer E, Lenz U (2010) Association of progressively type-II censored order statistics. Journal of Statistical Planning and Inference 140:576–583. https://doi.org/10.1016/j.jspi.2009.07.020

Article  Google Scholar 

Crossley CA, Rajani V, Yuan Q (2023) Modulation of L-type calcium channels in Alzheimer’s disease: a potential therapeutic target. Comput Struct Biotechnol J 21:11–20. https://doi.org/10.1016/j.csbj.2022.11.049

Article  CAS  PubMed  Google Scholar 

Fu WY, Ip NY (2023) The role of genetic risk factors of Alzheimer’s disease in synaptic dysfunction. Semin Cell Dev Biol 139:3–12. https://doi.org/10.1016/j.semcdb.2022.07.011

Article  CAS  PubMed  Google Scholar 

Gentleman RC, Carey VJ, Bates DM et al (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5:R80. https://doi.org/10.1186/gb-2004-5-10-r80

Article  PubMed  PubMed Central  Google Scholar 

Hickman SE, Allison EK, El Khoury J (2008) Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer’s disease mice. J Neurosci 28:8354–8360. https://doi.org/10.1523/JNEUROSCI.0616-08.2008

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanehisa M (2019) Toward understanding the origin and evolution of cellular organisms. Protein Sci 28:1947–1951. https://doi.org/10.1002/pro.3715

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanehisa M, Goto S (2000) KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28:27–30. https://doi.org/10.1093/nar/28.1.27

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanehisa M, Furumichi M, Sato Y et al (2023) KEGG for taxonomy-based analysis of pathways and genomes. Nucleic Acids Res 51:D587–D592. https://doi.org/10.1093/nar/gkac963

Article  CAS  PubMed  Google Scholar 

Khan S, Barve KH, Kumar MS (2020) Recent advancements in pathogenesis, diagnostics and treatment of Alzheimer’s disease. Curr Neuropharmacol 18:1106–1125. https://doi.org/10.2174/1570159x18666200528142429

Article  CAS  PubMed  PubMed Central  Google Scholar 

Korkotian E, Oni-Biton E, Segal M (2017) The role of the store-operated calcium entry channel Orai1 in cultured rat hippocampal synapse formation and plasticity. J Physiol 595:125–140. https://doi.org/10.1113/JP272645

Article  CAS  PubMed  Google Scholar 

Lefever S, Anckaert J, Volders PJ et al (2017) decodeRNA- predicting non-coding RNA functions using guilt-by-association. Database (Oxford) 2017. https://doi.org/10.1093/database/bax042

Miller AT, Dahlberg C, Sandberg ML et al (2015) Inhibition of the inositol kinase Itpkb augments calcium signaling in lymphocytes and reveals a novel strategy to treat autoimmune disease. PLoS ONE 10:e01310710 https://doi.org/10.1371/journal.pone.0131071

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moradi Majd R, Mayeli M, Rahmani F (2020) Pathogenesis and promising therapeutics of Alzheimer disease through eIF2alpha pathway and correspondent kinases. Metab Brain Dis 35:1241–1250. https://doi.org/10.1007/s11011-020-00600-8

Article  CAS  PubMed  Google Scholar 

Pan XD, Zhu YG, Lin N et al (2011) Microglial phagocytosis induced by fibrillar beta-amyloid is attenuated by oligomeric beta-amyloid: implications for Alzheimer’s disease. Mol Neurodegener 6:45. https://doi.org/10.1186/1750-1326-6-45

Article  CAS  PubMed  PubMed Central  Google Scholar 

Paris D, Bachmeier C, Patel N et al (2011) Selective antihypertensive dihydropyridines lower Abeta accumulation by targeting both the production and the clearance of Abeta across the blood-brain barrier. Mol Med 17:149–162. https://doi.org/10.2119/molmed.2010.00180

Article  CAS  PubMed  Google Scholar 

Pchitskaya E, Popugaeva E, Bezprozvanny I (2018) Calcium signaling and molecular mechanisms underlying neurodegenerative diseases. Cell Calcium 70:87–94. https://doi.org/10.1016/j.ceca.2017.06.008

Article  CAS  PubMed  Google Scholar 

Rinn JL, Chang HY (2012) Genome regulation by long noncoding RNAs. Annu Rev Biochem 81:145–166. https://doi.org/10.1146/annurev-biochem-051410-092902

Article  CAS  PubMed  Google Scholar 

Ryan KC, Ashkavand Z, Norman KR (2020) The role of mitochondrial calcium homeostasis in Alzheimer’s and related diseases. Int J Mol Sci. https://doi.org/10.3390/ijms21239153

Article  PubMed  PubMed Central  Google Scholar 

Ryu JC, Zimmer ER, Rosa-Neto P et al (2019) Consequences of metabolic disruption in Alzheimer’s disease pathology. Neurotherapeutics 16:600–610. https://doi.org/10.1007/s13311-019-00755-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schwartz L, Peres S, Jolicoeur M et al (2020) Cancer and Alzheimer’s disease: intracellular pH scales the metabolic disorders. Biogerontology 21:683–694. https://doi.org/10.1007/s10522-020-09888-6

Article  CAS  PubMed  Google Scholar 

Stygelbout V, Leroy K, Pouillon V et al (2014) Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology. Brain 137:537–552. https://doi.org/10.1093/brain/awt344

Article  PubMed  Google Scholar 

Subramanian A, Tamayo P, Mootha VK et al (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102:15545–15550. https://doi.org/10.1073/pnas.0506580102

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun S, Zhang H, Liu J et al (2014) Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice. Neuron 82:79–93. https://doi.org/10.1016/j.neuron.2014.02.019

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tropea MR, Gulisano W, Vacanti V et al (2022) Nitric oxide/cGMP/CREB pathway and amyloid-beta crosstalk: from physiology to Alzheimer’s disease. Free Radic Biol Med 193:657–668. https://doi.org/10.1016/j.freeradbiomed.2022.11.022