Characterization and Determinants of Long-Term Immune Recovery Under Suppressive Antiretroviral Therapy

aDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland;

bInstitute of Medical Virology, University of Zurich, Zurich, Switzerland;

cDepartment of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland;

dDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland;

eDivision of Infectious Diseases, Lausanne University Hospital, Lausanne, Switzerland;

fClinic for Infectious Diseases, Cantonal Hospital Olten, Olten, Switzerland;

gDivision of Infectious Diseases, Geneva University Hospital, Geneva, Switzerland;

hDivision of Infectious Diseases, Ente Ospedaliero Cantonale, Lugano, Switzerland;

iUniversity of Geneva and University of Southern Switzerland, Lugano, Switzerland;

jDivision of Infectious Diseases, Cantonal Hospital St. Gallen, St. Gallen, Switzerland; and

kCollegium Helveticum, Zurich, Switzerland.

Correspondence to: Marco Labarile, MSc, University Hospital Zurich, Rämistrasse 100, Zurich, Switzerland 8091 (e-mail: [email protected]).

Supported within the framework of the Swiss HIV Cohort Study, supported by the Swiss National Science Foundation (Grant #201369), by SHCS project #829 and by the SHCS research foundation. RDK has been supported by the Swiss National Science Foundation (Grant BSSGI0_155851).

H.F.G. has received grants from the Swiss National Science Foundation; Swiss HIV Cohort Study; Yvonne Jacob Foundation; University of Zurich's Clinical Research Priority Program, viral disease; Zurich Primary HIV Infection; Systems.X; National Institutes of Health; Gilead Sciences; and Roche; and personal fees from Merck, Gilead Sciences, ViiV, GSK, Janssen, Johnson and Johnson and Novartis, for consultancy or DSMB membership and a travel grant from Gilead. D.L.B. reports honoraria paid to himself as a consultant for Gilead, ViiV, and Merck.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jaids.com).

T.T. and M.L. contributed equally.

C.P., H.F.G., and R.D.K. contributed equally.

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