Patterns of comorbidities in patients with atrial fibrillation and impact on management and long-term prognosis: an analysis from the Prospective Global GLORIA-AF Registry

Johnston MC, Crilly M, Black C, Prescott GJ, Mercer SW. Defining and measuring multimorbidity: a systematic review of systematic reviews. Eur J Pub Health. 2019;29:182–9.

Article  Google Scholar 

Wu J, Nadarajah R, Nakao YM, Nakao K, Wilkinson C, Mamas MA, et al. Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3·4 million individuals. The Lancet Regional Health - Europe. 2022;17:100386.

Article  PubMed  PubMed Central  Google Scholar 

Jani BD, Nicholl BI, McQueenie R, Connelly DT, Hanlon P, Gallacher KI, et al. Multimorbidity and co-morbidity in atrial fibrillation and effects on survival: findings from UK Biobank cohort. Europace. 2018;20 FI_3:f329–36.

Article  Google Scholar 

Proietti M, Esteve-Pastor MA, Rivera-Caravaca JM, Roldán V, Roldán Rabadán I, Muñiz J, et al. Relationship between multimorbidity and outcomes in atrial fibrillation. Exp Gerontol. 2021;153:111482.

Article  CAS  PubMed  Google Scholar 

Kotalczyk A, Guo Y, Wang Y, Lip GYH. Impact of multimorbidity and polypharmacy on clinical outcomes of elderly Chinese patients with atrial fibrillation. J Clin Med. 2022;11:1370.

Article  PubMed  PubMed Central  Google Scholar 

Romiti GF, Proietti M, Bonini N, Ding WY, Boriani G, Huisman MV, et al. Clinical complexity domains, anticoagulation, and outcomes in patients with atrial fibrillation: a report from the GLORIA-AF registry phase II and III. Thromb Haemost. 2022;122:2030–41.

Article  PubMed  Google Scholar 

Krijthe BP, Kunst A, Benjamin EJ, Lip GYH, Franco OH, Hofman A, et al. Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060. Eur Heart J. 2013;34:2746–51.

Article  PubMed  PubMed Central  Google Scholar 

Nicolaus S, Crelier B, Donzé JD, Aubert CE. Definition of patient complexity in adults: a narrative review. Journal of Multimorbidity and Comorbidity. 2022;12:263355652210812.

Article  Google Scholar 

Corazza GR, Formagnana P, Lenti MV. Bringing complexity into clinical practice: An internistic approach. Eur J Intern Med. 2019;61:9–14.

Article  PubMed  Google Scholar 

Romiti GF, Proietti M, Vitolo M, Bonini N, Fawzy AM, Ding WY, et al. Clinical complexity and impact of the ABC (atrial fibrillation better care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry. BMC Med. 2022;20:326.

Article  PubMed  PubMed Central  Google Scholar 

Mori M, Krumholz HM, Allore HG. Using latent class analysis to identify hidden clinical phenotypes. JAMA. 2020;324:700–1.

Article  PubMed  Google Scholar 

Vermunt JK, Magidson J. Latent class cluster analysis. Applied Latent Class Analysis. 2009:89–106.

Larsen FB, Pedersen MH, Friis K, Gluèmer C, Lasgaard M. A latent class analysis of multimorbidity and the relationship to socio-demographic factors and health-related quality of life. A National Population-Based Study of 162,283 Danish Adults. PLoS One. 2017;12:e0169426.

Article  PubMed  PubMed Central  Google Scholar 

Whitson HE, Johnson KS, Sloane R, Cigolle CT, Pieper CF, Landerman L, et al. Identifying patterns of multimorbidity in older Americans: application of latent class analysis. J Am Geriatr Soc. 2016;64:1668.

Article  PubMed  PubMed Central  Google Scholar 

Park B, Lee HA, Park H. Use of latent class analysis to identify multimorbidity patterns and associated factors in Korean adults aged 50 years and older. PLoS One. 2019;14:e0216259.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lip GYH, Kotalczyk A, Teutsch C, Diener H-C, Dubner SJ, Halperin JL, et al. Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry. Clin Res Cardiol. 2022;111:560–73.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huisman MV, Teutsch C, Lu S, Diener H-C, Dubner SJ, Halperin JL, et al. Dabigatran versus vitamin K antagonists for atrial fibrillation in clinical practice: final outcomes from phase III of the GLORIA-AF registry. Clin Res Cardiol 2022;111:1–12.

Huisman MV, Lip GYH, Diener HC, Dubner SJ, Halperin JL, Ma CS, et al. Design and rationale of global registry on long-term oral antithrombotic treatment in patients with atrial fibrillation: a global registry program on long-term oral antithrombotic treatment in patients with atrial fibrillation. Am Heart J. 2014;167:329–34.

Article  PubMed  Google Scholar 

Mazurek M, Teutsch C, Diener HC, Dubner SJ, Halperin JL, Ma CS, et al. Safety and effectiveness of dabigatran at 2 years: final outcomes from phase II of the GLORIA-AF registry program. Am Heart J. 2019;218:123–7.

Article  PubMed  Google Scholar 

Paquette M, França LR, Teutsch C, Diener HC, Lu S, Dubner SJ, et al. Dabigatran persistence and outcomes following discontinuation in atrial fibrillation patients from the GLORIA-AF registry. Am J Cardiol. 2020;125:383–91.

Article  CAS  PubMed  Google Scholar 

Linzer DA, Lewis JB. poLCA: an R package for polytomous variable latent class analysis. J Stat Softw. 2011;42:1–29.

Article  Google Scholar 

Weller BE, Bowen NK, Faubert SJ. Latent class analysis: a guide to best practice. J Black Psychol. 2020;46:287–311.

Article  Google Scholar 

Proietti M, Romiti GF, Corica B, Mei DA, Bonini N, Vitolo M, et al. Features of clinical complexity in European patients with atrial fibrillation: a report from a European Observational Prospective AF Registry. Curr Probl Cardiol. 2023;48:101752.

Article  PubMed  Google Scholar 

Savelieva I, Fumagalli S, Kenny RA, Anker S, Benetos A, Boriani G, et al. EHRA expert consensus document on the management of arrhythmias in frailty syndrome, endorsed by the Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Latin America Heart Rhythm Society (LAHRS), and Cardiac Arrhythmia Society of Southern Africa (CASSA). Europace. 2023;25:1249.

Article  PubMed  PubMed Central  Google Scholar 

Proietti M, Marzona I, Vannini T, Tettamanti M, Fortino I, Merlino L, et al. Long-term relationship between atrial fibrillation, multimorbidity and oral anticoagulant drug use. Mayo Clin Proc. 2019;94:2427–36.

Article  CAS  PubMed  Google Scholar 

Chao TF, Liu CJ, Wang KL, Lin YJ, Chang SL, Lo LW, et al. Should atrial fibrillation patients with 1 additional risk factor of the CHA2DS2-VASc score (beyond sex) receive oral anticoagulation? J Am Coll Cardiol. 2015;65:635–42.

Article  PubMed  Google Scholar 

Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people. Lancet. 2014;383:1899–911.

Article  PubMed  PubMed Central  Google Scholar 

Yamada T, Kimura-Koyanagi M, Sakaguchi K, Ogawa W, Tamori Y. Obesity and risk for its comorbidities diabetes, hypertension, and dyslipidemia in Japanese individuals aged 65 years. Sci Rep. 2023;13:1–10.

Article  Google Scholar 

Al-Goblan AS, Al-Alfi MA, Khan MZ. Mechanism linking diabetes mellitus and obesity. Diabetes Metab Syndr Obes. 2014;7:587.

Article  PubMed  PubMed Central  Google Scholar 

Potpara TS, Lip GYH, Blomstrom-Lundqvist C, Boriani G, Van Gelder IC, Heidbuchel H, et al. The 4S-AF scheme (stroke risk; symptoms; severity of burden; substrate): a novel approach to in-depth characterization (rather than classification) of atrial fibrillation. Thromb Haemost. 2021;121:270–8.

Article  PubMed  Google Scholar 

Chao TF, Joung B, Takahashi Y, Lim TW, Choi EK, Chan YH, et al. 2021 Focused Update Consensus Guidelines of the Asia Pacific Heart Rhythm Society on Stroke Prevention in Atrial Fibrillation: Executive Summary. Thromb Haemost. 2021;122:20–47.

PubMed  PubMed Central  Google Scholar 

Buck J, Fromings Hill J, Martin A, Springate C, Ghosh B, Ashton R, et al. Reasons for discontinuing oral anticoagulation therapy for atrial fibrillation: a systematic review. Age Ageing. 2021;50:1108–17.

Article  PubMed  PubMed Central  Google Scholar 

Steinberg BA, Holmes DN, Ezekowitz MD, Fonarow GC, Kowey PR, Mahaffey KW, et al. Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. Am Heart J. 2013;165:622.

Article  PubMed  PubMed Central  Google Scholar 

Rillig A, Borof K, Breithardt G, Camm AJ, Crijns HJGM, Goette A, et al. Early rhythm control in patients with atrial fibrillation and high comorbidity burden. Circulation. 2022;146:836–47.

Article  PubMed  Google Scholar 

Gorog DA, Gue YX, Chao TF, Fauchier L, Ferreiro JL, Huber K, et al. Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: Executive Summary of a European and Asia-Pacific Expert Consensus Paper. Thromb Haemost. 2022;122:1625–52.

Article  PubMed  Google Scholar 

Proietti M, Vitolo M, Harrison SL, Lane DA, Fauchier L, Marin F, et al. Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry. BMC Med. 2021;19:256.

Article  PubMed  PubMed Central  Google Scholar 

Romiti GF, Proietti M, Corica B, Bonini N, Boriani G, Huisman MV, et al. Implications of clinical risk phenotypes on the management and natural history of atrial fibrillation: a report from the GLORIA-AF. J Am Heart Assoc. 2023;12:e030565.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vitolo M, Proietti M, Shantsila A, Boriani G, Lip GYH. Clinical phenotype classification of atrial fibrillation patients using cluster analysis and associations with trial-adjudicated outcomes. Biomedicines. 2021;9:843.

Article  PubMed  PubMed Central  Google Scholar 

Hindricks G, Potpara T, Dagres N, Bax JJ, Boriani G, Dan GA, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2021;42:373–498.

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