Sarcopenic obesity is part of obesity paradox in dementia development: evidence from a population-based cohort study

GBD 2019 Dementia Forecasting Collaborators. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health. 2022;7:e105–25.

Article  Google Scholar 

World Health Organization. Global status report on the public health response to dementia. 2021.

Google Scholar 

The Lancet Neurology. Increasing diversity in dementia research. Lancet Neurol. 2023;22:1.

Article  CAS  PubMed  Google Scholar 

Griffin P, Apostolova L, Dickerson BC, Rabinovici G, Salloway S, Brandt K, et al. Developments in understanding early onset Alzheimer’s disease. Alzheimers Dement J Alzheimers Assoc. 2023;19(9):S126–31.

Google Scholar 

GBD 2019 Demographics Collaborators. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019. Lancet Lond Engl. 2020;396:1160–203.

Article  Google Scholar 

Brookmeyer R, Gray S, Kawas C. Projections of Alzheimer’s disease in the United States and the public health impact of delaying disease onset. Am J Public Health. 1998;88:1337–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bowman K, Thambisetty M, Kuchel GA, Ferrucci L, Melzer D. Obesity and longer term risks of dementia in 65-74 year olds. Age Ageing. 2019;48:367–73.

Article  PubMed  PubMed Central  Google Scholar 

Lin A, Wang T, Li C, Pu F, Abdelrahman Z, Jin M, et al. Association of sarcopenia with cognitive function and dementia risk score: a national prospective cohort study. Metabolites. 2023;13:245.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tian S, Xu Y. Association of sarcopenic obesity with the risk of all-cause mortality: a meta-analysis of prospective cohort studies. Geriatr Gerontol Int. 2016;16:155–66.

Article  PubMed  Google Scholar 

Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, et al. Sarcopenic obesity is associated with cognitive impairment in community-dwelling older adults: The Bunkyo Health Study. Clin Nutr Edinb Scotl. 2022;41:1046–51.

Article  Google Scholar 

Batsis JA, Haudenschild C, Roth RM, Gooding TL, Roderka MN, Masterson T, et al. Incident impaired cognitive function in sarcopenic obesity: data from the National Health and Aging Trends Survey. J Am Med Dir Assoc. 2021;22:865–872.e5.

Article  PubMed  Google Scholar 

Murdock DJ, Wu N, Grimsby JS, Calle RA, Donahue S, Glass DJ, et al. The prevalence of low muscle mass associated with obesity in the USA. Skelet Muscle. 2022;12:26.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fernández-Andújar M, Morales-García E, García-Casares N. Obesity and gray matter volume assessed by neuroimaging: a systematic review. Brain Sci. 2021;11:999.

Article  PubMed  PubMed Central  Google Scholar 

Lampe L, Zhang R, Beyer F, Huhn S, Kharabian Masouleh S, Preusser S, et al. Visceral obesity relates to deep white matter hyperintensities via inflammation. Ann Neurol. 2019;85:194–203.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Evans K, Abdelhafiz D, Abdelhafiz AH. Sarcopenic obesity as a determinant of cardiovascular disease risk in older people: a systematic review. Postgrad Med. 2021;133:831–42.

Article  PubMed  Google Scholar 

Samieri C, Perier M-C, Gaye B, Proust-Lima C, Helmer C, Dartigues J-F, et al. Association of cardiovascular health level in older age with cognitive decline and incident dementia. JAMA. 2018;320:657–64.

Article  PubMed  PubMed Central  Google Scholar 

Altankhuyag I, Byambaa A, Tuvshinjargal A, Bayarmunkh A, Jadamba T, Dagvajantsan B, et al. Association between hand-grip strength and risk of stroke among Mongolian adults: results from a population-based study. Neurosci Res Notes. 2021;4:8–16.

Article  Google Scholar 

Sabia S, Fayosse A, Dumurgier J, Schnitzler A, Empana J-P, Ebmeier KP, et al. Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study. BMJ. 2019;366:l4414.

Article  PubMed  PubMed Central  Google Scholar 

Barbiellini Amidei C, Fayosse A, Dumurgier J, Machado-Fragua MD, Tabak AG, van Sloten T, et al. Association between age at diabetes onset and subsequent risk of dementia. JAMA. 2021;325:1640–9.

Article  PubMed  PubMed Central  Google Scholar 

Khadra D, Itani L, Tannir H, Kreidieh D, El Masri D, El Ghoch M. Association between sarcopenic obesity and higher risk of type 2 diabetes in adults: a systematic review and meta-analysis. World J Diabetes. 2019;10:311–23.

Article  PubMed  PubMed Central  Google Scholar 

Pilati I, Slee A, Frost R. Sarcopenic obesity and depression: a systematic review. J Frailty Aging. 2022;11:51–8.

CAS  PubMed  Google Scholar 

Elser H, Horváth-Puhó E, Gradus JL, Smith ML, Lash TL, Glymour MM, et al. Association of early-, middle-, and late-life depression with incident dementia in a Danish cohort. JAMA Neurol. 2023; https://doi.org/10.1001/jamaneurol.2023.2309.

Patel S, Wei J, Shi Z, Rifkin AS, Zheng SL, Gelfman E, et al. Refining risk for Alzheimer’s disease among heterozygous APOEɛ4 carriers. J Alzheimers Dis JAD. 2023;94:483–9.

Article  CAS  PubMed  Google Scholar 

Palmer LJ. UK Biobank: bank on it. Lancet Lond Engl. 2007;369:1980–2.

Article  Google Scholar 

Sudlow C, Gallacher J, Allen N, Beral V, Burton P, Danesh J, et al. UK Biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med. 2015;12:e1001779.

Article  PubMed  PubMed Central  Google Scholar 

World Health Organization. Measuring change in nutritional status: guidelines for assessing the nutritional impact of supplementary feeding programmes for vulnerable groups. World Health Organization; 1983.

Google Scholar 

Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48:601.

Article  PubMed  PubMed Central  Google Scholar 

Janssen I, Heymsfield SB, Baumgartner RN, Ross R. Estimation of skeletal muscle mass by bioelectrical impedance analysis. J Appl Physiol Bethesda Md. 1985;2000(89):465–71.

Google Scholar 

Bassett DR. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003;35:1396.

Article  PubMed  Google Scholar 

Thompson DJ, Wells D, Selzam S, Peneva I, Moore R, Sharp K, et al. UK Biobank release and systematic evaluation of optimised polygenic risk scores for 53 diseases and quantitative traits. MedRxiv. 2022;16:2022–06. https://doi.org/10.1101/2022.06.16.22276246.

Article  Google Scholar 

Buuren S van, Groothuis-Oudshoorn K. mice: multivariate imputation by chained equations in R. J Stat Softw 2011;45:1–67.

Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, et al. Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2. Nat Metab. 2021;3:1552–68.

Article  CAS  PubMed  Google Scholar 

Hong S-H, Choi KM. Sarcopenic obesity, insulin resistance, and their implications in cardiovascular and metabolic consequences. Int J Mol Sci. 2020;21:494.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94:496–509.

Article  Google Scholar 

Uno H, Claggett B, Tian L, Inoue E, Gallo P, Miyata T, et al. Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. J Clin Oncol Off J Am Soc Clin Oncol. 2014;32:2380–5.

Article  Google Scholar 

Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986;51:1173–82.

Article  CAS  PubMed  Google Scholar 

Guo D, Zhang X, Zhan C, Lin Q, Liu J, Yang Q, et al. Sex differences in the association between obesity and cognitive impairment in a low-income elderly population in rural China: a population-based cross-sectional study. Front Neurol. 2021;12:669174.

Article  PubMed  PubMed Central  Google Scholar 

Hu Y, Xia C, Chen H, Song W, Zhou Q, Yang X, et al. Sex differences in the association between different obesity parameters and cognitive function in older adults: a cross-sectional study in rural China. Gerontology. 2022;68:799–807.

Article  CAS  PubMed  Google Scholar 

Dahl AK, Löppönen M, Isoaho R, Berg S, Kivelä S-L. Overweight and obesity in old age are not associated with greater dementia risk. J Am Geriatr Soc. 2008;56:2261–6.

Article  PubMed  Google Scholar 

Neergaard JS, Dragsbæk K, Hansen HB, Henriksen K, Christiansen C, Karsdal MA. Late-life risk factors for all-cause dementia and differential dementia diagnoses in women: a prospective cohort study. Medicine (Baltimore). 2016;95:e3112.

Article  CAS  PubMed  Google Scholar 

Power BD, Alfonso H, Flicker L, Hankey GJ, Yeap BB, Almeida OP. Body adiposity in later life and the incidence of dementia: the health in men study. PLoS One. 2011;6:e17902.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beeri MS, Leugrans SE, Delbono O, Bennett DA, Buchman AS. Sarcopenia is associated with incident Alzheimer’s dementia, mild cognitive impairment, and cognitive d

留言 (0)

沒有登入
gif