Report on the nutrition and chronic diseases status of chinese residents 2020 (in Chinese). Acta Nutrimenta Sinica. 2020;42:521
Liu Y, Ding Z. Obesity, a serious etiologic factor for male subfertility in modern society. Reproduction. 2017;154:R123–31.
Ma JX, Wang B, Li HS, Jiang XJ, Yu J, Ding CF, et al. Association between obesity-associated markers and semen quality parameters and serum reproductive hormones in Chinese infertile men. Reprod Biol Endocrinol. 2020;18:95.
Article CAS PubMed PubMed Central Google Scholar
Ferigolo PC, de Ribeiro Andrade MB, Camargo M, Carvalho VM, Cardozo KHM, Bertolla RP, et al. Sperm functional aspects and enriched proteomic pathways of seminal plasma of adult men with obesity. Andrology. 2019;7:341–9.
Article CAS PubMed Google Scholar
Pitman JL, Wheeler MC, Lloyd DJ, Walker JR, Glynne RJ, Gekakis N. A gain-of-function mutation in adenylate cyclase 3 protects mice from diet-induced obesity. PLoS One. 2014;9:e110226.
Article ADS PubMed PubMed Central Google Scholar
Stergiakouli E, Gaillard R, Tavare JM, Balthasar N, Loos RJ, Taal HR, et al. Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. Obesity (Silver Spring). 2014;22:2252–9.
Article CAS PubMed Google Scholar
Jansen V, Alvarez L, Balbach M, Strunker T, Hegemann P, Kaupp UB, et al. Controlling fertilization and cAMP signaling in sperm by optogenetics. Elife. 2015;4:e05161.
Article PubMed PubMed Central Google Scholar
Boisen IM, Rehfeld A, Mos I, Poulsen NN, Nielsen JE, Schwarz P, et al. The calcium-sensing receptor is essential for calcium and bicarbonate sensitivity in human spermatozoa. J Clin Endocrinol Metab. 2021;106:e1775–92.
Li Z, Liang Y, Xia N, Lai Y, Pan H, Zhou S, et al. Liraglutide reduces body weight by upregulation of adenylate cyclase 3. Nutr Diabetes. 2017;7:e265.
Article CAS PubMed PubMed Central Google Scholar
Liang Y, Li Z, Liang S, Li Y, Yang L, Lu M, et al. Hepatic adenylate cyclase 3 is upregulated by Liraglutide and subsequently plays a protective role in insulin resistance and obesity. Nutr Diabetes. 2016;6:e191.
Article CAS PubMed PubMed Central Google Scholar
Li Z, Yang P, Liang Y, Xia N, Li Y, Su H, et al. Effects of liraglutide on lipolysis and the AC3/PKA/HSL pathway. Diabetes Metab Syndr Obes. 2019;12:1697–703.
Article CAS PubMed PubMed Central Google Scholar
Landry D, Cloutier F, Martin LJ. Implications of leptin in neuroendocrine regulation of male reproduction. Reprod Biol. 2013;13:1–14.
Galliano D, Bellver J. Female obesity: short- and long-term consequences on the offspring. Gynecol Endocrinol. 2013;29:626–31.
Binder NK, Sheedy JR, Hannan NJ, Gardner DK. Male obesity is associated with changed spermatozoa Cox4i1 mRNA level and altered seminal vesicle fluid composition in a mouse model. Mol Hum Reprod. 2015;21:424–34.
Article CAS PubMed Google Scholar
Burmeister MA, Ayala JE, Smouse H, Landivar-Rocha A, Brown JD, Drucker DJ, et al. The hypothalamic glucagon-like peptide 1 receptor is sufficient but not necessary for the regulation of energy balance and glucose homeostasis in mice. Diabetes. 2017;66:372–84.
Article CAS PubMed Google Scholar
Drucker DJ. Mechanisms of action and therapeutic application of glucagon-like peptide-1. Cell Metab. 2018;27:740–56.
Article CAS PubMed Google Scholar
Dai C, Zhu W. Effects of GLP-1 receptor agonists on asprosin levels in normal weight or overweight/obesity patients with type 2 diabetes mellitus. Medicine. 2022;101:e31334.
Article CAS PubMed PubMed Central Google Scholar
Huang YJ, Guo WC, Jv MX, Wang JJ, Yi SX, Fang PH, et al. Effect of liraglutide on hepatic lipid metabolism in high-fat induced obese mice(in Chinese). Chin J Diabetes Mellitus. 2022;14(7):704–710.
Reis LO, Dias FG. Male fertility, obesity, and bariatric surgery. Reprod Sci. 2012;19:778–85.
Mintziori G, Nigdelis MP, Mathew H, Mousiolis A, Goulis DG, Mantzoros CS. The effect of excess body fat on female and male reproduction. Metabolism. 2020;107:154193.
Article CAS PubMed Google Scholar
Craig JR, Jenkins TG, Carrell DT, Hotaling JM. Obesity, male infertility, and the sperm epigenome. Fertil Steril. 2017;107:848–59.
Simo R, Saez-Lopez C, Barbosa-Desongles A, Hernandez C, Selva DM. Novel insights in SHBG regulation and clinical implications. Trends Endocrinol Metab. 2015;26:376–83.
Article CAS PubMed Google Scholar
Gao SS, Zhang AM, Yang H, Zhuo RY. Research of the relationship between sex hormone binding globulin and glycolipid metabolism in patients with obese polycystic ovary syndrome (in Chinese). Chin J Prim Med Pharm. 2020;27:2311–4.
Wei S, Schmidt MD, Dwyer T, Norman RJ, Venn AJ. Obesity and menstrual irregularity: associations with SHBG, testosterone, and insulin. Obesity (Silver Spring). 2009;17:1070–6.
Article CAS PubMed Google Scholar
Silfen ME, Denburg MR, Manibo AM, Lobo RA, Jaffe R, Ferin M, et al. Early endocrine, metabolic, and sonographic characteristics of polycystic ovary syndrome (PCOS): comparison between nonobese and obese adolescents. J Clin Endocrinol Metab. 2003;88:4682–8.
Article CAS PubMed Google Scholar
Qu X, Donnelly R. Sex Hormone-Binding Globulin (SHBG) as an early biomarker and therapeutic target in polycystic ovary syndrome. Int J Mol Sci. 2020;21:8191.
Article CAS PubMed PubMed Central Google Scholar
Izzi-Engbeaya C, Jones S, Crustna Y, Machenahalli P, Papadopoulou D, Modi M, et al. SUN-LB044 Effects of Glucagon-Like Peptide-1 (GLP-1) on the hypothalamic-pituitary-gonadal axis in healthy men. J Endocr Soc. 2019;3:SUN-LB044.
Article PubMed Central Google Scholar
George JT, Veldhuis JD, Tena-Sempere M, Millar RP, Anderson RA. Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism. Clin Endocrinol (Oxf). 2013;79:100–4.
Article CAS PubMed Google Scholar
Beak SA, Heath MM, Small CJ, Morgan DG, Ghatei MA, Taylor AD, et al. Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line. J Clin Invest. 1998;101:1334–41.
Article CAS PubMed PubMed Central Google Scholar
Caltabiano R, Condorelli D, Panza S, Boitani C, Musso N, Ježek D, et al. Glucagon-like peptide-1 receptor is expressed in human and rodent testis. Andrology. 2020;8:1935–45.
Article CAS PubMed Google Scholar
Cannarella R, Calogero AE, Condorelli RA, Greco EA, Aversa A, La Vignera S. Is there a role for glucagon-like peptide-1 receptor agonists in the treatment of male infertility? Andrology. 2021;9:1499–503.
Article CAS PubMed PubMed Central Google Scholar
Holst JJ, Gromada J. Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab. 2004;287:E199–206.
Article CAS PubMed Google Scholar
Doyle ME, Egan JM. Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacol Ther. 2007;113:546–93.
Article CAS PubMed Google Scholar
Ostrom KF, LaVigne JE, Brust TF, Seifert R, Dessauer CW, Watts VJ, et al. Physiological roles of mammalian transmembrane adenylyl cyclase isoforms. Physiol Rev. 2022;102:815–57.
Article CAS PubMed Google Scholar
Wong ST, Trinh K, Hacker B, Chan GC, Lowe G, Gaggar A, et al. Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice. Neuron. 2000;27:487–97.
Article CAS PubMed Google Scholar
Zhou YF, Wang WN, Yuan HN, Yuan HN, Zhang MD, Wu XB, Wang YW, et al. The expression of olfactory receptors and related genes is decreased in mice with deletion of adenylyl cyclase 3 (in Chinese). Chin J Biochem Mol Biol. 2017;33(11):1143–51.
Boehm N, Aron C. Inhibitory effects of centrally and peripherally induced anosmia on mounting behavior in the female rat. Physiol Behav. 1990;48:367–70.
Article CAS PubMed Google Scholar
Gautier-Courteille C, Salanova M, Conti M. The olfactory adenylyl cyclase III is expressed in rat germ cells during spermiogenesis. Endocrinology. 1998;139:2588–99.
留言 (0)