Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72:7–33.
McIntyre A, Ganti AK. Lung cancer—a global perspective. J Surg Oncol. 2017;115:550–4.
Cao M, Chen W. Epidemiology of lung cancer in China. Thorac Cancer. 2019;10:3–7.
Singal G, Miller PG, Agarwala V, Li G, Kaushik G, Backenroth D, et al. Association of Patient characteristics and tumor genomics with clinical outcomes among patients with non-small cell lung cancer using a clinicogenomic database. J Am Med Assoc. 2019;321:1391–9.
Ettinger DS, Wood DE, Aisner DL, Akerley W, Bauman JR, Bharat A, et al. Non-small cell lung cancer, version 3.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2022;20:497–530.
Hanna NH, Robinson AG, Temin S, Baker S Jr, Brahmer JR, Ellis PM, et al. Therapy for stage IV non-small-cell lung cancer with driver alterations: ASCO and OH (CCO) Joint Guideline Update. J Clin Oncol. 2021;39:1040–91.
Article CAS PubMed Google Scholar
Nguyen CDK, Yi C. YAP/TAZ signaling and resistance to cancer therapy. Trends Cancer. 2019;5:283–96.
Article CAS PubMed PubMed Central Google Scholar
Ma S, Meng Z, Chen R, Guan KL. The Hippo pathway: biology and pathophysiology. Annu Rev Biochem. 2019;88:577–604.
Article CAS PubMed Google Scholar
Wang M, Dai M, Wang D, Xiong W, Zeng Z, Guo C. The regulatory networks of the Hippo signaling pathway in cancer development. J Cancer. 2021;12:6216–30.
Article CAS PubMed PubMed Central Google Scholar
Yu FX, Zhao B, Guan KL. Hippo pathway in organ size control, tissue homeostasis, and cancer. Cell. 2015;163:811–28.
Article CAS PubMed PubMed Central Google Scholar
Meng Z, Moroishi T, Guan KL. Mechanisms of Hippo pathway regulation. Genes Dev. 2016;30:1–17.
Article CAS PubMed PubMed Central Google Scholar
Rausch V, Hansen CG. The Hippo pathway, YAP/TAZ, and the plasma membrane. Trends Cell Biol. 2020;30:32–48.
Article CAS PubMed Google Scholar
Dupont S. Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction. Exp Cell Res. 2016;343:42–53.
Article CAS PubMed Google Scholar
Mohri Z, Del Rio Hernandez A, Krams R. The emerging role of YAP/TAZ in mechanotransduction. J Thorac Dis. 2017;9:E507–9.
Article PubMed PubMed Central Google Scholar
Park J, Hansen CG. Cellular feedback dynamics and multilevel regulation driven by the hippo pathway. Biochem Soc Trans. 2021;49:1515–27.
Article CAS PubMed PubMed Central Google Scholar
Hergovich A, Hemmings BA. Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling. Biofactors. 2009;35:338–45.
Article CAS PubMed Google Scholar
Moroishi T, Hansen CG, Guan KL. The emerging roles of YAP and TAZ in cancer. Nat Rev Cancer. 2015;15:73–9.
Article CAS PubMed PubMed Central Google Scholar
Wang S, Zhou L, Ling L, Meng X, Chu F, Zhang S, et al. The crosstalk between Hippo-YAP Pathway and innate immunity. Front Immunol. 2020;11:323.
Article PubMed PubMed Central Google Scholar
Johnson R, Halder G. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nat Rev Drug Discov. 2014;13:63–79.
Article CAS PubMed Google Scholar
Song Y, Fu J, Zhou M, Xiao L, Feng X, Chen H, et al. Activated Hippo/Yes-associated protein pathway promotes cell proliferation and anti-apoptosis in endometrial stromal cells of endometriosis. J Clin Endocrinol Metab. 2016;101:1552–61.
Article CAS PubMed PubMed Central Google Scholar
Varelas X. The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease. Development. 2014;141:1614–26.
Article CAS PubMed Google Scholar
Davis JR, Tapon N. Hippo signalling during development. Development 2019;146:dev167106.
Pan D. The hippo signaling pathway in development and cancer. Dev Cell. 2010;19:491–505.
Article CAS PubMed PubMed Central Google Scholar
Liu-Chittenden Y, Huang B, Shim JS, Chen Q, Lee SJ, Anders RA, et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev. 2012;26:1300–5.
Article CAS PubMed PubMed Central Google Scholar
Zanconato F, Cordenonsi M, Piccolo S. YAP/TAZ at the roots of cancer. Cancer Cell. 2016;29:783–803.
Article CAS PubMed PubMed Central Google Scholar
Wang Y, Xu X, Maglic D, Dill MT, Mojumdar K, Ng PK, et al. Comprehensive molecular characterization of the Hippo signaling pathway in cancer. Cell Rep. 2018;25:1304–17.e1305.
Article CAS PubMed PubMed Central Google Scholar
Huo X, Zhang Q, Liu AM, Tang C, Gong Y, Bian J, et al. Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma. Oncol Rep. 2013;29:840–6.
Article CAS PubMed Google Scholar
Chen J, Zhang K, Zhi Y, Wu Y, Chen B, Bai J, et al. Tumor-derived exosomal miR-19b-3p facilitates M2 macrophage polarization and exosomal LINC00273 secretion to promote lung adenocarcinoma metastasis via Hippo pathway. Clin Transl Med. 2021;11:e478.
Article CAS PubMed PubMed Central Google Scholar
Liu Y, Song Y, Cao M, Fan W, Cui Y, Cui Y, et al. A novel EHD1/CD44/Hippo/SP1 positive feedback loop potentiates stemness and metastasis in lung adenocarcinoma. Clin Transl Med. 2022;12:e836.
Article CAS PubMed PubMed Central Google Scholar
Ma S, Wu Z, Yang F, Zhang J, Johnson RL, Rosenfeld MG, et al. Hippo signalling maintains ER expression and ER(+) breast cancer growth. Nature. 2021;591:E1–10.
Article ADS CAS PubMed PubMed Central Google Scholar
Dai Y, Liu S, Zhang WQ, Yang YL, Hang P, Wang H, et al. YAP1 regulates ABCG2 and cancer cell side population in human lung cancer cells. Oncotarget. 2017;8:4096–109.
Zhang Y, Yan S, Chen J, Gan C, Chen D, Li Y, et al. WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma. J Cell Mol Med. 2017;21:3718–29.
Article CAS PubMed PubMed Central Google Scholar
Zhang WQ, Dai YY, Hsu PC, Wang H, Cheng L, Yang YL, et al. Targeting YAP in malignant pleural mesothelioma. J Cell Mol Med. 2017;21:2663–76.
Article CAS PubMed PubMed Central Google Scholar
Xia J, Zeng M, Zhu H, Chen X, Weng Z, Li S. Emerging role of Hippo signalling pathway in bladder cancer. J Cell Mol Med. 2018;22:4–15.
Kulkarni A, Chang MT, Vissers JHA, Dey A, Harvey KF. The Hippo pathway as a driver of select human cancers. Trends Cancer. 2020;6:781–96.
Article CAS PubMed Google Scholar
Chen L, Feng P, Peng A, Qiu X, Zhu X, He S, et al. cAMP response element-binding protein and Yes-associated protein form a feedback loop that promotes neurite outgrowth. J Cell Mol Med. 2018;22:374–81.
Article CAS PubMed Google Scholar
Shao DD, Xue W, Krall EB, Bhutkar A, Piccioni F, Wang X, et al. KRAS and YAP1 converge to regulate EMT and tumor survival. Cell. 2014;158:171–84.
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