Abadi M, et al. TensorFlow: large-scale machine learning on heterogeneous systems. In: Proceedings of the 12th USENIX conference on Operating Systems Design and Implementation. USENIX Association. 2016. pp. 265–83. http://tensorflow.org/. Accessed 13 Aug 2016.

Abdalla A, Atcherley CW, Pathirathna P, Samaranayake S, Qiang B, Peña E, Morgan SL, Heien ML, Hashemi P. In vivo ambient serotonin measurements at carbon-fiber microelectrodes. Anal Chem. 2017;89:9703–11.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Agid Y. Parkinson’s disease: pathophysiology. The Lancet. 1991;337:1321–4.

Article  CAS  Google Scholar 

Albin RL, Koeppe RA, Bohnen NI, Wernette K, Kilbourn MA, Frey KA. Spared caudal brainstem SERT binding in early Parkinson’s disease. J Cereb Blood Flow Metab. 2008;28:441–4.

Article  CAS  PubMed  Google Scholar 

Alex KD, Pehek E. Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacol Ther. 2007;113:296–320.

Article  CAS  PubMed  Google Scholar 

Atcherley CW, Laude ND, Parent KL, Heien ML. Fast-scan controlled-adsorption voltammetry for the quantification of absolute concentrations and adsorption dynamics. Langmuir. 2013;29:14885–92.

Article  CAS  PubMed  Google Scholar 

Atcherley CW, Wood KM, Parent KL, Hashemi P, Heien ML. The coaction of tonic and phasic dopamine dynamics. Chem Commun. 2015;51:2235–8.

Article  CAS  Google Scholar 

Bang D, Kishida KT, Lohrenz T, White JP, Laxton AW, Tatter SB, Fleming SM, Montague PR. Sub-second dopamine and serotonin signaling in human striatum during perceptual decision-making. Neuron. 2020;108:999-1010.e6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bergstrom BP, Garris PA. ‘Passive stabilization’of striatal extracellular dopamine across the lesion spectrum encompassing the presymptomatic phase of Parkinson’s disease: a voltammetric study in the 6-OHDA-lesioned rat. J Neurochem. 2003;87:1224–36.

Article  CAS  PubMed  Google Scholar 

Boska MD, Hasan KM, Kibuule D, Banerjee R, McIntyre E, Nelson JA, Hahn T, Gendelman HE, Mosley RL. Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson’s disease. Neurobiol Dis. 2007;26:590–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bouchez G, Sensebé L, Vourc’h P, Garreau L, Bodard S, Rico A, Guilloteau D, Charbord P, Besnard JC, Chalon S. Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson’s disease. Neurochem Int. 2008;52:1332–42.

Article  CAS  PubMed  Google Scholar 

Bové J, Prou D, Perier C, Przedborski S. Toxin-induced models of Parkinson’s disease. NeuroRx. 2005;2:484–94.

Article  PubMed  PubMed Central  Google Scholar 

Brooks DJ. Imaging non-dopaminergic function in Parkinson’s disease. Mol Imaging Biol. 2007;9:217–22.

Article  PubMed  Google Scholar 

Brooks DJ, Pavese N. Imaging biomarkers in Parkinson’s disease. Prog Neurobiol. 2011;95:614–28.

Article  CAS  PubMed  Google Scholar 

Bundgaard C, Jørgensen M, Larsen F. Pharmacokinetic modelling of blood-brain barrier transport of escitalopram in rats. Biopharm Drug Dispos. 2007;28:349–60.

Article  CAS  PubMed  Google Scholar 

Burrell MH, Atcherley CW, Heien ML, Lipski J. A novel electrochemical approach for prolonged measurement of absolute levels of extracellular dopamine in brain slices. ACS Chem Neurosci. 2015;6:1802–12.

Article  CAS  PubMed  Google Scholar 

Cachope R, Cheer JF. Local control of striatal dopamine release. Front Behav Neurosci. 2014. https://doi.org/10.3389/fnbeh.2014.00188.

Article  PubMed  PubMed Central  Google Scholar 

Carr GV, Lucki I. Chapter 4.2-The role of serotonin in depression. In: Müller CP, Jacobs BL, editors. Handbook of behavioral neuroscience. Amsterdam: Elsevier; 2010. p. 493–505.

Google Scholar 

Carta M, Björklund A. The serotonergic system in L-DOPA-induced dyskinesia: pre-clinical evidence and clinical perspective. J Neural Transm. 2018;125:1195–202.

Article  CAS  PubMed  Google Scholar 

Carta M, Tronci E. Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations. Front Neurol. 2014. https://doi.org/10.3389/fneur.2014.00078.

Article  PubMed  PubMed Central  Google Scholar 

Castagnola E, Thongpang S, Hirabayashi M, Nava G, Nimbalkar S, Nguyen T, Lara S, Oyawale A, Bunnell J, Moritz C, Kassegne S. Glassy carbon microelectrode arrays enable voltage-peak separated simultaneous detection of dopamine and serotonin using fast scan cyclic voltammetry. Analyst. 2021;146:3955–70.

Article  ADS  CAS  PubMed  Google Scholar 

Ceravolo R, Nuti A, Piccinni A, Agnello GD, Bellini G, Gambaccini G, Osso LD, Murri L, Bonuccelli U. Paroxetine in Parkinson’s disease: Effects on motor and depressive symptoms. Neurology. 2000;55:1216.

Article  CAS  PubMed  Google Scholar 

Choi C, Sohn YH, Lee JH, Kim J-S. The effect of long-term levodopa therapy on depression level in de novo patients with Parkinson’s disease. J Neurol Sci. 2000;172:12–6.

Article  CAS  PubMed  Google Scholar 

Conti Mazza MM, Centner A, Werner DF, Bishop C. Striatal serotonin transporter gain-of-function in L-DOPA-treated, hemi-parkinsonian rats. Brain Res. 2023;1811:148381.

Article  CAS  PubMed  Google Scholar 

Coppen AJ, Doogan DP. Serotonin and its place in the pathogenesis of depression. J Clin Psychiatry. 1988;49(Suppl):4–11.

PubMed  Google Scholar 

Corsi S, Stancampiano R, Carta M. Serotonin/dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesia: an update. Prog Brain Res. 2021;261:287–302.

Article  PubMed  Google Scholar 

Cummings JL. Depression and Parkinson’s disease: a review. Am J Psychiatry. 1992. https://doi.org/10.1176/ajp.149.4.443.

Article  PubMed  Google Scholar 

Dale E, Pehrson AL, Jeyarajah T, Li Y, Leiser SC, Smagin G, Olsen CK, Sanchez C. Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function. CNS Spectr. 2016;21:143–61.

Article  PubMed  Google Scholar 

Dell’Agnello G, Ceravolo R, Nuti A, Bellini G, Piccinni A, D’Avino C, Dell’Osso L, Bonuccelli U. SSRIs do not worsen Parkinson’s disease: evidence from an open-label, prospective study. Clin Neuropharmacol. 2001. https://doi.org/10.1097/00002826-200107000-00005.

Article  PubMed  Google Scholar 

Devos D, Dujardin K, Poirot I, Moreau C, Cottencin O, Thomas P, Destée A, Bordet R, Defebvre L. Comparison of desipramine and citalopram treatments for depression in Parkinson’s disease: a double-blind, randomized, placebo-controlled study. Mov Disord. 2008;23:850–7.

Article  PubMed  Google Scholar 

Di Giovanni G, Esposito E, Di Matteo V. In vivo microdialysis in parkinson’s research. In: Giovanni G, Di Matteo V, Esposito E, editors. Birth, life and death of dopaminergic neurons in the substantia nigra. Vienna: Springer; 2009. p. 223–43. https://doi.org/10.1007/978-3-211-92660-4_1.

Chapter  Google Scholar 

Ding B, Qian H, Zhou J. Activation functions and their characteristics in deep neural networks. In: Proceedings of the 30th Chinese Control and Decision Conference, CCDC 2018. Institute of Electrical and Electronics Engineers Inc. 2018. pp. 1836–41

Drevets WC, Frank E, Price JC, Kupfer DJ, Holt D, Greer PJ, Huang Y, Gautier C, Mathis C. PET imaging of serotonin 1A receptor binding in depression. Biol Psychiatry. 1999. https://doi.org/10.1016/S0006-3223(99)00189-4.

Article  PubMed  Google Scholar 

Fernagut P-O, Hutson CB, Fleming SM, Tetreaut NA, Salcedo J, Masliah E, Chesselet M. Behavioral and histopathological consequences of paraquat intoxication in mice: effects of α-synuclein over-expression. Synapse. 2007;61:991–1001.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fidalgo C, Ko WKD, Tronci E, Li Q, Stancampiano R, Chuan Q, Bezard E, Carta M. Effect of serotonin transporter blockade on L-DOPA-induced dyskinesia in animal models of Parkinson’s disease. Neuroscience. 2015;298:389–96.

Article  CAS  PubMed  Google Scholar 

Fornai F, Schlüter OM, Lenzi P, Gesi M, Ruffoli R, Ferrucci M, Lazzeri G, Busceti CL, Pontarelli F, Battaglia G. Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and α-synuclein. Proc Natl Acad Sci. 2005;102:3413–8.

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Garris PA, Walker QD, Wightman RM. Dopamine release and uptake rates both decrease in the partially denervated striatum in proportion to the loss of dopamine terminals. Brain Res. 1997;753:225–34.

Article  CAS  PubMed  Google Scholar 

Gould TD, Dao DT, Kovacsics CE. The open field test. In: Gould TD, editor. Mood and anxiety related phenotypes in mice: characterization using behavioral tests. Totowa: Humana Press; 2009. p. 1–20.

Chapter  Google Scholar 

Greenamyre JT, Betarbet R, Sherer TB. The rotenone model of Parkinson’s disease: genes, environment and mitochondria. Parkinsonism Relat Disord. 2003;9:59–64.

Article