Emerging roles of the long non-coding RNA NEAT1 in gynecologic cancers

Adorno-Cruz V, Hoffmann AD, Liu X, Dashzeveg NK, Taftaf R, Wray B, Keri RA, Liu H (2021) ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis. Genes Dis 8:493–508

Article  CAS  PubMed  Google Scholar 

An J, Lv W, Zhang Y (2017) LncRNA NEAT1 contributes to paclitaxel resistance of ovarian cancer cells by regulating ZEB1 expression via miR-194. Onco Targets Ther 10:5377

Article  PubMed  PubMed Central  Google Scholar 

An H, Williams NG, Shelkovnikova TA (2018) NEAT1 and paraspeckles in neurodegenerative diseases: a missing lnc found? Non-Coding RNA Res 3:243–252

Article  CAS  Google Scholar 

Balihodzic A, Prinz F, Dengler MA, Calin GA, Jost PJ, Pichler M (2022) Non-coding RNAs and ferroptosis: potential implications for cancer therapy. Cell Death Differ 29(6):1–13

Article  Google Scholar 

Beg A, Parveen R, Fouad H, Yahia M, Hassanein AS (2022) Role of different non-coding RNAs as ovarian cancer biomarkers. J Ovarian Res 15:1–11

Article  Google Scholar 

Bolha L, Ravnik-Glavač M, Glavač D (2017) Long noncoding RNAs as biomarkers in cancer. Dis Markers. https://doi.org/10.1155/2017/7243968

Article  PubMed  PubMed Central  Google Scholar 

Bu FT, Wang A, Zhu Y, You HM, Zhang YF, Meng XM, Huang C, Li J (2020) LncRNA NEAT1: shedding light on mechanisms and opportunities in liver diseases. Liver Int 40:2612–2626

Article  CAS  PubMed  Google Scholar 

Butler AA, Johnston DR, Kaur S, Lubin FD (2019) Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment. Sci Signal 12:eaaw9277

Article  PubMed  PubMed Central  Google Scholar 

Chai Y, Liu J, Zhang Z, Liu L (2016) HuR-regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer. Cancer Med 5:1588–1598

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Z, Zhang Z, Xie B, Zhang H (2016) Clinical significance of up-regulated lncRNA NEAT1 in prognosis of ovarian cancer. Eur Rev Med Pharmacol Sci 20:3373–3377

PubMed  Google Scholar 

Chen T, Wang H, Yang P, He ZY (2017) Prognostic role of long noncoding RNA NEAT1 in various carcinomas: a meta-analysis. Onco Targets Ther 10:993–1000

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen DD, Hui LL, Zhang XC, Chang Q (2019) NEAT1 contributes to ox-LDL-induced inflammation and oxidative stress in macrophages through inhibiting miR-128. J Cell Biochem 120:2493–2501

Article  CAS  PubMed  Google Scholar 

Di Fiore R, Suleiman S, Ellul B, Otoole SA, Savona-Ventura C, Felix A, Napolioni V, Conlon NT, Kahramanoglu I, Azzopardi MJ (2021) Gynocare update: modern strategies to improve diagnosis and treatment of rare gynecologic tumors—current challenges and future directions. Cancers 13:493

Article  PubMed  PubMed Central  Google Scholar 

Dilmaghnai NA, Shoorei H, Sharifi G, Mohaqiq M, Majidpoor J, Dinger ME, Taheri M, Ghafouri-Fard S (2021) Non-coding RNAs modulate function of extracellular matrix proteins. Biomed Pharmacother 136:111240

Article  Google Scholar 

Ding N, Wu H, Tao T, Peng E (2017) NEAT1 regulates cell proliferation and apoptosis of ovarian cancer by miR-34a-5p/BCL2. Onco Targets Ther 10:4905–4915

Article  PubMed  PubMed Central  Google Scholar 

Dong P, Xiong Y, Yue J, Hanley SJ, Kobayashi N, Todo Y, Watari H (2018) Long non-coding RNA NEAT1: a novel target for diagnosis and therapy in human tumors. Front Genet 9:471

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong P, Xiong Y, Yue J, Xu D, Ihira K, Konno Y, Kobayashi N, Todo Y, Watari H (2019) Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes. J Exp Clin Cancer Res 38:1–15

Article  CAS  Google Scholar 

El-Fattah AAA, Sadik NAH, Shaker OG, Mohamed Kamal A, Shahin NN (2021) Serum long non-coding RNAs PVT1, HOTAIR, and NEAT1 as potential biomarkers in Egyptian women with breast cancer. Biomolecules 11:301

Article  PubMed  PubMed Central  Google Scholar 

Fan J-T, Zhou Z-Y, Luo Y-L, Luo Q, Chen S-B, Zhao J-C, Chen Q-R (2021) Exosomal lncRNA NEAT1 from cancer-associated fibroblasts facilitates endometrial cancer progression via miR-26a/b-5p-mediated STAT3/YKL-40 signaling pathway. Neoplasia 23:692–703

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fang Y, Fullwood MJ (2016) Roles, functions, and mechanisms of long non-coding RNAs in cancer. Genom Proteom Bioinform 14:42–54

Article  Google Scholar 

Gan L, Yang Y, Li Q, Feng Y, Liu T, Guo W (2018) Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential. Biomark Res 6:10

Article  PubMed  PubMed Central  Google Scholar 

Geng F, Jia W-C, Li T, Li N, Wei W (2022) Knockdown of lncRNA NEAT1 suppresses proliferation and migration, and induces apoptosis of cervical cancer cells by regulating the miR-377/FGFR1 axis. Mol Med Rep 25:1–11

CAS  Google Scholar 

Grammatikakis I, Lal A (2022) Significance of lncRNA abundance to function. Mamm Genome 33:271–280

Article  CAS  PubMed  Google Scholar 

Gu J, Zhang B, An R, Qian W, Han L, Duan W, Wang Z, Ma Q (2022) Molecular interactions of the long noncoding RNA NEAT1 in cancer. Cancers 14:4009

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guo H, Yang S, Zhao S, Li L, Yan M, Fan M (2018) LncRNA NEAT1 regulates cervical carcinoma proliferation and invasion by targeting AKT/PI3K. Eur Rev Med Pharmacol Sci 22:4090–4097

PubMed  Google Scholar 

Han D, Wang J, Cheng G (2018) LncRNA NEAT1 enhances the radio-resistance of cervical cancer via miR-193b-3p/CCND1 axis. Oncotarget 9:2395–2409

Article  PubMed  Google Scholar 

Hashemipour M, Boroumand H, Mollazadeh S, Tajiknia V, Nourollahzadeh Z, Borj MR, Pourghadamyari H, Rahimian N, Hamblin MR, Mirzaei H (2021) Exosomal microRNAs and exosomal long non-coding RNAs in gynecologic cancers. Gynecol Oncol 161:314–327

Article  CAS  PubMed  Google Scholar 

Huang X, Zhong R, He X, Deng Q, Peng X, Li J, Luo X (2019) Investigations on the mechanism of progesterone in inhibiting endometrial cancer cell cycle and viability via regulation of long noncoding RNA NEAT1/microRNA-146b-5p mediated Wnt/β-catenin signaling. IUBMB Life 71:223–234

Article  CAS  PubMed  Google Scholar 

Hussein NH, Eissa RA, de Bruyn M, El Tayebi HM (2022) NEAT1: culprit lncRNA linking PIG-C, MSLN, and CD80 in triple-negative breast cancer. Life Sci 299:120523

Article  CAS  PubMed  Google Scholar 

Jafari SH, Saadatpour Z, Salmaninejad A, Momeni F, Mokhtari M, Nahand JS, Rahmati M, Mirzaei H, Kianmehr M (2018) Breast cancer diagnosis: imaging techniques and biochemical markers. J Cell Physiol 233:5200–5213

Article  CAS  PubMed  Google Scholar 

Jiang X, Zhou Y, Sun AJ, Xue JL (2018) NEAT1 contributes to breast cancer progression through modulating miR-448 and ZEB1. J Cell Physiol 233:8558–8566

Article  CAS  PubMed  Google Scholar 

Jin H, Du W, Huang W, Yan J, Tang Q, Chen Y, Zou Z (2021) lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment. Molecular Therapy-Nucleic Acids 25:613–637

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kataki AC, Tiwari P, Thilagavthi R, Krishnatreya M (2023) Epidemiology of Gynaecological Cancers. In Fundamentals in Gynaecologic Malignancy. Springer, 1–8

Google Scholar 

Ke H, Zhao L, Feng X, Xu H, Zou L, Yang Q, Su X, Peng L, Jiao B (2016) NEAT1 is required for survival of breast cancer cells through FUS and miR-548. Gene Regul Syst Biol 10:11–17

CAS  Google Scholar 

Klec C, Prinz F, Pichler M (2019) Involvement of the long noncoding RNA NEAT 1 in carcinogenesis. Mol Oncol 13:46–60

Article  CAS  PubMed  Google Scholar 

Klinge CM (2018) Non-coding RNAs in breast cancer: intracellular and intercellular communication. Non-Coding RNA 4:40

Article  CAS  PubMed  PubMed Central  Google Scholar 

Knutsen E, Lellahi SM, Aure MR, Nord S, Fismen S, Larsen KB, Gabriel MT, Hedberg A, Bjørklund SS, Bofin AM et al (2020) The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers. Sci Rep 10:1277

Article  CAS  PubMed  PubMed Central  Google Scholar 

Knutsen E, Harris AL, Perander M (2022) Expression and functions of long non-coding RNA NEAT1 and isoforms in breast cancer. Br J Cancer 126:551–561

Article  CAS  PubMed  Google Scholar 

Kopp F, Mendell JT (2018) Functional classification and experimental dissection of long noncoding RNAs. Cell 172:393–407

Article  CAS 

留言 (0)

沒有登入
gif