Early persistence on therapy impacts drug-free remission: a case-control study in a cohort of Hispanic patients with recent-onset rheumatoid arthritis

Smolen JS, Landewé RBM, Bijlsma JWJ, Burmester GR, Dougados M, Kerschbaumer A, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. J Ann Rheum Dis. 2020;79:685–99.

CAS  PubMed  Article  Google Scholar 

Verstappen M, van Mulligen E, de Jong PHP, van der Helm-van Mil AHM. DMARD-free remission as novel treatment target in rheumatoid arthritis: a systematic literature review of achievability and sustainability. RMD Open. 2020;6:1–13.

Article  Google Scholar 

Gul H, Harnden K, Saleem BL. Defining the optimal strategies for achieving drug-free remission in rheumatoid arthritis: a narrative review. Healthcare. 2021;9:1–20.

Article  Google Scholar 

Filipowicz-Sosnowska A. Drug-free remission: the goal of the future in management of patients with rheumatoid arthritis. Reumatologia. 2017;55:284–9.

PubMed  PubMed Central  Article  Google Scholar 

Ajeganova S, van Steenbergen HW, van Nies JA, Hamburguesas LE, Huizinga TWJ, van der Helm-van Mil AHM. Disease-modifying antirheumatic drug-free sustained remission in rheumatoid arthritis: an increasingly achievable outcome with subsidence of disease symptoms. Ann Rheum Dis. 2016;75:867–73.

CAS  PubMed  Article  Google Scholar 

Scott IC, Kingsley GH, Scott DL. Can we discontinue synthetic disease-modifying anti-rheumatic drugs in rheumatoid arthritis? Clin Exp Rheumatol. 2013;31(Suppl):S4–8.

PubMed  Google Scholar 

van Nies JA, Tsonaka R, Gaujoux-Viala C, Fautrel B, van der Helm-van Mil AHM. Evaluating relationships between symptom duration and persistence of rheumatoid arthritis: does a window of opportunity exist? Results on the Leiden early arthritis clinic and ESPOIR cohorts. Ann Rheum Dis. 2015;74:806–12.

PubMed  Article  Google Scholar 

Brown AK, Conaghan PG, Karim Z, Quinn MA, Ikeda K, Peterfy CG, et al. An explanation for the apparent dissociation between clinical remission and continued structural deterioration in rheumatoid arthritis. Arthritis Rheum. 2008;58:2958–67.

CAS  PubMed  Article  Google Scholar 

Klarenbeek NB, van der Kooij SM, Guler-Yuksel M, van Groenendael JH, Han KH, Kerstens PJ, et al. Discontinuing treatment in patients with rheumatoid arthritis in sustained clinical remission: exploratory analyses from the BeSt study. Ann Rheum Dis. 2011;70:315–9.

CAS  PubMed  Article  Google Scholar 

Kuijper TM, Luime JJ, de Jong PH, Gerards AH, van Zeben D, Tchetverikov I, et al. Tapering conventional synthetic DMARDs in patients with early arthritis in sustained remission: 2-year follow-up of the tREACH trial. Ann Rheum Dis. 2016;75:2119–23.

CAS  PubMed  Article  Google Scholar 

Baker KF, Skelton AJ, Lendrem DW, Scadeng A, Thompson B, Pratt AG, et al. Predicting drug-free remission in rheumatoid arthritis: a prospective interventional cohort study. J Autoimmun. 2019;105:1–8.

Article  Google Scholar 

van der Woude D, Young A, Jayakumar K, Mertens BJ, Toes RE, van der Helm-van Mil AH, et al. Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts. Arthritis Rheum. 2009;60:2262–71.

PubMed  Article  Google Scholar 

Gul H, Ponchel F, Emery P. In RA patients in remission, which biomarkers predict successful tapering of csDMARDs? Ann Rheum Dis. 2021;80(Suppl 1):110.

Article  Google Scholar 

Hughes LD, Done J, Young A. A 5-item version of the Compliance Questionnaire for Rheumatology (CQR5) successfully identifies low adherence to DMARDs. BMC Musculoskelet Disord. 2013;14:286.

PubMed  PubMed Central  Article  Google Scholar 

Murage MJ, Tongbram V, Feldman SR, Malatestinic WN, Larmore CJ, Muram TM, et al. Medication adherence and persistence in patients with rheumatoid arthritis, psoriasis, and psoriatic arthritis: a systematic literature review. Patient Prefer Adherence. 2018;12:1483–503.

PubMed  PubMed Central  Article  Google Scholar 

van den Bemt BJ, Zwikker HE, van den Ende CH. Medication adherence in patients with rheumatoid arthritis: a critical appraisal of the existing literature. Expert Rev Clin Immunol. 2012;8:337–51.

PubMed  Article  CAS  Google Scholar 

Pasma A, van’t Spijker A, Hazes JMW, Busschbach JJV, Luime JJ. Factors associated with adherence to pharmaceutical treatment for rheumatoid arthritis patients: a systematic review. Semin Arthritis Rheum. 2013;43:18–28.

PubMed  Article  Google Scholar 

Salt E, Frazier SK. Adherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a narrative review of the literature. Orthop Nurs. 2010;29:260–75.

PubMed  PubMed Central  Article  Google Scholar 

Blum MA, Koo D, Doshi JA. Measurement and rates of persistence with and adherence to biologics for rheumatoid arthritis: a systematic review. Clin Ther. 2011;33:901–13.

PubMed  Article  Google Scholar 

Gossec L, Tubach F, Dougados M, Ravaud P. Reporting of adherence to medication in recent randomized controlled trials of 6 chronic diseases: a systematic literature review. Am J Med Sci. 2007;334:248–54.

PubMed  Article  Google Scholar 

De Achaval S, Suarez-Almazor ME. Treatment adherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis and systemic lupus erythematosus. Int J Clin Rheumatol. 2010;5:313–26.

Article  Google Scholar 

Viller F, Guillemin F, Briançon S, Moum T, Suurmeijer T, van den Heuvel W. Compliance with drug therapy in rheumatoid arthritis. A longitudinal European study. Joint Bone Spine. 2000;67:178–82.

CAS  PubMed  Google Scholar 

Contreras-Yañez I, Ponce-De Leon S, Cabiedes J, Rull-Gabayet M, Pascual-Ramos V. Inadequate therapy behavior is associated to disease flares in patients with rheumatoid arthritis who have achieved remission with disease-modifying anti-rheumatic drugs. Am Med Sci. 2010;340:282–90.

Article  Google Scholar 

Contreras-Yáñez I, Cabiedes J, Villa AR, Rull-Gabayet M, Pascual-Ramos V. Persistence on therapy is a major determinant of patient-, physician-, and laboratory reported outcomes in recent-onset rheumatoid arthritis patients. Clin Exp Rheumatol. 2010;28:748–51.

PubMed  Google Scholar 

Contreras- Yáñez I, Pascual-Ramos V. Predictors of health care dropout in an inception cohort of patients with early-onset rheumatoid arthritis. BMC Musculoskeletal Dis. 2017;18:1–9.

Article  Google Scholar 

Pincus T, O’Dell JR, Kremer JM. Combination therapy with multiple disease-modifying antirheumatic drugs in rheumatoid arthritis: a preventive strategy. Ann Intern Med. 1999;131(10):768–74.

CAS  PubMed  Article  Google Scholar 

Smolen JS, Aletaha D, Bijlsma JW, et al. Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis. 2010;69(4):631–7.

PubMed  Article  Google Scholar 

Emery P, Salmon M. Early rheumatoid arthritis: time to aim for remission? Ann Rheum Dis. 1995;54(12):944–7.

Aletaha D, Ward MM, Machold KP, Nell VP, Stamm T, Smolen JS. Remission and active disease in rheumatoid arthritis: Defining criteria for disease activity states. Arthritis Rheum. 2005;52(9):2625-36. https://doi.org/10.1002/art.21235.

Gul H, Ferreira J, Emery P. Remission in rheumatoid arthritis: is it all the same? Expert Rev Clin Pharmacol. 2015;8:575–86.

CAS  PubMed  Article  Google Scholar 

Prevoo M, van’t Hof M, Kuper H, van Leeuwen M, van de Putte L, van Riel P. Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 1995;38:44–8.

CAS  PubMed  Article  Google Scholar 

Mody G, Cardiel M. Challenges in the management of rheumatoid arthritis in developing countries. Best Pract Res Clin Rheumatol. 2008;22:621–41.

PubMed  Article  Google Scholar 

Massardo L, Pons-Estel B, Wojdyla D, Cardiel M, Galarza-Maldonado C, Furst DE, et al. Early rheumatoid arthritis in Latin America: low socioeconomic status related to high disease activity at baseline. Arthritis Care Res. 2012;64:1135–43.

Google Scholar 

Klerk E, van der Heijde D, Landewé R, van der Tempel H, Urquhart J, van der Linden S. Patient compliance in rheumatoid arthritis, polymyalgia rheumatica, and gout. J Rheumatol. 2003;30:44–54.

PubMed  Google Scholar 

Deyo R, Inui T, Sullivan B. Noncompliance with arthritis drugs: magnitude, correlates, and clinical implications. J Rheumatol. 1981;8:931–6.

CAS  PubMed  Google Scholar 

Tuncay R, Eksioglu E, Cakir B, Gurcay E, Cakci A. Factors affecting drug treatment compliance in patients with rheumatoid arthritis. Rheumatol Int. 2007;27:743–6.

PubMed  Article  Google Scholar 

Garcia-Gonzalez A, Richardson M, Popa-Lisseanu M, Cox V, Kallen M, Janssen N. Treatment adherence in patients with rheumatoid arthritis and systemic lupus erythematosus. Clin Rheumatol. 2008;27:883–9.

PubMed  Article  Google Scholar 

Lorish C, Richards B, Brown S. Perspective of the patient with rheumatoid arthritis on issues related to missed medication. Arthritis Care Res. 1990;3:78–84.

CAS  PubMed  Google Scholar 

Grijalva C, Chung C, Arbogast P, Stein C, Mitchel E, Griffin M. Assessment of adherence to and persistence on disease-modifying antirheumatic drugs (DMARDs) in patients with rheumatoid arthritis. Med Care. 2007;45:66–76.

Article  Google Scholar 

Curkendall S, Patel V, Gleeson M, Campbell R, Zagari M, Dubois R. Compliance with biologic therapies for rheumatoid arthritis: do patients out-of-pocket payments matter? Arthritis Rheum. 2008;59:1519–26.

CAS  PubMed  Article  Google Scholar 

Hoon L, Pullenayegu E, Moinedding R, Gladman D, Silverman E, Feldman B. Methods for analyzing observational longitudinal prognosis studies for rheumatic diseases: a review and worked example using a clinic-based cohort of juvenile dermatomyositis patients. Pediatr Rheumatol. 2017;29:15–8.

Google Scholar 

Cush J. Early rheumatoid arthritis – is there a window of opportunity? J Rheumatol. 2007;80 Suppl:1–7.

Google Scholar 

Contreras-Yáñez I, Pascual-Ramos V. Window of opportunity to achieve major outcomes in early rheumatoid arthritis patients: how persistence with therapy matters. Arthritis Res Ther. 2015;17:1–9.

Article  Google Scholar 

Nell V, Machold K, Eberl G, Stamm T, Uffman M, Smolen J. Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology. 2004;43:906–14.

CAS  PubMed  Article  Google Scholar 

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