Enteral nutrition ameliorates the symptoms of Crohn's disease in mice via activating special pro-resolving mediators through innate lymphoid cells

1. Torres, J, Mehandru, S, Colombel, JF, et al. Crohn's disease. Lancet (London, England) 2017; 389: 1741–1755.
Google Scholar | Crossref | Medline2. Shah, SC, Colombel, JF, Sands, BE, et al. Systematic review with meta-analysis: mucosal healing is associated with improved long-term outcomes in Crohn's Disease. Aliment Pharmacol Ther 2016; 43: 317–333.
Google Scholar | Crossref | Medline | ISI3. Basil, MC, Levy, BD. Specialized pro-resolving mediators: endogenous regulators of infection and inflammation. Nat Rev Immunol 2016; 16: 51–67.
Google Scholar | Crossref | Medline | ISI4. Serhan, CN . Pro-resolving lipid mediators are leads for resolution physiology. Nature 2014; 510: 92–101.
Google Scholar | Crossref | Medline | ISI5. Serhan, CN, Dalli, J, Colas, RA, et al. Protectins and maresins: new pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome. Biochim Biophys Acta. 2015; 1851: 397–413.
Google Scholar | Crossref | Medline | ISI6. Serhan, CN, Savill, J. Resolution of inflammation: the beginning programs the end. Nat Immunol 2005; 6: 1191–1197.
Google Scholar | Crossref | Medline | ISI7. Buckley, CD, Gilroy, DW, Serhan, CN. Proresolving lipid mediators and mechanisms in the resolution of acute inflammation. Immunity 2014; 40: 315–327.
Google Scholar | Crossref | Medline8. Kasuga, K, Yang, R, Porter, TF, et al. Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. Journal of immunology (Baltimore, Md : 1950) 2008; 181: 8677–8687.
Google Scholar | Crossref | Medline9. Serhan, CN, Sheppard, KA. Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro. J Clin Invest 1990; 85: 772–780.
Google Scholar | Crossref | Medline10. Levy, BD, Romano, M, Chapman, HA, et al. Human alveolar macrophages have 15–lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. J Clin Invest 1993; 92: 1572–1579.
Google Scholar | Crossref | Medline11. Tułowiecka, N, Kotlęga, D, Prowans, P, et al. The role of resolvins: ePA and DHA derivatives can be useful in the prevention and treatment of ischemic stroke. Int J Mol Sci 2020; 21: 7628.
Google Scholar | Crossref | Medline12. Serhan, CN, Hong, S, Gronert, K, et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 2002; 196: 1025–1037.
Google Scholar | Crossref | Medline | ISI13. Duvall, MG, Levy, BD. DHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation. Eur J Pharmacol 2016; 785: 144–155.
Google Scholar | Crossref | Medline14. Lambertsen, KL, Biber, K, Finsen, B. Inflammatory cytokines in experimental and human stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012; 32: 1677–1698.
Google Scholar | SAGE Journals | ISI15. Perretti, M, D’Acquisto, F. Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol 2009; 9: 62–70.
Google Scholar | Crossref | Medline | ISI16. Wang, B, Gong, X, Wan, JY, et al. Resolvin D1 protects mice from LPS-induced acute lung injury. Pulm Pharmacol Ther 2011; 24: 434–441.
Google Scholar | Crossref | Medline17. Liao, Z, Dong, J, Wu, W, et al. Resolvin D1 attenuates inflammation in lipopolysaccharide-induced acute lung injury through a process involving the PPARγ/NF-κB pathway. Respir Res 2012; 13: 110.
Google Scholar | Crossref | Medline | ISI18. Spite, M, Norling, LV, Summers, L, et al. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 2009; 461: 1287–1291.
Google Scholar | Crossref | Medline | ISI19. Dalli, J, Winkler, JW, Colas, RA, et al. Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents. Chem Biol  2013; 20: 188–201.
Google Scholar | Crossref | Medline20. Jang, H, Lee, J, Park, S, et al. Baicalein mitigates radiation-induced enteritis by improving endothelial dysfunction. Front Pharmacol 2019; 10: 892.
Google Scholar | Crossref | Medline21. Dalli, J, Colas, RA, Arnardottir, H, et al. Vagal regulation of group 3 innate lymphoid cells and the immunoresolvent PCTR1 controls infection resolution. Immunity 2017; 46: 92–105.
Google Scholar | Crossref | Medline22. Colas, RA, Shinohara, M, Dalli, J, et al. Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue. Am J Physiol Cell Physiol 2014; 307: C39–C54.
Google Scholar | Crossref | Medline23. Rowat, A . Enteral tube feeding for dysphagic stroke patients. Br J Nurs 2015; 24: 138, 40, 42–5.
Google Scholar | Crossref | Medline24. Catangui, EJ, Slark, J. Nurse-led ward rounds: a valuable contribution to acute stroke care. Br J Nurs 2012; 21: 801–805.
Google Scholar | Crossref | Medline25. Seok, J, Warren, HS, Cuenca, AG, et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A 2013; 110: 3507–3512.
Google Scholar | Crossref | Medline | ISI26. Kakodkar, S, Mutlu, EA. Diet as a therapeutic option for adult inflammatory bowel disease. Gastroenterol Clin North Am 2017; 46: 745–767.
Google Scholar | Crossref | Medline27. Comeche, JM, Caballero, P, Gutierrez-Hervas, A, et al. Enteral nutrition in patients with inflammatory bowel disease. Systematic review, meta-analysis, and meta-regression. Nutrients 2019; 11: 2657.
Google Scholar28. Atreya, I, Kindermann, M, Wirtz, S. Innate lymphoid cells in intestinal cancer development. Semin Immunol 2019; 41: 101267.
Google Scholar | Crossref | Medline29. Withers, DR Innate lymphoid cell regulation of adaptive immunity. Immunology 2016; 149: 123–130.
Google Scholar | Crossref | Medline30. Eken, A, Singh, AK, Treuting, PM, et al. IL-23R+innate lymphoid cells induce colitis via interleukin-22-dependent mechanism. Mucosal Immunol 2014; 7: 143–154.
Google Scholar | Crossref | Medline31. Zeng, B, Shi, S, Ashworth, G, et al. ILC3 Function as a double-edged sword in inflammatory bowel diseases. Cell Death Dis 2019; 10: 315.
Google Scholar | Crossref | Medline32. Zhao, D, Cai, C, Zheng, Q, et al. Vancomycin pre-treatment impairs tissue healing in experimental colitis: importance of innate lymphoid cells. Biochem Biophys Res Commun 2017; 483: 237–244.
Google Scholar | Crossref | Medline33. Werz, O, Gerstmeier, J, Libreros, S, et al. Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity. Nat Commun 2018; 9: 59.
Google Scholar | Crossref | Medline34. Zhang, R, He, GZ, Wang, YK, et al. Omega-3 polyunsaturated fatty acids inhibit the increase in cytokines and chemotactic factors induced in vitro by lymph fluid from an intestinal ischemia-reperfusion injury model. Nutrition (Burbank, Los Angeles County. Calif 2015; 31: 508–514.
Google Scholar35. Norris, PC, Serhan, CN. Metabololipidomic profiling of functional immunoresolvent clusters and eicosanoids in mammalian tissues. Biochem Biophys Res Commun 2018; 504: 553–561.
Google Scholar | Crossref | Medline36. Gerstmeier, J, Kretzer, C, Di Micco, S, et al. Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: a promising pharmacological strategy for anti-inflammatory therapy. Biochem Pharmacol 2019; 165: 263–274.
Google Scholar | Crossref | Medline37. Mbodji, K, Charpentier, C, Guérin, C, et al. Adjunct therapy of n-3 fatty acids to 5-ASA ameliorates inflammatory score and decreases NF-κB in rats with TNBS-induced colitis. J Nutr Biochem 2013; 24: 700–705.
Google Scholar | Crossref | Medline38. Hooper, KM, Barlow, PG, Stevens, C, et al. Inflammatory bowel disease drugs: a focus on autophagy. Journal of Crohn's & colitis 2017; 11: 118–127.
Google Scholar | Crossref | Medline39. Kikut, J, Konecka, N, Ziętek, M, et al. Diet supporting therapy for inflammatory bowel diseases. Eur J Nutr 2021; 60: 2275–2291.
Google Scholar | Crossref | Medline40. Julia, C, Meunier, N, Touvier, M, et al. Dietary patterns and risk of elevated C-reactive protein concentrations 12 years later. Br J Nutr 2013; 110: 747–754.
Google Scholar | Crossref | Medline41. Schreiner, P, Martinho-Grueber, M, Studerus, D, et al. Nutrition in inflammatory bowel disease. Digestion 2020; 101: 120–135.
Google Scholar | Crossref | Medline42. Zaloga, GP . Narrative review of n-3 polyunsaturated fatty acid supplementation upon immune functions, resolution molecules and lipid peroxidation. Nutrients 2021; 13: 662.
Google Scholar | Crossref | Medline

留言 (0)

沒有登入
gif