The alleles of AGT and HIF1A gene affect the risk of hypertension in plateau residents

1. Kato, N, Takeuchi, F, Tabara, Y, Kelly, TN, Go, MJ, Sim, X, Tay, WT, Chen, CH, Zhang, Y, Yamamoto, K, Katsuya, T, Yokota, M, Kim, YJ, Ong, RT, Nabika, T, Gu, D, Chang, LC, Kokubo, Y, Huang, W, Ohnaka, K, Yamori, Y, Nakashima, E, Jaquish, CE, Lee, JY, Seielstad, M, Isono, M, Hixson, JE, Chen, YT, Miki, T, Zhou, X, Sugiyama, T, Jeon, JP, Liu, JJ, Takayanagi, R, Kim, SS, Aung, T, Sung, YJ, Zhang, X, Wong, TY, Han, BG, Kobayashi, S, Ogihara, T, Zhu, D, Iwai, N, Wu, JY, Teo, YY, Tai, ES, Cho, YS, He, J. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet 2011; 43:531–8
Google Scholar | Crossref | Medline | ISI2. Muñoz, M, Pong-Wong, R, Canela-Xandri, O, Rawlik, K, Haley, CS, Tenesa, A. Evaluating the contribution of genetics and familial shared environment to common disease using the UK biobank. Nat Genet 2016; 48:980–3
Google Scholar | Crossref | Medline3. Parati, G, Agostoni, P, Basnyat, B, Bilo, G, Brugger, H, Coca, A, Festi, L, Giardini, G, Lironcurti, A, Luks, AM, Maggiorini, M, Modesti, PA, Swenson, ER, Williams, B, Bärtsch, P, Torlasco, C. Clinical recommendations for high altitude exposure of individuals with pre-existing cardiovascular conditions: a joint statement by the European Society of Cardiology, the Council on Hypertension of the European Society of Cardiology, the European Society of hypertension, the International Society of Mountain Medicine, the Italian Society of Hypertension and the Italian Society of Mountain medicine. Eur Heart J 2018; 39:1546–54
Google Scholar | Medline4. Aryal, N, Weatherall, M, Bhatta, YK, Mann, S. Blood pressure and hypertension in adults permanently living at high altitude: a systematic review and meta-analysis. High Alt Med Biol 2016; 17:185–93
Google Scholar | Crossref | Medline5. Yue, L, Fan, Z, Sun, L, Feng, W, Li, J. Prevalence of essential hypertension and its complications among Chinese population at high altitude. High Alt Med Biol 2017; 18:140–4
Google Scholar | Crossref | Medline6. Liu, J. Highlights of the 2018 Chinese hypertension guidelines. Clin Hypertens 2020; 26:8
Google Scholar | Crossref | Medline7. Gesang, L, Liu, G, Cen, W, Qiu, C, Zhuoma, C, Zhuang, L, Ren, D, Pincuo, Z, Chan, Y. Angiotensin-converting enzyme gene polymorphism and its association with essential hypertension in a Tibetan population. Hypertens Res 2002; 25:481–5
Google Scholar | Crossref | Medline | ISI8. Wellcome Trust Case Control Consortium . Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661–78
Google Scholar | Crossref | Medline | ISI9. Guo, Y, Tomlinson, B, Chu, T, Fang, YJ, Gui, H, Tang, CS, Yip, BH, Cherny, SS, Hur, YM, Sham, PC, Lam, TH, Thomas, NG. A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits. PLoS One 2012; 7:e31489
Google Scholar | Crossref | Medline10. Padmanabhan, S, Caulfield, M, Dominiczak, AF. Genetic and molecular aspects of hypertension. Circ Res 2015; 116:937–59
Google Scholar | Crossref | Medline11. Russo, A, Di Gaetano, C, Cugliari, G, Matullo, G. Advances in the genetics of hypertension: the effect of rare variants. Ijms 2018; 19:688
Google Scholar | Crossref12. Kolifarhood, G, Daneshpour, MS, Khayat, BS, Saadati, HM, Guity, K, Khosravi, N, Akbarzadeh, M, Sabour, S. Generality of genomic findings on blood pressure traits and its usefulness in precision medicine in diverse populations: a systematic review. Clin Genet 2019; 96:17–27
Google Scholar | Crossref | Medline13. Padmanabhan SDominiczak, AF. Genomics of hypertension: the road to precision medicine. Nat Rev Cardiol 2021; 18:235–50
Google Scholar | Crossref | Medline14. Yang, HC, Liang, YJ, Chen, JW, Chiang, KM, Chung, CM, Ho, HY, Ting, CT, Lin, TH, Sheu, SH, Tsai, WC, Chen, JH, Leu, HB, Yin, WH, Chiu, TY, Chern, CL, Lin, SJ, Tomlinson, B, Guo, Y, Sham, PC, Cherny, SS, Lam, TH, Thomas, GN, Pan, WH. Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study. PLoS One 2012; 7:e32907
Google Scholar | Crossref | Medline15. Yamada, Y, Kato, K, Oguri, M, Horibe, H, Fujimaki, T, Yasukochi, Y, Takeuchi, I, Sakuma, J. Identification of 13 novel susceptibility loci for early-onset myocardial infarction, hypertension, or chronic kidney disease. Int J Mol Med 2018; 42:2415–36
Google Scholar | Medline16. Inoue, I, Nakajima, T, Williams, CS, Quackenbush, J, Puryear, R, Powers, M, Cheng, T, Ludwig, EH, Sharma, AM, Hata, A, Jeunemaitre, X, Lalouel, JM. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest 1997; 99:1786–97
Google Scholar | Crossref | Medline | ISI17. Liu, Y, Qin, W, Hou, S, Shan, G, Zhuo, M, Chen, Y, Cui, C, Caidan, L, Qiu, C. A-6G variant of the angiotensinogen gene and essential hypertension in Han, Tibetan, and Yi populations. Hypertens Res 2001; 24:159–63
Google Scholar | Crossref | Medline | ISI18. Pandey, P, Mohammad, G, Singh, Y, Pasha, MA. Polymorphisms and haplotype of ROCK2 associate with high altitude essential hypertension in native high altitude Ladakhi Indian population: a preliminary study. Clin Exp Hypertens 2016; 38:238–44
Google Scholar | Crossref | Medline19. Rysz, J, Franczyk, B, Rysz-Górzyńska, M, Gluba-Brzózka, A. Pharmacogenomics of hypertension treatment. Ijms 2020; 21:4709
Google Scholar | Crossref20. Tragante, V, Hemerich, D, Alshabeeb, M, Brænne, I, Lempiäinen, H, Patel, RS, den Ruijter, HM, Barnes, MR, Moore, JH, Schunkert, H, Erdmann, J, Asselbergs, FW. Druggability of coronary artery disease risk loci. Circ Genom Precis Med 2018; 11:e001977
Google Scholar | Crossref | Medline21. Jhamb, D, Magid-Slav, M, Hurle, MR, Agarwal, P. Pathway analysis of GWAS loci identifies novel drug targets and repurposing opportunities. Drug Discov Today 2019; 24:1232–6
Google Scholar | Crossref | Medline22. Beitelshees, AL, Gong, Y, Wang, D, Schork, NJ, Cooper-Dehoff, RM, Langaee, TY, Shriver, MD, Sadee, W, Knot, HJ, Pepine, CJ, Johnson, JA; INVEST Investigators . KCNMB1 genotype influences response to erapamil SR and adverse outcomes in the INternational VErapamil SR/trandolapril STudy (INVEST). Pharmacogenet Genomics 2007; 17:719–29
Google Scholar | Crossref | Medline23. Li, H, Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 2009; 25:1754–60
Google Scholar | Crossref | Medline | ISI24. McKenna, A, Hanna, M, Banks, E, Sivachenko, A, Cibulskis, K, Kernytsky, A, Garimella, K, Altshuler, D, Gabriel, S, Daly, M, DePristo, MA. The genome analysis toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res 2010; 20:1297–303
Google Scholar | Crossref | Medline | ISI25. Danecek, P, Auton, A, Abecasis, G, Albers, CA, Banks, E, DePristo, MA, Handsaker, RE, Lunter, G, Marth, GT, Sherry, ST, McVean, G, Durbin, R; 1000 Genomes Project Analysis Group . The variant call format and VCFtools. Bioinformatics 2011; 27:2156–8
Google Scholar | Crossref | Medline | ISI26. Purcell, S, Neale, B, Todd-Brown, K, Thomas, L, Ferreira, MA, Bender, D, Maller, J, Sklar, P, de Bakker, PI, Daly, MJ, Sham, PC. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81:559–75
Google Scholar | Crossref | Medline | ISI27. Anderson, CA, Pettersson, FH, Clarke, GM, Cardon, LR, Morris, AP, Zondervan, KT. Data quality control in genetic case-control association studies. Nat Protoc 2010; 5:1564–73
Google Scholar | Crossref | Medline | ISI28. Solé, X, Guinó, E, Valls, J, Iniesta, R, Moreno, V. SNPStats: a web tool for the analysis of association studies. Bioinformatics 2006; 22:1928–9
Google Scholar | Crossref | Medline | ISI29. Bland, JM, Altaian, DG. Statistics notes. The odds ratio. Bmj 2000; 320:1468
Google Scholar | Crossref | Medline30. Moore, LG, Niermeyer, S, Zamudio, S. Human adaptation to high altitude: regional and life-cycle perspectives. Am J Phys Anthropol 1998; 27:25–64
Google Scholar | Crossref | Medline31. Mopidevi, B, Kaw, MK, Sivankutty, I, Jain, S, Perla, SK, Kumar, A. A polymorphism in intron I of the human angiotensinogen gene (hAGT) affects binding by HNF3 and hAGT expression and increases blood pressure in mice. J Biol Chem 2019; 294:11829–39
Google Scholar | Crossref | Medline32. Kolifarhood, G, Daneshpour, MS, Zahedi, AS, Khosravi, N, Sedaghati-Khayat, B, Guity, K, Rasekhi Dehkordi, S, Amiri Roudbar, M, Ghanbari, F, Hadaegh, F, Azizi, F, Akbarzadeh, M, Sabour, S. Familial genetic and environmental risk profile and high blood pressure event: a prospective cohort of cardio-metabolic and genetic study. Blood Press 2021; 30:196–204
Google Scholar | Crossref | Medline33. Chen, L, Qian, H, Luo, Z, Li, D, Xu, H, Chen, J, He, P, Zhou, X, Zhang, T, Chen, J, Min, X. PHACTR1 gene polymorphism with the risk of coronary artery disease in Chinese Han population. Postgrad Med J 2019; 95:67–71
Google Scholar | Crossref | Medline34. Rodríguez-Pérez, JM, Blachman-Braun, R, Pomerantz, A, Vargas-Alarcón, G, Posadas-Sánchez, R, Pérez-Hernández, N. Possible role of intronic polymorphisms in the PHACTR1 gene on the development of cardiovascular disease. Med Hypotheses 2016; 97:64–70
Google Scholar | Crossref | Medline35. Kiando, SR, Tucker, NR, Castro-Vega, LJ, Katz, A, D'Escamard, V, Tréard, C, Fraher, D, Albuisson, J, Kadian-Dodov, D, Ye, Z, Austin, E, Yang, ML, Hunker, K, Barlassina, C, Cusi, D, Galan, P, Empana, JP, Jouven, X, Gimenez-Roqueplo, AP, Bruneval, P, Hyun Kim, ES, Olin, JW, Gornik, HL, Azizi, M, Plouin, PF, Ellinor, PT, Kullo, IJ, Milan, DJ, Ganesh, SK, Boutouyrie, P, Kovacic, JC, Jeunemaitre, X, Bouatia-Naji, N. PHACTR1 is a genetic susceptibility locus for fibromuscular dysplasia supporting its complex genetic pattern of inheritance. PLoS Genet 2016; 12:e1006367
Google Scholar | Crossref | Medline36. Gupta, RM, Hadaya, J, Trehan, A, Zekavat, SM, Roselli, C, Klarin, D, Emdin, CA, Hilvering, CRE, Bianchi, V, Mueller, C, Khera, AV, Ryan, RJH, Engreitz, JM, Issner, R, Shoresh, N, Epstein, CB, de Laat, W, Brown, JD, Schnabel, RB, Bernstein, BE, Kathiresan, S. A genetic variant associated with five vascular diseases is a distal regulator of endothelin-1 gene expression. Cell 2017; 170:522–33.e15
Google Scholar | Crossref | Medline37. Schiffrin, EL. Does endothelin-1 raise or lower blood pressure in humans? Nephron 2018; 139:47–50
Google Scholar | Crossref | Medline38. Sheng, ZL, Ju, CW, Yan, GL, Chen, ZP, Pan, XD, Lu, WB, Yao, YY, Ma, GS. The relevance of HIF1A gene polymorphisms and primary hypertensive left ventricular hypertrophy in Chinese Han population. Eur Rev Med Pharmacol Sci 2019; 23:8095–100
Google Scholar | Medline

留言 (0)

沒有登入
gif