Brain interleukins and Alzheimer’s disease

Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL (2003) Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 278:1910–1914

Article  CAS  PubMed  Google Scholar 

Ahmed T, Setzer N, Fazel Nabavi S, Erdogan Orhan I, Braidy N, Sobarzo-Sanchez E et al (2016) Insights into effects of ellagic acid on the nervous system: a mini review. Curr Pharmaceut Des 22:1350–1360

Article  CAS  Google Scholar 

Alsadany MA, Shehata HH, Mohamad MI, Mahfouz RG (2013) Histone deacetylases enzyme, copper, and IL-8 levels in patients with Alzheimer’s disease. Am J Alzh Dis Other Demen 28:54–61

Article  Google Scholar 

Alves S, Churlaud G, Audrain M, Michaelsen-Preusse K, Fol R, Souchet B, Braudeau J et al (2017) Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer’s disease mice. Brain 140:826–842

PubMed  Google Scholar 

Alves de Lima K, Rustenhoven J, Da Mesquita S, Wall M, Salvador AF et al (2020) Meningeal gd T cells regulate anxiety-like behavior via IL-17a signaling inneurons. Nat Immunol 21:1421–1429

Article  CAS  PubMed  Google Scholar 

Alzheimer’s Association (2023) Alzheimer’s disease facts and figures. Alzheimer’s Dement 19(4). https://doi.org/10.1002/alz.13016

Anderson G, Ojala JO (2010) Alzheimer’s and seizures: interleukin-18, indoleamine 2, 3-dioxygenase and quinolinic acid. Int J Trypt Res 3:IJTR–S4603

Google Scholar 

Aso Y, Okumura K, Takebayashi K, Wakabayashi S, Inukai T (2003) Relationships of plasma interleukin-18 concentrations to hyperhomocysteinemia and carotid intimal-media wall thickness in patients with type 2 diabetes. Diabet Care 26:2622–2627

Article  Google Scholar 

Bachis A, Colangelo AM, Vicini S, Doe PP, De Bernardi MA, Brooker G et al (2001) Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity. J Neurosci 21:3104–3112

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bagyinszky E, Van Giau V, Shim K, Suk K, An SSA, Kim S (2017) Role of inflammatory molecules in the Alzheimer’s disease progression and diagnosis. J Neurol Sci 376:242–254

Article  CAS  PubMed  Google Scholar 

Balschun D, Wetzel W, Del Rey A, Pitossi F, Schneider H, Zuschratter W et al (2004) Interleukin-6: a cytokine to forget. FASEB J 18:1788–1790

Article  CAS  PubMed  Google Scholar 

Barbour B, Szatkowski M, Ingledew N, Attwell D (1989) Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature 342:918–920

Article  CAS  PubMed  Google Scholar 

Barrientos RM, Hein AM, Frank MG, Watkins LR, Maier SF (2012) Intracisternal interleukin-1 receptor antagonist prevents postoperative cognitive decline and neuroinflammatory response in aged rats. J Neurosci 32:14641–14648

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barroeta-Espar I, Weinstock LD, Perez-Nievas BG, Meltzer AC, Chong MST, Amaral AC et al (2019) Distinct cytokine profiles in human brains resilient to Alzheimer’s pathology. Neurobiol Dis 121:327–337

Article  CAS  PubMed  Google Scholar 

Beck RD, King MA, Ha GK, Cushman JD, Huang Z et al (2005) IL-2 deficiency results in altered septal and hippocampal cytoarchitecture: relation to development and neurotrophins. J Neuroimmun 160:146–153

Beloosesky Y, Salman H, Bergman M, Bessler H, Djaldetti M (2002) Cytokine levels and phagocytic activity in patients with Alzheimer’s disease. Gerontology 48:128–132

Article  PubMed  Google Scholar 

Ben Achour S, Pascual O (2010) Glia: The many ways to modulate synaptic plasticity. Neurochem Int 57:440–445

Article  CAS  PubMed  Google Scholar 

Biber K, Pinto-Duarte A, Wittendorp MC, Dolga AM, Fernandes CC, Künzel JVFD (2008) Interleukin-6 upregulates neuronal adenosine A 1 receptors: implications for neuromodulation and neuroprotection. Neuropsychopharmacology 33:2237–2250

Article  CAS  PubMed  Google Scholar 

Bishnoi RJ, Palmer RF, Royall DR (2015) Serum interleukin (IL)-15 as a biomarker of Alzheimer’s disease. PLoS ONE 10:e0117282

Article  PubMed  PubMed Central  Google Scholar 

Blennow K, Hampel H, Weiner M, Zetterberg H (2010) Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol 6:131–144

Article  CAS  PubMed  Google Scholar 

Block ML, Hong JS (2005) Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog Neurobiol 76:77–98

Article  CAS  PubMed  Google Scholar 

Boche D, Perry VH, Nicoll JAR (2013) Activation patterns of microglia and their identification in the human brain. Neuropathol Appl Neurobiol 39:3–18

Article  CAS  PubMed  Google Scholar 

Bossù P, Ciaramella A, Moro ML, Bellincampi L, Bernardini S, Federici G et al (2007) Interleukin 18 gene polymorphisms predict risk and outcome of Alzheimer’s disease. J Neurol Neurosurg Psychiat 78:807–811

Article  PubMed  PubMed Central  Google Scholar 

Bossù P, Ciaramella A, Salani F, Vanni D, Palladino I, Caltagirone C et al (2010) Interleukin-18, from neuroinflammation to Alzheimer’s disease. Curr Pharmaceut Des 16:4213–4224

Article  Google Scholar 

Boutajangout A, Wisniewski T (2013) The innate immune system in Alzheimer’s disease. Int J CellBiol 2013:1–7

Article  Google Scholar 

Brabers N, Nottet H (2006) Role of the pro-inflammatory cytokines TNF-α and IL‐1β in HIV-associated dementia. Europ J Clin Invest 36:447–458

Article  CAS  PubMed  Google Scholar 

Bresnihan B (2001) The safety and efficacy of interleukin-1 receptor antagonist in the treatment of rheumatoid arthritis. Seminars Arthrit Rheumat 30:17–20

Article  CAS  Google Scholar 

Brigas HC, Ribeiro M, Coelho JE, Gomes R, Gomez-Murcia V, Carvalho K et al (2021) IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease. Cell Rep 36:109574

Article  CAS  PubMed  Google Scholar 

Brosseron F, Krauthausen M, Kummer M, Heneka MT (2014) Body fluid cytokine levels in mild cognitive impairment and Alzheimer’s disease: a comparative overview. Mol Neurobiol 50:534–544

Article  CAS  PubMed  PubMed Central  Google Scholar 

Burda JE, Bernstein AM, Sofroniew MV (2016) Astrocyte roles in traumatic brain injury. Exp Neurol 275:305–315

Article  CAS  PubMed  Google Scholar 

Burton MD, Johnson RW (2012) Interleukin-6 trans-signaling in the senescent mouse brain is involved in infection-related deficits in contextual fear conditioning. Brain Behav Immun 26:732–738

Article  CAS  PubMed  Google Scholar 

Butterfield DA, Lange MLB (2009) Multifunctional roles of enolase in Alzheimer’s disease brain: beyond altered glucose metabolism. J Neurochem 111:915–933

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cagnin A, Brooks DJ, Kennedy AM, Gunn RN, Myers R, Turkheimer FE et al (2001) In-vivo measurement of activated microglia in dementia. Lancet 358:461–467

Article  CAS  PubMed  Google Scholar 

Cao K, Liao X, Lu J, Yao S, Wu F, Zhu X, Shi D, Wen S, Liu L, Zhou H (2018) IL-33/ST2 plays a critical role in endothelial cell activation and microglia-mediated neuroinflammation modulation. J Neuroinflammation 15(1):136. https://doi.org/10.1186/s12974-018-1169-6

Cao M, Liu J, Zhang X, Wang Y, Hou Y, Song Q, Cui Y, Zhao Y, Wang P (2023) IL-17A promotes the progression of Alzheimer’s disease in APP/PS1 mice. Immun Ageing 20:74

Article  CAS  PubMed  PubMed Central  Google Scholar 

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