Alleviation of Diabetes Mellitus-Induced Reproductive Dysfunction by Chlorogenic Acid in Male Rats via Combating Redox Imbalance

Kumar R, Gupta A, Singh AK, Bishayee A, Pandey AK. The antioxidant and antihyperglycemic activities of bottlebrush plant (Callistemon lanceolatus) stem extracts. Med (Basel). 2020;7:11.

CAS  Google Scholar 

Singh AK, Rana HK, Singh V, Chand Yadav T, Varadwaj P, Pandey AK. Evaluation of antidiabetic activity of dietary phenolic compound chlorogenic acid in streptozotocin induced diabetic rats: molecular docking, molecular dynamics, in silico toxicity, in vitro and in vivo studies. Comput Biol Med. 2021;134:104462.

Article  CAS  PubMed  Google Scholar 

Ganguly R, Singh SV, Jaiswal K, Kumar R, Pandey AK. Modulatory effect of caffeic acid in alleviating diabetes and associated complications. World J Diabetes. 2023;14:62–75.

Article  PubMed  PubMed Central  Google Scholar 

Rana HK, Singh AK, Pandey AK. Antioxidants and infertility. In: Nabavi SM, Silva AS, editors. Antioxidants effects in health [internet]. Elsevier; 2022 [cited 2024 Jan 23]. pp. 741–54. Available from: https://www.sciencedirect.com/science/article/pii/B9780128190968000586

Shoorei H, Khaki A, Khaki AA, Hemmati AA, Moghimian M, Shokoohi M. The ameliorative effect of carvacrol on oxidative stress and germ cell apoptosis in testicular tissue of adult diabetic rats. Biomed Pharmacother. 2019;111:568–78.

Article  CAS  PubMed  Google Scholar 

Aitken RJ, Gibb Z, Baker MA, Drevet J, Gharagozloo P. Causes and consequences of oxidative stress in spermatozoa. Reprod Fertil Dev. 2016;28:1.

Article  CAS  PubMed  Google Scholar 

Temidayo So, Stefan SP. Diabetes mellitus and male infertility. Asian Pac J Reprod. 2018;7:6.

Article  Google Scholar 

Brzoska MM, Moniuszko-Jakoniuk J, Pilat-Marcinkiewicz B, Sawicki B. Liver and kidney function and histology in rats exposed to cadmium and ethanol. Alcohol Alcohol. 2003;38:2–10.

Article  CAS  PubMed  Google Scholar 

Barkabi-Zanjani S, Ghorbanzadeh V, Aslani M, Ghalibafsabbaghi A, Chodari L. Diabetes mellitus and the impairment of male reproductive function: possible signaling pathways. Diabetes Metab Syndr. 2020;14:1307–14.

Article  PubMed  Google Scholar 

ElBanna AH, Osman AS, Hossny A, ElBanna H, Abo El-Ela FI. Dose-dependent effects of taurine against testicular damage in a streptozotocin-induced type 1 diabetes mellitus rat model. Int J Immunopathol Pharmacol. 2023;37:3946320231172745.

Article  CAS  PubMed  Google Scholar 

Kumar S, Pandey AK. Chemistry and Biological activities of flavonoids: an overview. Sci World J. 2013;2013:162750.

Article  Google Scholar 

Singh AK, Singla RK, Pandey AK. Chlorogenic acid: a Dietary Phenolic Acid with Promising Pharmacotherapeutic potential. Curr Med Chem. 2023;30:3905–26.

Article  CAS  PubMed  Google Scholar 

Tang Y, Fang C, Shi J, Chen H, Chen X, Yao X. Antioxidant potential of chlorogenic acid in age-related eye diseases. Pharmacol Res Perspect. 2024;12:e1162.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Karthikesan K, Pari L, Menon VP. Protective effect of tetrahydrocurcumin and chlorogenic acid against streptozotocin–nicotinamide generated oxidative stress induced diabetes. J Funct Foods. 2010;2:134–42.

Article  CAS  Google Scholar 

Yan Y, Zhou X, Guo K, Zhou F, Yang H. Use of chlorogenic acid against diabetes mellitus and its complications. J Immunol Res. 2020;2020:1–6.

Google Scholar 

Rodríguez-Méndez AJ, Carmen-Sandoval W, Lomas-Soria C, Guevara-González RG, Reynoso-Camacho R, Villagran-Herrera ME, et al. Timbe (Acaciella Angustissima) pods extracts reduce the levels of glucose, insulin and improved physiological parameters, Hypolipidemic Effect, oxidative stress and renal damage in Streptozotocin-Induced Diabetic rats. Molecules. 2018;23:2812.

Article  PubMed  PubMed Central  Google Scholar 

Gupta A, Kumar R, Ganguly R, Singh AK, Rana HK, Pandey AK. Antioxidant, anti-inflammatory and hepatoprotective activities of terminalia bellirica and its bioactive component ellagic acid against diclofenac induced oxidative stress and hepatotoxicity. Toxicol Rep. 2021;8:44–52.

Article  PubMed  Google Scholar 

Roy VK, Chenkual L, Gurusubramanian G. Protection of testis through antioxidant action of Mallotus roxburghianus in alloxan-induced diabetic rat model. J Ethnopharmacol. 2015;176:268–80.

Article  CAS  PubMed  Google Scholar 

Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974;47:469–74.

Article  CAS  PubMed  Google Scholar 

Beers RF, Sizer IW. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem. 1952;195:133–40.

Article  CAS  PubMed  Google Scholar 

Habig WH, Jakoby WB. Assays for differentiation of glutathione S-transferases. Methods Enzymol. 1981;77:398–405.

Article  CAS  PubMed  Google Scholar 

Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959;82:70–7.

Article  CAS  PubMed  Google Scholar 

Niehaus WG, Samuelsson B. Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur J Biochem. 1968;6:126–30.

Article  CAS  PubMed  Google Scholar 

Jaiswal SK, Gupta VK, Siddiqi NJ, Sharma B. Curcumin mediated attenuation of carbofuran induced toxicity in the heart of Wistar rats. Cell Mol Biol (Noisy-le-grand). 2017;63:12–7.

Article  CAS  PubMed  Google Scholar 

Joshi T, Singh AK, Haratipour P, Sah AN, Pandey AK, Naseri R, et al. Targeting AMPK signaling pathway by natural products for treatment of diabetes mellitus and its complications. J Cell Physiol. 2019;234:17212–31.

Article  CAS  PubMed  Google Scholar 

He Z, Yin G, Li QQ, Zeng Q, Duan J. Diabetes Mellitus causes male Reproductive dysfunction: a review of the evidence and mechanisms. Vivo. 2021;35:2503–11.

Article  CAS  Google Scholar 

Rabbani SI, Devi K, Khanam S. Inhibitory effect of glimepiride on nicotinamide-streptozotocin induced nuclear damages and sperm abnormality in diabetic Wistar rats. Indian J Exp Biol. 2009;47:804–10.

CAS  PubMed  Google Scholar 

Tošović J, Marković S, DimitrićMarković JM, Mojović M, Milenković D. Antioxidative mechanisms in chlorogenic acid. Food Chem. 2017;237:390–8.

Article  PubMed  Google Scholar 

Farzaei MH, Singh AK, Kumar R, Croley CR, Pandey AK, Coy-Barrera E, et al. Targeting inflammation by flavonoids: novel therapeutic strategy for metabolic disorders. Int J Mol Sci. 2019;20:4957.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee Y, Bae C-S, Ahn T. Chlorogenic acid attenuates pro-inflammatory response in the blood of streptozotocin-induced diabetic rats. Lab Anim Res. 2022;38:37.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanter M, Aktas C, Erboga M. Curcumin attenuates testicular damage, apoptotic germ cell death, and oxidative stress in streptozotocin-induced diabetic rats. Mol Nutr Food Res. 2013;57:1578–85.

Article  CAS  PubMed  Google Scholar 

Shrilatha B. Muralidhara null. Early oxidative stress in testis and epididymal sperm in streptozotocin-induced diabetic mice: its progression and genotoxic consequences. Reprod Toxicol. 2007;23:578–87.

Article  CAS  PubMed  Google Scholar 

Kyathanahalli C, Bangalore S, Hanumanthappa K, Muralidhara. Experimental diabetes-induced testicular damage in prepubertal rats. J Diabetes. 2014;6:48–59.

Article  CAS  PubMed  Google Scholar 

Samie A, Sedaghat R, Baluchnejadmojarad T, Roghani M. Hesperetin, a citrus flavonoid, attenuates testicular damage in diabetic rats via inhibition of oxidative stress, inflammation, and apoptosis. Life Sci. 2018;210:132–9.

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