Urticaria Activity Score (UAS) Itching and wheals Scoring ranges from 0 to 3 for each question 0 to 42 points Diary-based Prospective Scores ≤6 signify minimal disease activity; scores ≥28 indicate severe urticaria. 7 https://www.dermallergy.com/resources/csu-library/uas7-pro-calculator Urticaria Control Test (UCT) Disease control Each question is rated on a scale of 0 to 3 0 to 16 points Questionnaire Retrospective A score of ≥12 suggests effective disease control. 3 https://survey.urtikaria.net/ Urticaria Severity Score (USS) Impact on quality of life, duration of itch and swelling, medication Scores range from 0 to 7 for 10 questions; one question (corticosteroid) has double weight; Two questions are scored 0–8 0–93 points 11-Item questionnaire Higher scores indicate a more significant impact on quality of life. - https://www.annallergy.org/article/S1081-1206(10)60120-2/abstract Urticaria Activity and Impact Measure CSU activity and impact during the previous seven days.

Each item scored from 0 to 4

Proxy UAS7 – 0–42

0–74 Nine-item questionnaire The U-AIM represents a practical, retrospective tool to assess disease activity and effect of CSU that does not require daily assessments. 0.8 https://www.annallergy.org/action/showPdf?pii=S1081-1206%2818%2930210-2 Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) pruritus, swelling, daily life, sleep, appearance, limitations Each question is rated on a scale of 1–5 23–115 points 23-Item Assessment Higher scores reflect a more pronounced negative impact on health-related quality of life. 15 https://survey.urtikaria.net/ Cold Urticaria Activity Score Frequency and severity of the signs (wheals and/or angioedema), (2) frequency and severity of the symptoms (e.g. itch and burn), (3) exposure to specific triggers and (4) avoidance of these triggers Recall period for each item is the last 24 hours. Four-point Likert scale with answer options “No” “mild,” “moderate,” “severe” (for questions 1–3); “partially” and “completely” for question 4. Exact score calculation is under development Recall period for each item is the last 24 h ColdUAS will help to determine and monitor disease activity in routine clinical practice and ColdU management, including treatment, which is currently difficult. - https://onlinelibrary.wiley.com/doi/full/10.1111/all.15310 Cholinergic Urticaria Quality of life 5 domains - “symptoms”, “functional life”, “social interaction”, “therapy”, “emotions” Each CholU-QoL item was scored from 0 to 4 points 100 points 25-item questionnaire CholU-QoL is the first instrument with excellent validity and reliability for the assessment of disease-specific QoL impairment in patients with CholU, which may be used as an index instrument to measure the overall CholU-related QoL impairment. - https://survey.urtikaria.net/ Angioedema Activity Score (AAS) Physical discomfort, daily activities, cosmetic impact, global severity Scores range from 0 to 3 for each question 0–15 points Five-Question Assessment Elevated scores indicate higher disease activity. - https://moxie-gmbh.de/products/aas Angioedema Quality of Life Questionnaire (AE-QoL) Functioning, fatigue/mood, fears/shame, food Each question is rated on a scale of 0–5 0–85 points 17-Item Evaluation Higher scores suggest a greater impact on overall quality of life. 6 https://survey.urtikaria.net/ Angioedema Control Test Quality of life, symptoms, therapy 3 https://survey.urtikaria.net/ Dermatology Life Quality Index (DLQI) Symptoms, social activities, work/school, personal relationships, treatment-associated problems Scores range from 0 to 3 for each question 0–30 points Ten-item questionnaire High scores indicate a more pronounced impact on overall quality of life. 2.24–3.10 http://www.dermcalculator.com/dlqi/