Humic acid from vermicompost effectively regulates the redox status and mitigates the progression of experimental periodontitis

Aeschbacher M, Graf C, Schwarzenbach RP et al (2012) Antioxidant properties of humic substances. Environ Sci Technol 46:4916–4925

CAS  PubMed  Google Scholar 

Akbas A, Silan C, Gulpinar MT et al (2015) Renoprotective effect of humic acid on renal ischemia-reperfusion injury: an experimental study in rats. Inflammation 38:2042–2048

CAS  PubMed  Google Scholar 

Al-Maskari AY, Al-Maskari MY, Al-Sudairy S (2011) Oral manifestations and complications of diabetes mellitus: a review. Sultan Qaboos Univ Med J 11:179–186

PubMed  PubMed Central  Google Scholar 

Alves L, Coelho T, de Azevedo, RA et al (2020) Systemic risk indicators for peri-implant diseases in individuals with implant-supported fixed prostheses: a cross-sectional study. Int J Oral Implantol (Berlin, Ger) 13(3):255–266

Google Scholar 

An Y, Zhao J, Xu H et al (2021) Effect of humic acid as a photosensitizer combined with low-energy laser on orthodontic tooth movement in rats. J Dent Sci 17(1):407–414

PubMed  PubMed Central  Google Scholar 

Andrade EF, Orlando DR, Gomes JAS et al (2017) Exercise attenuates alveolar bone loss and anxiety-like behaviour in rats with periodontitis. J Clin Periodontol 44:1153–1163

CAS  PubMed  Google Scholar 

Baldotto MA, Baldotto LEB (2014) Ácidos húmicos. Rev Ceres 61:856–881

Google Scholar 

Benzie IFF, Strain JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Anal Biochem 239:70–76

CAS  PubMed  Google Scholar 

Borgnakke WS, Ylöstalo PV, Taylor GW et al (2013) Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence. J Periodontol 84:S135–S152

PubMed  Google Scholar 

Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254

CAS  PubMed  Google Scholar 

Çalışır M, Akpınar A, Poyraz Ö et al (2019) Humic acid, a polyphenolic substance, decreases alveolar bone loss in experimental periodontitis in rats. J Vet Dent 36:257–265

PubMed  Google Scholar 

Çalışır M, Akpınar A, Poyraz et al (2016) The histopathological and morphometric investigation of the effects of systemically administered humic acid on alveolar bone loss in ligature-induced periodontitis in rats. J Periodontal Res 51:499–507

Çalişir M, Akpinar A, Talmaç AC et al (2018) Humic acid enhances wound healing in the rat palate. Evidence-Based Complement Altern Med 1(2018):1783513

Google Scholar 

Caúla AL, Lira-Junior R, Tinoco EMB et al (2015) Serum creatinine and alkaline phosphatase levels are associated with severe chronic periodontitis. J Periodontal Res 50:793–797

PubMed  Google Scholar 

Cekici A, Kantarci A, Hasturk H et al (2000) Inflammatory and immune pathways in the pathogenesis of periodontal disease. Periodontol 2014(64):57–80

Google Scholar 

Chapple ILC, Matthews JB (2000) The role of reactive oxygen and antioxidant species in periodontal tissue destruction. Periodontol 2007(43):160–232

Google Scholar 

Chen M, Cai W, Zhao S et al (2019) Oxidative stress-related biomarkers in saliva and gingival crevicular fluid associated with chronic periodontitis: a systematic review and meta-analysis. J Clin Periodontol 46:608–622

CAS  PubMed  Google Scholar 

Chen MX, Zhong YJ, Dong QQ et al (2021) Global, regional, and national burden of severe periodontitis, 1990–2019: an analysis of the Global Burden of Disease Study 2019. J Clin Periodontol 48:1165–1188

PubMed  Google Scholar 

Costa KB, Leite HR, Garcia BCC et al (2022) Storage duration affects the quantification of oxidative stress markers in the gastrocnemius, heart, and brain of mice submitted to a maximum exercise. Biopreserv Biobank 20:3–11

CAS  PubMed  Google Scholar 

Cullinan MP, Seymour GJ (2000) Periodontal disease and systemic illness: will the evidence ever be enough? Periodontol 2013(62):271–286

Google Scholar 

Dai J, Ma Y, Shi M et al (2016) Initial changes in alveolar bone volume for sham-operated and ovariectomized rats in ligature-induced experimental periodontitis. Clin Oral Investig 20:581–588

PubMed  Google Scholar 

de Araújo RF, Souza TO, de Moura LM et al (2013) Atorvastatin decreases bone loss, inflammation and oxidative stress in experimental periodontitis. PLoS ONE 8:1–7

Google Scholar 

de Molon RS, de Avila ED, Boas Nogueira AV et al (2014) Evaluation of the host response in various models of induced periodontal disease in mice. J Periodontol 85:465–477

PubMed  Google Scholar 

de Molon RS, Park CH, Jin Q et al (2018) Characterization of ligature-induced experimental periodontitis. Microsc Res Tech 81:1412–1421

PubMed  Google Scholar 

De Melo BAG, Motta FL, Santana MHA (2016) Humic acids: structural properties and multiple functionalities for novel technological developments. Mater Sci Eng C 62:967–974

Google Scholar 

Dobbss LB, Canellas LP, Olivares FL et al (2010) Bioactivity of chemically transformed humic matter from vermicompost on plant root growth. J Agric Food Chem 58:3681–3688

CAS  PubMed  Google Scholar 

Dores-Silva PR, Landgraf MD, Maria MO (2013) Processo de estabilização de resíduos orgânicos: vermicompostagem versus compostagem. Quim Nova 36:640–645

CAS  Google Scholar 

Dores-Silva PR, Landgraf MD, Rezende MOO (2018) Humification process in different kinds of organic residue by composting and vermicomposting: have microbioreactors really accelerated the process? Environ Sci Pollut Res 25:17490–17498

CAS  Google Scholar 

Gholami H, Saharkhiz MJ, Raouf Fard F et al (2018) Humic acid and vermicompost increased bioactive components, antioxidant activity and herb yield of Chicory (Cichorium intybus L.). Biocatal Agric Biotechnol 14:286–292

Hamza ZK, Hathout AS, Ostroff G et al (2022) Assessment of the protective effect of yeast cell wall β-glucan encapsulating humic acid nanoparticles as an aflatoxin B1 adsorbent in vivo. J Biochem Mol Toxicol 36(1):e22941

CAS  PubMed  Google Scholar 

Hartenstein R, Hartenstein F (1981) Physicochemical changes effected in activated sludge by the earthworm Eisenia foetida. J Environ Qual 10:377–381

CAS  Google Scholar 

Hriciková S, Kožárová I, Hudáková N et al (2023) Humic substances as a versatile intermediary. Life 13:858

PubMed  PubMed Central  Google Scholar 

Huang J, Xu P, Shao M et al (2023) Humic acids alleviate dextran sulfate sodium-induced colitis by positively modulating gut microbiota. Front Microbiol 12(14):1147110

Google Scholar 

Jansen Van Rensburg CE, Naude PJ (2009) Potassium humate inhibits complement activation and the production of inflammatory cytokines in vitro. Inflammation 32:270–276

Joone GK, Jansen van Rensburg CE (2004) An in vitro investigation of the anti-inflammatory properties of potassium humate. Inflammation 28:169–174

Kamata Y, Kessoku T, Shimizu T et al (2022) Periodontal treatment and usual care for nonalcoholic fatty liver disease: a multicenter, randomized controlled trial. Clin Transl Gastroenterol 13:e00520

PubMed  PubMed Central  Google Scholar 

Karadirek Ş, Kanmaz N, Balta Z et al (2016) Determination of total antioxidant capacity of humic acids using CUPRAC, Folin-Ciocalteu, noble metal nanoparticle- and solid–liquid extraction-based methods. Talanta 153:120–129

CAS  PubMed  Google Scholar 

Khan R, Jain P, Zakir F et al (2022) Quality and in vivo assessment of a fulvic acid complex: a validation study. Sci Pharm 90:33

Khil’ko SL, Efimova IV, Smirnova OV (2011) Antioxidant properties of humic acids from brown coal. Solid Fuel Chem 45:367–371

Kshirsagar AV, Moss KL, Elter JR et al (2005) Periodontal disease is associated with renal insufficiency in the Atherosclerosis Risk in Communities (ARIC) study. Am J Kidney Dis 45:650–657

PubMed  Google Scholar 

Kumar J, Teoh SL, Das S et al (2017) Oxidative stress in oral diseases: understanding its relation with other systemic diseases. J Fam Med Prim Care 8:693

Google Scholar 

Levine RL, Williams JA, Stadtman EP et al (1994) Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol 233:346–357

CAS  PubMed  Google Scholar 

Loesche WJ, Grossman NS (2001) Periodontal disease as a specific, albeit chronic, infection: diagnosis and treatment. Clin Microbiol Rev 14:727–752

CAS  PubMed  PubMed Central  Google Scholar 

Machado W, Franchini JC, de Fátima GM et al (2020) Spectroscopic characterization of humic and fulvic acids in soil aggregates, Brazil. Heliyon 6:e04078

PubMed  PubMed Central  Google Scholar 

Malcolm RL (2015) Variations between humic substances isolated from soils, stream waters, and groundwaters as revealed by 13C-NMR spectroscopy. In: Humic substances in soil and crop sciences: selected readings. John Wiley & Sons, Ltd, pp 13–35

Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47:469–474

CAS  PubMed  Google Scholar 

Messora MR, Oliveira LFF, Foureaux RC et al (2013) Probiotic therapy reduces periodontal tissue destruction and improves the intestinal morphology in rats with ligature-induced periodontitis. J Periodontol 84:1818–1826

PubMed  Google Scholar 

Mirza MA, Ahmad N, Agarwal SP et al (2011) Comparative evaluation of humic substances in oral drug delivery. Results Pharma Sci 1:26

Google Scholar 

Mondal A, Goswami L, Hussain N et al (2020) Detoxification and eco-friendly recycling of brick kiln coal ash using Eisenia fetida: a clean approach through vermitechnology. Chemosphere 244:125470

CAS  PubMed  Google Scholar 

Mudroňová D, Karaffová V, Semjon B et al (2021) Effects of dietary supplementation of humic substances on production parameters, immune status and gut microbiota of laying hens. Agriculture 11:744

Google Scholar 

Murbach TS, Glávits R, Endres JR et al (2020) A toxicological evaluation of a fulvic and humic acids preparation. Toxicol Reports 7:1242–1254

CAS  Google Scholar 

Nazir M, Al-Ansari A, Al-Khalifa K et al (2020) Global prevalence of periodontal disease and lack of its surveillance. Sci World J 2020:2146160

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