Olive oil and castor oil-based self-nanoemulsifying drug delivery system of flurbiprofen can relieve peripheral pain and inflammation through reduction of oxidative stress and inflammatory biomarkers: a comprehensive formulation and pharmacological insights

Abd-Elhakeem E, Teaima MH, Abdelbary GA, El Mahrouk GM (2019) Bioavailability enhanced clopidogrel-loaded solid SNEDDS: development and in-vitro/in-vivo characterization. J Drug Deliv Sci Technol 49:603–614

Article  Google Scholar 

Alblihed MA (2020) Astragalin attenuates oxidative stress and acute inflammatory responses in carrageenan-induced paw edema in mice. Mol Biol Rep 47:6611–6620

Article  PubMed  Google Scholar 

Alothaid H, Aldughaim MS, Yusuf AO, Yezdani U, Alhazmi A, Habibullah MM, Khan MG (2021) A comprehensive study of the basic formulation of supersaturated self-nanoemulsifying drug delivery systems (SNEDDS) of albendazolum. Drug Deliv 28:2119–2126

Article  PubMed  PubMed Central  Google Scholar 

Alqahtani MS, Kazi M, Alsenaidy MA, Ahmad MZ (2021) Advances in oral drug delivery. Front Pharmacol 12:618411

Article  PubMed  PubMed Central  Google Scholar 

Amin A, Akhtar MF, Saleem A, Sharif A, Shah S, Khan MI, Anwar F, Abbas G, Zubair HM, Sohail MF (2022) Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats. Inflammopharmacology 30:2285–2300

Article  PubMed  Google Scholar 

Annisa R, Yuwono M, Hendradi E (2020) Effect of vegetable oil on self-nanoemulsifying drug delivery system of Dayak Onion [Eleutherine palmifolia (L.) Merr.] extract using hydrophilic-lipophilic balance approach: formulation, characterization. Int J Drug Delivery Technol 10:210–216

Article  Google Scholar 

Ansari MJ, Alshetaili A, Aldayel IA, Alablan FM, Alsulays B, Alshahrani S, Alalaiwe A, Ansari MN, Ur Rehman N, Shakeel F (2020) Formulation, characterization, in vitro and in vivo evaluations of self-nanoemulsifying drug delivery system of luteolin. J Taibah Univer Sci 14:1386–1401

Article  Google Scholar 

Ayed OBH, Lassoued MA, Bahloul B, Sfar S (2021) Self-emulsifying drug delivery system for improved dissolution and oral absorption of quetiapine fumarate: investigation of drug release mechanism and in-vitro intestinal permeability. Iranian J Pharmaceut Res: IJPR 20:381

Google Scholar 

Balata GF, Essa EA, Shamardl HA, Zaidan SH, Abourehab MA (2016) Self-emulsifying drug delivery systems as a tool to improve solubility and bioavailability of resveratrol. Drug des Devel Ther. https://doi.org/10.2147/DDDT.S95905

Article  PubMed  PubMed Central  Google Scholar 

Bannow J, Yorulmaz Y, Löbmann K, Müllertz A, Rades T (2020) Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors. Int J Pharm 575:118960

Article  PubMed  Google Scholar 

Batool A, Arshad R, Razzaq S, Nousheen K, Kiani MH, Shahnaz G (2020) Formulation and evaluation of hyaluronic acid-based mucoadhesive self nanoemulsifying drug delivery system (SNEDDS) of tamoxifen for targeting breast cancer. Int J Biol Macromol 152:503–515

Article  PubMed  Google Scholar 

Bilal Y, Emrah A (2015) Spectrofluorometric and uv spectrophotometric methods for the determination of flurbiprofen in pharmaceutical preparations. J Pharmaceut Anal 4:1–8

Google Scholar 

Bindhani S, Mohapatra S (2019) Supersaturated self emulsifying drug delivery system: A recent approach. Res J Pharm Technol 12:6165–6173

Article  Google Scholar 

Čerpnjak K, Zvonar A, Vrečer F, Gašperlin M (2015) Development of a solid self-microemulsifying drug delivery system (SMEDDS) for solubility enhancement of naproxen. Drug Dev Ind Pharm 41:1548–1557

Article  PubMed  Google Scholar 

Charoo NA, AaA S, Kohli K, Pillai K, Rahman Z (2008) Improvement in bioavailability of transdermally applied flurbiprofen using tulsi (Ocimum sanctum) and turpentine oil. Colloids Surf B Biointerfaces 65:300–307

Article  PubMed  Google Scholar 

Ching YC, Gunathilake TMS, Chuah CH, Ching KY, Singh R, Liou N-S (2019) Curcumin/Tween 20-incorporated cellulose nanoparticles with enhanced curcumin solubility for nano-drug delivery: characterization and in vitro evaluation. Cellulose 26:5467–5481

Article  Google Scholar 

Daar J, Khan A, Khan J, Khan A, Khan GM (2017) Studies on self-nanoemulsifying drug delivery system of flurbiprofen employing long, medium and short chain triglycerides. Pak J Pharm Sci 30:601–606

PubMed  Google Scholar 

Dash RN, Mohammed H, Humaira T, Ramesh D (2015) Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution. Saudi Pharmaceut J 23:528–540

Article  Google Scholar 

Dinarvand R, Moghadam S, Sheikhi A, Atyabi F (2005) Effect of surfactant HLB and different formulation variables on the properties of poly-D, L-lactide microspheres of naltrexone prepared by double emulsion technique. J Microencapsul 22:139–151

Article  PubMed  Google Scholar 

Eid AM, El-Enshasy HA, Aziz R, Elmarzugi NA (2014) The preparation and evaluation of self-nanoemulsifying systems containing Swietenia oil and an examination of its anti-inflammatory effects. Int J Nanomed 15:4685–4695

Google Scholar 

Gao H, Jia H, Dong J, Yang X, Li H, Ouyang D (2021) Integrated in silico formulation design of self-emulsifying drug delivery systems. Acta Pharmaceutica Sinica B 11:3585–3594

Article  PubMed  PubMed Central  Google Scholar 

Gravallese EM, Firestein GS (2023) Rheumatoid arthritis—common origins, divergent mechanisms. N Engl J Med 388:529–542

Article  PubMed  Google Scholar 

Gul U, Khan MI, Madni A, Sohail MF, Rehman M, Rasul A, Peltonen L (2022) Olive oil and clove oil-based nanoemulsion for topical delivery of terbinafine hydrochloride: in vitro and ex vivo evaluation. Drug Deliv 29:600–612

Article  PubMed  PubMed Central  Google Scholar 

Hanif R, Khan MI, Madni A, Akhtar MF, Sohail MF, Saleem A, Rehman M, Usmani SJ, Khan A, Masood A (2023) Polyoxyethylene lauryl ether (brij-35) and poloxamer 407–based non-ionic surfactant vesicles for dissolution enhancement of tacrolimus. J Pharmaceut Innov. https://doi.org/10.1007/s12247-023-09737-2

Article  Google Scholar 

Hasan HM, Leanpolchareanchai J, Jintapattanakit A (2015) Preparation of virgin coconut oil nanoemulsions by phase inversion temperature method. Adv Mater Res 1060:99–102

Article  Google Scholar 

Hira S, Saleem U, Anwar F, Raza Z, Rehman AU, Ahmad B (2020) In silico study and pharmacological evaluation of eplerinone as an anti-alzheimer’s drug in stz-induced alzheimer’s disease model. ACS Omega 5:13973–13983

Article  PubMed  PubMed Central  Google Scholar 

Hussain A, Khan GM, Jan SU, Shah SU, Shah K, Akhlaq M, Rahim N, Nawaz A, Wahab A (2012) Effect of olive oil on transdermal penetration of flurbiprofen from topical gel as enhancer. Pak J Pharm Sci 25:3218

Google Scholar 

Jaiswal P, Aggarwal G, Harikumar SL, Singh K (2014) Development of self-microemulsifying drug delivery system and solid-self-microemulsifying drug delivery system of telmisartan. Int J Pharmaceut Invest 4:195

Article  Google Scholar 

Kassem AA, Mohsen AM, Ahmed RS, Essam TM (2016) Self-nanoemulsifying drug delivery system (SNEDDS) with enhanced solubilization of nystatin for treatment of oral candidiasis: Design, optimization, in vitro and in vivo evaluation. J Mol Liq 218:219–232

Article  Google Scholar 

Katebian M, Pedram M, Dehghan M, Mansoori K, Lalehpoor M, Kosarifard F (2023) A comparison between therapeutic effects of Salvia Officinalis Extract, meloxicam and dexamethasone following acute sciatic nerve injury due to analgesic drug injection in rats. Adv Oral Maxillofacial Surg. https://doi.org/10.1016/j.adoms.2023.100460

Article  Google Scholar 

Ke Z, Hou X, Jia X-B (2016) Design and optimization of self-nanoemulsifying drug delivery systems for improved bioavailability of cyclovirobuxine D. Drug des Devel Ther. https://doi.org/10.2147/DDDT.S106356

Article  PubMed  PubMed Central  Google Scholar 

Khan MI, Madni A, Peltonen L (2016) Development and in-vitro characterization of sorbitan monolaurate and poloxamer 184 based niosomes for oral delivery of diacerein. Eur J Pharm Sci 95:88–95

Article  PubMed  Google Scholar 

Khani S, Keyhanfar F, Amani A (2016) Design and evaluation of oral nanoemulsion drug delivery system of mebudipine. Drug Deliv 23:2035–2043

Article  PubMed  Google Scholar 

Kim RM, Jang D-J, Kim YC, Yoon J-H, Min KA, Maeng H-J, Cho KH (2018) Flurbiprofen-loaded solid SNEDDS preconcentrate for the enhanced solubility, in-vitro dissolution and bioavailability in rats. Pharmaceutics 10:247

Article  PubMed  PubMed Central  Google Scholar 

Li H, Niu S, Lu C (2017) Pyrolysis characteristics of castor oil through thermogravimetric coupled with fourier transform infrared spectroscopy. Procedia Engineering 205:3705–3710

Article  Google Scholar 

Marasini N, Yan YD, Poudel BK, Choi HG, Yong CS, Kim JO (2012) Development and optimization of self-nanoemulsifying drug delivery system with enhanced bioavailability by Box-Behnken design and desirability function. J Pharm Sci 101:4584–4596

Article  PubMed  Google Scholar 

Mohamed HI, El-Kamel AH, Hammad GO, Heikal LA (2022) Design of targeted flurbiprofen biomimetic nanoparticles for management of arthritis: in vitro and in vivo appraisal. Pharmaceutics 14:140

Article 

留言 (0)

沒有登入
gif