Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MBF et al (2020) Multisystem inflammatory syndrome in U.S. children and adolescents. New England J Med 383(4):334–46. https://doi.org/10.1056/NEJMoa2021680

Article  CAS  Google Scholar 

Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P (2020) Hyperinflammatory shock in children during COVID-19 pandemic. The Lancet 395(10237):1607–1608. https://doi.org/10.1016/S0140-6736(20)31094-1

Article  CAS  Google Scholar 

Dufort EM, Koumans EH, Chow EJ, Rosenthal EM, Muse A, Rowlands J et al (2020) Multisystem inflammatory syndrome in children in New York State. N Engl J Med 383(4):347–358. https://doi.org/10.1056/NEJMoa2021756

Article  CAS  PubMed  Google Scholar 

Whittaker E, Bamford A, Kenny J, Kaforou M, Jones CE, Shah P et al (2020) Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA 324(3):259. https://doi.org/10.1001/jama.2020.10369

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z et al (2020) Epidemiology of COVID-19 among children in China. Pediatrics. 145(6):e20200702. https://doi.org/10.1542/peds.2020-0702

Article  PubMed  Google Scholar 

CDC (2019) Health Alert Network (HAN): Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease (COVID-19). https://emergency.cdc.gov/han/2020/han00432.asp. Accessed 21 Apr 2024

World Health Organisation (2020) Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19. https://www.who.int/news-room/commentaries/detail/multisystem-inflammatory-syndrome-in-children-and-adolescents-with-covid-19. Accessed 21 Apr 2024

Acevedo L, Piñeres-Olave BE, Niño-Serna LF, Vega LM, Gomez IJA, Chacón S et al (2021) Mortality and clinical characteristics of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 in critically ill patients: an observational multicenter study (MISCO study). BMC Pediatr 21(1):516. https://doi.org/10.1186/s12887-021-02974-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Capone CA, Subramony A, Sweberg T, Schneider J, Shah S, Rubin L et al (2020) Characteristics, cardiac involvement, and outcomes of multisystem inflammatory syndrome of childhood associated with severe acute respiratory syndrome coronavirus 2 infection. J Pediatr 224:141–145. https://doi.org/10.1016/j.jpeds.2020.06.044

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sık G, Inamlık A, Akçay N, Kesici S, Aygun F, Kendırlı T et al (2023) Mortality risk factors among critically ill children with MIS-C in PICUs: a multicenter study. Pediatr Res 94(2):730–737. https://doi.org/10.1038/s41390-023-02518-0

Article  CAS  PubMed  Google Scholar 

Zou H, Lu J, Liu J, Wong JHY, Cheng S, Li Q et al (2021) Characteristics of pediatric multi-system inflammatory syndrome (PMIS) associated with COVID-19: a meta-analysis and insights into pathogenesis. Int J Infect Dis 102:319–26

Article  CAS  PubMed  Google Scholar 

Nakra N, Blumberg D, Herrera-Guerra A, Lakshminrusimha S (2020) Multi-system inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection: review of clinical presentation, hypothetical pathogenesis, and proposed management. Children 7(7):69. https://doi.org/10.3390/children7070069

Article  PubMed  PubMed Central  Google Scholar 

Ucan B, KaynakSahap S, Cinar HG, TasciYildiz Y, Uner C, Polat M et al (2022) Multisystem inflammatory syndrome in children associated with SARS-CoV-2: extracardiac radiological findings. Br J Radiol. 95(1129):20210570. https://doi.org/10.1259/bjr.20210570

Article  PubMed  Google Scholar 

Fenlon EP III, Chen S, Ruzal-Shapiro CB, Jaramillo D, Maddocks ABR (2021) Extracardiac imaging findings in COVID-19-associated multisystem inflammatory syndrome in children. Pediatr Radiol 51(5):831–839. https://doi.org/10.1007/s00247-020-04929-1

Article  Google Scholar 

Hameed S, Elbaaly H, Reid CEL, Santos RMF, Shivamurthy V, Wong J et al (2021) Spectrum of imaging findings at chest radiography, US, CT, and MRI in multisystem inflammatory syndrome in children associated with COVID-19. Radiology 298(1):E1-10. https://doi.org/10.1148/radiol.2020202543

Article  PubMed  Google Scholar 

Ilieva E, Kostadinova V, Tzotcheva I, Rimpova N, Paskaleva Y, Lazova S (2022) Abdominal and thoracic imaging features in children with MIS-C. Gastroenterol Insights 13(4):313–325. https://doi.org/10.3390/gastroent13040032

Article  Google Scholar 

Hwang M, Wilson K, Wendt L, Pohlman J, Densmore E, Kaeppler C et al (2021) The great gut mimicker: a case report of MIS-C and appendicitis clinical presentation overlap in a teenage patient. BMC Pediatr. 21(1):1–5. https://doi.org/10.1186/s12887-021-02724-x

Article  CAS  Google Scholar 

Ramosaj-Morina A, Keka-Sylaj A, Baloku A, Gjaka P, Podrimaj A (2023) Coincidental or mimicking acute appendicitis secondary to MIS-C associated with SARS-CoV-2: a case report. SAGE Open Med Case Rep 1:11. https://doi.org/10.1177/2050313X231167375

Article  Google Scholar 

Jonat B, Gorelik M, Boneparth A, Geneslaw AS, Zachariah P, Shah A et al (2021) Multisystem inflammatory syndrome in children associated with coronavirus disease 2019 in a children’s hospital in New York City: patient characteristics and an institutional protocol for evaluation, management, and follow-up. Pediatr Crit Care Med 22(3):e178–e191. https://doi.org/10.1097/PCC.0000000000002598

Article  PubMed  Google Scholar 

Blumfield E, Levin TL, Kurian J, Lee EY, Liszewski MC (2021) Imaging findings in multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease (COVID-19). Am J Roentgenol 216(2):507–517. https://doi.org/10.2214/AJR.20.24032

Article  Google Scholar 

Alkan G, Sert A, Oz SKT, Emiroglu M, Yılmaz R (2021) Clinical features and outcome of MIS-C patients: an experience from Central Anatolia. Clin Rheumatol 40(10):4179–4189. https://doi.org/10.1007/s10067-021-05754-z

Article  PubMed  PubMed Central  Google Scholar 

Levy N, Koppel JH, Kaplan O, Yechiam H, Shahar-Nissan K, Cohen NK et al (2022) Severity and incidence of multisystem inflammatory syndrome in children during 3 SARS-CoV-2 pandemic waves in Israel. JAMA 327(24):2452. https://doi.org/10.1001/jama.2022.8025

Article  CAS  PubMed  PubMed Central  Google Scholar